CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Gentiana Scabra

Example Image

PLANiTS DNA barcode

Click for details-----ITS2

Taxonomic Information

Plant ID: NPO10429
Plant Latin Name: Gentiana Scabra
Taxonomy Genus: Gentiana
Taxonomy Family: Gentianaceae

Plant External Links:

NCBI TaxonomyDB: 292393
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:

South Korea; China

Traditional Medicine System:

TCM; Kampo

Medicinal Functions:

Anodyne; Anthelmintic; Antiinflammatory; Antiseptic; Bitter; Cholagogue; Emmenagogue; Expectorant; Febrifuge; Pectoral; Refrigerant; Stomachic; Tonic

Geographical Distribution

South Korea; China

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

43 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

19 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)