CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Citrullus Colocynthis

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TCGATGCCTAAACATCAAACGACCCGCGAACGCGTTTACAAACAAACTGTCCGCGCTGGGGGGCGGGGGGAAGCATGCTCTCTGTGTGCCCCCTCCCCCTCAGTGCGCCTAAACCAAACCCCGGCGCAGGTCGCGCCAAGGAACTTGAAATGAATTTGCCTGCCCCCTGCCCCGGCCTCGGCGTGCGGGGGGCGGAGCATTCTTGTCGTATTACTCACAACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGGATCCCGCGAACCACCGAGTCTTTGAACGCAAGTTGCGCCCGGAGCCTTCTGGCCGAGGGCACGTCTGCCTGGGCGTCACGCATCGCTGCCCCCCCCACACAACACCCCACGCGGGCTCGTTGCATAGGCAGGGGCACACACTGGCCTCCCGTGCGCACCGTCGTGCGGATGGCTTAAATTCGAGTCCTCGGCGCACGTCGTCGCGACACTACGGTGGTTGATCCAACCTCGGTACCGCGTCGCGATCTTGACGCCGCCTCCTTGTGGACTCCTACACCGACCCTCCGAACGCCGGCCCCCAAAAGGAGACGCTCTCGA

Click for details-----ITS1

Click for details-----ITS2

ATCGCTGCCCCCCCCCCCCCCACACAACACCCCACGCGGGCTCGTTGCGTAGGTAGGGGCACACACTGGCCTCCCGTGCGCACCGTCGTGCGGATGGCTTAAATTCGAGTCCTCGGCGCACGTCGTCGCGACACTACGGTGGTTGATCCAACCTCGGTACCGCGTCGCGATCTTGACGCCGCCTCCTTGTGGACTCCTACACCGACCCTCCGAACGCCGTCCCCCAAAGGACGACGCTCTCG

Taxonomic Information

Plant ID: NPO1592
Plant Latin Name: Citrullus Colocynthis
Taxonomy Genus: Citrullus
Taxonomy Family: Cucurbitaceae

Plant External Links:

NCBI TaxonomyDB: 252529
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:

Israel; Australia; Algeria; India; Lebanon; Jordan; China; Nigeria; Iraq

Traditional Medicine System:

Sowa-Rigpa; Indian Folk; Unani; Siddha; Ayurveda; TCM; Homeopathy

Geographical Distribution

Israel; Australia; Algeria; Lebanon; India; China; Jordan; Nigeria; Iraq

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

31 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

15 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)