Collective Molecular Activities of the Plant: Citrus Wilsonii
Plant ID: NPO16308
Plant Latin Name: Citrus Wilsonii
Taxonomy Genus: Citrus
Taxonomy Family: Rutaceae
Plant External Links:
NCBI TaxonomyDB:
475932
Plant-of-the-World-Online:
n.a.
Country/Region:
ChinaTraditional Medicine System:
TCMChina
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
149 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
83 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
54 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC96286
Ingredient ID: NPC95582
Ingredient ID: NPC93433
Ingredient ID: NPC89088
Ingredient ID: NPC88445
Ingredient ID: NPC87136
Ingredient ID: NPC85233
Ingredient ID: NPC84793
Ingredient ID: NPC80170
Ingredient ID: NPC79056
Ingredient ID: NPC78679
Ingredient ID: NPC75110
Ingredient ID: NPC74539
Ingredient ID: NPC725
Ingredient ID: NPC70741
Ingredient ID: NPC65003
Ingredient ID: NPC5893
Ingredient ID: NPC55147
Ingredient ID: NPC54341
Ingredient ID: NPC52005
Ingredient ID: NPC51986
Ingredient ID: NPC51843
Ingredient ID: NPC49905
Ingredient ID: NPC4917
Ingredient ID: NPC44328
Ingredient ID: NPC43587
Ingredient ID: NPC42760
Ingredient ID: NPC41004
Ingredient ID: NPC40818
Ingredient ID: NPC35627
Ingredient ID: NPC33461
Ingredient ID: NPC324108
Ingredient ID: NPC319817
Ingredient ID: NPC31251
Ingredient ID: NPC310350
Ingredient ID: NPC309284
Ingredient ID: NPC308936
Ingredient ID: NPC307732
Ingredient ID: NPC306397
Ingredient ID: NPC305945
Ingredient ID: NPC305016
Ingredient ID: NPC304934
Ingredient ID: NPC303644
Ingredient ID: NPC303210
Ingredient ID: NPC302950
Ingredient ID: NPC302556
Ingredient ID: NPC298796
Ingredient ID: NPC296020
Ingredient ID: NPC294409
Ingredient ID: NPC291124
Ingredient ID: NPC289758
Ingredient ID: NPC287349
Ingredient ID: NPC286626
Ingredient ID: NPC28169
Ingredient ID: NPC279985
Ingredient ID: NPC278525
Ingredient ID: NPC277400
Ingredient ID: NPC271270
Ingredient ID: NPC268572
Ingredient ID: NPC26795
Ingredient ID: NPC26635
Ingredient ID: NPC265800
Ingredient ID: NPC263265
Ingredient ID: NPC261657
Ingredient ID: NPC25979
Ingredient ID: NPC25810
Ingredient ID: NPC255648
Ingredient ID: NPC251762
Ingredient ID: NPC251179
Ingredient ID: NPC250828
Ingredient ID: NPC248680
Ingredient ID: NPC247553
Ingredient ID: NPC246469
Ingredient ID: NPC243728
Ingredient ID: NPC243509
Ingredient ID: NPC240722
Ingredient ID: NPC239556
Ingredient ID: NPC239270
Ingredient ID: NPC237155
Ingredient ID: NPC236726
Ingredient ID: NPC233169
Ingredient ID: NPC231773
Ingredient ID: NPC23070
Ingredient ID: NPC230301
Ingredient ID: NPC223695
Ingredient ID: NPC221124
Ingredient ID: NPC216083
Ingredient ID: NPC213472
Ingredient ID: NPC213054
Ingredient ID: NPC213
Ingredient ID: NPC211960
Ingredient ID: NPC209296
Ingredient ID: NPC207594
Ingredient ID: NPC206760
Ingredient ID: NPC206655
Ingredient ID: NPC205441
Ingredient ID: NPC204607
Ingredient ID: NPC203784
Ingredient ID: NPC201075
Ingredient ID: NPC198743
Ingredient ID: NPC19560
Ingredient ID: NPC194426
Ingredient ID: NPC191567
Ingredient ID: NPC190270
Ingredient ID: NPC189470
Ingredient ID: NPC185411
Ingredient ID: NPC183936
Ingredient ID: NPC183923
Ingredient ID: NPC18351
Ingredient ID: NPC182267
Ingredient ID: NPC180006
Ingredient ID: NPC178501
Ingredient ID: NPC177771
Ingredient ID: NPC177731
Ingredient ID: NPC176740
Ingredient ID: NPC172746
Ingredient ID: NPC168409
Ingredient ID: NPC162822
Ingredient ID: NPC162117
Ingredient ID: NPC157432
Ingredient ID: NPC1573
Ingredient ID: NPC154409
Ingredient ID: NPC152538
Ingredient ID: NPC149006
Ingredient ID: NPC148709
Ingredient ID: NPC147086
Ingredient ID: NPC145708
Ingredient ID: NPC142860
Ingredient ID: NPC142753
Ingredient ID: NPC141078
Ingredient ID: NPC137816
Ingredient ID: NPC133667
Ingredient ID: NPC131482
Ingredient ID: NPC131157
Ingredient ID: NPC129999
Ingredient ID: NPC129257
Ingredient ID: NPC124830
Ingredient ID: NPC120785
Ingredient ID: NPC114577
Ingredient ID: NPC113961
Ingredient ID: NPC113098
Ingredient ID: NPC112575
Ingredient ID: NPC107525
Ingredient ID: NPC107014
Ingredient ID: NPC105095
Ingredient ID: NPC104338
Ingredient ID: NPC10286
Ingredient ID: NPC10285
Ingredient ID: NPC102091
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
| Cytochrome P450 | Cytochrome P450 family 2 | CYP2C9 | Cytochrome P450 2C9 | P11712 | CHEMBL3397 |
| Therapeutic Target | Enzyme | BLM | Bloom syndrome protein | P54132 | CHEMBL1293237 |
| Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
| Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
| Therapeutic Target | Lyase | CA4 | Carbonic anhydrase IV | P22748 | CHEMBL3729 |
| Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
| Therapeutic Target | Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
| Therapeutic Target | Methyl-lysine/arginine binding protein | SMN1 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
| Therapeutic Target | Methyl-lysine/arginine binding protein | L3MBTL1 | Lethal(3)malignant brain tumor-like protein 1 | Q9Y468 | CHEMBL1287622 |
| Therapeutic Target | Nuclear hormone receptor subfamily 1 | THRB | Thyroid hormone receptor beta-1 | P10828 | CHEMBL1947 |
| Therapeutic Target | Oxidoreductase | ALDH2 | Aldehyde dehydrogenase | P05091 | CHEMBL1935 |
| Therapeutic Target | Serine protease | DPP4 | Dipeptidyl peptidase IV | P27487 | CHEMBL284 |
| Therapeutic Target | Transcription factor | HIF1A | Hypoxia-inducible factor 1 alpha | Q16665 | CHEMBL4261 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 108 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT02213094 | Phase I Study of Nicotinamide for Early Onset Preeclampsia | preeclampsia | Niacinamide (NPC306397) | NP level |
| NCT02325583 | Intraoral 30% Glucose Effect In Newborns | epilepsy | Glucose, Liquid (NPC289758) | NP level |
| NCT01223690 | Clarithromycin as Immunomodulator for the Management of Sepsis | Sepsis;septic shock | Glucose, Liquid (NPC289758) | NP level |
| NCT00552786 | Antioxidation Medication for Noise-induced Hearing Loss | hearing loss | Glucose, Liquid (NPC289758) | NP level |
| NCT00533195 | Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis | atopic eczema | Bergapten (NPC74539) | NP level |
| NCT02258074 | The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE | chronic kidney disease | Niacinamide (NPC306397) | NP level |
| NCT00639808 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
| NCT02596477 | Evaluation of Vepoloxamer in Chronic Heart Failure | heart failure | Glucose, Liquid (NPC289758) | NP level |
| NCT04133922 | Effect of GLP-1 on Microvascular Insulin Responses in Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT02319512 | Effects of Chewing Gum Against Postoperative Ileus | ileus | Glucose, Liquid (NPC289758) | NP level |
| NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients | prostate cancer | Rutin (NPC176740) | NP level |
| NCT01210183 | Biological Response of Stage IV Knee Osteoarthritis to Serial 12.5% Dextrose | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
| NCT00835939 | Treatment for Achilles Tendinopathy | Tendinopathy | Glucose, Liquid (NPC289758) | NP level |
| NCT00617552 | Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery | ileus | Glucose, Liquid (NPC289758) | NP level |
| NCT03205553 | Direct Peritoneal Resuscitation in Gastroschisis | gastroschisis | Glucose, Liquid (NPC289758) | NP level |
| NCT01110512 | Comparative Efficacy of Two Preparations of the Association Diosmin (450 mg) + Hesperidin (50 mg) in the Treatment of Chronic Venous Insufficiency (CVI) | venous insufficiency | Diosmin (NPC209296) | NP level |
| NCT02632630 | Nutrition Supplementation in Hospitalized Patients | malnutrition | Glucose, Liquid (NPC289758) | NP level |
| NCT02910518 | A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT04649203 | Cytoflavin in the Treatment of Patients With Diabetic Polyneuropathy | diabetic neuropathy | Niacinamide (NPC306397) | NP level |
| NCT04726436 | Dextrose Effect on Postoperative Nausea and Vomiting (PONV) | post operative nausea and vomiting | Glucose, Liquid (NPC289758) | NP level |
| NCT04088591 | High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda | Sepsis | Glucose, Liquid (NPC289758) | NP level |
| NCT01557296 | Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
| NCT02710266 | Evaluation of the Effect of Gabexate Mesilate in the Hepatocyte Protection After Liver Resection | liver disease | Glucose, Liquid (NPC289758) | NP level |
| NCT00508885 | The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients | Hyperphosphatemia | Niacinamide (NPC306397) | NP level |
| NCT03769285 | Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial | basal cell carcinoma;squamous cell carcinoma | Niacinamide (NPC306397) | NP level |
| NCT01381354 | Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) | multiple sclerosis | Niacinamide (NPC306397) | NP level |
| NCT00337597 | Continuous Regional Analgesia After Total Knee Arthroplasty | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT03690583 | Immunomodulation by Zinc Supplementation in Children With Pneumonia | pneumonia | Glucose, Liquid (NPC289758) | NP level |
| NCT00617981 | Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC) | hepatocellular carcinoma | Glucose, Liquid (NPC289758) | NP level |
| NCT00580931 | Safety Study of Nicotinamide to Treat Alzheimer's Disease | Alzheimer disease | Niacinamide (NPC306397) | NP level |
| NCT01307904 | The Glycemic Indices of Five Common Varieties of Dates in the Tested Among Healthy and Diabetic Subjects | diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT03418935 | Remaxol® in Mechanical Jaundice of Non-malignant Origin | obstructive jaundice | Niacinamide (NPC306397) | NP level |
| NCT04843553 | Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients | actinic keratosis | Niacinamide (NPC306397) | NP level |
| NCT01011699 | Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients | chronic kidney disease | Niacinamide (NPC306397) | NP level |
| NCT03626298 | Efficacy and Tolerability of Nicotinamide Plus Cream for Moderate Acne Vulgaris in Indonesia | acne | Niacinamide (NPC306397) | NP level |
| NCT00632775 | 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
| NCT03260166 | Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus | cutaneous lupus erythematosus;systemic lupus erythematosus | Niacinamide (NPC306397) | NP level |
| NCT03392623 | DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide. | freckles | Niacinamide (NPC306397) | NP level |
| NCT03024814 | Prophylactic Acetaminophen for Prevention Intraventricular Hemorrhage in Premature Infants | hemorrhage | Glucose, Liquid (NPC289758) | NP level |
| NCT01251770 | Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
| NCT03860688 | Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins | hyperlipidemia | Glucose, Liquid (NPC289758) | NP level |
| NCT01300260 | Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose | type 2 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT02140814 | Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease | Polycystic Kidney Disease | Niacinamide (NPC306397) | NP level |
| NCT03994471 | Efficacy and Safety of XyloCore Peritoneal Dialysis Solution. | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
| NCT02416739 | Anticancer Activity of Nicotinamide on Lung Cancer | non-small cell lung carcinoma | Niacinamide (NPC306397) | NP level |
| NCT00612014 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
| NCT04557878 | Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction | temporomandibular joint disorder | Glucose, Liquid (NPC289758) | NP level |
| NCT05185999 | Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
| NCT05205486 | Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults | infection | Glucose, Liquid (NPC289758) | NP level |
| NCT02591927 | Reappraisal of GIK in Acute STEMI by Pre-hospital Administration | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
| NCT00800085 | Beta Cell Function in (Pre) Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT04870866 | NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia | Ataxia-telangiectasia | Niacinamide (NPC306397) | NP level |
| NCT01589809 | Effect of Nicotinamide in Friedreich's Ataxia | neurodegenerative disease | Niacinamide (NPC306397) | NP level |
| NCT03761511 | Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia | Friedreich ataxia | Niacinamide (NPC306397) | NP level |
| NCT02185729 | Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunteers | metabolic disease | Glucose, Liquid (NPC289758) | NP level |
| NCT03357666 | Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis | bacterial vaginosis | Glucose, Liquid (NPC289758) | NP level |
| NCT02180412 | Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria | porphyria | Glucose, Liquid (NPC289758) | NP level |
| NCT02134249 | Diosmin Versus Cabergoline for Prevention of Ovarian Hyperstimulation Syndrome | infertility | Diosmin (NPC209296) | NP level |
| NCT01368887 | Study to Test the Effectiveness of a New Treatment for Scalp Psoriasis | psoriasis | Niacinamide (NPC306397) | NP level |
| NCT04055818 | A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease | sickle cell anemia | Niacinamide (NPC306397) | NP level |
| NCT00691210 | Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies | Hodgkins lymphoma;non-Hodgkins lymphoma | Niacinamide (NPC306397) | NP level |
| NCT02678208 | The Effect of Tranexamic Acid on Uterine Blood Flow After Vaginal Delivery | postpartum hemorrhage | Glucose, Liquid (NPC289758) | NP level |
| NCT02374281 | Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT01075984 | Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for Invasive Fungal Infections (P05520) | fungal infectious disease | Glucose, Liquid (NPC289758) | NP level |
| NCT00091507 | IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium. | congestive heart failure;intermediate coronary syndrome;myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
| NCT04844528 | Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia (CLL) With History of Non-melanoma Skin Cancers (NMSC) | chronic lymphocytic leukemia | Niacinamide (NPC306397) | NP level |
| NCT00316472 | The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients | Hyperphosphatemia | Niacinamide (NPC306397) | NP level |
| NCT04918719 | Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke | Ischemic stroke | Glucose, Liquid (NPC289758) | NP level |
| NCT02728037 | Magnesium-Based Trigger Point Injections for Relief of Chronic Myofascial Pelvic Pain | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT04409665 | The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST) | respiratory failure | Glucose, Liquid (NPC289758) | NP level |
| NCT02558595 | Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2) | Polycystic Kidney Disease | Niacinamide (NPC306397) | NP level |
| NCT01547364 | Caudal Epidural Injection of Dextrose For Low Back Pain | Low back pain | Glucose, Liquid (NPC289758) | NP level |
| NCT01883440 | Glucose Oxidase as Treatment Against Common Cold | common cold | Glucose, Liquid (NPC289758) | NP level |
| NCT01753882 | Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI) | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
| NCT04670081 | Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression | depressive disorder | Niacinamide (NPC306397) | NP level |
| NCT00033436 | Radiation Therapy With or Without Carbogen and Niacinamide in Treating Patients With Bladder Cancer | urinary bladder cancer | Niacinamide (NPC306397) | NP level |
| NCT04001036 | Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
| NCT05029037 | High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. | COVID-19 | Glucose, Liquid (NPC289758) | NP level |
| NCT02752308 | Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair | hypospadias | Glucose, Liquid (NPC289758) | NP level |
| NCT02616731 | Oral Tranexamic Acid Versus Diosmin for Treatment of Menorrhagia in Women Using Copper IUD | Menorrhagia | Diosmin (NPC209296) | NP level |
| NCT03419364 | Study of Nicotinamide in Early Onset Preeclampsia | preeclampsia | Niacinamide (NPC306397) | NP level |
| NCT01909336 | Use of Isotonic Solutions Versus Hypotonic Solutions for Preventing Hospital Acquired Hyponatremia | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
| NCT05424315 | Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
| NCT03039673 | MIROCALS: Modifying Immune Response and OutComes in ALS | amyotrophic lateral sclerosis | Glucose, Liquid (NPC289758) | NP level |
| NCT01485315 | Transfusion-requirements in Septic Shock Trial | septic shock | Glucose, Liquid (NPC289758) | NP level |
| NCT04791202 | Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT01788969 | Serotonergic Modulation of Motor Function in Subacute and Chronic SCI | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
| NCT03241706 | Liver Glycogen and Hypoglycemia in Humans | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
| NCT01548612 | Add-on Sodium Nitroprusside to Treatment as Usual in Schizophrenia | schizophrenia | Glucose, Liquid (NPC289758) | NP level |
| NCT02269735 | A Three-part Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-2640 in Healthy Participants (Part I) and Participants With Type 1 Diabetes Mellitus (Parts II and III) (MK-2640-001) | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
| NCT03778593 | FOLFIRINOX for 2nd-line Treatment of BTC | biliary tract cancer | Glucose, Liquid (NPC289758) | NP level |
| NCT01121354 | Pharmacokinetics and Safety of Cefazolin 2g in DUPLEX | infection | Glucose, Liquid (NPC289758) | NP level |
| NCT00686608 | Hypothalamic Functional Magnetic Resonance Imaging (fMRI) Response to Nutrients | obesity | Glucose, Liquid (NPC289758) | NP level |
| NCT02866435 | Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
| NCT04895358 | Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49) | breast neoplasm | Glucose, Liquid (NPC289758) | NP level |
| NCT04677829 | Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI) | brain injury | Glucose, Liquid (NPC289758) | NP level |
| NCT05160532 | Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
| NCT00823108 | Rapid Administration of Insulin in Sepsis | septic shock | Glucose, Liquid (NPC289758) | NP level |
| NCT03577730 | Caffeine and Neurologic Recovery Following Surgery and General Anesthesia | pain | Glucose, Liquid (NPC289758) | NP level |
| NCT04832009 | Reversing Glucose and Lipid-mediated Vascular Dysfunction | hypertension | Glucose, Liquid (NPC289758) | NP level |
| NCT02701127 | Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury | Acute kidney injury | Niacinamide (NPC306397) | NP level |
| NCT02054325 | Study Protocol Comparing Polidocanol Versus Hypertonic Glucose for Treatment of Reticular Veins | Varicose veins | Glucose, Liquid (NPC289758) | NP level |
| NCT00330096 | Effects of Hesperidin on Bone Mineral Density and Bone Metabolism of Postmenopausal Women | osteoporosis | Hesperidin (NPC79056) | NP level |
| NCT05326763 | Functional and Electromyographical Changes After PRP or Dextrose Injection in Chronic Lateral Epicondylitis | lateral epicondylitis | Glucose, Liquid (NPC289758) | NP level |
| NCT03337477 | A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 | Hyperkalemia | Glucose, Liquid (NPC289758) | NP level |
| NCT00213759 | Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSF | neutropenia | Glucose, Liquid (NPC289758) | NP level |
| NCT00062972 | Improving Memory in Patients With Multiple Sclerosis | multiple sclerosis | Glucose, Liquid (NPC289758) | NP level |
| NCT03268902 | Early Life Interventions for Childhood Growth and Development In Tanzania | malnutrition | Niacinamide (NPC306397) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
BLM,CA4,CA9,CYP19A1,CA12,L3MBTL1,CA12,CA9,CYP19A1
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
BLM,MAOB,SMN1,CA9,ACHE,CA12,THRB
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
BLM,CA7,CYP2C9,CA9,ACHE,CA12,F2
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
BLM,CA7,CA4,DPP4,CA9,CYP19A1,CA12
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ACHE
NCT02728037,NCT03577730,NCT04791202,NCT02374281,NCT00337597 |
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
CYP2C9,CA9,ACHE,CYP19A1,CA9,F2
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
BLM,CA7,CYP2C9,CA9,CA12,F2
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
CYP1B1,ALDH2,CYP2C9,DPP4,CA9,ACHE
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
BLM,CYP1B1,DPP4,CA9,CYP19A1,CA12
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
F2,DPP4
NCT02591927,NCT00091507,NCT05424315 |
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT04001036,NCT03994471,NCT02258074,NCT01011699,NCT05185999
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
BLM,CA4,HIF1A,CA9,L3MBTL1
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
BLM,CA4,CYP19A1,CA12,L3MBTL1
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CA7,SMN1,DPP4,CA9,CA12
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
BLM,CYP2C9,CA9,CYP1A1,F2
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA4,CA9,CA12,CYP19A1
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
CA9,CA12,CA4,HIF1A
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT02269735,NCT04133922,NCT02910518,NCT00800085
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
CA7,DPP4,CA9,CYP19A1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CYP1A2,CA9,CA12,THRB
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
BLM,CYP2C9,CYP1A2,CA9
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
THRB,CYP2C9,CYP1A1,ACHE
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CA12,CYP1B1,CA7,DPP4
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA12,CYP2C9,CA4
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
MAOB,ACHE
NCT00580931 |
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
MAOB,HIF1A
NCT04832009 |
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
F2,DPP4
NCT01300260 |
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
F2
NCT01381354,NCT00062972 |
GastroparesisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41.00 |
NCT00612014,NCT00639808,NCT01557296
|
Hypo-kalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C77 |
NCT01251770,NCT00632775,NCT01909336
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ACHE,CYP1A1
NCT03260166 |
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT01485315,NCT00823108,NCT01223690
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
CA4
NCT02213094,NCT03419364 |
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
BLM,CA4,ACHE
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
BLM,CYP19A1,F2
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
DPP4,CYP19A1,ACHE
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
CA9,CYP1A1,F2
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
CA4,DPP4,ACHE
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
BLM,CA9,CA12
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP1A2,CYP1A1,CA12
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ALDH2,ACHE
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
ALDH2,F2
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
MAOB,ACHE
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
ACHE,MAOB
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4
NCT02185729 |
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA12,CA4
|
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
SMN1,SMN2
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
DPP4
NCT01368887 |
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ACHE,CA4
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
F2,CA4
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
MAOB
NCT04726436 |
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
CA9,HIF1A
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
MAOB
NCT01705652 |
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
F2
NCT04918719 |
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
DPP4
NCT01307904 |
Injury of spinal cord, level unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51.2 |
NCT01788969,NCT01753882
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT01121354,NCT05205486
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT01210183,NCT05160532
|
Postoperative ileusDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA91-DB30 |
NCT02319512,NCT00617552
|
Disorders of calcium or phosphate excretionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB90.48 |
NCT00508885,NCT00316472
|
Autosomal dominant polycystic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB81 |
NCT02558595,NCT02140814
|
Hypoglycaemia without associated diabetesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A41 |
NCT03241706,NCT02866435
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT04088591,NCT01223690
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT03268902,NCT02632630
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
BLM,DPP4
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
CA9,F2
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
CA4,F2
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CA9,CA12
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
BLM,ACHE
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CA9,CYP1A1
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
HIF1A,CYP19A1
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
CYP1B1,DPP4
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
BLM,CYP1B1,CA7,MAOB,ALDH2,HIF1A,CYP2C9,DPP4,CA9,ACHE,F2
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
BLM,CA4,HIF1A,CYP2C9,SMN1,DPP4,ACHE,CA12,THRB,F2
|
Primary psychotic disorder manifestationDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A25 |
MAOB
|
Hypo-thyroidismDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A00 |
THRB
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
MAOB
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
F2
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
ALDH2
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
DPP4
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
DPP4
|
Skin cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30-2C37 |
MAOB
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
MAOB
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
CYP19A1
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
CYP19A1
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
MAOB
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
F2
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
F2
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
CYP19A1
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
MAOB
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE
|
Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F2
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
MAOB
|
Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F2
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
THRB
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
HIF1A
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
DPP4
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Adrenomedullary hyperfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A75 |
HIF1A
|
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
THRB
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
F2
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
F2
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
CA9
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F2
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
MAOB
|
Unspecific substance use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4Z |
ALDH2
|
Skin tag/polypDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK71 |
MAOB
|
PolyuriaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF55 |
NCT02180412
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00091507
|
GastroschisisDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB02 |
NCT03205553
|
Cutaneous lupus erythematosusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EB50-EB5Z |
NCT03260166
|
Temporomandibular joint disordersDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0E.8 |
NCT04557878
|
Squamous cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B60-2D01 |
NCT03769285
|
Unstable anginaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40.0 |
NCT00091507
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT00617981
|
Basal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C32 |
NCT03769285
|
Intracranial injury, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.Z |
NCT04677829
|
Low back painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84.2 |
NCT01547364
|
NeutropeniaDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B00 |
NCT00213759
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
NCT01548612
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
NCT03626298
|
Acute kidney failure, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60.Z |
NCT02701127
|
Neurodegenerative disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20-8A23 |
NCT01589809
|
Malignant lymphoma, not elsewhere classifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33.5 |
NCT00691210
|
Friedreich ataxiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03.10 |
NCT03761511
|
Chronic lymphocytic leukaemia or small lymphocytic lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82.0 |
NCT04844528
|
Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT03024814
|
Diabetic polyneuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C03.0 |
NCT04649203
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT03039673
|
Varicose veinsDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD74-BD75 |
NCT02054325
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB10Z |
NCT02710266
|
HyperkalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C76 |
NCT03337477
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
NCT00686608
|
Actinic keratosisDisease Category: X.Extension CodesDisease ICD-11 Code: XH36H6 |
NCT04843553
|
Respiratory failureDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB41 |
NCT04409665
|
Common cold disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SA60 |
NCT01883440
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
NCT03860688
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT05029037
|
Diseases of the musculoskeletal system or connective tissue, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FC0Z |
NCT00835939
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
NCT02678208
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NCT00533195
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
NCT02134249
|
DNA repair defects other than combined T-cell or B-cell immunodeficienciesDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01.31 |
NCT04870866
|
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT00033436
|
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT04055818
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT03690583
|
Vaginal dischargeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF3A |
NCT03357666
|
Heavy menstrual bleedingDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20.50 |
NCT02616731
|
HypospadiasDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB53 |
NCT02752308
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
NCT03778593
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT04895358
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
NCT02416739
|
Lateral epicondylitis of elbowDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB55.1 |
NCT05326763
|
Chronic lower extremities peripheral venous insufficiencyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD74 |
NCT01110512
|
Hodgkin lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B30 |
NCT00691210
|
OsteoporosisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83.1 |
NCT00330096
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
NCT02325583
|
Skin fungal infection disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA60 |
NCT01075984
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT04670081
|
FrecklesDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED61.0 |
NCT03392623
|
Obstruction of bile ductDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC10.02 |
NCT03418935
|
Hearing disorderDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB50-AB57 |
NCT00552786
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
NCT02596477
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
CYP1A1
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
CYP2C9
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
ACHE
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
CYP1A1
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
CA4
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
DPP4
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
ACHE
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
BLM
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
