Plant ID: NPO13106
Plant Latin Name: Rhodomyrtus Tomentosa
Taxonomy Genus: Rhodomyrtus
Taxonomy Family: Myrtaceae
NCBI TaxonomyDB:
98583
Plant-of-the-World-Online:
n.a.
India; Indonesia; China; Malaysia
Ingredient ID: NPC95615
Ingredient ID: NPC92943
Ingredient ID: NPC92869
Ingredient ID: NPC90486
Ingredient ID: NPC85210
Ingredient ID: NPC836
Ingredient ID: NPC81511
Ingredient ID: NPC76376
Ingredient ID: NPC74539
Ingredient ID: NPC73980
Ingredient ID: NPC72652
Ingredient ID: NPC72042
Ingredient ID: NPC71339
Ingredient ID: NPC70691
Ingredient ID: NPC65134
Ingredient ID: NPC62469
Ingredient ID: NPC58427
Ingredient ID: NPC53559
Ingredient ID: NPC5280
Ingredient ID: NPC502
Ingredient ID: NPC49074
Ingredient ID: NPC485219
Ingredient ID: NPC485218
Ingredient ID: NPC485217
Ingredient ID: NPC485216
Ingredient ID: NPC485215
Ingredient ID: NPC485214
Ingredient ID: NPC485213
Ingredient ID: NPC485212
Ingredient ID: NPC485211
Ingredient ID: NPC46254
Ingredient ID: NPC43246
Ingredient ID: NPC42793
Ingredient ID: NPC38742
Ingredient ID: NPC38212
Ingredient ID: NPC33415
Ingredient ID: NPC32991
Ingredient ID: NPC322171
Ingredient ID: NPC314217
Ingredient ID: NPC31279
Ingredient ID: NPC312132
Ingredient ID: NPC311783
Ingredient ID: NPC311255
Ingredient ID: NPC302857
Ingredient ID: NPC296071
Ingredient ID: NPC290598
Ingredient ID: NPC28828
Ingredient ID: NPC285197
Ingredient ID: NPC283170
Ingredient ID: NPC278620
Ingredient ID: NPC277400
Ingredient ID: NPC269242
Ingredient ID: NPC265800
Ingredient ID: NPC26536
Ingredient ID: NPC264784
Ingredient ID: NPC263089
Ingredient ID: NPC261644
Ingredient ID: NPC258476
Ingredient ID: NPC257124
Ingredient ID: NPC252587
Ingredient ID: NPC251666
Ingredient ID: NPC247553
Ingredient ID: NPC247139
Ingredient ID: NPC247123
Ingredient ID: NPC246654
Ingredient ID: NPC245020
Ingredient ID: NPC244315
Ingredient ID: NPC239039
Ingredient ID: NPC235260
Ingredient ID: NPC235190
Ingredient ID: NPC232375
Ingredient ID: NPC232141
Ingredient ID: NPC226669
Ingredient ID: NPC225709
Ingredient ID: NPC217781
Ingredient ID: NPC216825
Ingredient ID: NPC214971
Ingredient ID: NPC210456
Ingredient ID: NPC204701
Ingredient ID: NPC204388
Ingredient ID: NPC202992
Ingredient ID: NPC200838
Ingredient ID: NPC200684
Ingredient ID: NPC196776
Ingredient ID: NPC195355
Ingredient ID: NPC192744
Ingredient ID: NPC191103
Ingredient ID: NPC19003
Ingredient ID: NPC187021
Ingredient ID: NPC182468
Ingredient ID: NPC179987
Ingredient ID: NPC176819
Ingredient ID: NPC175771
Ingredient ID: NPC172625
Ingredient ID: NPC169755
Ingredient ID: NPC168290
Ingredient ID: NPC163984
Ingredient ID: NPC162169
Ingredient ID: NPC157340
Ingredient ID: NPC153861
Ingredient ID: NPC152384
Ingredient ID: NPC149203
Ingredient ID: NPC145463
Ingredient ID: NPC13990
Ingredient ID: NPC137949
Ingredient ID: NPC13449
Ingredient ID: NPC133953
Ingredient ID: NPC13304
Ingredient ID: NPC13143
Ingredient ID: NPC129206
Ingredient ID: NPC125085
Ingredient ID: NPC12455
Ingredient ID: NPC117299
Ingredient ID: NPC115919
Ingredient ID: NPC112866
Ingredient ID: NPC111888
Ingredient ID: NPC111690
Ingredient ID: NPC110699
Ingredient ID: NPC106486
Ingredient ID: NPC104190
Ingredient ID: NPC100773
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
Therapeutic Target | Hydrolase | CDA | Cytidine deaminase | P32320 | CHEMBL4502 |
Therapeutic Target | Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
Therapeutic Target | Nuclear hormone receptor subfamily 1 | NR1H4 | Bile acid receptor FXR | Q96RI1 | CHEMBL2047 |
Therapeutic Target | Other cytosolic protein | MAPT | Microtubule-associated protein tau | P10636 | CHEMBL1293224 |
Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
Drug Transporter | Potassium channels | KCNH2 | HERG | Q12809 | CHEMBL240 |
Therapeutic Target | Serine protease | F10 | Coagulation factor X | P00742 | CHEMBL244 |
Drug Transporter | SLC superfamily of solute carriers | SLC6A4 | Serotonin transporter | P31645 | CHEMBL228 |
Therapeutic Target | Small molecule receptor (family A GPCR) | DRD3 | Dopamine D3 receptor | P35462 | CHEMBL234 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HTR2B | Serotonin 2b (5-HT2b) receptor | P41595 | CHEMBL1833 |
Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2A | Alpha-2a adrenergic receptor | P08913 | CHEMBL1867 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HTR2C | Serotonin 2c (5-HT2c) receptor | P28335 | CHEMBL225 |
Therapeutic Target | Small molecule receptor (family A GPCR) | HTR2A | Serotonin 2a (5-HT2a) receptor | P28223 | CHEMBL224 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Therapeutic Target | Transferase | TK1 | Thymidine kinase, cytosolic | P04183 | CHEMBL2883 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 49 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT02044341 | Phase 3 Study to Compare the Efficacy and Safety of AR01 to a Placebo Solution for Relief of Pain in Acute Otitis Media | Otitis media | Glycerin (NPC157340) | NP level |
NCT00000556 | Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) | atrial fibrillation | Verapamil (NPC42793) | NP level |
NCT01645709 | Safety, Tolerability, and Efficacy of IA Verapamil in the Treatment of Joint Pain in Subjects With Osteoarthritis of the Knee | osteoarthritis, knee | Verapamil (NPC42793) | NP level |
NCT01575405 | A Study to Compare Three Different Formulations of Tenofovir 1% Gel When Administered Rectally | HIV infection | Glycerin (NPC157340) | NP level |
NCT00243711 | A Multi-Center Randomized Study to Evaluate the Efficacy and Safety of an Investigational Lubricant Eye Drop | dry eye syndrome | Glycerin (NPC157340) | NP level |
NCT00841269 | Oral Uridine for Treatment of Bipolar Depression in Adolescents | bipolar disorder | Uridine (NPC43246) | NP level |
NCT00580606 | A Randomized, Double-Blind Placebo-Controlled Peanut Sublingual Immunotherapy Trial | peanut allergic reaction | Glycerin (NPC157340) | NP level |
NCT00518947 | Pharmacotherapy of Treatment-Resistant Mania | bipolar disorder | Verapamil (NPC42793) | NP level |
NCT03013933 | Brentuximab Vedotin, Cyclosporine, and Verapamil Hydrochloride in Treating Patients With Relapsed or Refractory Hodgkin Lymphoma | Hodgkins lymphoma | Verapamil (NPC42793) | NP level |
NCT01261286 | Drug-Disease Interaction in Crohn's Disease | Crohn's disease | Verapamil (NPC42793) | NP level |
NCT01335386 | Investigation of KLYX in Patients With Constipation | Constipation | Glycerin (NPC157340) | NP level |
NCT01474499 | A Trial of Docusate Sodium and Sorbitol Rectal Solution for the in Patients With Constipation | Constipation | Glycerin (NPC157340) | NP level |
NCT00804895 | Cluster Headache Cortivazol Injection (CHCI) | pain | Verapamil (NPC42793) | NP level |
NCT00691197 | Safety and Acceptability of Using a Rewetting Drop With Contact Lens Wear | Abnormality of refraction | Glycerin (NPC157340) | NP level |
NCT04233034 | Hybrid Closed Loop Therapy and Verapamil for Beta Cell Preservation in New Onset Type 1 Diabetes | type 1 diabetes mellitus | Verapamil (NPC42793) | NP level |
NCT00313157 | RATe Control in Atrial Fibrillation | atrial fibrillation | Verapamil (NPC42793) | NP level |
NCT02823106 | Superselective Citicoline and Verapamil for Ischemic Neuroprotection and Greater Effective Response | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT02772354 | Radiofrequency Ablation of Symptomatic Frequent Ventricular Premature Complexes in Pediatric Population | Ventricular arrhythmia | Verapamil (NPC42793) | NP level |
NCT01687218 | Safety and Acceptability Study of Oral Emtricitabine/Tenofovir Disoproxil Fumarate Tablet and Rectally-Applied Tenofovir Reduced-Glycerin 1% Gel | HIV infection | Glycerin (NPC157340) | NP level |
NCT01575418 | An Exploratory Rectal Safety Study of Three Tenofovir Gel Formulations | HIV infection | Glycerin (NPC157340) | NP level |
NCT00005025 | Gene Therapy in Treating Women With Refractory or Relapsed Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Peritoneal Cancer | fallopian tube cancer;ovarian cancer;peritoneum cancer | Thymidine (NPC71339) | NP level |
NCT02621060 | Effect of Chlorogenic Acid on Patients With Impaired Glucose Tolerance | abnormal glucose tolerance | Chlorogenic Acid (NPC302857) | NP level |
NCT03751592 | Phase Ib/IIa Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Advanced Lung Cancer | lung cancer | Chlorogenic Acid (NPC302857) | NP level |
NCT02372253 | Verapamil for Beta Cell Survival Therapy in Type 1 Diabetes | type 1 diabetes mellitus | Verapamil (NPC42793) | NP level |
NCT02912663 | Magnesium And Verapamil After Recanalization in Ischemia of the Cerebrum: a Clinical and Translational Study. | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT00619203 | Oral Glycerol and High-Dose Rectal Paracetamol to Improve the Prognosis of Childhood Bacterial Meningitis | bacterial meningitis | Glycerin (NPC157340) | NP level |
NCT02136342 | Phase 1 Trial of Chlorogenic Acid in Patients With Advanced Cancer | cancer | Chlorogenic Acid (NPC302857) | NP level |
NCT00003667 | Combination Chemotherapy and Biological Therapy in Treating Patients With High-Risk Ewing's Sarcoma | sarcoma | Glycerin (NPC157340) | NP level |
NCT02728349 | Tolerance and Pharmacokinetic Study of Chlorogenic Acid to Advanced Glioblastoma | glioblastoma multiforme | Chlorogenic Acid (NPC302857) | NP level |
NCT02235558 | Superselective Administration of VErapamil During Recanalization in Acute Ischemic Stroke | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT00533195 | Comparison of UVA1 Phototherapy Versus Photochemotherapy for Patients With Severe Generalized Atopic Dermatitis | atopic eczema | Bergapten (NPC74539) | NP level |
NCT02936830 | Effectiveness of Nanohydroxyapetite Paste on Reducing Dentin Hypersensitivity | allergic disease | Glycerin (NPC157340) | NP level |
NCT03347786 | Verapamil for Neuroprotection in Stroke | Ischemic stroke | Verapamil (NPC42793) | NP level |
NCT00589303 | AV Node Ablation and Pacemaker Therapy Compared to Drug Therapy for Atrial Fibrillation - Pilot Study | atrial fibrillation;heart failure | Verapamil (NPC42793) | NP level |
NCT02110810 | Indomethacin Decreases Post-ERCP Pancreatitis | acute pancreatitis | Glycerin (NPC157340) | NP level |
NCT04356196 | Comparative Study Between the Efficacy of Verapamil and Bisoprolol on Reduction of Bleeding During Endoscopic Sinus Surgery Under General Anaesthesia. | hemorrhage | Verapamil (NPC42793) | NP level |
NCT03782662 | Drug Interaction Study With RV521 in Healthy Volunteer Subjects | Respiratory Syncytial Virus Infection | Verapamil (NPC42793) | NP level |
NCT03901144 | A NOVel Moisturiser for Atopic Dermatitis: Effect on the Skin Barrier | atopic eczema | Glycerin (NPC157340) | NP level |
NCT00210080 | A Study to Diagnose Lung Cancer by Sputum Cytology (01-312) | lung cancer | Uridine (NPC43246) | NP level |
NCT04351763 | Amiodarone or Verapamil in COVID-19 Hospitalized Patients With Symptoms | COVID-19 | Verapamil (NPC42793) | NP level |
NCT04545151 | Verapamil SR in Adults With Type 1 Diabetes | type 1 diabetes mellitus | Verapamil (NPC42793) | NP level |
NCT01607073 | Verapamil as Therapy for Children and Young Adults With Dravet Syndrome | Dravet syndrome | Verapamil (NPC42793) | NP level |
NCT02209155 | R-Verapamil for the Prophylaxis of Episodic Cluster Headache | pain | Verapamil (NPC42793) | NP level |
NCT00322764 | Phase II Study to Assess RG2417 in the Treatment of Bipolar I Depression | bipolar disorder | Uridine (NPC43246) | NP level |
NCT00593463 | Drug Discrimination in Methadone-Maintained Humans Study 1 | drug dependence | Verapamil (NPC42793) | NP level |
NCT02245204 | Phase I Studies of Chlorogenic Acid for Injection for Tolerance and Pharmacokinetic of Advanced Cancers | cancer | Chlorogenic Acid (NPC302857) | NP level |
NCT00841256 | Multicenter Trial of Sublingual Immunotherapy With a Solution of Grass Pollen Allergen Extract in Children | allergic conjunctivitis | Glycerin (NPC157340) | NP level |
NCT03758014 | Studies of Chlorogenic Acid for Injection for Safety and Efficacy of Grade IV GBM Patients | glioblastoma multiforme | Chlorogenic Acid (NPC302857) | NP level |
NCT03296800 | Study to Evaluate Effects of Probenecid, Rifampin and Verapamil on Bexagliflozin in Healthy Subjects | type 2 diabetes mellitus | Verapamil (NPC42793) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
CACNA1C,LMNA,CA9,ADRA2A,CA12,AKR1B1,F10,TK1,HTR2B
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
CACNA1F,HTR2A,LMNA,CA9,ADRA2A,CA12,ALOX15,TK1,ABCB1
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
CACNA1F,HTR2C,CYP1A2,CDA,CA9,CA12,ALOX15,KCNH2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
HTR2C,CDA,CA9,ADRA2A,CA12,KCNH2,TK1,HTR2B
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
KCNH2,ADRA2A,SLC6A4,HTR2C,AKR1B1
NCT00804895,NCT02209155 |
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
HTR2C,HTR2B,F10,ADRA2A,SLC6A4,DRD3,HTR2A
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
CACNA1F,HTR2A,CACNA1C,CDA,ADRA2A,F10,MAPT
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HTR2A,HTR2C,ALOX15,CA9,AKR1B1,KCNH2,MAPT
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
HTR2C,CA9,ADRA2A,CA12,KCNH2,F10,TK1
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
ABCB1,TK1,CA12,DRD3,CDA,CA9
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
HTR2A,SLC6A4,HTR2C,CACNA1C,DRD3,MAPT
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
ADRA2A,DRD3,HTR2C,HTR2B,SLC6A4,HTR2A
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
SLC6A4,CACNA1C,CA12,AKR1B1,KCNH2,TK1
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
SLC6A4,HTR2C,CA9,CA12,KCNH2,TK1
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
SLC6A4,CYP1A2,CDA,CYP1A1,CA12,KCNH2
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
MAPT,SLC6A4,DRD3,HTR2C,HTR2A
|
Bipolar disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60 |
DRD3,HTR2A
NCT00322764,NCT00518947,NCT00841269 |
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
HTR2A,AKR1B1,SLC6A4,HTR2C,DRD3
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
SLC6A4,HTR2C,ALOX15,CA9,AKR1B1
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
TK1,HTR2C,CYP1A2,CA9,AKR1B1
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
HTR2C,CA9,CYP1A1,ALOX15,TK1
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
ABCG2,HTR2C,CDA,CA12,AKR1B1
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
NCT02823106,NCT02912663,NCT03347786,NCT02235558
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
CA9,KCNH2,CACNA1F,CA9
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
HTR2C,CA9,CA12,TK1
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
HTR2C,CA9,CA12,TK1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ALOX15,KCNH2,CYP1A1,ABCB1
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
HTR2A,HTR2C,AKR1B1
|
AnxietyDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB24.3 |
HTR2C,HTR2A,SLC6A4
|
Sleep-wake disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7B2Z |
KCNH2,HTR2A,HTR2C
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
SLC6A4,ADRA2A,HTR2C
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
HTR2B,HTR2C,HTR2A
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
HTR2A,HTR2B,HTR2C
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
ABCB1
NCT03751592,NCT00210080 |
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT04545151,NCT02372253,NCT04233034
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT00000556,NCT00313157,NCT00589303
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT01687218,NCT01575418,NCT01575405
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
TK1,HTR2C,CA9
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
HTR2C,CA9,CYP1A1
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
HTR2C,KCNH2,ABCG2
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
LMNA,F10,ADRA2A
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
CDA,ALOX15,TK1
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
SLC6A4,HTR2A,ABCG2
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CA9,CA12,LMNA
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
HTR2C,SLC6A4
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
HTR2A,SLC6A4
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
F10,AKR1B1
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
AKR1B1,ABCG2
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA12,ABCB1
|
MigraineDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A80 |
SLC6A4,HTR2C
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
TK1,MAPT
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
HTR2A,AKR1B1
|
Psychoactive substances use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G |
HTR2C,DRD3
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
SLC6A4,HTR2A
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
HTR2A,TK1
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
SLC6A4,HTR2A
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
F10,HTR2A
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
HTR2A,TK1
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
CA9,DRD3
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
HTR2A
NCT03296800 |
Chronic insomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00 |
HTR2A,HTR2C
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
KCNH2
NCT00589303 |
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
DRD3,HTR2A
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
CA12,CA9
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT02245204,NCT02136342
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NCT03901144,NCT00533195
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ConstipationDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME05.0 |
NCT01335386,NCT01474499
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Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT02728349,NCT03758014
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Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
DRD3,ABCG2
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Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
HTR2C,ALOX15
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Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
ADRA2A,CYP1A1
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Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CA9,CYP1A1
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Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
CA12,CDA
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
HTR2A,HTR2B
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Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
HTR2A,ABCG2,KCNH2,CACNA1C,HTR2B,CA9,ALOX15,LMNA,F10,TK1,ABCB1
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
TK1,HTR2C,CA9,CA12,KCNH2,MAPT,TK1,CA9,CA12,KCNH2,MAPT
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
SLC6A4,CACNA1F,TK1,CACNA1C,LMNA,CA9,ADRA2A,AKR1B1,KCNH2,MAPT
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Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA12
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Deep vein thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD71 |
F10
|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
HTR2C
|
Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
SLC6A4
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Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
DRD3
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Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F10
|
Opioid use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C43 |
ADRA2A
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Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
SLC6A4
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CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
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Tonus and reflex abnormalityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB47 |
HTR2C
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Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
HTR2B
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Cocaine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C45 |
SLC6A4
|
Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F10
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Human immunodeficiency virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C60-1C62 |
TK1
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
DRD3
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Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
HTR2A
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Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
MAPT
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concerning food/fluid intake symptomDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG43 |
SLC6A4
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General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
SLC6A4
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Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
DRD3
|
Gastroduodenal motor/secretory disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41 |
DRD3
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
ABCG2
|
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
DRD3
|
Blood-forming organ diseaseDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3C0Z |
F10
|
Venous thromboembolismDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD72 |
F10
|
ZosterDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E91 |
TK1
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
DRD3
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
TK1
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
AKR1B1
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
HTR2A
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
SLC6A4
|
Binge eating disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B82 |
SLC6A4
|
Soft tissue disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB56 |
SLC6A4
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
CA9
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
DRD3
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
SLC6A4
|
Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F10
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
HTR2A
|
Ejaculatory dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA03 |
SLC6A4
|
Corneal diseaseDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A76-9A78 |
SLC6A4
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
KCNH2
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Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
SLC6A4
|
Christmas diseaseDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B11 |
F10
|
Supraventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81 |
F10
|
Acute upper respiratory infectionDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA07 |
DRD3
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
MAPT
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
TK1
|
Schizoaffective disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A21 |
HTR2A
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Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
HTR2A
|
Orthostatic hypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA21 |
SLC6A4
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Social anxiety disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B04 |
HTR2A
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
TK1
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
KCNH2
|
Malignant neoplasms of retroperitoneumDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C50 |
NCT00005025
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Unknown or unspecified psychoactive substance dependence, substance and state of remission unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4G.2Z |
NCT00593463
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Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
NCT00003667
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Osteoarthritis of kneeDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA01 |
NCT01645709
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Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
NCT00005025
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NCT02936830
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Ventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC71 |
NCT02772354
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Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
NCT01261286
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Impaired glucose toleranceDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A40.1 |
NCT02621060
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Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
NCT00005025
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Acute pancreatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC31 |
NCT02110810
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Allergic conjunctivitisDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A60.02 |
NCT00841256
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Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT04356196
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Dravet syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61.11 |
NCT01607073
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COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04351763
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Hodgkin lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B30 |
NCT03013933
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Pneumonia due to Respiratory syncytial virusDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.11 |
NCT03782662
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Diseases of the visual system, unspecifiedDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9E1Z |
NCT00243711
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Bacterial meningitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D01.0 |
NCT00619203
|
Otitis mediaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA80-AB0Z |
NCT02044341
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Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
CYP1A1
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Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
CA12
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
AKR1B1
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Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
HTR2A
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Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
ABCG2
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
ALOX15
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
CYP1A1
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Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
TK1
|