Plant ID: NPO16831
Plant Latin Name: Hypericum Patulum
Taxonomy Genus: Hypericum
Taxonomy Family: Hypericaceae
NCBI TaxonomyDB:
212239
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC98549
Ingredient ID: NPC94610
Ingredient ID: NPC8943
Ingredient ID: NPC87009
Ingredient ID: NPC82136
Ingredient ID: NPC79340
Ingredient ID: NPC73532
Ingredient ID: NPC69460
Ingredient ID: NPC64469
Ingredient ID: NPC60120
Ingredient ID: NPC483050
Ingredient ID: NPC483049
Ingredient ID: NPC483048
Ingredient ID: NPC472688
Ingredient ID: NPC472676
Ingredient ID: NPC45077
Ingredient ID: NPC44758
Ingredient ID: NPC44619
Ingredient ID: NPC40465
Ingredient ID: NPC3994
Ingredient ID: NPC33747
Ingredient ID: NPC32104
Ingredient ID: NPC310038
Ingredient ID: NPC308485
Ingredient ID: NPC30565
Ingredient ID: NPC300928
Ingredient ID: NPC289754
Ingredient ID: NPC286941
Ingredient ID: NPC2859
Ingredient ID: NPC2818
Ingredient ID: NPC276919
Ingredient ID: NPC275463
Ingredient ID: NPC269513
Ingredient ID: NPC269184
Ingredient ID: NPC263641
Ingredient ID: NPC263344
Ingredient ID: NPC26272
Ingredient ID: NPC253628
Ingredient ID: NPC250290
Ingredient ID: NPC246162
Ingredient ID: NPC244871
Ingredient ID: NPC243320
Ingredient ID: NPC240645
Ingredient ID: NPC23811
Ingredient ID: NPC234962
Ingredient ID: NPC231435
Ingredient ID: NPC230894
Ingredient ID: NPC229177
Ingredient ID: NPC227889
Ingredient ID: NPC224631
Ingredient ID: NPC223081
Ingredient ID: NPC220644
Ingredient ID: NPC218109
Ingredient ID: NPC21165
Ingredient ID: NPC210582
Ingredient ID: NPC209647
Ingredient ID: NPC206168
Ingredient ID: NPC203536
Ingredient ID: NPC203155
Ingredient ID: NPC202291
Ingredient ID: NPC198079
Ingredient ID: NPC197544
Ingredient ID: NPC190870
Ingredient ID: NPC190764
Ingredient ID: NPC190302
Ingredient ID: NPC184181
Ingredient ID: NPC179594
Ingredient ID: NPC178795
Ingredient ID: NPC174186
Ingredient ID: NPC168397
Ingredient ID: NPC16156
Ingredient ID: NPC153283
Ingredient ID: NPC147680
Ingredient ID: NPC138883
Ingredient ID: NPC135846
Ingredient ID: NPC132739
Ingredient ID: NPC128927
Ingredient ID: NPC124479
Ingredient ID: NPC124349
Ingredient ID: NPC12349
Ingredient ID: NPC12332
Ingredient ID: NPC121589
Ingredient ID: NPC113385
Ingredient ID: NPC108435
Ingredient ID: NPC108151
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials |
---|
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
CA12,MAPT,CA12,MAPT
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CA12,CA7
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CA12,CA7
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CA12,CA7
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
CA12,CA7
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
CA12,CA7
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
MAPT
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA12
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
MAPT
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA12
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
MAPT
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
CA12
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA12
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
MAPT
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
MAPT
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
CA7
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CA12
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
MAPT
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
MAPT
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
CA12
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
CA12
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
CA7
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CA12
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
MAPT
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
CA12
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CA12
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CA12
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
CA12
|