Plant ID: NPO11045
Plant Latin Name: Paederia Scandens
Taxonomy Genus: Paederia
Taxonomy Family: Rubiaceae
NCBI TaxonomyDB:
284589
Plant-of-the-World-Online:
n.a.
Carminative; Depurative; Vermifuge
Philippines; Indonesia; India; United States; Vietnam; China; Thailand
Ingredient ID: NPC93084
Ingredient ID: NPC88603
Ingredient ID: NPC78235
Ingredient ID: NPC68903
Ingredient ID: NPC68889
Ingredient ID: NPC64866
Ingredient ID: NPC56161
Ingredient ID: NPC55416
Ingredient ID: NPC52955
Ingredient ID: NPC49151
Ingredient ID: NPC48645
Ingredient ID: NPC46358
Ingredient ID: NPC44095
Ingredient ID: NPC41180
Ingredient ID: NPC36545
Ingredient ID: NPC31786
Ingredient ID: NPC317591
Ingredient ID: NPC313918
Ingredient ID: NPC313528
Ingredient ID: NPC306344
Ingredient ID: NPC301585
Ingredient ID: NPC291545
Ingredient ID: NPC281943
Ingredient ID: NPC279028
Ingredient ID: NPC277917
Ingredient ID: NPC271027
Ingredient ID: NPC259512
Ingredient ID: NPC252041
Ingredient ID: NPC239406
Ingredient ID: NPC235432
Ingredient ID: NPC233533
Ingredient ID: NPC23288
Ingredient ID: NPC226580
Ingredient ID: NPC21848
Ingredient ID: NPC217226
Ingredient ID: NPC216630
Ingredient ID: NPC215909
Ingredient ID: NPC214067
Ingredient ID: NPC21180
Ingredient ID: NPC196776
Ingredient ID: NPC194465
Ingredient ID: NPC194458
Ingredient ID: NPC190810
Ingredient ID: NPC180871
Ingredient ID: NPC179694
Ingredient ID: NPC176309
Ingredient ID: NPC173543
Ingredient ID: NPC167072
Ingredient ID: NPC146682
Ingredient ID: NPC144403
Ingredient ID: NPC138925
Ingredient ID: NPC13483
Ingredient ID: NPC11609
Ingredient ID: NPC112866
Ingredient ID: NPC105998
Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
---|---|---|---|---|---|
Therapeutic Target | Fatty acid binding protein family | FABP4 | Fatty acid binding protein adipocyte | P15090 | CHEMBL2083 |
Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 2 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT00885599 | Efficacy of a Naturally-derived Mouthrinse for Gingival Inflammation | gingivitis | Thymol (NPC259512) | NP level |
NCT01637948 | Controlled Clinical Trial of Traditional Chinese Medicine Mouthrinse | gingivitis | Thymol (NPC259512) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
OR51E2,LMNA,FABP5,FABP4
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
OR51E2,LMNA,FABP5
|
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
OR51E2,FABP5,FABP4
|
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
FABP5,OR51E2,FABP5
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
OR51E2,FABP5,FABP4
|
Gingival diseasesDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA0B |
NCT00885599,NCT01637948
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
OR51E2,FABP5
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
LMNA,OR51E2
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
LMNA,OR51E2
|
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
OR51E2,FABP5
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
LMNA,FABP5
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
OR51E2,FABP5
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
FABP5
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
FABP5
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
FABP5
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
FABP4
|
Non-alcoholic fatty liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB92 |
FABP4
|
Malignant neoplasms of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
FABP4
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
OR51E2
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
LMNA
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
FABP4
|
Malignant neoplasms of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
FABP4
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
LMNA
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
FABP5
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
FABP5
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
OR51E2
|
Malignant neoplasm of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
FABP4
|