Antiphlogistic; Depurative; Diuretic; Febrifuge; Lenitive; Lithontripic; Pectoral; Sedative
Canada; Afghanistan; Madagascar; Italy; Peru; Costa Rica; Cambodia; France; Ethiopia; Netherlands; Ireland; Bolivia; Norway; Ecuador; Australia; Iran; Algeria; El Salvador; Iceland; Venezuela; Guatemala; Zimbabwe; China; Belgium; Germany; Haiti; Iraq; Tanzania; Spain; Ukraine; Georgia; Uganda; Denmark; Poland; Finland; Turkey; Mauritius; Morocco; Sweden; Belarus; Kenya; Switzerland; New Zealand; Russia; Bulgaria; United States; Romania; Albania; Honduras; Portugal; Mexico; Tunisia; South Africa; India; United Kingdom; Austria; Rwanda; Colombia; Greece; Burundi; Hungary; Taiwan; Cyprus
Ingredient ID: NPC98163
Ingredient ID: NPC95716
Ingredient ID: NPC93542
Ingredient ID: NPC92985
Ingredient ID: NPC90371
Ingredient ID: NPC86412
Ingredient ID: NPC84019
Ingredient ID: NPC72670
Ingredient ID: NPC71413
Ingredient ID: NPC67956
Ingredient ID: NPC52063
Ingredient ID: NPC483363
Ingredient ID: NPC483362
Ingredient ID: NPC483361
Ingredient ID: NPC483360
Ingredient ID: NPC483359
Ingredient ID: NPC46940
Ingredient ID: NPC45965
Ingredient ID: NPC41233
Ingredient ID: NPC33294
Ingredient ID: NPC31152
Ingredient ID: NPC310099
Ingredient ID: NPC309367
Ingredient ID: NPC309203
Ingredient ID: NPC29980
Ingredient ID: NPC299625
Ingredient ID: NPC289758
Ingredient ID: NPC288983
Ingredient ID: NPC286815
Ingredient ID: NPC286295
Ingredient ID: NPC283274
Ingredient ID: NPC282633
Ingredient ID: NPC280246
Ingredient ID: NPC271322
Ingredient ID: NPC270088
Ingredient ID: NPC267317
Ingredient ID: NPC261021
Ingredient ID: NPC258501
Ingredient ID: NPC255253
Ingredient ID: NPC247681
Ingredient ID: NPC233533
Ingredient ID: NPC232615
Ingredient ID: NPC219913
Ingredient ID: NPC209054
Ingredient ID: NPC196434
Ingredient ID: NPC182933
Ingredient ID: NPC180058
Ingredient ID: NPC176017
Ingredient ID: NPC168624
Ingredient ID: NPC161480
Ingredient ID: NPC160054
Ingredient ID: NPC152451
Ingredient ID: NPC145879
Ingredient ID: NPC145151
Ingredient ID: NPC138993
Ingredient ID: NPC136699
Ingredient ID: NPC134700
Ingredient ID: NPC134546
Ingredient ID: NPC130730
Ingredient ID: NPC11311
Ingredient ID: NPC107102
Ingredient ID: NPC103497
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Enzyme | HPGD | 15-hydroxyprostaglandin dehydrogenase [NAD+] | P15428 | CHEMBL1293255 |
Therapeutic Target | Hydrolase | MGLL | Monoglyceride lipase | Q99685 | CHEMBL4191 |
Therapeutic Target | Isomerase | EBP | 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase | Q15125 | CHEMBL4931 |
Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
Therapeutic Target | Lyase | CA9 | Carbonic anhydrase IX | Q16790 | CHEMBL3594 |
Therapeutic Target | Membrane receptor | SIGMAR1 | Sigma opioid receptor | Q99720 | CHEMBL287 |
Therapeutic Target | Methyl-lysine/arginine binding protein | L3MBTL1 | Lethal(3)malignant brain tumor-like protein 1 | Q9Y468 | CHEMBL1287622 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR1 | Estrogen receptor alpha | P03372 | CHEMBL206 |
Therapeutic Target | Nuclear hormone receptor subfamily 3 | ESR2 | Estrogen receptor beta | Q92731 | CHEMBL242 |
Therapeutic Target | Other nuclear protein | MDM2 | p53-binding protein Mdm-2 | Q00987 | CHEMBL5023 |
Therapeutic Target | Oxidoreductase | ALDH1A1 | Aldehyde dehydrogenase 1A1 | P00352 | CHEMBL3577 |
Therapeutic Target | Oxidoreductase | ALOX15 | Arachidonate 15-lipoxygenase | P16050 | CHEMBL2903 |
Therapeutic Target | Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
Drug Transporter | Potassium channels | KCNH2 | HERG | Q12809 | CHEMBL240 |
Therapeutic Target | Protein Kinase | JAK2 | Tyrosine-protein kinase JAK2 | O60674 | CHEMBL2971 |
Therapeutic Target | Protein methyltransferase | EHMT2 | Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 | Q96KQ7 | CHEMBL6032 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 130 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT03024814 | Prophylactic Acetaminophen for Prevention Intraventricular Hemorrhage in Premature Infants | hemorrhage | Glucose, Liquid (NPC289758) | NP level |
NCT01883531 | Crossover Trial Determining the Efficacy of Dry Powder Mannitol to Improve Lung Function in Subjects Aged 6-17 Years | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT00303849 | Carboplatin, Melphalan, Etoposide Phosphate, Mannitol, and Sodium Thiosulfate in Treating Patients With Previously Treated Brain Tumors | anaplastic oligodendroglioma | Mannitol (NPC86412) | NP level |
NCT03887169 | Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. | pulmonary alveolar proteinosis | Methionine (NPC152451) | NP level |
NCT01871766 | Risk-Adapted Focal Proton Beam Radiation and/or Surgery in Patients With Low, Intermediate and High Risk Rhabdomyosarcoma Receiving Standard or Intensified Chemotherapy | rhabdomyosarcoma | Methionine (NPC152451) | NP level |
NCT00810940 | Controlled Trial of ABELADRUG200 in Closed, Severe Head Injury | injury | Mannitol (NPC86412) | NP level |
NCT03994471 | Efficacy and Safety of XyloCore Peritoneal Dialysis Solution. | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
NCT03577730 | Caffeine and Neurologic Recovery Following Surgery and General Anesthesia | pain | Glucose, Liquid (NPC289758) | NP level |
NCT04557878 | Role of Liquid Phase Concentrated Growth Factors vs. Hypertonic Dextrose Prolotherapy for Management of Patients With Disc Displacement Without Reduction | temporomandibular joint disorder | Glucose, Liquid (NPC289758) | NP level |
NCT03778593 | FOLFIRINOX for 2nd-line Treatment of BTC | biliary tract cancer | Glucose, Liquid (NPC289758) | NP level |
NCT04726436 | Dextrose Effect on Postoperative Nausea and Vomiting (PONV) | post operative nausea and vomiting | Glucose, Liquid (NPC289758) | NP level |
NCT00792714 | Pharmacokinetics of Inhaled Mannitol in Cystic Fibrosis Patients | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT02325583 | Intraoral 30% Glucose Effect In Newborns | epilepsy | Glucose, Liquid (NPC289758) | NP level |
NCT04394143 | Effect of AD128 to Treat Obstructive Sleep Apnea | obstructive sleep apnea | Mannitol (NPC86412) | NP level |
NCT03690583 | Immunomodulation by Zinc Supplementation in Children With Pneumonia | pneumonia | Glucose, Liquid (NPC289758) | NP level |
NCT04217421 | Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass | congenital heart disease | Mannitol (NPC86412) | NP level |
NCT00475176 | S-Adenosyl Methionine (SAMe) to Treat Patients With Chronic Hepatitis C | chronic hepatitis C virus infection | Methionine (NPC152451) | NP level |
NCT02054325 | Study Protocol Comparing Polidocanol Versus Hypertonic Glucose for Treatment of Reticular Veins | Varicose veins | Glucose, Liquid (NPC289758) | NP level |
NCT00630812 | Long Term Administration of Inhaled Mannitol in Cystic Fibrosis | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT02484170 | Mannitol Cream for Post Herpetic Neuralgia | postherpetic neuralgia | Mannitol (NPC86412) | NP level |
NCT01753882 | Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI) | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
NCT01076491 | High Dose Inhaled Mannitol Study | Bronchiectasis | Mannitol (NPC86412) | NP level |
NCT01210183 | Biological Response of Stage IV Knee Osteoarthritis to Serial 12.5% Dextrose | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
NCT00113854 | Mannitol as Adjunct Therapy for Childhood Cerebral Malaria | malaria | Mannitol (NPC86412) | NP level |
NCT04677829 | Safety and Tolerability of PNT001 in Patients With Acute Traumatic Brain Injury (TBI) | brain injury | Glucose, Liquid (NPC289758) | NP level |
NCT01788969 | Serotonergic Modulation of Motor Function in Subacute and Chronic SCI | Spinal cord injury | Glucose, Liquid (NPC289758) | NP level |
NCT01140646 | Evaluation of SAMe for Hot Flashes | Hot flashes | Methionine (NPC152451) | NP level |
NCT03337477 | A Study to Evaluate a Potassium Normalization Treatment Regimen Including Sodium Zirconium Cyclosilicate (ZS) Among Patients With S-K ≥5.8 | Hyperkalemia | Glucose, Liquid (NPC289758) | NP level |
NCT02591927 | Reappraisal of GIK in Acute STEMI by Pre-hospital Administration | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
NCT02752308 | Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair | hypospadias | Glucose, Liquid (NPC289758) | NP level |
NCT01557296 | Evaluation of Diagnostic Methods and Dietary Treatment of Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
NCT02125786 | A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma | ependymoma | Methionine (NPC152451) | NP level |
NCT04870073 | Retrograde Autologous Priming and Mannitol for Reducing Hemodilution in Cardiac Surgery | coronary artery disease | Mannitol (NPC86412) | NP level |
NCT01843088 | Trial of Mannitol Cream for Pain Relief After a Long Run | pain | Mannitol (NPC86412) | NP level |
NCT00573313 | Effects of SAMe in Patients With Alcoholic Liver Disease | liver disease | Methionine (NPC152451) | NP level |
NCT03357666 | Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis | bacterial vaginosis | Glucose, Liquid (NPC289758) | NP level |
NCT02586285 | Effect of S-Adenosyl Methionine Treatment on Recurrence After Curative Resection of Hepatocellular Carcinoma | hepatocellular carcinoma | Methionine (NPC152451) | NP level |
NCT00632775 | 0.9% NaCl/Dextrose 5% vs 0.45% NaCl/Dextrose 5% as Maintenance Intravenous Fluids in Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
NCT01419067 | A Phase II Trial of Limited Surgery and Proton Therapy for Craniopharyngioma or Observation After Radical Resection | Craniopharyngioma | Methionine (NPC152451) | NP level |
NCT04133922 | Effect of GLP-1 on Microvascular Insulin Responses in Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT00108589 | S-Adenosylmethionine Therapy for Non-Alcoholic Steatohepatitis | Hepatitis | Methionine (NPC152451) | NP level |
NCT05160532 | Intraarticular Dextrose Prolotherapy for Symptomatic Knee Osteoarthritis | osteoarthritis | Glucose, Liquid (NPC289758) | NP level |
NCT05185999 | Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
NCT00277537 | Safety and Efficacy of Bronchitol in Bronchiectasis | Bronchiectasis | Mannitol (NPC86412) | NP level |
NCT01520207 | Mannitol - Potential Role in Hemodialysis Initiation for Reduction of Intra-dialytic Hypotension | hypotension | Mannitol (NPC86412) | NP level |
NCT00612014 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
NCT01251770 | Variation in Natremia Using Two Different Maintenance Intravenous Fluids in Postsurgical Hospitalized Children | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
NCT00062972 | Improving Memory in Patients With Multiple Sclerosis | multiple sclerosis | Glucose, Liquid (NPC289758) | NP level |
NCT02632630 | Nutrition Supplementation in Hospitalized Patients | malnutrition | Glucose, Liquid (NPC289758) | NP level |
NCT02596477 | Evaluation of Vepoloxamer in Chronic Heart Failure | heart failure | Glucose, Liquid (NPC289758) | NP level |
NCT01345474 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
NCT00251056 | Mannitol Dose Response Study in Cystic Fibrosis | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT03241706 | Liver Glycogen and Hypoglycemia in Humans | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
NCT00639808 | Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Diabetic Gastroparesis | gastroparesis | Glucose, Liquid (NPC289758) | NP level |
NCT02185729 | Comparing Soybean Oil-Based (Intralipid) With an Olive Oil-Based (ClinOleic) Lipid Emulsion on Healthy Volunteers | metabolic disease | Glucose, Liquid (NPC289758) | NP level |
NCT04385264 | COVID-19 | Mannitol (NPC86412) | NP level | |
NCT00446667 | A Pilot Safety Study of Inhaled Dry Powder Mannitol in Acute Exacerbations of COPD | chronic obstructive pulmonary disease | Mannitol (NPC86412) | NP level |
NCT01548612 | Add-on Sodium Nitroprusside to Treatment as Usual in Schizophrenia | schizophrenia | Glucose, Liquid (NPC289758) | NP level |
NCT02728687 | Topical Menthol +/- Mannitol for Painful Diabetic Peripheral Neuropathy | diabetic neuropathy | Mannitol (NPC86412) | NP level |
NCT00337597 | Continuous Regional Analgesia After Total Knee Arthroplasty | pain | Glucose, Liquid (NPC289758) | NP level |
NCT01307904 | The Glycemic Indices of Five Common Varieties of Dates in the Tested Among Healthy and Diabetic Subjects | diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT00686608 | Hypothalamic Functional Magnetic Resonance Imaging (fMRI) Response to Nutrients | obesity | Glucose, Liquid (NPC289758) | NP level |
NCT05305508 | Assessment of the Efficacy of Calcium Dobesilate vs. Placebo on SARS-CoV-2 Viral Load Amongst Outpatients With COVID-19. | COVID-19 | Mannitol (NPC86412) | NP level |
NCT01075984 | Pharmacokinetics, Safety, and Tolerability of Intravenous Posaconazole Solution Followed by Oral Posaconazole Suspension in Subjects at High Risk for Invasive Fungal Infections (P05520) | fungal infectious disease | Glucose, Liquid (NPC289758) | NP level |
NCT02910518 | A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique, in Patients With Type 1 Diabetes Mellitus | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT00617981 | Phase 3 Study of ThermoDox With Radiofrequency Ablation (RFA) in Treatment of Hepatocellular Carcinoma (HCC) | hepatocellular carcinoma | Glucose, Liquid (NPC289758) | NP level |
NCT04409665 | The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST) | respiratory failure | Glucose, Liquid (NPC289758) | NP level |
NCT03749408 | Effect of Addition of Mannitol to Bupivacaine on IANB Success and Post-endodontic Pain | pulpitis | Mannitol (NPC86412) | NP level |
NCT01883440 | Glucose Oxidase as Treatment Against Common Cold | common cold | Glucose, Liquid (NPC289758) | NP level |
NCT00823108 | Rapid Administration of Insulin in Sepsis | septic shock | Glucose, Liquid (NPC289758) | NP level |
NCT03860688 | Effects of Oral Glucose and Teduglutide on Plasma Lipoproteins | hyperlipidemia | Glucose, Liquid (NPC289758) | NP level |
NCT02710266 | Evaluation of the Effect of Gabexate Mesilate in the Hepatocyte Protection After Liver Resection | liver disease | Glucose, Liquid (NPC289758) | NP level |
NCT00091507 | IMMEDIATE Trial - Out of Hospital Administration of Glucose, Insulin and Potassium. | congestive heart failure;intermediate coronary syndrome;myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
NCT04534465 | Study to Gather Information on the Acceptability of a New Flavor System With Increasing Levels of 2, 4, 6 g or Higher of Mannitol for PEG 3350 in Subjects Having Infrequent Bowel Movements. | Constipation | Mannitol (NPC86412) | NP level |
NCT03573999 | Effect of Mannitol 20% Versus Hypertonic Saline 7.5% in Brain Metabolism and Oxygenation | brain edema | Mannitol (NPC86412) | NP level |
NCT04001036 | Efficacy and Safety Assessments of a Peritoneal Dialysis Solution Containing Glucose, Xylitol, and L-Carnitine in CAPD | chronic kidney disease | Glucose, Liquid (NPC289758) | NP level |
NCT03418935 | Remaxol® in Mechanical Jaundice of Non-malignant Origin | obstructive jaundice | Methionine (NPC152451) | NP level |
NCT01547364 | Caudal Epidural Injection of Dextrose For Low Back Pain | Low back pain | Glucose, Liquid (NPC289758) | NP level |
NCT03205553 | Direct Peritoneal Resuscitation in Gastroschisis | gastroschisis | Glucose, Liquid (NPC289758) | NP level |
NCT01028339 | Mannitol vs HS to Treat ICHT After Severe TBI : Comparison on PtiO2 and Microdialysis Values | brain injury | Mannitol (NPC86412) | NP level |
NCT00835939 | Treatment for Achilles Tendinopathy | Tendinopathy | Glucose, Liquid (NPC289758) | NP level |
NCT00617552 | Safety and Efficacy of IV Infusion of TZP-101 for POI After Major Open Abdominal Surgery | ileus | Glucose, Liquid (NPC289758) | NP level |
NCT02180412 | Controlled Trial of Panhematin in Treatment of Acute Attacks of Porphyria | porphyria | Glucose, Liquid (NPC289758) | NP level |
NCT02269735 | A Three-part Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of MK-2640 in Healthy Participants (Part I) and Participants With Type 1 Diabetes Mellitus (Parts II and III) (MK-2640-001) | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT04088591 | High-dose Intravenous Vitamin C as an Adjunctive Treatment for Sepsis in Rwanda | Sepsis | Glucose, Liquid (NPC289758) | NP level |
NCT04832009 | Reversing Glucose and Lipid-mediated Vascular Dysfunction | hypertension | Glucose, Liquid (NPC289758) | NP level |
NCT04918719 | Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke | Ischemic stroke | Glucose, Liquid (NPC289758) | NP level |
NCT01142505 | Wheeze and Intermittent Treatment | wheezing | Mannitol (NPC86412) | NP level |
NCT01121354 | Pharmacokinetics and Safety of Cefazolin 2g in DUPLEX | infection | Glucose, Liquid (NPC289758) | NP level |
NCT02866435 | Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes | Hypoglycemia | Glucose, Liquid (NPC289758) | NP level |
NCT01223690 | Clarithromycin as Immunomodulator for the Management of Sepsis | Sepsis;septic shock | Glucose, Liquid (NPC289758) | NP level |
NCT01718964 | Acute Effects of Cortisol on Heroin Craving in Opioid Dependence (Ghost-Basel) | opioid dependence | Mannitol (NPC86412) | NP level |
NCT00189007 | Antenatal Allopurinol During Fetal Hypoxia | fetal hypoxia | Mannitol (NPC86412) | NP level |
NCT03636971 | Gait Analysis Following Knee Viscosupplementation | osteoarthritis | Mannitol (NPC86412) | NP level |
NCT01887197 | Repeatability and Response Study of Absorptive Clearance Scans | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT00446680 | Long Term Administration of Inhaled Dry Powder Mannitol In Cystic Fibrosis - A Safety and Efficacy Study | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT02903355 | Phase 3 Clinical Trial: D-methionine to Reduce Noise-Induced Hearing Loss (NIHL) | noise-induced hearing loss | Methionine (NPC152451) | NP level |
NCT00694564 | Evaluation of S-adenosyl Methionine (SAM-e) for Recurrent Abdominal Pain in Children | Abdominal pain | Methionine (NPC152451) | NP level |
NCT03039673 | MIROCALS: Modifying Immune Response and OutComes in ALS | amyotrophic lateral sclerosis | Glucose, Liquid (NPC289758) | NP level |
NCT05029037 | High-dose Intravenous Vitamin C (HDIVC) as Adjuvant Therapy in Critical Patients With Positive COVID-19. A Pilot Randomized Controlled Dose-comparison Trial. | COVID-19 | Glucose, Liquid (NPC289758) | NP level |
NCT00552786 | Antioxidation Medication for Noise-induced Hearing Loss | hearing loss | Glucose, Liquid (NPC289758) | NP level |
NCT00730977 | A Pilot Study to Investigate Administration of Mannitol Via a Novel Dry Powder Inhaler Device | Bronchiectasis | Mannitol (NPC86412) | NP level |
NCT00569088 | Study of the Pathogenesis and Molecular Mechanism of "YURE" in Internal Intractable Diseases | stroke | Mannitol (NPC86412) | NP level |
NCT01909336 | Use of Isotonic Solutions Versus Hypotonic Solutions for Preventing Hospital Acquired Hyponatremia | Hyponatremia | Glucose, Liquid (NPC289758) | NP level |
NCT01606787 | Mannitol Use During Partial Nephrectomy Prior to Renal Ischemia and Impact on Renal Function Outcomes | kidney cancer | Mannitol (NPC86412) | NP level |
NCT04488874 | Sodium Lactate and Brain Relaxation (LSD) | intracranial hypertension | Mannitol (NPC86412) | NP level |
NCT00455130 | A Phase 2 Study to Determine the Safety and Efficacy of Inhaled Dry Powder Mannitol in Cystic Fibrosis | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT00117208 | Comparison of Inhaled Mannitol and rhDNase in Children With Cystic Fibrosis | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT05424315 | Impact of DApagliflozin on Cardiac Function Following Anterior Myocardial Infarction in Non-Diabetic Patients | myocardial infarction | Glucose, Liquid (NPC289758) | NP level |
NCT00800085 | Beta Cell Function in (Pre) Type 1 Diabetes | type 1 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT03747679 | Palatability (Taste) of Oral Formulations of Bosutinib | chronic myelogenous leukemia | Mannitol (NPC86412) | NP level |
NCT01485315 | Transfusion-requirements in Septic Shock Trial | septic shock | Glucose, Liquid (NPC289758);Mannitol (NPC86412) | NP level |
NCT05129748 | Efficacy of Sodium Thiosulfate and Mannitol in Reducing Ototoxicity in Adult Patients Receiving Cisplatin Chemotherapy | hearing loss | Mannitol (NPC86412) | NP level |
NCT02319512 | Effects of Chewing Gum Against Postoperative Ileus | ileus | Glucose, Liquid (NPC289758) | NP level |
NCT04895358 | Study of Pembrolizumab (MK-3475) Plus Chemotherapy Versus Placebo Plus Chemotherapy for HR+/HER2- Locally Recurrent Inoperable or Metastatic Breast Cancer (MK-3475-B49/KEYNOTE-B49) | breast neoplasm | Glucose, Liquid (NPC289758) | NP level |
NCT05205486 | Pharmacokinetics and Safety of Cefazolin 3gm DUPLEX in Adults | infection | Glucose, Liquid (NPC289758) | NP level |
NCT04791202 | Hypertonic Dextrose Versus Corticosteroid Intra-Articular Injections for the Treatment of Trapeziometacarpal Arthritis | pain | Glucose, Liquid (NPC289758) | NP level |
NCT02037815 | Correlation of Measured and Calculated Serum Osmolality During Hyperosmolar Drugs Infusion in Patients After Craniotomy | brain edema | Mannitol (NPC86412) | NP level |
NCT02728037 | Magnesium-Based Trigger Point Injections for Relief of Chronic Myofascial Pelvic Pain | pain | Glucose, Liquid (NPC289758) | NP level |
NCT02570971 | Mannitol Versus Supportive Care in Ciguatera Fish Poisoning | ciguatera poisoning | Mannitol (NPC86412) | NP level |
NCT02374281 | Autonomic Nervous System Reactivity of the Newborn After a Nociceptive Stress: Interest of Sucrose and Non-nutritive Sucking | pain | Glucose, Liquid (NPC289758) | NP level |
NCT00213759 | Prevention Trial of Nosocomial Infections in Neutropenic Prematures With G-CSF | neutropenia | Glucose, Liquid (NPC289758) | NP level |
NCT00359697 | Comparison of Two Different Medications Used to Treat Elevated Intracranial Pressure | intracranial hypertension | Mannitol (NPC86412) | NP level |
NCT02678208 | The Effect of Tranexamic Acid on Uterine Blood Flow After Vaginal Delivery | postpartum hemorrhage | Glucose, Liquid (NPC289758) | NP level |
NCT02134353 | A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects | cystic fibrosis | Mannitol (NPC86412) | NP level |
NCT05326763 | Functional and Electromyographical Changes After PRP or Dextrose Injection in Chronic Lateral Epicondylitis | lateral epicondylitis | Glucose, Liquid (NPC289758) | NP level |
NCT01300260 | Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose | type 2 diabetes mellitus | Glucose, Liquid (NPC289758) | NP level |
NCT02861898 | Super-selective Intra-arterial Repeated Infusion of Cetuximab for the Treatment of Newly Diagnosed Glioblastoma | brain cancer;glioblastoma multiforme | Mannitol (NPC86412) | NP level |
NCT00669331 | Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis | Bronchiectasis | Mannitol (NPC86412) | NP level |
NCT01233492 | Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme | Central Nervous System Neoplasm | Mannitol (NPC86412) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
L3MBTL1,ESR2,EHMT2,LMNA,MAPT,CA9,KCNH2,LOXL2,LOXL4
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
SIGMAR1,KCNH2
NCT00337597,NCT02728037,NCT04791202,NCT02374281,NCT03577730,NCT01843088 |
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
LMNA,ALOX15,MDM2,CA9,HPGD,LOXL2,SIGMAR1,LOXL4
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HSD17B10,ALOX15,CA2,EBP,CA9,LOXL2,NPSR1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B10,ALOX15,MAPT,EBP,CA9,KCNH2,HPGD
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
ALOX15,CA2,EBP,KCNH2,HPGD,ESR2
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
LOXL3,EBP,CA9,KCNH2,HPGD,LOXL2
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
ESR1,JAK2,MDM2,CA2,CA9
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
ESR1,CA9,CA2,ESR2,JAK2
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
EBP,MDM2,HPGD,MGLL,NPSR1
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
ESR1,JAK2,KCNH2
NCT00062972 |
BronchiectasisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA24 |
NCT00669331,NCT00730977,NCT00277537,NCT01076491
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT00800085,NCT04133922,NCT02910518,NCT02269735
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
MAPT,LOXL3,CA2,LOXL2
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
L3MBTL1,KCNH2,LOXL2,LOXL4
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
CA9,KCNH2,CA9,LOXL2
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
CA9,KCNH2,LOXL2,NPSR1
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
ALOX15,CA2,CA9,NPSR1
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
LMNA,CA2,CA9,LOXL4
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
ESR1,LOXL3,LOXL2,LOXL4
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
MAPT,SIGMAR1,ESR2
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
KCNH2,CA2
NCT02596477 |
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
ESR1,ESR2,MDM2
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
EBP,JAK2,CA2
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
ESR2
NCT01223690,NCT04088591 |
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT02591927,NCT05424315,NCT00091507
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT01210183,NCT03636971,NCT05160532
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
NCT05185999,NCT04001036,NCT03994471
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT05029037,NCT04385264,NCT05305508
|
GastroparesisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA41.00 |
NCT00639808,NCT01557296,NCT00612014
|
Hypo-kalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C77 |
NCT01251770,NCT01909336,NCT00632775
|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT01223690,NCT00823108,NCT01485315
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
CA9,LOXL2,NPSR1
|
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
ALDH1A1,KCNH2,MDM2
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
ALOX15,NPSR1,LOXL2
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
ESR1,CA9,KCNH2
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
MAPT,SIGMAR1
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
MDM2,JAK2
|
Hyper-lipoproteinaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
ESR1,ESR2
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SIGMAR1,MAPT
|
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
MAPT,MDM2
|
MalariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F40-1F45 |
KCNH2
NCT00113854 |
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
JAK2,MDM2
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
SIGMAR1
NCT00446667 |
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
JAK2,MDM2
|
Menopausal disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA30 |
ESR1,ESR2
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
SIGMAR1
NCT01548612 |
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
ESR1
NCT01307904 |
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
ESR1
NCT02861898 |
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2,ESR1
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
SIGMAR1
NCT01233492 |
Postoperative ileusDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA91-DB30 |
NCT00617552,NCT02319512
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NCT01121354,NCT05205486
|
Injury of spinal cord, level unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51.2 |
NCT01753882,NCT01788969
|
Hearing disorderDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB50-AB57 |
NCT00552786,NCT05129748
|
Intracranial injury, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.Z |
NCT04677829,NCT01028339
|
Hypoglycaemia without associated diabetesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A41 |
NCT03241706,NCT02866435
|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT02586285,NCT00617981
|
Cerebral oedemaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D60.1 |
NCT03573999,NCT02037815
|
Other specified increased intracranial pressureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D60.Y |
NCT04488874,NCT00359697
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB10Z |
NCT02710266,NCT00573313
|
Noise effects on inner earDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AB37 |
NCT02903355,NCT01345474
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
ALOX15,NPSR1
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
CA9,NPSR1
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
CA9,NPSR1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
CA2,LMNA
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
CA2,CA9
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CA2,KCNH2
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
L3MBTL1,EHMT2,MAPT,CA9,KCNH2,LOXL2,EHMT2,MAPT,CA9,KCNH2,LOXL2,LOXL4
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
HTT,HSD17B10,ESR2,EHMT2,LMNA,SIGMAR1,EBP,CA9,MGLL,LOXL4,ALDH1A1
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
SIGMAR1
NCT00117208,NCT00792714,NCT01883531,NCT00455130,NCT00446680,NCT02134353,NCT00630812,NCT01887197,NCT00251056 |
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
EHMT2,SIGMAR1,ALOX15,ESR1,CA2,EBP,CA9,KCNH2,HPGD,MGLL
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
LMNA,ALOX15,LOXL3,CA2,EBP,CA9,KCNH2,LOXL2,LOXL4,NPSR1
|
Female genital tract noninflammatory disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA1Y |
ESR1
|
B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A86 |
JAK2
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA2
|
Skeletal anomalyDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD24 |
ESR1
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
Neurobehavioral disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00-8A0Z |
SIGMAR1
|
SomnolenceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG42 |
SIGMAR1
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
JAK2
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
ESR1
|
VaginitisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA02 |
ESR1
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
ESR1
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
ESR2
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
ESR2
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ALDH1A1
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
JAK2
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
JAK2
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
SIGMAR1
|
Bulimia nervosaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B81 |
SIGMAR1
|
Neuroendocrine carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C34 |
MDM2
|
Male infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB04 |
ESR1
|
Intellectual development disorderDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD90 |
SIGMAR1
|
ThrombocytosisDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B63 |
JAK2
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
MAPT
|
Metastatic tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E2Z |
ESR1
|
Sleep-wake disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7B2Z |
KCNH2
|
Sexual dysfunctionDisease Category: 17.Conditions related to sexual healthDisease ICD-11 Code: HA00-HA01 |
SIGMAR1
|
Epileptic encephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A62 |
SIGMAR1
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
ESR2
|
Female infertilityDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA31 |
ESR1
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
CA9
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
MDM2
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
MGLL
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
ESR1
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
CA2
|
Tic disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A05 |
MGLL
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
JAK2
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA2
|
CoughDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD12 |
SIGMAR1
|
Female pelvic painDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA34 |
ESR1
|
AlopeciaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED70 |
JAK2
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
JAK2
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
SIGMAR1
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
JAK2
|
Menstrual cycle bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20 |
ESR1
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
LOXL2
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
ESR1
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
MDM2
|
Adrenal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
ESR1
|
DyspareuniaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA12 |
ESR1
|
Acquired prion diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E01 |
ESR1
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
|
Breast in situ carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65 |
ESR1
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
CA9
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
SIGMAR1
|
Immune system diseaseDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01-4B41 |
SIGMAR1
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
SIGMAR1
|
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
ESR2
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
ESR2
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
MDM2
|
Postherpetic polyneuropathyDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E91.5 |
NCT02484170
|
PulpitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA09.0 |
NCT03749408
|
HypospadiasDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB53 |
NCT02752308
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
NCT02185729
|
Exposure to or harmful effects of undetermined intent of other or unspecified substances chiefly nonmedicinal as to sourceDisease Category: 23.External causes of morbidity or mortalityDisease ICD-11 Code: PH56 |
NCT02570971
|
Congestive heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10 |
NCT00091507
|
Vaginal dischargeDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF3A |
NCT03357666
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
NCT03778593
|
Obstructive sleep apnoeaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A41 |
NCT04394143
|
Skin fungal infection disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA60 |
NCT01075984
|
ConstipationDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME05.0 |
NCT04534465
|
Rhabdomyosarcoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0GA1 |
NCT01871766
|
Common cold disorder(TM1)Disease Category: 26.Supplementary Chapter Traditional Medicine Conditions - Module IDisease ICD-11 Code: SA60 |
NCT01883440
|
Structural developmental anomaly of heart or great vessels, unspecifiedDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA8Z |
NCT04217421
|
Diseases of the musculoskeletal system or connective tissue, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FC0Z |
NCT00835939
|
GastroschisisDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LB02 |
NCT03205553
|
Respiratory failureDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB41 |
NCT04409665
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT04870073
|
Oligodendroglioma, anaplasticDisease Category: X.Extension CodesDisease ICD-11 Code: XH8844 |
NCT00303849
|
Chronic myeloid leukaemia, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4XG8 |
NCT03747679
|
Opioid use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C43 |
NCT01718964
|
Temporomandibular joint disordersDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0E.8 |
NCT04557878
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
NCT00569088
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT03690583
|
Diabetic polyneuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C03.0 |
NCT02728687
|
HypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA20-BA21 |
NCT01520207
|
WheezingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11.C |
NCT01142505
|
Nausea/vomitingDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD90 |
NCT04726436
|
PolyuriaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MF55 |
NCT02180412
|
Maternal care for signs of fetal hypoxiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA86.2 |
NCT00189007
|
Unstable anginaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40.0 |
NCT00091507
|
Ependymoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1511 |
NCT02125786
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
NCT04832009
|
Postpartum haemorrhageDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA43 |
NCT02678208
|
HyperlipidemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C80 |
NCT03860688
|
Low back painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME84.2 |
NCT01547364
|
Neoplasms of unknown behaviour of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F95 |
NCT04895358
|
Varicose veinsDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD74-BD75 |
NCT02054325
|
Acute viral hepatitisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50 |
NCT00108589
|
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
NCT00686608
|
Haemorrhage, not elsewhere classifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG27 |
NCT03024814
|
Abdominal pelvic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD81 |
NCT00694564
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT02632630
|
HyperkalaemiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C76 |
NCT03337477
|
Flare or flashDisease Category: X.Extension CodesDisease ICD-11 Code: XE03F |
NCT01140646
|
CraniopharyngiomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH1AZ2 |
NCT01419067
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT00475176
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NCT01300260
|
Glioblastoma, primary, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH0MB1 |
NCT02861898
|
Malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
NCT01606787
|
Pulmonary alveolar proteinosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB04.31 |
NCT03887169
|
Obstruction of bile ductDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC10.02 |
NCT03418935
|
NeutropeniaDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4B00 |
NCT00213759
|
Epilepsy/seizureDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A61-8A6Z |
NCT02325583
|
Amyotrophic lateral sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60.0 |
NCT03039673
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
NCT04918719
|
Lateral epicondylitis of elbowDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB55.1 |
NCT05326763
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
NCT00810940
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
JAK2
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
JAK2
|
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
LOXL2
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
HPGD
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
JAK2
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
CA9
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
ALOX15
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CA9
|
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
LOXL4
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
LOXL2
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
EBP
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
HPGD
|
Parkinson diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00.0 |
ALDH1A1
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
MGLL
|