Collective Molecular Activities of the Plant: Artemisia Vulgaris
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PLANiTS DNA barcode
Taxonomic Information
Plant ID: NPO1351
Plant Latin Name: Artemisia Vulgaris
Taxonomy Genus: Artemisia
Taxonomy Family: Asteraceae
Plant External Links:
NCBI TaxonomyDB:
4220
Plant-of-the-World-Online:
n.a.
Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Compounds Summary
Overview of Ingredients
23 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
18 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
9 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC99734
Ingredient ID: NPC94167
Ingredient ID: NPC92962
Ingredient ID: NPC70312
Ingredient ID: NPC489918
Ingredient ID: NPC48190
Ingredient ID: NPC317130
Ingredient ID: NPC309733
Ingredient ID: NPC292460
Ingredient ID: NPC285814
Ingredient ID: NPC278197
Ingredient ID: NPC270620
Ingredient ID: NPC252433
Ingredient ID: NPC227378
Ingredient ID: NPC212911
Ingredient ID: NPC204838
Ingredient ID: NPC201969
Ingredient ID: NPC196882
Ingredient ID: NPC187770
Ingredient ID: NPC17810
Ingredient ID: NPC167400
Ingredient ID: NPC157436
Ingredient ID: NPC135263
Classification of Human Proteins Collectively Targeted by the Plant
*The classification criteria of Drug Transporter (DTP), CYP450 are referred to DrugMap. Other molecular targets in CMAUP are classified as therapeutic targets.
.
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Drug Transporter | ATP-binding cassette | ABCG2 | ATP-binding cassette sub-family G member 2 | Q9UNQ0 | CHEMBL5393 |
| Cytochrome P450 | Cytochrome P450 family 2 | CYP2B6 | Cytochrome P450 2B6 | P20813 | CHEMBL4729 |
| Therapeutic Target | Enzyme | RECQL | ATP-dependent DNA helicase Q1 | P46063 | CHEMBL1293236 |
| Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
| Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR2 | Estrogen receptor beta | Q92731 | CHEMBL242 |
| Therapeutic Target | Oxidoreductase | AOX1 | Aldehyde oxidase | Q06278 | CHEMBL3257 |
| Drug Transporter | SLC superfamily of solute carriers | SLC6A4 | Serotonin transporter | P31645 | CHEMBL228 |
| Drug Transporter | SLC superfamily of solute carriers | SLCO1B1 | Solute carrier organic anion transporter family member 1B1 | Q9Y6L6 | CHEMBL1697668 |
| Drug Transporter | SLC superfamily of solute carriers | SLC6A3 | Dopamine transporter | Q01959 | CHEMBL238 |
| Drug Transporter | SLC superfamily of solute carriers | SLC6A2 | Norepinephrine transporter | P23975 | CHEMBL222 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | HCAR2 | Hydroxycarboxylic acid receptor 2 | Q8TDS4 | CHEMBL3785 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2B | Alpha-2b adrenergic receptor | P18089 | CHEMBL1942 |
| Therapeutic Target | Transferase | SULT1A1 | Sulfotransferase 1A1 | P50225 | CHEMBL1743291 |
Clinical Trials Summary
Overview
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 229 | |
 Plant level | 1 | |
Clinical trial details
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT00000555 | Women's Angiographic Vitamin and Estrogen Trial (WAVE) | menopause;Myocardial Ischemia | Ascorbate (NPC187770) | NP level |
| NCT00275418 | Beta Carotene From Natural Source for Patients With Non-Active Crohn's Disease | Crohn's disease | Beta Carotene (NPC17810) | NP level |
| NCT00271817 | To Evaluate Ezetimibe/Simvastatin and Niacin (Extended Release Tablet) in Patients With Type IIa or Type IIb Hyperlipidemia (0653A-091)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02344355 | A Phase 2 Trial of High-Dose Ascorbate in Glioblastoma Multiforme | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT04677049 | Study of Niacin in Glioblastoma | glioblastoma multiforme | Niacin (NPC167400) | NP level |
| NCT00953212 | Prophylaxis to Reduce Postoperative Atrial Fibrillation in Cardiac Surgery | atrial fibrillation;atrial flutter | Ascorbate (NPC187770) | NP level |
| NCT03410030 | Trial of Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT00170404 | TB Nutrition, Immunology and Epidemiology | tuberculosis | Niacin (NPC167400) | NP level |
| NCT03510715 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Homozygous Familial Hypercholesterolemia | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT04395768 | International ALLIANCE Study of Therapies to Prevent Progression of COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00184054 | Trial of Arsenic Trioxide With Ascorbic Acid in the Treatment of Adult Non-Acute Promyelocytic Leukemia (APL) Acute Myelogenous Leukemia | acute myeloid leukemia | Ascorbate (NPC187770) | NP level |
| NCT01550510 | Research Study of IV Vitamin C in Combination With Irinotecan vs Irinotecan Alone for Advanced Colorectal CA | colorectal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT03964688 | Effect of Vitamin C in Autologous Stem Cell Transplantations | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00000461 | Harvard Atherosclerosis Reversibility Project (HARP) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT03510884 | An Efficacy and Safety Study of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04630964 | The Effect of Psilocybin on MDD Symptom Severity and Synaptic Density | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT02606773 | "Novo C Plus" Vitamin C Containing Dietary Supplement Bioavailability in Healthy Subjects | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | Myocardial Ischemia | Ascorbate (NPC187770) | NP level |
| NCT00954525 | Intravenous Vitamin C in Combination With Standard Chemotherapy for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00661544 | Arsenic Trioxide With Ascorbic Acid and Melphalan for Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT04999137 | Evaluation of Safety and Dosing of a Vitamin C Bundle for Sepsis Treatment in Africa | Sepsis;septic shock | Ascorbate (NPC187770) | NP level |
| NCT00000161 | Randomized Trials of Vitamin Supplements and Eye Disease | cataract | Ascorbate (NPC187770);Beta Carotene (NPC17810) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | Myocardial Ischemia | Beta Carotene (NPC17810) | NP level |
| NCT00000541 | Women's Antioxidant and Folic Acid Cardiovascular Study (WAFACS) | myocardial infarction | Ascorbate (NPC187770);Beta Carotene (NPC17810) | NP level |
| NCT00152893 | To Determine if Chromium Nicotinate Supplementation Will Improve Insulin Resistance in HIV Patients With Metabolic Abnormalities | HIV infection | Niacin (NPC167400) | NP level |
| NCT01319734 | Vitamin C Supplementation Plus Hypoglycemic Agents Versus Hypoglycemic Agents Alone in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT04354428 | Treatment for COVID-19 in High-Risk Adult Outpatients | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT02521077 | Intravenous Ascorbic Acid in Women Receiving Adjuvant or Neo-Adjuvant Chemotherapy for Early Stage Breast Cancer | Fatigue | Ascorbate (NPC187770) | NP level |
| NCT01587963 | High Dose Vitamin C in the Critically Ill Patient | Shock | Ascorbate (NPC187770) | NP level |
| NCT01590303 | Outcome Following Vitamin C Administration in Sepsis | Sepsis | Ascorbate (NPC187770) | NP level |
| NCT03509350 | Vitamin C, Thiamine, and Steroids in Sepsis | Sepsis | Ascorbate (NPC187770) | NP level |
| NCT02168270 | Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma | anaplastic astrocytoma;anaplastic oligodendroglioma;gliosarcoma | Ascorbate (NPC187770) | NP level |
| NCT00536510 | Effect of MK0524A on Cholesterol Levels (0524A-048) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT03509662 | Vitamin C in Post-cardiac Arrest | cardiac arrest | Ascorbate (NPC187770) | NP level |
| NCT00062556 | Effect of Niacin ER/Lovastatin on Peak Walking Time & Claudication Onset Time in Patients With Intermittent Claudication | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT04482686 | Trial of Combination Therapy to Treat COVID-19 Infection | COVID-19;severe acute respiratory syndrome | Ascorbate (NPC187770) | NP level |
| NCT01005303 | Micronutrient Supplementation in Patients With Heart Failure | heart failure | Ascorbate (NPC187770);Niacin (NPC167400) | NP level |
| NCT00508989 | Niacin to Improve Blood Flow in People With Sickle Cell Disease | sickle cell anemia | Niacin (NPC167400) | NP level |
| NCT02780505 | Assessment of the Effect of Vitamin C on Anemia in Patients With Continuous Ambulatory Peritoneal Dialysis | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT03887169 | Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. | pulmonary alveolar proteinosis | Ascorbate (NPC187770) | NP level |
| NCT03680274 | Lessening Organ Dysfunction With VITamin C | COVID-19;Sepsis | Ascorbate (NPC187770) | NP level |
| NCT02018965 | Niacin on Immune Activation : a Proof-of-concept Study | HIV infection | Niacin (NPC167400) | NP level |
| NCT03334409 | Pazopanib Hydrochloride With or Without Ascorbic Acid in Treating Patients With Kidney Cancer That Is Metastatic or Cannot Be Removed by Surgery | clear cell renal carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01426438 | Endothelial Function, Lipoproteins, and Inflammation With Low HDL Cholesterol in HIV: ER Niacin Versus Fenofibrate | HIV-1 infection | Niacin (NPC167400) | NP level |
| NCT04046094 | Intravenous (IV) Vitamin C With Chemotherapy for Cisplatin Ineligible Bladder Cancer Patients | urinary bladder cancer | Ascorbate (NPC187770) | NP level |
| NCT04832009 | Reversing Glucose and Lipid-mediated Vascular Dysfunction | hypertension | Ascorbate (NPC187770) | NP level |
| NCT02107976 | Famine From Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes | diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT02602483 | Exploratory Study To Assess the Efficacy and Safety of a Triple Combination for Acute Pain Treatment in Patients With Temporomandibular Joint Disorders (TMJD). | temporomandibular joint disorder | Ascorbate (NPC187770) | NP level |
| NCT00376584 | Effect of an Investigational Compound on Tolerability of Extended Release Niacin (0524A-023)(COMPLETED) | Disorder of lipid metabolism;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00000599 | Cholesterol-Lowering Atherosclerosis Study (CLAS) | carotid artery disease;cerebral atherosclerosis;Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT03540758 | Regulation of Endogenous Glucose Production by Central KATP Channels | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT01368328 | Effect of the Chromium Nicotinate on Type 2 Diabetes | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT03148236 | Vitamin C in Atrial Fibrillation Ablation | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT02890992 | An 8-Week Dose-Finding Study to Evaluate the Efficacy and Safety of Alirocumab in Children and Adolescents With Heterozygous Familial Hypercholesterolemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT03541486 | A Clinical Trial Evaluating the Effect of Pharmacological Ascorbate on Radiation Therapy for Pancreatic Cancer Patients | pancreatic neoplasm | Ascorbate (NPC187770) | NP level |
| NCT00000553 | HDL-Atherosclerosis Treatment Study (HATS) | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00067899 | Oxidative Stress and Vitamin E Requirements | nicotine dependence | Ascorbate (NPC187770) | NP level |
| NCT01752491 | A Phase I Trial of High-Dose Ascorbate in Glioblastoma Multiforme | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT03624270 | Oral Arsenic Trioxide for Newly Diagnosed Acute Promyelocytic Leukaemia | acute promyelocytic leukemia | Ascorbate (NPC187770) | NP level |
| NCT03866174 | A Study of Psilocybin for Major Depressive Disorder (MDD) | major depressive disorder | Niacin (NPC167400) | NP level |
| NCT02969681 | Vitamin C Intravenously With Chemotherapy in Advanced Colorectal Cancer | colorectal neoplasm | Ascorbate (NPC187770) | NP level |
| NCT02791906 | Targeting Central Pulsatile Hemodynamics in Chronic Kidney Disease | chronic kidney disease | Ascorbate (NPC187770) | NP level |
| NCT03223519 | COMBOPROFEN for Treatment of Muscular Pain Associated With Delayed Onset Muscle Soreness (DOMS) | muscular disease | Ascorbate (NPC187770) | NP level |
| NCT02420314 | Pharmacological Ascorbate for Lung Cancer | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02225886 | Ascorbic Acid Administration in the Treatment of Anemia in Chronic Hemodialysed Patients | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT00082251 | Safety & Efficacy of a Combination Niacin ER/Simvastatin in Patients With Dyslipidemia: A Dose-Ranging Study - SEACOAST | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00269204 | Lipid Efficacy/Tolerability Study (0524A-020) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT04553666 | Reducing Frailty for Older Cancer Survivors Using Supplements | inflammation | Ascorbate (NPC187770) | NP level |
| NCT01221402 | Effect of Extended-Release Niacin on Saphenous Vein Graft Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT01587261 | Vitamin C for Severe Thermal Injuries | injury | Ascorbate (NPC187770) | NP level |
| NCT01080352 | Vitamin C as an Anti-cancer Drug | prostate adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT04801511 | Preoperative IMRT With Concurrent High-dose Vitamin C and mFOLFOX6 in Locally Advanced Rectal Cancer | rectum cancer | Ascorbate (NPC187770) | NP level |
| NCT00728910 | Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04703361 | Effects of Ketones and Niacin in Heart Failure Patients | systolic heart failure | Niacin (NPC167400) | NP level |
| NCT01104519 | A Study of Niaspan on Endothelium-Dependent and Endothelium-Independent Vascular Reactivity (0000-093) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT03828929 | Effect of IV Vitamin C, Thiamine, and Steroids on Mortality of Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT00493064 | To Study the Effectiveness and Safety of Niacin and a Topical Steroid Eye Drop to Treat Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT00289900 | Lipid Efficacy and Safety in Participants With Mixed Hyperlipidemia (MK-0524B-024) | Combined hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00300365 | Pioglitazone vs Placebo in Combination With Niacin Extended Release on Low HDL | metabolic syndrome | Niacin (NPC167400) | NP level |
| NCT04783792 | The Effect of Phenolic Compounds in Osteoarthritis; a Nutritional Intervention | osteoarthritis | Ascorbate (NPC187770) | NP level |
| NCT03872011 | Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT02424201 | Comparative Study on the Effects of Sublingual Misoprostol in Addition to Standard AMTSL in Low Risk Parturients in LASUTH, Ikeja. | postpartum hemorrhage | Ascorbate (NPC187770) | NP level |
| NCT05009355 | The Effect of Vitamin C on GCF Total Oxidant Capacity in Smoker Patients With Periodontitis | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT00536237 | MK0524A Phase IIb Study (0524A-011)(COMPLETED) | Flushing | Niacin (NPC167400) | NP level |
| NCT01295450 | Study to Evaluate the Efficacy and Tolerability of Apevinat BC Compared to Vitamin Complex | Anorexia | Ascorbate (NPC187770) | NP level |
| NCT04401150 | Lessening Organ Dysfunction With VITamin C - COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT04900792 | A Safety Study of Pharmacologic Ascorbate and Ferumoxytol in Addition to Standard of Care Chemoradiation in Glioblastoma | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT01050621 | Trial of Chemotherapy Plus Intravenous Vitamin C in Patients With Advanced Cancer for Whom Chemotherapy Alone is Only Marginally Effective | cancer | Ascorbate (NPC187770) | NP level |
| NCT03451266 | Effects of Vitamin C Administration on Extravascular Lung Water in Patients With Severe Features of Preeclampsia | preeclampsia | Ascorbate (NPC187770) | NP level |
| NCT05501548 | Phase II Study of PARP Inhibitor Olaparib and IV Ascorbate in Castration Resistant Prostate Cancer | prostate cancer | Ascorbate (NPC187770) | NP level |
| NCT02083575 | Role of Vitamin C to Augment Iron Chelation With DFP or DFX | beta-thalassemia major | Ascorbate (NPC187770) | NP level |
| NCT00920413 | Oral Vitamin C for Correction of Anemia in Patients Receiving Peritoneal Dialysis | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT00211562 | Adjunctive Supplementation of Antioxidants (Vitamins E + C) Plus Omega-3 Fatty Acids | schizophrenia | Ascorbate (NPC187770) | NP level |
| NCT00634998 | Vitamin C Supplementation as a Preventive Treatment of Diabetic Peripheral Neuropathy | diabetic neuropathy | Ascorbate (NPC187770) | NP level |
| NCT04530617 | Camostat and Artemisia Annua vs Placebo in COVID-19 Outpatients | Covid19|Diabetes|Hypertension|Obesity | Artemisia Vulgaris | Plant level As single plant |
| NCT02206425 | Ixazomib as a Replacement for Carfilzomib and Bortezomib for Multiple Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT04268849 | Trial of IV vs Oral Iron Treatment of Iron Deficiency Anemia in the Post-Operative Bariatric Surgical Patient | Iron deficiency anemia | Ascorbate (NPC187770) | NP level |
| NCT00325572 | Evaluation and Treatment of Copper/Zinc Imbalance in Children With Autism | autism | Ascorbate (NPC187770) | NP level |
| NCT03356483 | Efficacy of Psilocybin in OCD: a Double-Blind, Placebo-Controlled Study. | obsessive-compulsive disorder | Niacin (NPC167400) | NP level |
| NCT02297399 | Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients | diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT03437902 | Impact of Rutin and Vitamin C Combination on Oxidative Stress, Insulin Sensitivity and Lipid Profile in Type 2 Diabetic Patients | type 2 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT00258245 | Arsenic Trioxide and Ascorbic Acid Combined With Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00000512 | Familial Atherosclerosis Treatment Study | Myocardial Ischemia | Niacin (NPC167400) | NP level |
| NCT00006021 | Arsenic Trioxide Plus Vitamin C in Treating Patients With Recurrent or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT04446104 | A Preventive Treatment for Migrant Workers at High-risk of COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01720095 | Niapsan as Add -on Therapy to Antipsychotic Treatment in First Episode Psychosis | psychosis | Niacin (NPC167400) | NP level |
| NCT01321034 | Effect of Niacin in the Lipoprotein (a) Concentration | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00631111 | Study Evaluating the Efficacy of an Ibuprofen Effervescent Tablet in the Treatment of Post-Surgical Dental Pain | pain | Ascorbate (NPC187770) | NP level |
| NCT02833701 | Bevacizumab and Ascorbic Acid in Patients Treating With Recurrent High Grade Glioma | glioblastoma multiforme | Ascorbate (NPC187770) | NP level |
| NCT04335084 | A Study of Hydroxychloroquine, Vitamin C, Vitamin D, and Zinc for the Prevention of COVID-19 Infection | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01984073 | Effects of Niacin On Fatty Acid Trapping | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01083329 | Effect of Nicotinic Acid on Adipose Tissue Inflammation in Obese Subjects | obesity | Niacin (NPC167400) | NP level |
| NCT00269217 | Lipid Efficacy Study (0524B-022)(COMPLETED) | Combined hyperlipidemia;Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT03799094 | Vitamin C and Tyrosine Kinase Inhibitor in Lung Cancer Patients With Epidermal Growth Factor Receptor Mutations | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02730364 | An Efficacy and Safety Study of Theraflu Night Powder as Oral Solution for Cold and Flu | respiratory tract infectious disorder | Ascorbate (NPC187770) | NP level |
| NCT00150722 | High-Density Lipoprotein (HDL) Modulation and Endothelial Function | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT02390505 | Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery | complex regional pain syndrome | Ascorbate (NPC187770) | NP level |
| NCT00127218 | High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT00533312 | MK0524A Clinical Efficacy Study (0524A-026)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT02516670 | Docetaxel With or Without Ascorbic Acid in Treating Patients With Metastatic Prostate Cancer | metastatic prostate cancer | Ascorbate (NPC187770) | NP level |
| NCT01107730 | Vitamin C for Prophylaxis of Post-operative Atrial Fibrillation in On-pump Cardiac Surgery Procedures | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT00630877 | Evaluation of a Flushing ASsessment Tool (FAST) in Subjects Receiving Niacin Extended-release Plus Aspirin | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT02905591 | A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01364805 | New Treatment Option for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00120289 | Niacin Plus Statin to Prevent Vascular Events | stroke;atherosclerosis;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT01852890 | Gemcitabine, Ascorbate, Radiation Therapy for Pancreatic Cancer, Phase I | pancreatic neoplasm | Ascorbate (NPC187770) | NP level |
| NCT00626444 | Pilot Trial of Intravenous Vitamin C in Refractory Non-Hodgkin Lymphoma (NHL) | non-Hodgkins lymphoma | Ascorbate (NPC187770) | NP level |
| NCT00943124 | MK0524B Bioequivalence Study (0524B-070) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01054508 | Effect of Tredaptive on Serum Lipoproteins and Inflammatory Markers | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT01014546 | Arsenic Trioxide With or Without Ascorbic Acid in Treating Patients With Myelofibrosis | essential thrombocythemia;polycythemia vera;primary myelofibrosis | Ascorbate (NPC187770) | NP level |
| NCT04261036 | Vitamin C for the Prevention of UTI in Women Who Undergo Elective Gynecological Surgeries | urinary tract infection | Ascorbate (NPC187770) | NP level |
| NCT03800667 | Vitamin C for the Prevention of UTI in Women Who Undergo Elective GYN Surgeries | urinary tract infection | Ascorbate (NPC187770) | NP level |
| NCT02109315 | Vitamin C and Liraglutide Effects on Hypoglycemia-induced Oxidative Stress, Inflammation and Endothelial Dysfunction in Type 1 Diabetes. | type 1 diabetes mellitus | Ascorbate (NPC187770) | NP level |
| NCT00329498 | L-Ascorbic Acid Depletion to Treat Acute Myeloid Leukemia and Myelodysplastic Syndromes | acute myeloid leukemia;myelodysplastic syndrome | Ascorbate (NPC187770) | NP level |
| NCT00441207 | Study of High-Dose Intravenous (IV) Vitamin C Treatment in Patients With Solid Tumors | cancer | Ascorbate (NPC187770) | NP level |
| NCT04363216 | Pharmacologic Ascorbic Acid as an Activator of Lymphocyte Signaling for COVID-19 Treatment | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01502280 | Fluorescence-guided Surgery for Low- and High-grade Gliomas | glioma | Ascorbate (NPC187770) | NP level |
| NCT00271635 | Ascorbic Acid Treatment in CMT1A Trial (AATIC) | Charcot-Marie-Tooth disease | Ascorbate (NPC187770) | NP level |
| NCT05452772 | 5-HT2A Agonist Psilocybin in the Treatment of Tobacco Use Disorder | nicotine dependence | Niacin (NPC167400) | NP level |
| NCT00633581 | Efficacy of Vitamin C Injection on Fatigue in Workers After Work | Fatigue | Ascorbate (NPC187770) | NP level |
| NCT03592693 | Vitamin C, Hydrocortisone and Thiamine for Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT03797443 | High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00317811 | Bortezomib, Ascorbic Acid, and Melphalan in Treating Patients With Newly Diagnosed Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT02369822 | Trial of Vitamin C as Add on Therapy for Children With Idiopathic Epilepsy | epilepsy | Ascorbate (NPC187770) | NP level |
| NCT00626392 | Study to Evaluate the EFFECTS of Acetylsalicylic Acid (ASA) on Niaspan®-Induced Flushing in Subjects With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT01905150 | Ph 2 Trial of Vitamin C & G-FLIP (Low Doses Gemcitabine, 5FU, Leucovorin, Irinotecan, Oxaliplatin) for Pancreatic Cancer | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01583647 | A Study of Extended-release (ER) Niacin/Laropiprant in Adolescents With Heterozygous Familial Hypercholesterolemia (MK-0524A-158) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00734695 | Comparing the Use of Vitamin c (Ascorbic Acid) in Eye Burn in Subconjunctival Injection to Topical or Oral Treatment. | burn | Ascorbate (NPC187770) | NP level |
| NCT05029037 | High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00944645 | MK0524A Bioequivalence Study (0524A-059) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04344184 | SAFEty Study of Early Infusion of Vitamin C for Treatment of Novel Coronavirus Acute Lung Injury (SAFE EVICT CORONA-ALI) | acute lung injury;COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01715597 | Study on the Effect of Intravenous Ascorbic Acid on Intraoperative Blood Loss in Women With Uterine Myoma | uterine fibroid | Ascorbate (NPC187770) | NP level |
| NCT03602235 | High Dose Ascorbic Acid for Plasma Cell Disorders | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00384293 | Carotid IMT (Intima Media Thickening) Study (0524A-041)(TERMINATED) | familial hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT03752918 | The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD. | post-traumatic stress disorder | Niacin (NPC167400) | NP level |
| NCT03333278 | The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial | Sepsis;septic shock | Ascorbate (NPC187770) | NP level |
| NCT00533611 | Effect of MK0524A on Flushing Caused by Niacin (0524A-056) | Flushing | Niacin (NPC167400) | NP level |
| NCT00000161 | Randomized Trials of Vitamin Supplements and Eye Disease | macular degeneration | Beta Carotene (NPC17810);Ascorbate (NPC187770) | NP level |
| NCT04357782 | Administration of Intravenous Vitamin C in Novel Coronavirus Infection (COVID-19) and Decreased Oxygenation | hypoxia;COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT02735707 | Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia | COVID-19;influenza;pneumonia | Ascorbate (NPC187770) | NP level |
| NCT02678234 | An Efficacy and Safety Study of Theraflu Day Powder as Oral Solution for Cold and Flu | respiratory tract infectious disorder | Ascorbate (NPC187770) | NP level |
| NCT02734147 | High Dose Intravenous Ascorbic Acid in Severe Sepsis | Sepsis | Ascorbate (NPC187770) | NP level |
| NCT00111891 | An Investigational Drug Study Evaluating a Novel Approach to Treat Dyslipidemia (0524A-032) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00378833 | Tolerability of MK0524A Versus Niacin Extended-Release (0524A-054) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT04921189 | Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors | cardiac arrest | Ascorbate (NPC187770) | NP level |
| NCT02655913 | Safety and Efficacy of Vitamin C Infusion in Combination With Local mEHT to Treat Non Small Cell Lung Cancer | non-small cell lung carcinoma | Ascorbate (NPC187770) | NP level |
| NCT03418038 | Ascorbic Acid and Combination Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma or Clonal Cytopenia of Undetermined Significance | Hodgkins lymphoma | Ascorbate (NPC187770) | NP level |
| NCT04035096 | The Effectiveness of High-dose Intravenous Vitamin c With Very Low Carbohydrate Diet for Terminal Colon Cancer Patients | malignant colon neoplasm | Ascorbate (NPC187770) | NP level |
| NCT00227682 | Arsenic Trioxide, Thalidomide, Dexamethasone, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00903617 | Study to Test GSK256073 in Patients With Dyslipidemia | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00664287 | Extended Release (ER) Niacin/Laropiprant Add on Study (0524A-082) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00080275 | Evaluation of the Safety & Efficacy of a Combination of Niacin ER & Simvastatin in Patients With Dyslipidemia (OCEANS) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT03697239 | High Dose Ascorbic Acid (AA) + Nanoparticle Paclitaxel Protein Bound + Cisplatin + Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT02702492 | PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA) | non-Hodgkins lymphoma | Niacin (NPC167400) | NP level |
| NCT03649633 | Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock | septic shock | Ascorbate (NPC187770) | NP level |
| NCT04928495 | Clinical Trial With N-acetylcysteine and Bromhexine for COVID-19 | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT01891747 | A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma | malignant glioma | Ascorbate (NPC187770) | NP level |
| NCT00957359 | Psilocybin Cancer Anxiety Study | cancer | Niacin (NPC167400) | NP level |
| NCT00085345 | Melphalan, Arsenic Trioxide, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT00000482 | Coronary Drug Project | Myocardial Ischemia;myocardial infarction | Niacin (NPC167400) | NP level |
| NCT00485758 | Extended Niacin/Laropiprant in Patients With Type 2 Diabetes (0524A-069) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT00803530 | Study of Association of Arsenic Trioxide (ATO) and Ascorbic Acid in Myelodysplastic Syndromes | myelodysplastic syndrome | Ascorbate (NPC187770) | NP level |
| NCT00469209 | Velcade, Trisenox, Vitamin C and Melphalan for Myeloma Patients | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT01426490 | The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer | colorectal carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00796887 | Randomized, Controlled Trial of Extended-Release Niacin (Niaspan®) to Augment Subacute Ischemic Stroke Recovery | Ischemic stroke | Niacin (NPC167400) | NP level |
| NCT01555489 | Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca | pancreatic carcinoma | Ascorbate (NPC187770) | NP level |
| NCT02109614 | Early Aortic Valve Lipoprotein(a) Lowering Trial | aortic stenosis | Niacin (NPC167400) | NP level |
| NCT04404387 | Lessening Organ Dysfunction With VITamin C in Septic ARDS | acute respiratory distress syndrome | Ascorbate (NPC187770) | NP level |
| NCT04898023 | Zinc and Green Tea Extract for Community Respiratory Viral Infections | viral disease | Ascorbate (NPC187770) | NP level |
| NCT02868151 | Effect of Oral Vitamin C in Assessing the Severity of Oral Mucositis in Chemoradiation of Head and Neck Cancers | oral mucositis | Ascorbate (NPC187770) | NP level |
| NCT01071291 | Effects of Niaspan™ on High-density Lipoprotein (HDL) in Healthy Male Subjects (0000-069) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT04516681 | IV Ascorbic Acid in Peritoneal Metastatic Colorectal Cancer | colorectal carcinoma | Ascorbate (NPC187770) | NP level |
| NCT01057615 | Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma | asthma | Ascorbate (NPC187770) | NP level |
| NCT00961636 | A Long-term Study of ERN/LRPT (Extended Release Niacin/Laropiprant [MK0524A]) in Patients With Dyslipidemia (0524A-102) | Disorder of lipid metabolism | Niacin (NPC167400) | NP level |
| NCT00203476 | A Prospective, Open Label Comparison of Ezetimibe, Niacin, and Colestipol as Adjunct Therapy in Lipid Reduction | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT03508726 | High Dose Ascorbate With Preoperative Radiation in Patients With Locally Advanced Soft Tissue Sarcomas | soft tissue sarcoma | Ascorbate (NPC187770) | NP level |
| NCT00855257 | Assessment of Endothelial Vasomotricity After Treatment by Nicotinic Acid in Acute Coronary Syndrome | acute coronary syndrome | Niacin (NPC167400) | NP level |
| NCT00769132 | A Study to Evaluate the Effects of Extended Release (ER) Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites in Subjects With High Cholesterol (0524A-075)(COMPLETED) | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00652431 | Assessment of Interaction Between Vytorin and Niaspan in Healthy Subjects (P04955AM2) | Hypercholesterolemia;hyperlipidemia | Niacin (NPC167400) | NP level |
| NCT00284427 | Safety of Antioxidants During GYN Cancer Care | cervical cancer;ovarian cancer | Ascorbate (NPC187770) | NP level |
| NCT00397657 | Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on Atherosclerosis | atherosclerosis | Niacin (NPC167400) | NP level |
| NCT03522922 | Efficacy of Microneedling With Topical Vitamin C in Treatment of Acne Scarring | acne | Ascorbate (NPC187770) | NP level |
| NCT04279535 | Topical Vitamin C for Treatment of Basal Cell Cancer | basal cell carcinoma | Ascorbate (NPC187770) | NP level |
| NCT00804843 | Merck Carotid Atherosclerosis Trial (MK-0000-111)(COMPLETED) | carotid atherosclerosis | Niacin (NPC167400) | NP level |
| NCT01580683 | Vitamin C and Atrial Fibrillation After Cardiac Surgery | atrial fibrillation | Ascorbate (NPC187770) | NP level |
| NCT02793648 | Effectiveness of Ascorbic Acid and Tocopherol for Depression in Elderly. | depressive disorder | Ascorbate (NPC187770) | NP level |
| NCT03685773 | The Role of Hepatic Denervation in the Dysregulation of Glucose Metabolism in Liver Transplant Recipients | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT04347889 | Preventing COVID-19 in Healthcare Workers With HCQ: A RCT | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00500045 | Retrospective Study of the Effectiveness and Safety of Niacin and Steroid Eye Drops for Retinal Vein Occlusions | retinal vein occlusion | Niacin (NPC167400) | NP level |
| NCT05283954 | Use of a Combined Regimen of Fluoxetine, Prednisolone and Ivermectin in the Treatment of Mild COVID-19 to Prevent Disease Progression Progression in Papua New Guinea | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT04334512 | A Study of Quintuple Therapy to Treat COVID-19 Infection | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00618995 | A Study to Evaluate the Effects of ER Niacin/Laropiprant, Laropiprant, ER Niacin, and Placebo on Urinary Prostanoid Metabolites (0524A-079)(COMPLETED) | type 2 diabetes mellitus | Niacin (NPC167400) | NP level |
| NCT04715022 | Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study) | hypertension | Ascorbate (NPC187770) | NP level |
| NCT03224572 | The Effect of Vitamin C on Quality of Life of Terminal Cancer Patients | ascorbic acid deficiency | Ascorbate (NPC187770) | NP level |
| NCT00112879 | Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Treating Patients With Multiple Myeloma | multiple myeloma | Ascorbate (NPC187770) | NP level |
| NCT02186158 | Interest of Ascorbic Acid in the Management of Pneumonia in Elderly People Hospitalized. | pneumonia | Ascorbate (NPC187770) | NP level |
| NCT04370288 | Clinical Application of Methylene Blue for Treatment of Covid-19 Patients | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT00071266 | The Dose Response of Niacin ER/Lovastatin on Peak Walking Time (PWT) in Patients With Intermittent Claudication - TROPIC | intermittent vascular claudication | Niacin (NPC167400) | NP level |
| NCT00388856 | Antioxidant Supplementation in Pregnant Women With Low Antioxidant Status | preeclampsia | Ascorbate (NPC187770) | NP level |
| NCT03908333 | High Dose Ascorbic Acid and Nanoparticle Paclitaxel Protein Bound and Cisplatin and Gemcitabine (AA NABPLAGEM) in Patients Who Have Metastatic Pancreatic Cancer | pancreatic ductal adenocarcinoma | Ascorbate (NPC187770) | NP level |
| NCT00484510 | High Dose Ascorbic Acid Treatment of CMT1A | Charcot-Marie-Tooth disease type 1A | Ascorbate (NPC187770) | NP level |
| NCT02631668 | the Efficacy and Safety of Vitamin C for Iron Supplementation in Adult IDA Patients | anemia (phenotype) | Ascorbate (NPC187770) | NP level |
| NCT01071525 | The Effect of Niacin Administration on Oxidative Stress in Patients With Hypercholesterolmia, as Measured by the Use of a Novel Biomarker | Hypercholesterolemia | Niacin (NPC167400) | NP level |
| NCT00000152 | Randomized Trial of Beta-Carotene and Macular Degeneration | macular degeneration | Beta Carotene (NPC17810) | NP level |
| NCT03188445 | Intravenous Iron Isomaltoside Versus Oral Iron Supplementation for Treatment of Iron Deficiency in Pregnancy. | Iron deficiency anemia | Ascorbate (NPC187770) | NP level |
| NCT03015675 | IV Ascorbic Acid in Advanced Gastric Cancer | gastric cancer | Ascorbate (NPC187770) | NP level |
| NCT04328961 | Hydroxychloroquine for COVID-19 Post-exposure Prophylaxis (PEP) | COVID-19 | Ascorbate (NPC187770) | NP level |
| NCT03066115 | Impact of NOS, COX, and ROS Inhibition on Cerebral Blood Flow Regulation | hypoxia | Ascorbate (NPC187770) | NP level |
| NCT00000600 | Vitamin E and C to Slow Progression of Common Carotid Artery Plaque Build-Up | carotid artery disease;cerebral atherosclerosis;heart disease | Ascorbate (NPC187770) | NP level |
| NCT03175341 | Intravenous Ascorbic Acid Supplementation in Neoadjuvant Chemotherapy for Breast Cancer | breast cancer | Ascorbate (NPC187770) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NR3C1
NCT03685773,NCT01319734,NCT03437902,NCT01368328,NCT00618995,NCT00485758,NCT03540758 |
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
ESR2
NCT01590303,NCT04999137,NCT03680274,NCT03333278,NCT02734147,NCT03509350 |
Ischaemic heart diseases, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA6Z |
NCT00000541,NCT00000482,NCT00000555,NCT00000553,NCT00000461,NCT00000512,NCT00000599
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
NCT00378833,NCT00203476,NCT01583647,NCT00652431,NCT00376584,NCT00384293,NCT00536510
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT03649633,NCT03333278,NCT03592693,NCT03828929,NCT03872011,NCT04999137
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B81 |
SLC6A4,SLC6A2,SLC6A3
NCT04530617 NCT01083329 |
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ADRA2B,SLC6A2,NR3C1,SLC6A3,SLC6A4
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
AOX1,ESR1,ESR2,NR3C1
NCT05501548 |
Coronary atherosclerosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA80 |
NCT00150722,NCT01221402,NCT00127218,NCT00120289,NCT00397657
|
Malignant neoplasm of pancreas, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.Z |
NCT01905150,NCT03797443,NCT01555489,NCT01364805,NCT00954525
|
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT01752491,NCT04677049,NCT04900792,NCT02344355,NCT02833701
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
AOX1,SULT1A1,HCAR2,RECQL,SLC6A3
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
ESR1
NCT04530617 NCT02297399,NCT02107976 |
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
SLC6A4,SLC6A3,NR3C1,SLC6A2
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
ESR1,ESR2,NR3C1
NCT03175341 |
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
SLC6A2,SLC6A4
NCT00067899,NCT05452772 |
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
SLC6A2,SLC6A3,ADRA2B,SLC6A4
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
NR3C1,SLC6A2,SLC6A4,SLC6A3
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
SLC6A4,ADRA2B,SLC6A2
NCT00631111 |
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT01580683,NCT00953212,NCT01107730,NCT03148236
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
NCT02655913,NCT02420314,NCT03799094,NCT02905591
|
AnemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00-3A9Z |
NCT02780505,NCT00920413,NCT02225886,NCT02631668
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
ABCG2,HCAR2,RECQL,CYP2B6
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
AOX1,ADRA2B,SULT1A1,ESR1
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT04530617
NCT04832009,NCT04715022 |
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
SLC6A2,SLC6A3,SLC6A4
|
Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
SLC6A2,SLC6A3,SLC6A4
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
NR3C1,ESR1,AOX1
|
Binge eating disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B82 |
SLC6A3,SLC6A2,SLC6A4
|
FatigueDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG22 |
SLC6A2
NCT00633581,NCT02521077 |
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR2,ESR1,SLC6A4
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
SLC6A2,SLC6A4,SLC6A3
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ESR2,HCAR2,ESR1
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
SLC6A2
NCT04703361,NCT01005303 |
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT00120289,NCT00000541,NCT00000482
|
Vitamin C deficiency, unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B56.Z |
NCT03224572,NCT05009355,NCT02606773
|
Mixed hyperlipidaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.2 |
NCT00269217,NCT00269204,NCT00289900
|
AdenocarcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D40 |
NCT03908333,NCT03697239,NCT03410030
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT00062556,NCT00071266,NCT04553666
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT00441207,NCT01050621,NCT00957359
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
NCT01426490,NCT02969681,NCT04516681
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
SLCO1B1,SLC6A3
NCT01080352 |
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HCAR2,CYP2B6,SLC6A4
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
ESR2,SLC6A3,SLC6A4
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
AOX1,ESR2,RECQL
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
ADRA2B,SLCO1B1,SLC6A2
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
CYP2B6,SLCO1B1,SLC6A2
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
SLCO1B1,CYP2B6,SLC6A2
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ESR2,ADRA2B,SLC6A2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
SLCO1B1,CYP2B6,SLC6A3
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HCAR2,SLC6A3,SLC6A2
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
CYP2B6,ESR1,SLC6A4
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
HCAR2,SLC6A2,SLC6A4
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ABCG2,SLCO1B1,CYP2B6
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
NR3C1,SLC6A3,SLC6A2
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
SLC6A2,SLC6A4
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NR3C1,ESR1
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
SLC6A4
NCT00211562 |
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
SLC6A2,ESR1
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1
NCT04898023 |
Soft tissue disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB56 |
SLC6A4
NCT03508726 |
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
NR3C1,ESR2
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
SLC6A2,SLC6A4
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
NR3C1
NCT01057615 |
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
NR3C1,ESR2
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
HCAR2
NCT00796887 |
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
SLC6A2,SLC6A4
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
ESR2,NR3C1
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
SLC6A4,ESR2
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NR3C1,ABCG2
|
Stomach diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA43-DA4Y |
SLC6A3,SLC6A2
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NR3C1,NR3C1
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SLC6A3,SLC6A4
|
Vitamin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55-5B5F |
AOX1,NR3C1
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1
NCT03522922 |
Asymptomatic stenosis of intracranial or extracranial arteryDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD55 |
NCT00000600,NCT00000599
|
FlushingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME64.4 |
NCT00533611,NCT00536237
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT02186158,NCT02735707
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
NCT00329498,NCT00803530
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT02018965,NCT00152893
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
NCT03451266,NCT00388856
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT00000161,NCT00000152
|
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
NCT03541486,NCT01852890
|
Iron deficiency anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00 |
NCT04268849,NCT03188445
|
Upper respiratory tract disorderDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0Z |
NCT02678234,NCT02730364
|
Cerebrovascular diseases, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B2Z |
NCT00000599,NCT00000600
|
Single episode depressive disorder, severe, without psychotic symptomsDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70.3 |
NCT04630964,NCT03866174
|
Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
NCT04261036,NCT03800667
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
HCAR2
NCT00275418 |
Glioma, malignantDisease Category: X.Extension CodesDisease ICD-11 Code: XH4RQ3 |
NCT01891747,NCT01502280
|
Malignant lymphoma, not elsewhere classifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33.5 |
NCT02702492,NCT00626444
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
NCT00329498,NCT00184054
|
Retinal vascular occlusionDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B74 |
NCT00500045,NCT00493064
|
AsphyxiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11.1 |
NCT04357782,NCT03066115
|
Cardiac arrestDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC82 |
NCT03509662,NCT04921189
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
HCAR2,ESR1
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
SLC6A2,NR3C1
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
SLC6A2,SLC6A4
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
SLCO1B1,SLC6A3
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
SLCO1B1,SLC6A2
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
SLCO1B1,HCAR2
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
SULT1A1,ABCG2
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
SLC6A3,SLC6A2
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
HCAR2,CYP2B6
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
ADRA2B,SLC6A2
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
SLC6A4,ABCG2
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
AOX1,HCAR2
|
COVID-19Disease Category: 25.Codes for special purposesDisease ICD-11 Code: RA01 |
NCT04530617
NCT04344184,NCT04401150,NCT04363216,NCT04328961,NCT04395768,NCT04482686,NCT04334512,NCT04335084,NCT04347889,NCT04354428,NCT05283954,NCT04928495,NCT04446104,NCT02735707,NCT03680274,NCT05029037,NCT04357782,NCT04370288 |
Inborn lipid metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C52 |
HCAR2
NCT02890992,NCT01104519,NCT00903617,NCT00630877,NCT03510884,NCT01071291,NCT00728910,NCT01984073,NCT00961636,NCT00944645,NCT00664287,NCT00626392,NCT00111891,NCT00376584,NCT00943124 |
HypercholesterolaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80.0 |
NCT00652431,NCT00536510,NCT01054508,NCT01321034,NCT00533312,NCT00203476,NCT00269217,NCT00082251,NCT00769132,NCT00378833,NCT03510715,NCT01071525,NCT00080275,NCT00271817
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
NCT00085345,NCT00317811,NCT00469209,NCT03602235,NCT00227682,NCT03964688,NCT00112879,NCT00258245,NCT00661544,NCT02206425,NCT00006021
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
SLC6A4
|
Acute painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG31 |
SLC6A2
|
Intracranial injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07 |
SLC6A3
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
SLC6A4
|
Adrenomedullary hyperfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A75 |
SLC6A2
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
ABCG2
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
NR3C1
|
Adaptive immunity immunodeficiencyDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01 |
NR3C1
|
Otitis externaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA00-AA13 |
NR3C1
|
Ejaculatory dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA03 |
SLC6A4
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
ESR2
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
SLC6A3
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
SLC6A2
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
NarcolepsyDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A20 |
SLC6A3
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
SLC6A3
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
NR3C1
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
SLC6A2
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
SLC6A4
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
ESR2
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
SLC6A4
|
Spine/trunk injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51 |
NR3C1
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
HCAR2
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
NR3C1
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
SLC6A4
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
HCAR2
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
ESR1
|
Adrenogenital disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A71 |
NR3C1
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NR3C1
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NR3C1
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
ESR1
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
NR3C1
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
SLC6A2
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NR3C1
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NR3C1
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1
|
DyslipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80-5C81 |
HCAR2
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
ESR1
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
ESR1
|
concerning food/fluid intake symptomDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG43 |
SLC6A4
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
MenopauseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30.0 |
NCT00000555
|
Other specified malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NCT01550510
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT04783792
|
Injury of lung, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NB32.3Z |
NCT04344184
|
Complex regional pain syndromeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30.04 |
NCT02390505
|
Disorders of muscles, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB3Z |
NCT03223519
|
GliosarcomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH9RC8 |
NCT02168270
|
Malignant neoplasm metastasis in male genital organsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E06 |
NCT02516670
|
Severe acute respiratory syndromeDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D65 |
NCT04482686
|
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
NCT00000600
|
Temporomandibular joint disordersDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0E.8 |
NCT02602483
|
Oligodendroglioma, anaplasticDisease Category: X.Extension CodesDisease ICD-11 Code: XH8844 |
NCT02168270
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT02109315
|
Aortic valve stenosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB70 |
NCT02109614
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
NCT00284427
|
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT00508989
|
Atherosclerotic chronic arterial occlusive disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD40.Z |
NCT00804843
|
Clear cell renal cell carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH46F1 |
NCT03334409
|
Hereditary sensory or autonomic neuropathy, unspecifiedDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C21.Z |
NCT00271635
|
Burn and burn infectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND90-NE2Z |
NCT00734695
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
NCT00120289
|
MyelofibrosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A22 |
NCT01014546
|
Basal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C32 |
NCT04279535
|
Acute respiratory distress syndromeDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB00 |
NCT04404387
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
NCT00300365
|
Duplications of the short arm of chromosome 17Disease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD41.G1 |
NCT00484510
|
Human immunodeficiency virus type 1Disease Category: X.Extension CodesDisease ICD-11 Code: XN8LD |
NCT01426438
|
Uterine fibroidDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E66 |
NCT01715597
|
Schizophrenia or other primary psychotic disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A2Z |
NCT01720095
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
NCT02369822
|
ShockDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG40 |
NCT01587963
|
Acute promyelocytic leukaemiaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1A50 |
NCT03624270
|
Macro reentrant atrial tachycardia, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.2Z |
NCT00953212
|
Obsessive-compulsive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B20 |
NCT03356483
|
Pulmonary alveolar proteinosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB04.31 |
NCT03887169
|
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT04046094
|
Acute ischaemic heart disease, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA4Z |
NCT00855257
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
NCT00170404
|
Oral mucositisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA01 |
NCT02868151
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
NCT00000161
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
NCT02735707
|
Rectum cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B92 |
NCT04801511
|
Beta thalassaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A50.2 |
NCT02083575
|
Diabetic polyneuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C03.0 |
NCT00634998
|
Polycythaemia veraDisease Category: X.Extension CodesDisease ICD-11 Code: XH0453 |
NCT01014546
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT02791906
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
NCT03015675
|
Astrocytoma, anaplasticDisease Category: X.Extension CodesDisease ICD-11 Code: XH96C7 |
NCT02168270
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
NCT00325572
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT02793648
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
NCT00284427
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
NCT01587261
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
NCT01014546
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
NCT03752918
|
Hodgkin lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B30 |
NCT03418038
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
NCT02424201
|
AnorexiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG43.7 |
NCT01295450
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT04035096
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
HCAR2
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
ADRA2B
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
HCAR2
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
ABCG2
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
HCAR2
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
ABCG2
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
SLC6A3
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
ADRA2B
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
HCAR2
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2
|
Malaria, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F4Z |
HCAR2
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
HCAR2
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
HCAR2
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
Plant-Targeted Human Disease Network
>> Targets derived from weak experimental activities
