Collective Molecular Activities of the Plant: Alpinia Formosana
Unknown.
Japan; Taiwan
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
93 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
65 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
11 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC91411
Ingredient ID: NPC87590
Ingredient ID: NPC86906
Ingredient ID: NPC82989
Ingredient ID: NPC82329
Ingredient ID: NPC80436
Ingredient ID: NPC74856
Ingredient ID: NPC7214
Ingredient ID: NPC69144
Ingredient ID: NPC67816
Ingredient ID: NPC64246
Ingredient ID: NPC60657
Ingredient ID: NPC60372
Ingredient ID: NPC58208
Ingredient ID: NPC49653
Ingredient ID: NPC49070
Ingredient ID: NPC48660
Ingredient ID: NPC46915
Ingredient ID: NPC45267
Ingredient ID: NPC4230
Ingredient ID: NPC40174
Ingredient ID: NPC36266
Ingredient ID: NPC354
Ingredient ID: NPC34884
Ingredient ID: NPC32905
Ingredient ID: NPC306581
Ingredient ID: NPC306286
Ingredient ID: NPC305201
Ingredient ID: NPC300241
Ingredient ID: NPC293776
Ingredient ID: NPC284838
Ingredient ID: NPC283277
Ingredient ID: NPC280090
Ingredient ID: NPC279514
Ingredient ID: NPC271648
Ingredient ID: NPC262372
Ingredient ID: NPC26181
Ingredient ID: NPC26176
Ingredient ID: NPC258693
Ingredient ID: NPC248058
Ingredient ID: NPC24733
Ingredient ID: NPC244582
Ingredient ID: NPC243935
Ingredient ID: NPC239126
Ingredient ID: NPC233256
Ingredient ID: NPC229215
Ingredient ID: NPC22771
Ingredient ID: NPC226850
Ingredient ID: NPC220949
Ingredient ID: NPC219768
Ingredient ID: NPC217788
Ingredient ID: NPC21773
Ingredient ID: NPC217129
Ingredient ID: NPC216693
Ingredient ID: NPC213631
Ingredient ID: NPC208580
Ingredient ID: NPC200794
Ingredient ID: NPC197292
Ingredient ID: NPC196134
Ingredient ID: NPC195456
Ingredient ID: NPC18509
Ingredient ID: NPC182962
Ingredient ID: NPC178831
Ingredient ID: NPC169375
Ingredient ID: NPC168551
Ingredient ID: NPC163329
Ingredient ID: NPC158755
Ingredient ID: NPC158162
Ingredient ID: NPC158032
Ingredient ID: NPC154397
Ingredient ID: NPC152829
Ingredient ID: NPC152039
Ingredient ID: NPC149281
Ingredient ID: NPC148164
Ingredient ID: NPC145773
Ingredient ID: NPC14522
Ingredient ID: NPC140419
Ingredient ID: NPC134847
Ingredient ID: NPC127780
Ingredient ID: NPC12578
Ingredient ID: NPC121855
Ingredient ID: NPC120458
Ingredient ID: NPC118329
Ingredient ID: NPC116350
Ingredient ID: NPC116123
Ingredient ID: NPC115311
Ingredient ID: NPC113405
Ingredient ID: NPC109268
Ingredient ID: NPC105504
Ingredient ID: NPC1041
Ingredient ID: NPC103593
Ingredient ID: NPC102622
Ingredient ID: NPC101042
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Therapeutic Target | Methyl-lysine/arginine binding protein | SMN1 | Survival motor neuron protein | Q16637 | CHEMBL1293232 |
| Therapeutic Target | Nuclear hormone receptor subfamily 3 | NR3C1 | Glucocorticoid receptor | P04150 | CHEMBL2034 |
| Therapeutic Target | Secreted protein | SERPINA6 | Corticosteroid binding globulin | P08185 | CHEMBL2421 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2C | Alpha-2c adrenergic receptor | P18825 | CHEMBL1916 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | HRH3 | Histamine H3 receptor | Q9Y5N1 | CHEMBL264 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | ADRA2A | Alpha-2a adrenergic receptor | P08913 | CHEMBL1867 |
| Therapeutic Target | Transcription factor | HIF1A | Hypoxia-inducible factor 1 alpha | Q16665 | CHEMBL4261 |
| Therapeutic Target | Transcription factor | NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEMBL3251 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 154 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT03007147 | Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia | T-cell acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00002744 | Combination Chemotherapy in Treating Children With Newly Diagnosed Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00729794 | Vasopressin, Epinephrine, and Steroids for Cardiac Arrest | cardiac arrest | Hydrocortisone (NPC18509) | NP level |
| NCT02303821 | Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00392834 | Rituximab and Combination Chemotherapy in Treating Patients With Newly Diagnosed, HIV-Associated Burkitt's Lymphoma | lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT01860664 | Hydrocortisone Ophthalmic Ointment 0.5% for Treatment of Allergic Conjunctivitis | allergic conjunctivitis | Hydrocortisone (NPC18509) | NP level |
| NCT00002700 | Chemotherapy With or Without Bone Marrow Transplantation in Treating Patients With Acute Lymphoblastic Leukemia | leukemia;lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT00002471 | Combination Chemotherapy in Treating Patients With Acute B-Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma | leukemia;lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT01941589 | Corticosteroids+5-aminosalicylic Acid Compared to Corticosteroids in the Treatment of Moderate-severe Ulcerative Colitis | ulcerative colitis | Hydrocortisone (NPC18509) | NP level |
| NCT03817320 | PO Ixazomib in Combination With Chemotherapy for Childhood Relapsed or Refractory Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma | acute lymphoblastic leukemia;lymphoblastic lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT02790788 | Physiologic Effects of Steroids in Cardiac Arrest | cardiac arrest | Hydrocortisone (NPC18509) | NP level |
| NCT00001521 | Three Drug Combination Therapy Versus Conventional Treatment of Children With Congenital Adrenal Hyperplasia | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT00732277 | Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis - a Randomised Pilot Study | Sepsis | Hydrocortisone (NPC18509) | NP level |
| NCT02535806 | Four Drug Reinduction With Bortezomib for Relapsed or Refractory ALL or LL in Children and Young Adults | acute lymphoblastic leukemia;lymphoblastic lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT03936517 | Safety and Efficacy of Prednisolone in Adrenal Insufficiency Disease (PRED-AID Study) | adrenocortical insufficiency | Hydrocortisone (NPC18509) | NP level |
| NCT03071276 | Selinexor in Combination With Fludarabine and Cytarabine in Patients With Refractory or Relapsed Acute Myeloid Leukemia | acute myeloid leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT01451515 | NHL16: Study For Newly Diagnosed Patients With Acute Lymphoblastic Lymphoma | lymphoblastic lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT00006455 | Combination Chemotherapy in Treating Children With Anaplastic Large Cell Lymphoma (ALCL 99) | lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT00181597 | Trilostane for Androgen-Independent Prostate Cancer | prostate adenocarcinoma | Hydrocortisone (NPC18509) | NP level |
| NCT00676585 | Corticosteroid Therapy in Refractory Shock Following Cardiac Arrest | cardiac arrest | Hydrocortisone (NPC18509) | NP level |
| NCT00625209 | Activated Protein C and Corticosteroids for Human Septic Shock | septic shock | Hydrocortisone (NPC18509) | NP level |
| NCT03020030 | Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Children and Adolescents | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT02101853 | Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic Leukemia | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT05222152 | Chronocort Versus Plenadren Replacement Therapy in Adults With Adrenal Insufficiency | primary adrenal insufficiency | Hydrocortisone (NPC18509) | NP level |
| NCT03548246 | Androgen Reduction in Congenital Adrenal Hyperplasia | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT02473263 | Samu Save Sepsis: Early Goal Directed Therapy in Pre Hospital Care of Patients With Severe Sepsis and/or Septic Shock | Sepsis | Hydrocortisone (NPC18509) | NP level |
| NCT01070225 | Reversal of Acute β-Blocker Induced Bronchoconstriction | asthma | Hydrocortisone (NPC18509) | NP level |
| NCT00375713 | Randomized Phase III Study to Evaluate the Efficacy and Safety of Xyzal® (Levocetirizine) vs Zyrtec® (Cetirizine) in Subjects With Dermatitis and Eczema | dermatitis;Eczema | Hydrocortisone (NPC18509) | NP level |
| NCT04231708 | Effects of Pharmacological Stress and rTMS on Executive Function in Opioid Use Disorder | opioid use disorder | Hydrocortisone (NPC18509) | NP level |
| NCT01867294 | Spironolactone in Preventing Rash in Patients With Advanced Cancer Receiving Panitumumab and Cetuximab | cancer | Hydrocortisone (NPC18509) | NP level |
| NCT03062280 | A Study of the Efficacy, Safety and Tolerability of Chronocort in Treating CAH | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT00915343 | Once-daily Oral Modified Release Hydrocortisone in Patients With Adrenal Insufficiency | adrenocortical insufficiency | Hydrocortisone (NPC18509) | NP level |
| NCT00358748 | Early Use of Hydrocortisone in Hypotensive Very Low Birth Weight Infants | hypotension | Hydrocortisone (NPC18509) | NP level |
| NCT04348305 | Hydrocortisone for COVID-19 and Severe Hypoxia | COVID-19;hypoxia | Hydrocortisone (NPC18509) | NP level |
| NCT00002785 | Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT02270788 | Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies | acute myeloid leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00005802 | Chemotherapy Followed by Donor White Blood Cells Plus Interleukin-2 in Treating Patients With Acute Myeloid or Lymphocytic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00165178 | Treatment of Acute Lymphoblastic Leukemia in Children | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00980876 | A Comparative Study Between Two Formulations of the Ciprofloxacin Hydrochloride + Hydrocortisone Otic Suspension | otitis externa | Hydrocortisone (NPC18509) | NP level |
| NCT00098839 | Chemoimmunotherapy With Epratuzumab in Relapsed Acute Lymphoblastic Leukemia (ALL) | childhood acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT05160506 | Corticosteroids to Treat Pancreatitis | pancreatitis | Hydrocortisone (NPC18509) | NP level |
| NCT00002855 | Chemotherapy Plus Hormone Therapy Versus Androgen Suppression in Treating Patients With Metastatic or Unresectable Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT00002921 | S9427, Suramin in Treating Patients With Stage III or Stage IV Adrenocortical Cancer Incurable by Surgery | adrenal cortex carcinoma | Hydrocortisone (NPC18509) | NP level |
| NCT04921189 | Steroid, Thiamine and Ascorbic Acid for Comatose Out-of-hospital Cardiac Arrest Survivors | cardiac arrest | Hydrocortisone (NPC18509) | NP level |
| NCT05063994 | Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT03670212 | Investigation of Nicotine Seeking Behavior in Current Smokers | nicotine dependence | Hydrocortisone (NPC18509) | NP level |
| NCT03333278 | The Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock Trial | Sepsis;septic shock | Hydrocortisone (NPC18509) | NP level |
| NCT00590018 | Corticosteroids in Postoperative Critically Ill Neonates With Low Cardiac Output Syndrome With Congenital Heart Disease | heart failure | Hydrocortisone (NPC18509) | NP level |
| NCT00003728 | Combination Chemotherapy Plus Steroid Therapy in Treating Children With Acute Lymphoblastic Leukemia or Lymphoblastic Non-Hodgkin's Lymphoma | leukemia;lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT00895310 | Use of Low Dose Ketoconazole in Prostate Cancer That Does Not Respond to Hormone Therapy and Prior Chemotherapy | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT03261336 | Oral Calcitriol With Ketoconazole in CRPC | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT02196142 | Acute Effects of Cortisol on Alcohol Craving in Alcohol Dependence | alcohol dependence | Hydrocortisone (NPC18509) | NP level |
| NCT00460031 | Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT00309894 | Ketoconazole, Hydrocortisone, and GM-CSF in Treating Patients With Progressive Prostate Cancer After Hormone Therapy | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT00354107 | Ifosfamide, Carboplatin, Etoposide, and SGN-30 in Treating Young Patients With Recurrent Anaplastic Large Cell Lymphoma | anaplastic large cell lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT02425852 | A Randomized, Multicenter Open Label Study Comparing Early Administration of Azathioprine Plus IFX to Steroids Plus Azathioprine for Acute Severe Colitis | ulcerative colitis | Hydrocortisone (NPC18509) | NP level |
| NCT00003215 | Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Newly Diagnosed Aggressive Non-Hodgkin's Lymphoma | lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT01064986 | The Effects of Hydrocortisone in Endotoxemia in Normal Volunteers | infection | Hydrocortisone (NPC18509) | NP level |
| NCT00003436 | Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myeloid Leukemia | leukemia;myelodysplastic syndrome | Hydrocortisone (NPC18509) | NP level |
| NCT00002704 | Radiation Therapy and Chemotherapy in Treating Children With CNS Relapse From Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT01718964 | Acute Effects of Cortisol on Heroin Craving in Opioid Dependence (Ghost-Basel) | opioid dependence | Hydrocortisone (NPC18509) | NP level |
| NCT00220454 | Effect of Estrogen & Stress for Postmenopausal Women | aging | Hydrocortisone (NPC18509) | NP level |
| NCT05276323 | Medihoney® Derma Cream Treatment for Mild to Moderate Atopic Dermatitis in Children Study | atopic eczema | Hydrocortisone (NPC18509) | NP level |
| NCT02256865 | Hormonal Mechanisms of Sleep Restriction | insulin resistance | Hydrocortisone (NPC18509) | NP level |
| NCT05139849 | VAsopressin and STeroids in Addition to Adrenaline in Cardiac Arrest - a Randomized Clinical Trial | cardiac arrest | Hydrocortisone (NPC18509) | NP level |
| NCT01399268 | Steroids in Bilateral Total Knee Replacement | inflammation | Hydrocortisone (NPC18509) | NP level |
| NCT00899847 | Phase 2 Study of Autologous Followed by Nonmyeloablative Allogeneic Transplantation Using TLI & ATG | multiple myeloma | Hydrocortisone (NPC18509) | NP level |
| NCT03209102 | Emotional Regulation and Impulsivity Among Adolescents With Borderline Personality Disorder | Borderline personality disorder | Hydrocortisone (NPC18509) | NP level |
| NCT00953576 | Ketoconazole, Hydrocortisone, Dutasteride and Lapatinib (KHAD-L) in Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT00673127 | Ketoconazole, Hydrocortisone and Dutasteride in Asymptomatic Hormone Refractory Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT02735707 | Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia | COVID-19;influenza;pneumonia | Hydrocortisone (NPC18509) | NP level |
| NCT00705822 | Combination of Docetaxel + Estramustine + Hydrocortisone Versus Docetaxel + Prednisone in Patients With Advanced Prostate Cancer | prostate adenocarcinoma | Hydrocortisone (NPC18509) | NP level |
| NCT01453686 | A Trial of Clobetasol Propionate Versus Hydrocortisone in Children With Alopecia Areata | alopecia areata | Hydrocortisone (NPC18509) | NP level |
| NCT00136435 | A Study in Adults With Untreated Acute Lymphoblastic Leukemia | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT01574612 | Open Label Safety Study of Xerese Cream in the Treatment of Recurrent Herpes Labialis in Children 6-11 Years Old | Herpes Labialis | Hydrocortisone (NPC18509) | NP level |
| NCT03509350 | Vitamin C, Thiamine, and Steroids in Sepsis | Sepsis | Hydrocortisone (NPC18509) | NP level |
| NCT02465606 | A Study to Evaluate the Safety of Lebrikizumab Compared to Topical Corticosteroids in Adult Patients With Atopic Dermatitis | atopic eczema | Hydrocortisone (NPC18509) | NP level |
| NCT03682393 | Post-operative Corticosteroid Treatment After Mitral Valve Surgery | atrial fibrillation | Hydrocortisone (NPC18509) | NP level |
| NCT01574014 | Glucocorticoid Treatment for Social Phobia | phobic disorder | Hydrocortisone (NPC18509) | NP level |
| NCT00482053 | Phase 2 Poor Risk DLBCL of TLI and ATG Followed by Matched Allogeneic HT as Consolidation to Autologous HCT | diffuse large B-cell lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT00176462 | CINJALL: Treatment for Children With Acute Lymphocytic Leukemia | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT03349281 | Pevonedistat With VXLD Chemotherapy for Adolescent/Young Adults With Relapsed/Refractory ALL or Lymphoblastic NHL | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00519818 | Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia | classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency | Hydrocortisone (NPC18509) | NP level |
| NCT00002494 | Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia | leukemia;lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT01104025 | Hybrid Immunotherapy for Hemophagocytic LymphoHistiocytosis | hemophagocytic syndrome | Hydrocortisone (NPC18509) | NP level |
| NCT03592693 | Vitamin C, Hydrocortisone and Thiamine for Septic Shock | septic shock | Hydrocortisone (NPC18509) | NP level |
| NCT00002757 | TITLE:Less Intensive Therapy for Children With Non-Hodgkin's Lymphoma | leukemia;lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT01847690 | Effect of Cortisol on Physical Exertion in Patients With Primary Adrenal Failure | chronic primary adrenal insufficiency | Hydrocortisone (NPC18509) | NP level |
| NCT01007591 | A Study Comparing LEO 80190 Ointment With Hydrocortisone Ointment, Both Applied Once Daily in the Treatment of Psoriasis Vulgaris on the Face and Intertriginous Areas | psoriasis vulgaris | Hydrocortisone (NPC18509) | NP level |
| NCT00002756 | Induction Intensification in Treating Infants With Newly Diagnosed Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00019409 | Radiation Therapy to the Head or Intrathecal Chemotherapy Plus High Dose Cytarabine in Preventing CNS Disease in Children With Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00704262 | Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin Folds | psoriasis vulgaris | Hydrocortisone (NPC18509) | NP level |
| NCT00002805 | Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00563303 | Treatment of Polytraumatisms With Corticoids | injury | Hydrocortisone (NPC18509) | NP level |
| NCT00536991 | Calcitriol in Combination With Ketoconazole and Therapeutic Hydrocortisone in Treating Patients With Prostate Cancer | prostate adenocarcinoma | Hydrocortisone (NPC18509) | NP level |
| NCT03872011 | Vitamin C, Thiamine and Hydrocortisone for the Treatment of Septic Shock | septic shock | Hydrocortisone (NPC18509) | NP level |
| NCT00004034 | Treatment of Childhood Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00002881 | Flutamide, Suramin, and Hydrocortisone in Treating Patients With Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT01014364 | Low Doses Corticosteroids as Adjuvant Therapy for the Treatment of Severe H1N1 Flu | influenza;viral pneumonia | Hydrocortisone (NPC18509) | NP level |
| NCT03237689 | Effects of Glucocorticoids on Cognition in HIV-infected Women | HIV infection | Hydrocortisone (NPC18509) | NP level |
| NCT01735617 | Pilot Study to Characterize and Examine the Pharmacokinetics and Efficacy of Chronocort® in Adults With CAH | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT04293562 | A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations | acute myeloid leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00320099 | Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock | septic shock | Hydrocortisone (NPC18509) | NP level |
| NCT00002865 | High-Intensity, Brief-Duration Chemotherapy in Treating Patients With Relapsed or Refractory Acute Lymphocytic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT01960530 | An Investigational Study of Hydrocortisone | adrenocortical insufficiency | Hydrocortisone (NPC18509) | NP level |
| NCT00002760 | Antiandrogen Withdrawal in Treating Patients With Hormone-Refractory Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT00859781 | 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT01771328 | Continuous Subcutaneous Hydrocortisone Infusion in Congenital Adrenal Hyperplasia | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT00640822 | Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment Compared With Tacalcitol Ointment in Patients With Psoriasis on the Face and Skin Folds | psoriasis vulgaris | Hydrocortisone (NPC18509) | NP level |
| NCT03649633 | Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock | septic shock | Hydrocortisone (NPC18509) | NP level |
| NCT00002798 | Combination Chemotherapy With or Without Bone Marrow Transplantation in Treating Children With Acute Myelogenous Leukemia or Myelodysplastic Syndrome | acute erythroleukemia;acute megakaryoblastic leukaemia;acute monocytic leukemia;acute myeloblastic leukemia without maturation;acute myelomonocytic leukemia;chronic myelomonocytic leukemia;refractory anemia;refractory anemia with excess blasts | Hydrocortisone (NPC18509) | NP level |
| NCT01913158 | Safety and Efficacy Study of Anucort HC TM 25mg Rectal Suppositories to Treat Symptomatic Internal Hemorrhoids | hemorrhoid | Hydrocortisone (NPC18509) | NP level |
| NCT00400946 | Treatment of Acute Lymphoblastic Leukemia in Children | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT03371784 | The Effect of Glucocorticoid Therapy on Left Ventricular Remodelling in Acute Myocardial Infarction (RECONSIDER) | myocardial infarction | Hydrocortisone (NPC18509) | NP level |
| NCT02602210 | Supplemental Corticosteroids in Cirrhotic Hypotensive Patients With Suspicion of Sepsis | cirrhosis of liver | Hydrocortisone (NPC18509) | NP level |
| NCT03019614 | An Open Label Study in Healthy Volunteers to Compare Chronocort® to Hydrocortisone | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT03913559 | Inotuzumab Ozogamicin for Children With MRD Positive CD22+ Lymphoblastic Leukemia | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT02714543 | Evaluation of Efficacy of Aloevera in the Treatment of Oral Submucous Fibrosis- A Clinical Study | oral submucous fibrosis | Hydrocortisone (NPC18509) | NP level |
| NCT00003593 | Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome | leukemia;myelodysplastic syndrome;myeloproliferative disorder | Hydrocortisone (NPC18509) | NP level |
| NCT04359511 | Efficacy and Safety of Corticosteroids in Oxygen-dependent Patients With COVID-19 Pneumonia | COVID-19 | Hydrocortisone (NPC18509) | NP level |
| NCT00623740 | PREMILOC Trial to Prevent Bronchopulmonary Dysplasia in Very Preterm Neonates | bronchopulmonary dysplasia | Hydrocortisone (NPC18509) | NP level |
| NCT02212561 | Selinexor With Fludarabine and Cytarabine for Treatment of Refractory or Relapsed Leukemia or Myelodysplastic Syndrome | acute lymphoblastic leukemia;myelodysplastic syndrome | Hydrocortisone (NPC18509) | NP level |
| NCT00618501 | Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT04898894 | Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia | acute leukemia of ambiguous lineage | Hydrocortisone (NPC18509) | NP level |
| NCT00133991 | Combination Chemotherapy and Rituximab in Treating Patients With Newly Diagnosed Burkitt's Lymphoma or Leukemia | leukemia;lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT03710187 | HCT+F vs. HCT Alone in Critically Ill Medical Septic Shock Patients | septic shock | Hydrocortisone (NPC18509) | NP level |
| NCT00236925 | Efficacy Study of Low-Dose Hydrocortisone Treatment for Fibromyalgia | fibromyalgia | Hydrocortisone (NPC18509) | NP level |
| NCT01828515 | Vilazodone for Corticosteroid-Induced Memory Impairment | memory impairment | Hydrocortisone (NPC18509) | NP level |
| NCT00186628 | Phase 2 Trial of Prophylactic Rituximab Therapy for Prevention of CGVHD | mast-cell leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00691002 | Efficacy and Safety of Calcipotriol Plus Hydrocortisone Ointment in Psoriasis Vulgaris on the Face and Skin Folds | psoriasis vulgaris | Hydrocortisone (NPC18509) | NP level |
| NCT02517489 | Community-Acquired Pneumonia : Evaluation of Corticosteroids | pneumonia | Hydrocortisone (NPC18509) | NP level |
| NCT00006371 | A Phase II Trial of Early Medical Adrenalectomy for "D0.5" Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT01450930 | Pharmacokinetics of Hydrocortisone After Subcutaneous Administration in Chronic Adrenal Insufficiency | primary adrenal insufficiency | Hydrocortisone (NPC18509) | NP level |
| NCT01265017 | Role of Pregnancy Related Hormones in Lowering the Insulin Requirement in Pregnant Women With Type 1 Diabetes | type 1 diabetes mellitus | Hydrocortisone (NPC18509) | NP level |
| NCT00670254 | Hydrocortisone for Prevention of Septic Shock | Sepsis | Hydrocortisone (NPC18509) | NP level |
| NCT04181515 | Using rTMS to Explore Neural Mechanisms of Stress-Induced Opioid Use | opioid use disorder | Hydrocortisone (NPC18509) | NP level |
| NCT01859312 | Comparison of Cortisol Pump With Standard Treatment for Congenital Adrenal Hyperplasia | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT02096510 | Ultradian Subcutaneous Hydrocortisone Infusion in Addison Disease and Congenital Adrenal Hyperplasia | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT00002552 | Chemotherapy Plus Bone Marrow Transplantation in Treating Patients With Refractory Non-Hodgkin's Lymphoma, Hodgkin's Disease, or Multiple Myeloma | multiple myeloma | Hydrocortisone (NPC18509) | NP level |
| NCT00002816 | Combination Chemotherapy in Treating Children With Relapsed Acute Lymphoblastic Leukemia | leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00131053 | Applying Pediatric Regimens to Younger Adult Patients With Acute Lymphoblastic Leukemia (ALL) | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT01036594 | Ketoconazole and Dexamethasone in Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT00027859 | Hormone Therapy Compared With Combination Chemotherapy in Treating Patients With Prostate Cancer | prostate cancer | Hydrocortisone (NPC18509) | NP level |
| NCT00873093 | Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma | B-cell acute lymphoblastic leukemia;lymphoblastic lymphoma | Hydrocortisone (NPC18509) | NP level |
| NCT00623766 | Evaluation of Tumor Response to Ipilimumab in the Treatment of Melanoma With Brain Metastases | melanoma | Hydrocortisone (NPC18509) | NP level |
| NCT02419755 | Bortezomib and Vorinostat in Younger Patients With Refractory or Relapsed MLL Rearranged Hematologic Malignancies | acute leukemia of ambiguous lineage;acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00621985 | Dexamethasone Treatment of Congenital Adrenal Hyperplasia | congenital adrenal hyperplasia | Hydrocortisone (NPC18509) | NP level |
| NCT01063569 | Glucocorticoid Treatment in Addison's Disease | chronic primary adrenal insufficiency | Hydrocortisone (NPC18509) | NP level |
| NCT00805285 | The Use of Oral Budesonide and Rectal Hydrocortisone for the Treatment of Active Ulcerative Colitis | ulcerative colitis | Hydrocortisone (NPC18509) | NP level |
| NCT01186328 | EZN-3042 Administered With Re-induction Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL) | acute lymphoblastic leukemia | Hydrocortisone (NPC18509) | NP level |
| NCT00084838 | Chemotherapy Combined With Radiation Therapy for Newly Diagnosed CNS AT/RT | Central Nervous System Neoplasm | Hydrocortisone (NPC18509) | NP level |
| NCT00004669 | Phase II Pilot Study of Early Cortisol Replacement to Prevent Bronchopulmonary Dysplasia | bronchopulmonary dysplasia | Hydrocortisone (NPC18509) | NP level |
| NCT02722200 | Investigating the Central and Peripheral Mechanisms by Which Glucocorticoids Affect Hunger | obesity | Hydrocortisone (NPC18509) | NP level |
| NCT02043587 | Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphoma | acute lymphoblastic leukemia;lymphoblastic lymphoma | Hydrocortisone (NPC18509) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Septic shockDisease Category: X.Extension CodesDisease ICD-11 Code: XS26 |
NCT00320099,NCT03872011,NCT00625209,NCT03592693,NCT03649633,NCT03333278,NCT03710187
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
NR3C1,NR3C1,NFKB1
NCT02465606,NCT05276323,NCT00375713 |
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
NFKB1
NCT01007591,NCT00691002,NCT00640822,NCT00704262 |
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
NFKB1
NCT00002798,NCT03071276,NCT04293562,NCT02270788 |
Precursor B-lymphoblastic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A70 |
NCT02043587,NCT02535806,NCT00873093,NCT03817320,NCT01451515
|
SepsisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G40-1G41 |
NCT03509350,NCT00732277,NCT02473263,NCT00670254,NCT03333278
|
Cardiac arrestDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MC82 |
NCT02790788,NCT00676585,NCT04921189,NCT05139849,NCT00729794
|
Adrenocortical insufficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A74 |
NCT01960530,NCT05222152,NCT01450930,NCT03936517,NCT00915343
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
HRH3,ADRA2A,NR3C1,ADRA2C
|
Opioid use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C43 |
ADRA2A
NCT01718964,NCT04231708,NCT04181515 |
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
SERPINA6
NCT00536991,NCT00181597,NCT00705822 |
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
SERPINA6,HIF1A,ADRA2C,SMN1
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
HRH3,NR3C1,ADRA2A,ADRA2C
|
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
NR3C1,ADRA2C
NCT01064986 |
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
NR3C1,SERPINA6
NCT01070225 |
Vasomotor/allergic rhinitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA08 |
NR3C1,ADRA2C,HRH3
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
HIF1A,NR3C1,NFKB1
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04359511,NCT02735707,NCT04348305
|
Ulcerative colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD71 |
NCT02425852,NCT00805285,NCT01941589
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
NCT00003593,NCT02212561,NCT00003436
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
HRH3,NR3C1,ADRA2A
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
ADRA2A,HIF1A,ADRA2C
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
ADRA2A,ADRA2C,SMN1
|
LeukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2B33 |
NCT00002816,NCT00002704,NCT00133991,NCT00004034,NCT00002700,NCT00002757,NCT00003728,NCT00002471,NCT00003593,NCT00618501,NCT00002744,NCT00003436,NCT00002494,NCT00005802,NCT00002805,NCT00002865,NCT00002756,NCT00002785,NCT00019409,NCT00400946
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
ADRA2C,HRH3
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
NFKB1,NR3C1
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
NR3C1,SERPINA6
|
Otitis externaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA00-AA13 |
NR3C1
NCT00980876 |
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
HRH3,ADRA2A
|
Muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70 |
NR3C1,NFKB1
|
Muscular atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B61 |
SMN1,SMN2
|
HypotensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA20-BA21 |
ADRA2C
NCT00358748 |
ObesityDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B80-5B81 |
ADRA2C
NCT02722200 |
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
NR3C1,NFKB1
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
ADRA2C,HRH3
|
Pulmonary hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BB01 |
ADRA2C,HIF1A
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
NR3C1,ADRA2A
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
NR3C1,SERPINA6
|
Indeterminate colitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD72 |
NR3C1,NFKB1
|
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
ADRA2C,ADRA2A
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
NFKB1,NR3C1
|
PneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40 |
NCT02517489,NCT02735707
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
NCT02735707,NCT01014364
|
Acute leukaemias of ambiguous lineageDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A61 |
NCT04898894,NCT02419755
|
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
NCT00899847,NCT00002552
|
Bronchopulmonary dysplasia originating in the perinatal periodDisease Category: 19.Certain conditions originating in the perinatal periodDisease ICD-11 Code: KB29.0 |
NCT00004669,NCT00623740
|
Acquired adrenocortical insufficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A74.0 |
NCT01847690,NCT01063569
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HRH3,SERPINA6
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
ADRA2A,SMN1
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
HRH3,ADRA2C
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
NFKB1,ADRA2C
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
HRH3,SERPINA6
|
Precursor cell lymphoblastic leukaemia, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH5J37 |
NCT01186328,NCT02535806,NCT03817320,NCT00136435,NCT02101853,NCT02303821,NCT03020030,NCT00165178,NCT02043587,NCT00176462,NCT00098839,NCT03349281,NCT02212561,NCT00131053,NCT02419755,NCT03913559
|
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
NR3C1
NCT00027859,NCT00859781,NCT00006371,NCT03261336,NCT00460031,NCT00002760,NCT00953576,NCT00673127,NCT00895310,NCT01036594,NCT00309894,NCT00002881,NCT00002855 |
Congenital adrenal hyperplasiaDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A71.01 |
NCT00519818,NCT03548246,NCT02096510,NCT00621985,NCT01771328,NCT03019614,NCT00001521,NCT03062280,NCT01735617,NCT01859312,NCT05063994
|
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
HIF1A
NCT00003215,NCT00002757,NCT00392834,NCT00002700,NCT00003728,NCT00002494,NCT00006455,NCT00133991,NCT00002471 |
Adaptive immunity immunodeficiencyDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01 |
NR3C1
|
Mood disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A60-6E23 |
NR3C1
|
General pain disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E43 |
ADRA2C
|
SomnolenceDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG42 |
HRH3
|
Adrenomedullary hyperfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A75 |
HIF1A
|
Post-traumatic stress disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B40 |
ADRA2C
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ADRA2C
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
NFKB1
|
Choreiform disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01 |
NFKB1
|
Spine/trunk injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND51 |
NR3C1
|
Acute/subacute hepatic failureDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB91 |
NFKB1
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
HRH3
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
NR3C1
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
HRH3
|
Dissociative neurological symptom disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B60 |
ADRA2C
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
NR3C1
|
NarcolepsyDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A20 |
HRH3
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
HRH3
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
NR3C1
|
Adrenogenital disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A71 |
NR3C1
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
ADRA2C
|
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
HRH3
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
ADRA2C
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
NR3C1
|
Allergic/hypersensitivity disorderDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A80-4A8Z |
NR3C1
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
NFKB1
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
NFKB1
|
Respiratory system diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB40-CB7Z |
SERPINA6
|
Skin and skin-structure infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F28-1G0Z |
NFKB1
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
NFKB1
|
Vitamin deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B55-5B5F |
NR3C1
|
Sleep-wake disorderDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7B2Z |
HRH3
|
Non-specific cutaneous vascular symptonDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: ME64 |
ADRA2C
|
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
HIF1A
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NR3C1
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT01867294
|
Allergic conjunctivitisDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A60.02 |
NCT01860664
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
NCT00482053
|
Anaplastic large cell lymphoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH1LC0 |
NCT00354107
|
Burkitt-like lymphoma with 11q aberrationDisease Category: X.Extension CodesDisease ICD-11 Code: XH8NN2 |
NCT00873093
|
Personality disorder, severity unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D10.Z |
NCT03209102
|
Primary haemophagocytic lymphohistiocytosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01.23 |
NCT01104025
|
Acute myelomonocytic leukaemiaDisease Category: X.Extension CodesDisease ICD-11 Code: XH78Y4 |
NCT00002798
|
Oral submucous fibrosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA02.2 |
NCT02714543
|
Adult T-cell lymphoma or leukaemia, human T-cell lymphotropic virus type 1-associatedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90.5 |
NCT03007147
|
Viral pneumoniaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.1 |
NCT01014364
|
PancreatitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC31-DC34 |
NCT05160506
|
Alopecia areataDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED70.2 |
NCT01453686
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
NCT00002798
|
Acute monocytic leukaemiaDisease Category: X.Extension CodesDisease ICD-11 Code: XH9NE2 |
NCT00002798
|
Alcohol dependenceDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40.2 |
NCT02196142
|
NADisease Category: NADisease ICD-11 Code: NA |
NCT01399268
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
NCT03371784
|
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
NCT00623766
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT03237689
|
Nicotine use disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C4A |
NCT03670212
|
Adrenal cortical carcinomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH4KH2 |
NCT00002921
|
Acute megakaryoblastic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60.36 |
NCT00002798
|
Type1diabetesmellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10 |
NCT01265017
|
Refractory anaemia with excess of blastsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A35 |
NCT00002798
|
Acute erythroid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60.35 |
NCT00002798
|
Mast cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21.00 |
NCT00186628
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT02602210
|
Dermatitis or eczema, unspecifiedDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA8Z |
NCT00375713
|
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
NCT00003593
|
Central nervous system diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A04-8D87 |
NCT00084838
|
HaemorrhoidsDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB60 |
NCT01913158
|
Herpes simplex labialisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00.01 |
NCT01574612
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
NCT00590018
|
Anxiety or fear-related disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6B0Z |
NCT01574014
|
Age-associated cognitive declineDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MB21.0 |
NCT01828515
|
Insulin-resistance syndromesDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A44 |
NCT02256865
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
NCT03682393
|
AsphyxiaDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MD11.1 |
NCT04348305
|
Refractory anaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A30 |
NCT00002798
|
Chronic widespread painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30.01 |
NCT00236925
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
NCT00563303
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT00220454
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
ADRA2C
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
ADRA2C
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
SERPINA6
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
ADRA2A
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
NFKB1
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
HIF1A
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
ADRA2C
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
ADRA2A
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
SERPINA6
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
ADRA2C
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
ADRA2A
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
HRH3
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
HIF1A
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
