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Collective Molecular Activities of the Plant: Elephantopus Angustifolius


Example Image
PLANiTS DNA barcode

Click for details-----ITS

NA

Click for details-----ITS1

NA

Click for details-----ITS2

NA
Taxonomic Information

Plant ID: NPO11481
Plant Latin Name: Elephantopus Angustifolius
Taxonomy Genus: Elephantopus
Taxonomy Family: Asteraceae

Plant External Links:

NCBI TaxonomyDB: n.a.
Plant-of-the-World-Online: n.a.

Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Compounds Summary

Overview of Ingredients

123 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.


88 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)

18 Ingredients with experimental-derived Activity

Unique ingredients have activity data available.





Ingredient Structrual Cards

Ingredient ID: NPC99964

Ingredient ID: NPC99006

Ingredient ID: NPC98175

Ingredient ID: NPC96337

Ingredient ID: NPC93194

Ingredient ID: NPC91972

Ingredient ID: NPC88603

Ingredient ID: NPC85637

Ingredient ID: NPC82287

Ingredient ID: NPC80692

Ingredient ID: NPC77579

Ingredient ID: NPC75247

Ingredient ID: NPC74758

Ingredient ID: NPC72237

Ingredient ID: NPC68173

Ingredient ID: NPC67532

Ingredient ID: NPC61305

Ingredient ID: NPC61057

Ingredient ID: NPC58959

Ingredient ID: NPC58809

Ingredient ID: NPC55154

Ingredient ID: NPC54199

Ingredient ID: NPC53449

Ingredient ID: NPC52620

Ingredient ID: NPC51920

Ingredient ID: NPC51694

Ingredient ID: NPC49327

Ingredient ID: NPC42150

Ingredient ID: NPC311969

Ingredient ID: NPC307021

Ingredient ID: NPC306551

Ingredient ID: NPC306009

Ingredient ID: NPC305642

Ingredient ID: NPC304373

Ingredient ID: NPC3031

Ingredient ID: NPC301983

Ingredient ID: NPC298934

Ingredient ID: NPC298509

Ingredient ID: NPC297084

Ingredient ID: NPC295534

Ingredient ID: NPC293804

Ingredient ID: NPC292090

Ingredient ID: NPC291186

Ingredient ID: NPC289642

Ingredient ID: NPC286188

Ingredient ID: NPC28583

Ingredient ID: NPC282999

Ingredient ID: NPC280452

Ingredient ID: NPC27744

Ingredient ID: NPC275846

Ingredient ID: NPC273757

Ingredient ID: NPC272256

Ingredient ID: NPC267068

Ingredient ID: NPC260507

Ingredient ID: NPC255467

Ingredient ID: NPC255076

Ingredient ID: NPC255042

Ingredient ID: NPC255027

Ingredient ID: NPC253679

Ingredient ID: NPC253301

Ingredient ID: NPC25317

Ingredient ID: NPC251097

Ingredient ID: NPC251031

Ingredient ID: NPC250563

Ingredient ID: NPC247380

Ingredient ID: NPC246096

Ingredient ID: NPC245419

Ingredient ID: NPC239242

Ingredient ID: NPC234424

Ingredient ID: NPC231276

Ingredient ID: NPC225136

Ingredient ID: NPC220140

Ingredient ID: NPC218298

Ingredient ID: NPC21078

Ingredient ID: NPC209575

Ingredient ID: NPC208485

Ingredient ID: NPC202369

Ingredient ID: NPC199623

Ingredient ID: NPC198272

Ingredient ID: NPC197059

Ingredient ID: NPC196733

Ingredient ID: NPC196333

Ingredient ID: NPC195624

Ingredient ID: NPC195287

Ingredient ID: NPC194465

Ingredient ID: NPC194456

Ingredient ID: NPC189840

Ingredient ID: NPC187217

Ingredient ID: NPC184203

Ingredient ID: NPC18215

Ingredient ID: NPC18205

Ingredient ID: NPC179650

Ingredient ID: NPC179576

Ingredient ID: NPC178799

Ingredient ID: NPC178152

Ingredient ID: NPC174525

Ingredient ID: NPC174406

Ingredient ID: NPC173721

Ingredient ID: NPC173305

Ingredient ID: NPC172112

Ingredient ID: NPC172093

Ingredient ID: NPC164646

Ingredient ID: NPC164498

Ingredient ID: NPC160468

Ingredient ID: NPC157538

Ingredient ID: NPC156461

Ingredient ID: NPC156018

Ingredient ID: NPC145154

Ingredient ID: NPC144916

Ingredient ID: NPC142438

Ingredient ID: NPC140857

Ingredient ID: NPC137739

Ingredient ID: NPC137136

Ingredient ID: NPC126998

Ingredient ID: NPC121958

Ingredient ID: NPC119250

Ingredient ID: NPC116517

Ingredient ID: NPC115448

Ingredient ID: NPC10781

Ingredient ID: NPC103560

Ingredient ID: NPC10151

Ingredient ID: NPC101079

Ingredient ID: NPC100135

Classification of Human Proteins Collectively Targeted by the Plant

Target Activity Range: ≤ 1μM
Target Type: Individual Protein of Homo sapiens
*The classification criteria of Drug Transporter (DTP), CYP450 are referred to DrugMap. Other molecular targets in CMAUP are classified as therapeutic targets.
.

Detailed Information of Target Proteins

Target Type Protein Class Gene ID Protein Name Uniprot ID Target ChEMBL ID
Therapeutic Target Small molecule receptor (family A GPCR) ADORA2A Adenosine A2a receptor P29274 CHEMBL251
Therapeutic Target Small molecule receptor (family A GPCR) ADORA1 Adenosine A1 receptor P30542 CHEMBL226
Therapeutic Target Small molecule receptor (family A GPCR) ADORA3 Adenosine A3 receptor P0DMS8 CHEMBL256
Therapeutic Target Transient receptor potential channel TRPA1 Transient receptor potential cation channel subfamily A member 1 O75762 CHEMBL6007
Clinical Trials Summary
Overview

Clinical trials associated with plant from natural product (NP) & plant level:

Clinical trials type Number of clinical trials
NP level39
Clinical trial details
NCT ID Title Condition Form in clinical use Associated by plant or compound
NCT00736164 Selenomethionine in Treating Patients Undergoing Surgery or Internal Radiation Therapy for Stage I or Stage II Prostate Cancer prostate cancer Selenomethionine (NPC291186) NP level
NCT01932112 Adenosine Effect on Persistent Pulmonary Vein Isolation Line Evaluation (APPLE Trial) atrial fibrillation Adenosine (NPC156461) NP level
NCT01690884 Effect of Ticagrelor vs. Dipyridamole on Adenosine Uptake coronary artery disease Adenosine (NPC156461) NP level
NCT00736645 Selenomethionine and Finasteride Before Surgery or Radiation Therapy in Treating Patients With Stage I or Stage II Prostate Cancer prostate cancer Selenomethionine (NPC291186) NP level
NCT00455416 Dietary Intervention in Follicular Lymphoma follicular lymphoma Selenomethionine (NPC291186) NP level
NCT00565188 Application of ATP Infusions in Palliative Home Care cancer Adenosine (NPC156461) NP level
NCT05363631 Seleno-L Methionine (SLM)-Axitinib-Pembrolizumab clear cell renal carcinoma Selenomethionine (NPC291186) NP level
NCT00030901 S9917, Selenium in Preventing Cancer in Patients With Neoplasia of the Prostate prostate cancer Selenomethionine (NPC291186) NP level
NCT00284323 Salvage: Postconditioning With Adenosine for STEMI ST Elevation Myocardial Infarction Adenosine (NPC156461) NP level
NCT02681913 Adenosine as an Adjunct to Blood Cardioplegia cardiomyopathy Adenosine (NPC156461) NP level
NCT05014061 Adenosine's Effect on STunning Resolution in Acute Myocardial Infarction Myocardial Ischemia Adenosine (NPC156461) NP level
NCT00612521 Prophylactic Intra-coronary Adenosine to Prevent Post Coronary Artery Stenting Myonecrosis coronary stenosis Adenosine (NPC156461) NP level
NCT02302768 Effect of Semet (80 and 160 mcg) Versus Placebo in Euthyroid Patients With AIT Hashimoto's thyroiditis Selenomethionine (NPC291186) NP level
NCT01593644 Phase II Study for the Diagnosis and Functional Assessment of CAD Using Transthoracic-Echodoppler coronary artery disease Adenosine (NPC156461) NP level
NCT01233492 Boron Phenylalanine With or Without Mannitol in Treating Patients With Glioblastoma Multiforme Central Nervous System Neoplasm L-Phenylalanine (NPC10781) NP level
NCT01497431 Se-Methyl-Seleno-L-Cysteine or Selenomethionine in Preventing Prostate Cancer in Healthy Participants prostate carcinoma (2R)-2-Amino-3-Methylselanylpropanoic Acid (NPC53449) NP level
NCT02535533 SLM + Axitinib for Clear Cell RCC clear cell renal carcinoma Selenomethionine (NPC291186) NP level
NCT00298636 Dose-Response of Adenosine for Perioperative Pain pain Adenosine (NPC156461) NP level
NCT01211561 Colon Cancer Prevention Using Selenium colorectal adenocarcinoma Selenomethionine (NPC291186) NP level
NCT01747174 REperfusion Facilitated by LOcal Adjunctive Therapy in ST-elevation Myocardial Infarction ST Elevation Myocardial Infarction Adenosine (NPC156461) NP level
NCT00526890 Carboplatin, Paclitaxel, Selenomethionine, and Radiation Therapy in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed by Surgery lung cancer Selenomethionine (NPC291186) NP level
NCT02867878 Adenosin to Rapidly Reverse Left Ventricle Impairment in Takotsubo Syndrome Takotsubo cardiomyopathy Adenosine (NPC156461) NP level
NCT04952129 Optimal Selenium for Bowel Polyps (OSCAR) colorectal adenoma Selenomethionine (NPC291186);(2R)-2-Amino-3-Methylselanylpropanoic Acid (NPC53449) NP level
NCT00751491 Clopidogrel Versus Adenosin in Non Urgent Percutaneous Coronary Intervention (PCI) angina pectoris Adenosine (NPC156461) NP level
NCT00625183 Capecitabine, Oxaliplatin, Selenomethionine, and Radiation Therapy in Treating Patients Undergoing Surgery For Newly Diagnosed Stage II or III Rectal Adenocarcinoma colorectal carcinoma Selenomethionine (NPC291186) NP level
NCT01123525 Adenosine Cardioplegia angina pectoris Adenosine (NPC156461) NP level
NCT00829205 Se-Methyl-Seleno-L-Cysteine, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Diffuse Large B-Cell Lymphoma That Has Relapsed or Not Responded to Treatment lymphoma (2R)-2-Amino-3-Methylselanylpropanoic Acid (NPC53449) NP level
NCT04588441 The ARCTIC Trial: Aerosolized Inhaled Adenosine Treatment in Patients With Acute Respiratory Distress Syndrome (ARDS) Caused by COVID-19 acute respiratory distress syndrome Adenosine (NPC156461) NP level
NCT04392362 A Trial to Compare American Heart Association (AHA) and Simple (SIM)Method to Give Adenosine to Treat Supra-ventricular Tachycardia (SVT) ventricular tachycardia Adenosine (NPC156461) NP level
NCT04666454 BROKEN-SWEDEHEART-Optimized Pharmacological Treatment for Broken Heart (Takotsubo) Syndrome Takotsubo cardiomyopathy Adenosine (NPC156461) NP level
NCT03236311 A Dose Titration Study to Assess the Effects of SAR407899 in Patients With MVA and/or Persistent Stable Angina Despite Angiographically Successful PCI coronary artery disease Adenosine (NPC156461) NP level
NCT00845689 Prevention of Liver Damage During Liver Surgery neoplasm Adenosine (NPC156461) NP level
NCT03032965 Adenosine to Assess Complete Conduction Block During Catheter Ablation of Paroxysmal Atrial Fibrillation atrial fibrillation Adenosine (NPC156461) NP level
NCT00179010 AMP as a Better Delivery System of Adenosine ischemia Adenosine (NPC156461) NP level
NCT00590070 THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myocardial Infarction myocardial infarction Adenosine (NPC156461) NP level
NCT00349921 Clonidine Versus Adenosine to Treat Neuropathic Pain pain Adenosine (NPC156461) NP level
NCT00580905 Role of Adenosine in the Release of VEGF and Cytokines inflammation Adenosine (NPC156461) NP level
NCT00714103 8-Chloro-Adenosine in Chronic Lymphocytic Leukemia chronic lymphocytic leukemia Adenosine (NPC156461) NP level
NCT00781404 Myocardial Protection With Adenosine During Primary Percutaneous Coronary Intervention in Pts With STEMI acute myocardial infarction Adenosine (NPC156461) NP level

❱❱❱ Associated Human Diseases and Detailed Association Evidence

 How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
 ❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.

Associated Disease of the Plant
Association Type & Detailed Evidence
Prostate cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C82
 ADORA2A
 NCT00736645,NCT00030901,NCT00736164
Other specified malignant neoplasms of kidney, except renal pelvis
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C90.Y
 ADORA3,TRPA1,ADORA3,TRPA1
Heart failure
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD10-BD1Z
 ADORA1,ADORA3,ADORA2A
Colorectal cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2B91
 ADORA2A
 NCT00625183,NCT04952129
coronary artery disease
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA8Y-BA8Z
 NCT03236311,NCT01690884,NCT01593644
Leishmaniasis
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1F54
 ADORA3,TRPA1,ADORA2A
Adenocarcinoma of pancreas
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C10.0
 ADORA3,TRPA1,ADORA2A
Malignant neoplasms of thymus
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C27
 ADORA3,TRPA1,ADORA2A
Hyper-lipoproteinaemia
Disease Category: 05.Endocrine, nutritional or metabolic diseases
Disease ICD-11 Code: 5C80
 ADORA2A,ADORA1
Glaucoma
Disease Category: 09.Diseases of the visual system
Disease ICD-11 Code: 9C61
 ADORA1,ADORA2A
Parkinsonism
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8A00
 ADORA1,ADORA2A
Solid tumour/cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A00-2F9Z
 ADORA3,ADORA2A
Lung cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C25
 ADORA2A
 NCT00526890
Orthostatic hypotension
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA21
 ADORA1,ADORA2A
Acute ST elevation myocardial infarction
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA41.0
 NCT01747174,NCT00284323
Clear cell renal cell carcinoma, NOS
Disease Category: X.Extension Codes
Disease ICD-11 Code: XH46F1
 NCT02535533,NCT05363631
Angina pectoris
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA40
 NCT00751491,NCT01123525
Atrial fibrillation
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC81.3
 NCT01932112,NCT03032965
Pain, unspecified
Disease Category: 21.Symptoms, signs or clinical findings, not elsewhere classified
Disease ICD-11 Code: MG3Z
 NCT00298636,NCT00349921
Stress-induced cardiomyopathy
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC43.5
 NCT04666454,NCT02867878
Carcinosarcoma of uterus
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C76.43
 ADORA1,TRPA1
Serous cystadenoma,borderline malignancy of ovary
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C73.4
 ADORA1,ADORA3
Pheochromocytoma
Disease Category: X.Extension Codes
Disease ICD-11 Code: XH3854
 ADORA1,ADORA2A
Malignant neoplasms of biliary tract, distal bile duct
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C15
 ADORA1,TRPA1
Diffuse large B-cell lymphomas
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A81
 ADORA1,TRPA1
Mesothelioma of pleura
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C26.0
 ADORA3,TRPA1
Melanoma of skin
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C30
 ADORA3,ADORA2A
Hepatocellular carcinoma of liver
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C12.02
 ADORA1,ADORA1
Invasive carcinoma of breast
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C61
 TRPA1,ADORA2A
Germ cell tumour of testis
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C80.2
 TRPA1,ADORA2A
Carpal tunnel syndrome
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8C10.0
 ADORA3,TRPA1
Schizophrenia
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6A20
 ADORA2A
Diabetic foot ulcer
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD54
 ADORA2A
Chronic obstructive pulmonary disease
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA22
 ADORA2A
Choreiform disorder
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8A01
 ADORA2A
Rheumatoid arthritis
Disease Category: 15.Diseases of the musculoskeletal system or connective tissue
Disease ICD-11 Code: FA20
 ADORA3
Coronary atherosclerosis
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA80
 ADORA2A
Neuropathy
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8C0Z
 TRPA1
Cardiac arrhythmia
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC9Z
 ADORA1
Radionuclide imaging
Disease Category: NA
Disease ICD-11 Code: N.A.
 ADORA2A
Pulmonary hypertension
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BB01
 ADORA2A
Mild neurocognitive disorder
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6D71
 ADORA1
Psoriasis
Disease Category: 14.Diseases of the skin
Disease ICD-11 Code: EA90
 ADORA3
Supraventricular tachyarrhythmia
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC81
 ADORA1
Chronic arterial occlusive disease
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BD4Z
 ADORA2A
Upper respiratory tract disorder
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA0Z
 TRPA1
Hepatitis virus infection
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1E50-1E51
 ADORA3
Vasomotor/allergic rhinitis
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA08
 ADORA2A
Malaria
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1F40-1F45
 ADORA3
Liver cancer
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C12
 ADORA3
Unspecific substance use disorder
Disease Category: 06.Mental, behavioural or neurodevelopmental disorders
Disease ICD-11 Code: 6C4Z
 ADORA2A
Neoplasms
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 02
 NCT00845689
Acute myocardial infarction
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA41
 NCT00781404
Mature T-cell lymphoma
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A90
 NCT00829205
Ischaemic heart diseases, unspecified
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA6Z
 NCT05014061
Acute respiratory distress syndrome
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CB00
 NCT04588441
Other specified malignant neoplasms of colon
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2B90.Y
 NCT01211561
Malignant neoplasms of prostate, unspecified
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C82.Z
 NCT01497431
Cardiomyopathy
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC43
 NCT02681913
Diseases of coronary artery, unspecified
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA8Z
 NCT00612521
Ischemia
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8B10-8B11
 NCT00179010
Ventricular tachycardia
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BC71.0
 NCT04392362
Chronic lymphocytic leukaemia or small lymphocytic lymphoma
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A82.0
 NCT00714103
Central nervous system disease
Disease Category: 08.Diseases of the nervous system
Disease ICD-11 Code: 8A04-8D87
 NCT01233492
Myocardial infarction
Disease Category: 11.Diseases of the circulatory system
Disease ICD-11 Code: BA41-BA43
 NCT00590070
Unspecified malignant neoplasms of unspecified sites
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2D4Z
 NCT00565188
NA
Disease Category: NA
Disease ICD-11 Code: NA
 NCT00580905
Hashimoto thyroiditis
Disease Category: 05.Endocrine, nutritional or metabolic diseases
Disease ICD-11 Code: 5A03.20
 NCT02302768
Follicular lymphoma
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A80
 NCT00455416
Zika virus disease
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D48
 ADORA2A
Osteoarthritis, unspecified
Disease Category: 15.Diseases of the musculoskeletal system or connective tissue
Disease ICD-11 Code: FA0Z
 TRPA1
Malignant neoplasm metastasis in lymph nodes of head, face or neck
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2D60.0
 TRPA1
Intrauterine growth restriction
Disease Category: 19.Certain conditions originating in the perinatal period
Disease ICD-11 Code: KA20.1
 ADORA2A
Squamous cell carcinoma of bronchus or lung
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C25.2
 TRPA1
West Nile virus infection
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D46
 ADORA2A
Pre-eclampsia
Disease Category: 18.Pregnancy, childbirth or the puerperium
Disease ICD-11 Code: JA24
 ADORA2A
Pneumonia due to Pseudomonasaeruginosa
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA40.05
 TRPA1
Cytomegaloviral disease
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D82
 ADORA2A
Chronic rhinosinusitis
Disease Category: 12.Diseases of the respiratory system
Disease ICD-11 Code: CA0A
 ADORA3
Malignant neoplasms of thyroid gland, unspecified
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2D10.Z
 ADORA1
Adenocarcinoma of bronchus or lung
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2C25.0
 TRPA1
Chikungunya virus disease
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1D40
 ADORA2A
Human immunodeficiency virus disease without mention of tuberculosis or malaria
Disease Category: 01.Certain infectious or parasitic diseases
Disease ICD-11 Code: 1C62
 ADORA3
Glioblastoma of brain
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A00.00
 ADORA3
Malignant neoplasms of adrenal gland
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2D11
 ADORA1
Gliomas of brain
Disease Category: 02.Neoplasms
Disease ICD-11 Code: 2A00.0
 ADORA3

❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations

Plant-Targeted Human Disease Network 
Data Section
Select to Download
1. General Info & Plant Usage & Geographical Distribution  
2. Plant Ingredients  
3. Collective Molecular Proteins  
4. Collective Enriched Activities  
5. Plant molecular targets overlapping with DEGs  
6. Associated clinical trials  
7. Associated Human Diseases  
>> Targets derived from weak experimental activities
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The CMAUP database is developed by the Bioinformatics & Drug Design group (BIDD) and School of Pharmacy, Fudan University.

CMAUP

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Principle Investigator:
Prof. Chen Yu Zong
chenyuzong@sz.tsinghua.edu.cn
Prof. Zeng Xian
zengxian@fudan.edu.cn

Developer & Maintainer:
Ph.D. Student Dongyue Hou
dyhou22@m.fudan.edu.cn
Mr. Hanbo Lin
hblin19@fudan.edu.cn
Ms. Yuhan Feng
yhfeng22@m.fudan.edu.cn

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