CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Peganum Harmala

Example Image

PLANiTS DNA barcode

Click for details-----ITS

TGAACCTGCGGAAGGATCATTGTCGAAACCTGCGCAGCAGAACGACCCGCGAACACGTCACAACTCCGGGGGGACGGCCCGCCGTTCCCCCCGCCGTGGCGCGGACGGGAGGCGTCGCGCTCGCGCGCGCCCCTCCGTCCCGCGCCTCGGACCCACGAACCCCGGCGCAACGCGCGCCAAGGAAACTCAAACGAGAGAGCCGGTCGGCCTCGCCCCGGACACGGTGCGGCGTCGGCCGTGCCTCCTTTCGATACGCAACAACGACTCTCGGCAACGGATATCTCGGCTCTCGCATCGATGAAGAACGTAGCGAAATGCGATACTTGGTGTGAATTGCAGAATCCCGTGAACCATCGAGTCTTTGAACGCAAGTTGCGCCCCAAGCCGTCAGGCCGAGGGCACGCCTGCCTGGGCGTCACGCATTGAAACCTCCTGCCAATTTCCTTTTGATAGGTATTGTGCAGGGTGGACGTTGGCCTCCCGTGAGCTCTTTTGTCTCATGGTTGGTTGAAAATTGAGACCTTGGTAGGGTGTGCCTTGATAAATGGTGGTTGTGTGACCCACGAGACCAATCATGCGCTGCTCTATTTGATTTGGCCTCCTTTACCCATATGCGTTTCTAAACGCTCGTG

Click for details-----ITS1

Click for details-----ITS2

ATCGTCGCCCCCCCGCCGCTCCCYGCGCCCCTCTCCGGGGGACGGGTCGCGSGSGGGTGGGCGGAGATTGSCCTCCCGCRAGTCMCCCCTCGYGGCTGGCCKAAATACSGATCCCCGGCCRGCGGTGGCCGCGACGTTSGGTGGTCGTAACGCGCCTCGTGAACCCGTCGCGCGCYCCGCTTCKCCTCTSGCGGGATCCCCGGCCCCGAGGCGGCGCARGCCGCTCGCA

Taxonomic Information

Plant ID: NPO1085
Plant Latin Name: Peganum Harmala
Taxonomy Genus: Peganum
Taxonomy Family: Nitrariaceae

Plant External Links:

NCBI TaxonomyDB: 43879
Plant-of-the-World-Online: 774545-1

Used in Medicines

Country/Region:

Turkmenistan; Algeria; India; Lebanon; Jordan; China; Iraq

Traditional Medicine System:

Indian Folk; TCM; Unani; Ayurveda; Siddha

Medicinal Functions:

Abortifacient; Alterative; Aphrodisiac; Digestive; Diuretic; Emmenagogue; Galactogogue; Hallucinogenic; Miscellany; Narcotic; Ophthalmic; Parasiticide; Uterine tonic; Vermifuge

Geographical Distribution

Turkey; Italy; Bangladesh; India; France; Turkmenistan; Saudi Arabia; Algeria; Jordan; China; Iraq; Spain; Ukraine; Libya; United States; Morocco; Russia; Bulgaria; Pakistan; Romania; South Africa; Egypt; Lebanon; Tunisia; Greece; Hungary

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

54 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

49 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)