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Collective Molecular Activities of the Plant: Petasites Japonicus


Example Image
PLANiTS DNA barcode

Click for details-----ITS

TCGAAAACTGCATAGCAAAACGACTCGTGAACATGTTACAACAATCTGGTGTCCTTAGTGTCGGGCTCTTGTTCGATATTTTGGATGCCTTGTCGATATGCATCTTTGGTCAGCCCATTGGGTTCTAAGGATGTCACATTGACACAACAACAATCCCCGGCACGACATGTGCCAAGGAAAATTAAACTTAAGAAGGGCCCGTACCATGCTCCCCCGTTTGTGGGGTTTTGCATGGGATGTGGCTTTTTTATAATCACAAATGACTCTCGGCAACGGATATCTCGGCTCACGCAGTCATGAAGAACGTAGCAAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTTTTTGAACGCAAGTTGCGCCCGAAGCCTTTTGGCCGAGGGCACGTCTGCCTGGGCGTCACACATCGCGTCGCCCCCACCATGCCTCCTTGATGGGGATGCTTGGATTGGGGCGGAAATTGGTCTCCCGTTCCTATGGTGCGGTTGCCTAAAATAGGAGTCCCTTCTAACGGACGCATGATTAGTGGTGGTTGACAATACCCTCTTATCAAGTTGTGTGTTCTAAGTAGTAAGGAAGATCTCTTCAATGACCCTAGGTTGTCGTCTTGTGACGATGATTCGACC

Click for details-----ITS1

NA

Click for details-----ITS2

NA
Taxonomic Information

Plant ID: NPO10980
Plant Latin Name: Petasites Japonicus
Taxonomy Genus: Petasites
Taxonomy Family: Asteraceae

Plant External Links:

NCBI TaxonomyDB: 186965
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:
South Korea; China

Traditional Medicine System:
TCM


Medicinal Functions:

Antiasthmatic; Antispasmodic; Expectorant; Miscellany; Poultice

Geographical Distribution

South Korea; China

Geographical Distribution
See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

208 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.


156 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)

38 Ingredients with experimental-derived Activity

Unique ingredients have activity data available.






Ingredient Structrual Cards


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