Diuretic; Purgative; Vulnerary
Brazil; Italy; Bangladesh; Sudan; Guinea; Cambodia; France; Bahamas; Ethiopia; Rwanda; Tanzania; Somalia; Peru; Argentina; Bolivia; Cameroon; Malawi; Ecuador; Benin; Algeria; Cuba; Venezuela; Zambia; Cape Verde; United States; Trinidad and Tobago; Zimbabwe; China; Germany; Dominican Republic; Belize; Sierra Leone; Spain; Nigeria; Libya; Gambia; Philippines; Indonesia; New Caledonia; Mauritius; Morocco; Seychelles; Namibia; Guinea-Bissau; Thailand; Honduras; Haiti; Bulgaria; Jamaica; Albania; Angola; Portugal; Mexico; Tunisia; South Africa; India; United Kingdom; Senegal; Mozambique; Uganda; Greece; Burundi; Kenya; Fiji; Botswana
Ingredient ID: NPC96613
Ingredient ID: NPC90232
Ingredient ID: NPC85813
Ingredient ID: NPC84771
Ingredient ID: NPC83702
Ingredient ID: NPC77249
Ingredient ID: NPC76314
Ingredient ID: NPC73921
Ingredient ID: NPC71394
Ingredient ID: NPC69871
Ingredient ID: NPC68267
Ingredient ID: NPC67917
Ingredient ID: NPC57801
Ingredient ID: NPC56448
Ingredient ID: NPC48957
Ingredient ID: NPC470772
Ingredient ID: NPC4465
Ingredient ID: NPC43520
Ingredient ID: NPC43360
Ingredient ID: NPC39426
Ingredient ID: NPC37132
Ingredient ID: NPC3707
Ingredient ID: NPC34903
Ingredient ID: NPC331129
Ingredient ID: NPC307945
Ingredient ID: NPC307729
Ingredient ID: NPC3016
Ingredient ID: NPC301585
Ingredient ID: NPC299505
Ingredient ID: NPC298802
Ingredient ID: NPC297117
Ingredient ID: NPC29678
Ingredient ID: NPC295263
Ingredient ID: NPC294548
Ingredient ID: NPC294409
Ingredient ID: NPC293249
Ingredient ID: NPC292825
Ingredient ID: NPC28657
Ingredient ID: NPC286052
Ingredient ID: NPC283011
Ingredient ID: NPC279974
Ingredient ID: NPC274729
Ingredient ID: NPC27407
Ingredient ID: NPC27349
Ingredient ID: NPC26974
Ingredient ID: NPC267741
Ingredient ID: NPC266359
Ingredient ID: NPC264833
Ingredient ID: NPC263785
Ingredient ID: NPC26229
Ingredient ID: NPC261831
Ingredient ID: NPC260691
Ingredient ID: NPC258220
Ingredient ID: NPC257383
Ingredient ID: NPC255647
Ingredient ID: NPC249578
Ingredient ID: NPC249194
Ingredient ID: NPC247835
Ingredient ID: NPC243728
Ingredient ID: NPC23925
Ingredient ID: NPC238041
Ingredient ID: NPC23795
Ingredient ID: NPC234560
Ingredient ID: NPC234106
Ingredient ID: NPC233481
Ingredient ID: NPC231051
Ingredient ID: NPC230923
Ingredient ID: NPC23046
Ingredient ID: NPC230301
Ingredient ID: NPC230085
Ingredient ID: NPC229475
Ingredient ID: NPC229216
Ingredient ID: NPC228906
Ingredient ID: NPC22260
Ingredient ID: NPC222153
Ingredient ID: NPC222147
Ingredient ID: NPC220759
Ingredient ID: NPC219560
Ingredient ID: NPC217914
Ingredient ID: NPC216630
Ingredient ID: NPC216187
Ingredient ID: NPC216127
Ingredient ID: NPC2114
Ingredient ID: NPC209970
Ingredient ID: NPC207632
Ingredient ID: NPC202651
Ingredient ID: NPC201950
Ingredient ID: NPC201844
Ingredient ID: NPC199773
Ingredient ID: NPC196924
Ingredient ID: NPC196561
Ingredient ID: NPC196370
Ingredient ID: NPC196227
Ingredient ID: NPC19404
Ingredient ID: NPC189092
Ingredient ID: NPC187445
Ingredient ID: NPC179798
Ingredient ID: NPC17599
Ingredient ID: NPC173690
Ingredient ID: NPC168030
Ingredient ID: NPC163755
Ingredient ID: NPC162742
Ingredient ID: NPC159630
Ingredient ID: NPC158963
Ingredient ID: NPC155461
Ingredient ID: NPC154186
Ingredient ID: NPC153958
Ingredient ID: NPC151250
Ingredient ID: NPC149184
Ingredient ID: NPC148403
Ingredient ID: NPC145444
Ingredient ID: NPC145277
Ingredient ID: NPC143008
Ingredient ID: NPC142349
Ingredient ID: NPC142027
Ingredient ID: NPC139473
Ingredient ID: NPC138222
Ingredient ID: NPC136932
Ingredient ID: NPC134717
Ingredient ID: NPC126750
Ingredient ID: NPC126503
Ingredient ID: NPC123965
Ingredient ID: NPC120151
Ingredient ID: NPC119802
Ingredient ID: NPC119036
Ingredient ID: NPC116726
Ingredient ID: NPC113733
Ingredient ID: NPC108202
Ingredient ID: NPC107860
Ingredient ID: NPC107629
Ingredient ID: NPC106770
Ingredient ID: NPC105354
Ingredient ID: NPC105267
Ingredient ID: NPC104050
Ingredient ID: NPC101366
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 2 | CYP2C9 | Cytochrome P450 2C9 | P11712 | CHEMBL3397 |
Therapeutic Target | Enzyme | AKR1C3 | Aldo-keto-reductase family 1 member C3 | P42330 | CHEMBL4681 |
Therapeutic Target | Enzyme | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
Therapeutic Target | Fatty acid binding protein family | FABP4 | Fatty acid binding protein adipocyte | P15090 | CHEMBL2083 |
Therapeutic Target | Fatty acid binding protein family | FABP5 | Fatty acid binding protein epidermal | Q01469 | CHEMBL3674 |
Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
Therapeutic Target | Lyase | CA4 | Carbonic anhydrase IV | P22748 | CHEMBL3729 |
Therapeutic Target | Nuclear hormone receptor subfamily 1 | PPARA | Peroxisome proliferator-activated receptor alpha | Q07869 | CHEMBL239 |
Therapeutic Target | Nuclear hormone receptor subfamily 1 | RORC | Nuclear receptor ROR-gamma | P51449 | CHEMBL1741186 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESRRA | Estrogen-related receptor alpha | P11474 | CHEMBL3429 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESRRB | Estrogen-related receptor beta | O95718 | CHEMBL3751 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR2 | Estrogen receptor beta | Q92731 | CHEMBL242 |
Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
Therapeutic Target | Oxidoreductase | AOX1 | Aldehyde oxidase | Q06278 | CHEMBL3257 |
Therapeutic Target | Oxidoreductase | PTGS2 | Cyclooxygenase-2 | P35354 | CHEMBL230 |
Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
Therapeutic Target | Protein Kinase | MAP2K4 | Dual specificity mitogen-activated protein kinase kinase 4 | P45985 | CHEMBL2897 |
Therapeutic Target | Serine protease | DPP4 | Dipeptidyl peptidase IV | P27487 | CHEMBL284 |
Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR4 | G-protein coupled receptor 120 | Q5NUL3 | CHEMBL5339 |
Therapeutic Target | Small molecule receptor (family A GPCR) | FFAR1 | Free fatty acid receptor 1 | O14842 | CHEMBL4422 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 106 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00523965 | Combination Therapy in Indian Visceral Leishmaniasis | Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT02686853 | Efficacy of Intrathecal Administration of Liposomal Amphotericin B in Cryptococcal Meningitis | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT01310738 | Efficacy and Safety Study of Drugs for Treatment of Visceral Leishmaniasis in Brazil | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00590538 | Phenylbutyrate/Genistein Duotherapy in Delta F508-Heterozygotes (for Cystic Fibrosis) | cystic fibrosis | Genistein (NPC39426) | NP level |
NCT00145249 | Amphotericin Alone or in Combination With Fluconazole for AIDS-Associated Meningitis | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT02629419 | CAMB/MAT2203 in Patients With Mucocutaneous Candidiasis | Chronic mucocutaneous candidosis | Amphotericin B (NPC67917) | NP level |
NCT01293643 | A Study to Compare the Efficacy and Safety of a Combination of Ketoconazole and Clindamycin Compared to Tetracycline/Amphotericin B Combination Cream for the Treatment of Bacterial Vaginosis and Vaginal Candidiasis (P08077) | bacterial vaginosis;vulvovaginal candidiasis | Amphotericin B (NPC67917) | NP level |
NCT03636659 | Steady State Global Bioequivalence Study of Amphotericin B Liposome for Injection 50 mg/ Vial in Fed Condition | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00986713 | Value of Amphotericin B Inhalation for Prophylaxis of Invasive Pulmonary Aspergillosis After Renal Transplantation | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT00272844 | Treatment of the Cholesterol Defect in Smith-Lemli-Opitz Syndrome | Smith-Lemli-Opitz syndrome | Cholesterol (NPC28657) | NP level |
NCT04267497 | Nebulised Liposomal Amphotericin for Invasive Pulmonary Aspergillosis (NAIFI01 Study) | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT00876824 | To Study the Effect Of Single Infusions Of Amphotericin B Lipid Preparations in Treatment of Patients Of Kala Azar | Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT03187691 | Safety and PK of Oral Encochleated Amphotericin B (CAMB/MAT2203) for Antifungal Prophylaxis in Patients Undergoing Induction Chemotherapy for Acute Myelogenous and Lymphoblastic Leukaemia | acute lymphoblastic leukemia;acute myeloid leukemia | Amphotericin B (NPC67917) | NP level |
NCT05468372 | Amphotericin Versus Posaconazole for Pulmonary Mucormycosis | mucormycosis | Amphotericin B (NPC67917) | NP level |
NCT00005827 | Genistein in Treating Patients With Stage II, Stage III, or Stage IV Prostate Cancer | prostate cancer | Genistein (NPC39426) | NP level |
NCT02567799 | BIO 300 Non-Small Cell Lung Cancer Study | non-small cell lung carcinoma | Genistein (NPC39426) | NP level |
NCT00000776 | Dexamethasone in Cryptococcal Meningitis | intracranial hypertension;cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT02025491 | Liposomal Amphotericin in Disseminated Leishmaniasis | Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00832208 | Open-Label, Sequential Step, Safety and Efficacy Study to Determine the Optimal Single Dose of Ambisome for Patients With VL | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT03327727 | VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT00815516 | Study to Compare the Efficacy and Safety of Micafungin Versus Conventional Amphotericin B for the Treatment of Neonatal Candidiasis | candidiasis | Amphotericin B (NPC67917) | NP level |
NCT01661764 | Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention | colorectal adenoma | Oleic Acid (NPC261831) | NP level |
NCT00001696 | A Pharmacokinetic Study of Genistein, a Tyrosine Kinase Inhibitor | cancer | Genistein (NPC39426) | NP level |
NCT04359823 | DSAP Treatment Comparison | porokeratosis | Cholesterol (NPC28657) | NP level |
NCT01845727 | Topical 3% Amphotericin B Cream for the Treatment of Cutaneous Leishmaniasis in Colombia | cutaneous Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00263315 | Inhalation of Liposomal Amphotericin B to Prevent Invasive Aspergillosis | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT01437020 | SCH708980 With and Without AmBisome for Visceral Leishmaniasis | Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT01857479 | A Randomized Controlled Trial of Inhaled Amphotericin B for Maintaining Remission in Allergic Bronchopulmonary Aspergillosis | allergic bronchopulmonary aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT00541710 | Effect of Genistein in Women With Metabolic Syndrome | metabolic syndrome | Genistein (NPC39426) | NP level |
NCT04482595 | BIO 300 Oral Suspension in Previously Hospitalized Long COVID Patients | pulmonary fibrosis;severe acute respiratory syndrome | Genistein (NPC39426) | NP level |
NCT00418951 | Liposomal Amphotericin B (Ambisome) Versus Oral Voriconazole for the Prevention of Invasive Fungal Infections | acute myeloid leukemia;myelodysplastic syndrome | Amphotericin B (NPC67917) | NP level |
NCT00546039 | Synthetic Genistein (BONISTEIN™) in Patients Who Are Undergoing Surgery for Prostate Cancer | prostate adenocarcinoma | Genistein (NPC39426) | NP level |
NCT00216346 | Safety and Efficacy Study of Paromomycin to Treat Visceral Leishmaniasis | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00008359 | Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment | cancer | Amphotericin B (NPC67917) | NP level |
NCT00002316 | The Safety and Effectiveness of RMP-7 Plus Amphotericin B in Patients With HIV and Cryptococcal Meningitis | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT00376948 | Genistein, Gemcitabine, and Erlotinib in Treating Patients With Locally Advanced or Metastatic Pancreatic Cancer | pancreatic carcinoma | Genistein (NPC39426) | NP level |
NCT01792310 | A Phase 1/2A Study of LAM561 in Adult Patients With Advanced Solid Tumours | glioma | Oleic Acid (NPC261831) | NP level |
NCT00012467 | Safety and Antifungal Activity of Recombinant Interferon-Gamma 1b (rIFN-Gamma 1b) Given With Standard Therapy in Patients With Cryptococcal Meningitis | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT00003031 | Comparison of Voriconazole and Amphotericin B in Treating Patients With Aspergillosis | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT02656797 | Topical Liposomal Amphotericin B Gel Treatment for Cutaneous Leishmaniasis | Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00002742 | Antifungal Therapy for Fever and Neutropenia in Patients Receiving Treatment for Hematologic Cancer | chronic myeloproliferative disorder;leukemia;multiple myeloma;myelodysplastic syndrome;infection | Amphotericin B (NPC67917) | NP level |
NCT00204932 | Effects of CLA Supplements on Body Weight and Fat Oxidation | obesity | Linoleic Acid (NPC85813) | NP level |
NCT00451711 | Intermittent Liposomal Amphotericin B Primary Prophylaxis | acute myeloid leukemia | Amphotericin B (NPC67917) | NP level |
NCT00696969 | Safety and Efficacy Study to Evaluate Different Combination Treatment Regimens for Visceral Leishmaniasis | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00118040 | Phase II Study of Isoflavone G-2535 (Genistein) in Patients With Bladder Cancer | urinary bladder carcinoma | Genistein (NPC39426) | NP level |
NCT00002159 | A Randomized, Open, Comparative Multicenter Study of Initial Treatment With Intravenous Itraconazole Versus Amphotericin B Followed by Consolidation Treatment With Itraconazole Capsules in Patients With Blastomycosis or Histoplasmosis | blastomycosis;histoplasmosis | Amphotericin B (NPC67917) | NP level |
NCT00628719 | Single Infusion of Liposomal Amphotericin B in Indian Visceral Leishmaniasis | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT01945281 | Safety, Tolerability, and Efficacy of Caspofungin Versus Amphotericin B Deoxycholate in the Treatment of Invasive Candidiasis in Neonates and Infants (MK-0991-064) | Candidiasis, Invasive | Amphotericin B (NPC67917) | NP level |
NCT00467883 | Pilot Study of High Dose Liposomal Amphotericin B Efficacy in Initial Zygomycosis Treatment | mucormycosis | Amphotericin B (NPC67917) | NP level |
NCT00908791 | Proof of Principle Trial to Determine if Nutritional Supplement Conjugated Linoleic Acid (CLA) Can Modulate the Lipogenic Pathway in Breast Cancer Tissue | breast cancer | Linoleic Acid (NPC85813) | NP level |
NCT00497601 | A Phase II Study To Assess Safety and Efficacy Of Short-Course Regimens Of Amphotericin B Emulsion In Kala-Azar | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT02063802 | Metformin vs Conjugated Linoleic Acid and an Intervention Program With Healthy Habits in Obese Children | obesity | Linoleic Acid (NPC85813) | NP level |
NCT00607945 | Dietary Fatty Acids as Complementary Therapy in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Linoleic Acid (NPC85813) | NP level |
NCT00003315 | Liposomal Amphotericin B With or Without Sargramostim in Treating Patients With Invasive Fungal Infection | infection | Amphotericin B (NPC67917) | NP level |
NCT00001017 | Comparison of Fluconazole and Amphotericin B in the Treatment of Brain Infections in Patients With AIDS | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT00419770 | The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) Study | mucormycosis | Amphotericin B (NPC67917) | NP level |
NCT03945448 | Single Dose Liposomal Amphotericin for Asymptomatic Cryptococcal Antigenemia | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT00235651 | Abelcet Radiotagging Protocol: Inhaled Lipid Complex Abelcet® in Lung Transplant Recipients | lung disease | Amphotericin B (NPC67917) | NP level |
NCT00290758 | Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer | breast cancer | Genistein (NPC39426) | NP level |
NCT00287690 | Isoflavones and the Coronary Circulation in Men and Women With Coronary Artery Disease | coronary artery disease | Genistein (NPC39426) | NP level |
NCT00158730 | Study Safety/Efficacy of AmBisome Loading Dose Regimen Versus Standard AmBisome Regimen for Initial Treatment | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT01664650 | Effects of Genistein in Postmenopausal Women With Metabolic Syndrome | metabolic syndrome | Genistein (NPC39426) | NP level |
NCT00177710 | Pharmacokinetic Profile of Inhaled Liposomal Amphotericin B in Lung Transplant Recipients - Ambisome Study | fungal infectious disease | Amphotericin B (NPC67917) | NP level |
NCT00076869 | MK0991 in Combination With Standard Antifungal Agent(s) for the Treatment of Salvage Invasive Aspergillosis (0991-037) | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT00638196 | Placebo vs. Linoleic Acid Controlled Assessment of Treatment Efficacy in MS | multiple sclerosis | Oleic Acid (NPC261831) | NP level |
NCT01067443 | Clinical Trial to Assess the Safety and Efficacy of Sodium Stibogluconate (SSG) and AmBisome® Combination, Miltefosine and AmBisome® and Miltefosine Alone for the Treatment Visceral Leishmaniasis in Eastern Africa | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00002277 | A Comparison of Fluconazole and Amphotericin B in the Treatment of Fungal Infections | fungal infectious disease | Amphotericin B (NPC67917) | NP level |
NCT00244933 | Gemcitabine Hydrochloride and Genistein in Treating Women With Stage IV Breast Cancer | breast cancer | Genistein (NPC39426) | NP level |
NCT00965068 | Cholesterol in ASD: Characterization and Treatment | Asperger syndrome;autism | Cholesterol (NPC28657) | NP level |
NCT00029679 | Borage Oil and Ginkgo Biloba (EGb 761) in Asthma | asthma | Linoleic Acid (NPC85813) | NP level |
NCT00936910 | Antifungal Locks to Treat Fungal-related Central Line Infections | fungal infectious disease | Amphotericin B (NPC67917) | NP level |
NCT00371995 | Short Course of Miltefosine and Liposomal Amphotericin B for Kala-azar | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00009841 | Gene Therapy in Treating Patients With Advanced Head and Neck Cancer | head and neck malignant neoplasia | Cholesterol (NPC28657) | NP level |
NCT00106288 | Micafungin Versus AmBisome in Invasive Candidiasis and Candidemia | candidiasis | Amphotericin B (NPC67917) | NP level |
NCT00847678 | Efficacy and Safety of Mycograb as Adjunctive Therapy for Cryptococcal Meningitis in Patients With AIDS | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT00584532 | Effects of a Genistein Concentrated Polysaccharide (GCP) for Prostate Cancer on Active Surveillance. | prostate cancer | Genistein (NPC39426) | NP level |
NCT02766478 | Genistein Supplementation to Mitigate Cardiometabolic Dysfunction in Patients Undergoing Androgen Deprivation Therapy for Prostate Cancer | prostate cancer | Genistein (NPC39426) | NP level |
NCT00016744 | Phenylbutyrate/Genistein Duotherapy in Delta F508-Homozygous(for Cystic Fibrosis) | cystic fibrosis | Genistein (NPC39426) | NP level |
NCT04799236 | Treatment of Mucosal Bolivian Leishmaniasis | mucocutaneous Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00001107 | Comparison of Two Treatments to Prevent Invasive Fungal Infections in Patients Who Have Received Liver Transplants | candidiasis | Amphotericin B (NPC67917) | NP level |
NCT01126879 | Genistein in Treating Patients With Prostate Cancer | prostate adenocarcinoma | Genistein (NPC39426) | NP level |
NCT01985763 | Genistein in Treatment of Metastatic Colorectal Cancer | colorectal carcinoma;malignant colon neoplasm;rectum cancer | Genistein (NPC39426) | NP level |
NCT04031833 | Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial (EnACT) | cryptococcal meningitis | Amphotericin B (NPC67917) | NP level |
NCT00058266 | Genistein in Treating Patients With Localized Prostate Cancer Who Are Planning to Undergo Radical Prostatectomy | prostate cancer | Genistein (NPC39426) | NP level |
NCT01122771 | Phase III, Study of Three Short Course Combo (Ambisome®, Miltefosine, Paromomycin) Compared With AmBisome for the Treatment of VL in Bangladesh | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT04502381 | Combined Inhalational With Intravenous Amphotericin B Versus Intravenous Amphotericin B Alone for Pulmonary Mucormycosis | mucormycosis | Amphotericin B (NPC67917) | NP level |
NCT00047827 | Trial of Micafungin (FK463) in Combination With Liposomal Amphotericin B (AmBisome) for Aspergillosis | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT00177684 | Pharmacokinetic Profiles of Inhaled Lipid Complex Amphotericin B (Abelcet ®) | fungal infectious disease | Amphotericin B (NPC67917) | NP level |
NCT00370825 | Combination Chemotherapy for the Treatment of Indian Kala-Azar | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT01628471 | MTD Determination, Safety and Efficacy of the Decitabine-Genistein Drug Combination in Advanced Solid Tumors and Non-Small Cell Lung Cancer | non-small cell lung carcinoma | Genistein (NPC39426) | NP level |
NCT00882765 | Genistein in Treating Patients With Pancreatic Cancer That Can Be Removed by Surgery | pancreatic carcinoma | Genistein (NPC39426) | NP level |
NCT01566552 | Single Dose Liposomal Amphotericin B for Visceral Leishmaniasis | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT01325311 | Cholecalciferol and Genistein Before Surgery in Treating Patients With Early Stage Prostate Cancer | prostate adenocarcinoma | Genistein (NPC39426) | NP level |
NCT00334412 | COMBISTRAT: AmBisome® in Combination With Caspofungin for the Treatment of Invasive Aspergillosis | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT01489813 | Study of Genistein in Reducing Side Effects of Superficial Bladder Cancer Treatment | urinary bladder cancer | Genistein (NPC39426) | NP level |
NCT00951158 | A Molecular Pharmacodynamic Dose-titration Trial of Conjugated Linoleic Acid (CLA; Clarinol®) in Patients With Advanced Solid Tumors | neoplasm | Linoleic Acid (NPC85813) | NP level |
NCT00163111 | A Clinical Study Intended To Compare Treatment With Voriconazole To Treatment With Amphotericin Followed By Fluconazole In Patients With Candidemia, A Serious Fungus Infection Of The Blood. | candidiasis | Amphotericin B (NPC67917) | NP level |
NCT04018417 | Evaluation of Amphotericin B in Optisol-GS for Prevention of Post-Keratoplasty Fungal Infections. | Fuchs endothelial corneal dystrophy | Amphotericin B (NPC67917) | NP level |
NCT01058174 | Liver Transplant European Study Into the Prevention of Fungal Infection | fungal infectious disease | Amphotericin B (NPC67917) | NP level |
NCT03196921 | Efficacy and Safety of Oral Encochleated Amphotericin B for the Treatment of Cryptococcal Infection | infection | Amphotericin B (NPC67917) | NP level |
NCT00624143 | Antifungal Prophylaxis in Pediatric Acute Leukemia | leukemia | Amphotericin B (NPC67917) | NP level |
NCT00003938 | Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients | cancer | Amphotericin B (NPC67917) | NP level |
NCT01032187 | Amphotericin B to Treat Visceral Leishmaniasis in Brazilian Children | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
NCT00010686 | Dietary Phytoestrogens and Bone Metabolism | osteoporosis | Daidzein (NPC234560);Genistein (NPC39426) | NP level |
NCT00001646 | Voriconazole vs. Amphotericin B in the Treatment of Invasive Aspergillosis | aspergillosis | Amphotericin B (NPC67917) | NP level |
NCT02011958 | Efficacy Trial of Ambisome Given Alone and Ambisome Given in Combination With Miltefosine for the Treatment of VL HIV Positive Ethiopian Patients. | visceral Leishmaniasis | Amphotericin B (NPC67917) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
ESR1,ESR2,AKR1C3,AOX1,MAOB
NCT00584532,NCT00005827,NCT00058266,NCT02766478 |
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
ESR2,EGFR,CA12,CYP19A1,ESR1,CA4
NCT00244933,NCT00290758,NCT00908791 |
Meningitis due to Cryptococcus neoformansDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D01.10 |
NCT00002316,NCT04031833,NCT00000776,NCT00012467,NCT00001017,NCT02686853,NCT03945448,NCT00847678,NCT00145249
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
FABP5,FFAR4,CYP19A1,CYP2C9,FABP5,TSHR,F2,FFAR4,OR51E2
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CA12,DPP4,LMNA,FABP5,AOX1,TSHR,PTGS2,BLM,CYP19A1
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
CA12,DPP4,CA4,FABP5,F2,ESRRA,BLM,FABP3,CYP2C9
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
CA12,CA4,FABP5,FABP4,BLM,FABP3,CYP19A1,OR51E2
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CA12,AKR1C3,TSHR,F2,BLM,CA7,OR51E2,CYP2C9
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
CA12,AKR1C3,TSHR,F2,NR1I2,BLM,CA7,CYP2C9
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
LMNA,CA4,FABP5,BLM,MAPT,OR51E2,ESR2
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
DPP4,FABP5,FFAR4,MAPT,ALOX15,CYP2C9,ESRRB
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
PPARA,PTGS2,DPP4,FFAR1,F2
NCT00607945 |
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
CA4,ESRRB,ESRRA,F2,PTGS2
NCT00029679 |
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
FABP5,ALOX15,OR51E2
NCT00546039,NCT01126879,NCT01325311 |
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
CA4,RORC,FABP5,BLM,MAPT,OR51E2
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
DPP4,LMNA,CA4,PTGS2,FABP3,ESRRB
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
DPP4,AOX1,FFAR4,ESR1,OR51E2,ESRRB
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
ESRRA,ESRRB,RORC,DPP4
FABP5 |
Skin fungal infection disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA60 |
NCT00177684,NCT01058174,NCT00002277,NCT00936910,NCT00177710
|
CandidosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F23 |
NCT00001107,NCT00163111,NCT00815516,NCT01945281,NCT00106288
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
F2,BLM,ALOX15,CYP2C9,ESRRB
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA,EGFR,FFAR1,CYP19A1,ESRRB
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
PTGS2,MAPT,MAOB,ESR2
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
F2,RORC,ESR1
NCT00638196 |
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PTGS2,ESR1,ESR2,PPARA
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
MAPT
NCT00451711,NCT00418951,NCT03187691 |
MucormycosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F2C |
NCT00467883,NCT00419770,NCT04502381,NCT05468372
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
F2,BLM,ALOX15,CYP19A1
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
AKR1C3,F2,PTGS2,FABP4
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
CA4,RORC,F2,ESRRB
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ALOX15,CYP2C9,ESR2,ESRRB
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CA12,DPP4,CA7,FFAR1
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
ESR1,DPP4,PPARA
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA4,CYP2C9,CA12
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
PTGS2,ESRRB,ESRRA
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
EGFR
NCT00002742,NCT00418951 |
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
PPARA,F2,PTGS2
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
PTGS2,ESR1,CYP19A1
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
PTGS2,ESRRA,ESRRB
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
PTGS2,ESR1,AKR1C3
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
F2,PTGS2,DPP4
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
FFAR1,DPP4,PPARA
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
PTGS2,MAOB,MAPT
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ESR2,ESRRB,ESRRA
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4
NCT01664650,NCT00541710 |
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
EGFR
NCT01628471,NCT02567799 |
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
EGFR
NCT01661764,NCT01985763 |
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00003938,NCT00001696,NCT00008359
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT00003315,NCT03196921,NCT00002742
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
DPP4,PTGS2,CYP19A1
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NR1I2,FABP3,FFAR1
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
CA12,ESR1,BLM
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
DPP4,TSHR,BLM
NCT01032187,NCT04799236,NCT00876824,NCT03636659,NCT02656797,NCT00696969,NCT00497601,NCT00371995,NCT00523965,NCT02025491,NCT01067443,NCT00628719,NCT01437020,NCT01310738,NCT00832208,NCT01845727,NCT00370825,NCT01122771,NCT02011958,NCT00216346,NCT01566552 |
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
PTGS2,EGFR
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
CYP19A1,ESR2
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
ESR1,EGFR
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
PTGS2,MAOB
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
RORC
PTGS2 |
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR1,ESR2
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR,ESR2
|
Eyelid inflammatory disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A02 |
ESRRA,ESRRB
|
Contact dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK00-EK0Z |
ESRRA,ESRRB
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
ESR2,PTGS2
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
EGFR,RORC
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
ESRRB,ESRRA
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA12,CA4
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ESRRA,PTGS2
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
PPARA
FABP4 |
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
F2,EGFR
|
Skin diseaseDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA00-EM0Z |
ESRRA,ESRRB
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
EGFR
NCT00009841 |
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4
NCT00965068 |
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT00882765,NCT00376948
|
Vaginal dischargeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF3A |
NCT01293643,NCT01293643
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
NCT00204932,NCT02063802
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT00016744,NCT00590538
|
LeukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2B33 |
NCT00002742,NCT00624143
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
CYP2C9,TSHR
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
FABP4,PTGS2
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CA12,AKR1C3
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
BLM,ALOX15
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
BLM,CYP2C9
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
FFAR1,ESRRB
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
FFAR1,PTGS2
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CA12,ESRRA
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
AKR1C3,BLM
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
EGFR,TSHR,BLM,OR51E2,CA12,LMNA,TDP1,NR1I2,FABP3,ESR2,PPARA,MAOB,FABP5,AOX1,FFAR1,FABP4
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
TSHR,FFAR4,ESRRB,TDP1,NR1I2,CA7,DPP4,RORC,ALOX15,CYP19A1,FABP5,ESRRA,PTGS2,FFAR1
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
DPP4,LMNA,AKR1C3,MAOB,F2,PTGS2,FFAR4,NR1I2,BLM,FABP3,CA7,ALOX15,OR51E2,CYP2C9
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
CA12,CA4,FABP5,AKR1C3,FABP4,BLM,MAPT,CYP19A1,OR51E2,CA12,CYP19A1,MAPT,AKR1C3
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CA12,TDP1,RORC,FABP5,TSHR,ESRRA,FFAR4,ESR1,NR1I2,FABP3,ALOX15,ESRRB
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CA12,DPP4,LMNA,TDP1,EGFR,AOX1,FFAR1,FFAR4,CA7,ALOX15,OR51E2
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
CA4,EGFR,ESR1,ESRRA,ESRRB,PTGS2,RORC,PPARA,CA12,AOX1
|
AspergillosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F20 |
NCT03327727,NCT00003031,NCT04267497,NCT00158730,NCT00047827,NCT00076869,NCT00263315,NCT00334412,NCT00001646,NCT00986713
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
CA12,DPP4,CA4,FABP5,BLM,FABP3,CA7,FFAR1,CYP19A1,OR51E2
|
Skin tag/polypDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK71 |
MAOB
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
PTGS2
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
MAOB
|
Joint painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME82 |
PTGS2
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
MAPT
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
EGFR
|
Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F2
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
TSHR
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
ESR2
|
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
FFAR1
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
F2
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
CA4
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
EGFR
|
Inherited coagulation factor deficiencyDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B14 |
PTGS2
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
PTGS2
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
PTGS2
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
DPP4
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
MAPT
|
Skin cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30-2C37 |
MAOB
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
EGFR
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
EGFR
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
EGFR
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1
|
Autoimmune diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40-4A45 |
RORC
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
PPARA
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
EGFR
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
ESR2
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
PTGS2
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
MAOB
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
EGFR
|
Knee osteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
PTGS2
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
PPARA
|
Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F2
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
MAOB
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
MAOB
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
MAOB
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
MAOB
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
EGFR
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
F2
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
EGFR
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
CYP19A1
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
MAOB
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ESR1
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
PPARA
|
Urinary system diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC2Z |
PTGS2
|
Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F2
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
DPP4
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
Inflammatory spondyloarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA92 |
PTGS2
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Vitamin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55-5B5F |
AOX1
|
Otitis mediaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA80-AB0Z |
PTGS2
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
MAOB
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
ESR1
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
ESRRA
|
Reactive arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA11 |
PTGS2
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
F2
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
EGFR
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
EGFR
|
Primary psychotic disorder manifestationDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A25 |
MAOB
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
EGFR
|
Spinal painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84 |
PTGS2
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
DyslipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80-5C81 |
PPARA
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
TSHR
|
Degenerative high myopiaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B76 |
ESRRA
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
EGFR
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
F2
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
F2
|
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04482595
|
PorokeratosesDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED52 |
NCT04359823
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
NCT00002742
|
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT01489813
|
BlastomycosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F22 |
NCT00002159
|
Chronic mucocutaneous candidosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F23.14 |
NCT02629419
|
Aspergillus-induced allergic or hypersensitivity conditionsDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA82.4 |
NCT01857479
|
Disorders of cholesterol synthesisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52.10 |
NCT00272844
|
Myeloproliferative neoplasm, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH5HH7 |
NCT00002742
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
NCT04482595
|
Endothelial corneal dystrophyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A70.0 |
NCT04018417
|
OsteoporosisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83.1 |
NCT00010686
|
Other specified increased intracranial pressureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D60.Y |
NCT00000776
|
Precursor cell lymphoblastic leukaemia, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH5J37 |
NCT03187691
|
Glioma, malignantDisease Category: X.Extension CodesDisease ICD-11 Code: XH4RQ3 |
NCT01792310
|
HistoplasmosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F2A |
NCT00002159
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT01985763
|
Autism spectrum disorder without disorder of intellectual development and with mild or no impairment of functional languageDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02.0 |
NCT00965068
|
Neoplasms of unknown behaviour of urinary organsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F98 |
NCT00118040
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT00951158
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT00287690
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT00235651
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT01985763
|
Non-alcoholic steatohepatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92.1 |
PTGS2
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
TSHR
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
NR1I2
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
CA4
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
CA4
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
F2
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
DPP4
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
FABP4
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
FABP4
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FFAR4
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
PTGS2
|
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
FABP4
|