Collective Molecular Activities of the Plant: Vitex Negundo
Country/Region:
Pakistan; Guinea; Philippines; Indonesia; India; Malaysia; Vietnam; China; Sri Lanka; ThailandTraditional Medicine System:
Sowa-Rigpa; Indian Folk; Unani; Siddha; Ayurveda; TCMMedicinal Functions:
Antibacterial; Antitumor; Astringent; Expectorant; Febrifuge; Sedative; Tonic; Vermifuge
Afghanistan; Madagascar; Bangladesh; Guinea; Nepal; Cambodia; Somalia; Iran; Cuba; China; Thailand; Haiti; Tanzania; Maldives; Philippines; Indonesia; Mauritius; Trinidad and Tobago; Vietnam; Pakistan; Myanmar; South Africa; India; Malaysia; Mozambique; Sri Lanka; Japan; Taiwan; United States
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
388 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
289 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
207 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
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