Collective Molecular Activities of the Plant: Larix Cajanderi
Plant ID: NPO10389
Plant Latin Name: Larix Cajanderi
Taxonomy Genus: Larix
Taxonomy Family: Pinaceae
Plant External Links:
NCBI TaxonomyDB:
501393
Plant-of-the-World-Online:
n.a.
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
130 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
30 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
42 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC9860
Ingredient ID: NPC95610
Ingredient ID: NPC95062
Ingredient ID: NPC94659
Ingredient ID: NPC92117
Ingredient ID: NPC91955
Ingredient ID: NPC86655
Ingredient ID: NPC86136
Ingredient ID: NPC83291
Ingredient ID: NPC83189
Ingredient ID: NPC7447
Ingredient ID: NPC73483
Ingredient ID: NPC72468
Ingredient ID: NPC71195
Ingredient ID: NPC68324
Ingredient ID: NPC66718
Ingredient ID: NPC61341
Ingredient ID: NPC59593
Ingredient ID: NPC58877
Ingredient ID: NPC55098
Ingredient ID: NPC53757
Ingredient ID: NPC50315
Ingredient ID: NPC47933
Ingredient ID: NPC47826
Ingredient ID: NPC47521
Ingredient ID: NPC47234
Ingredient ID: NPC46274
Ingredient ID: NPC43918
Ingredient ID: NPC3474
Ingredient ID: NPC32109
Ingredient ID: NPC311389
Ingredient ID: NPC310581
Ingredient ID: NPC309701
Ingredient ID: NPC306397
Ingredient ID: NPC301077
Ingredient ID: NPC300911
Ingredient ID: NPC29549
Ingredient ID: NPC29506
Ingredient ID: NPC284934
Ingredient ID: NPC284752
Ingredient ID: NPC283506
Ingredient ID: NPC283174
Ingredient ID: NPC282818
Ingredient ID: NPC280008
Ingredient ID: NPC279943
Ingredient ID: NPC27871
Ingredient ID: NPC278127
Ingredient ID: NPC277686
Ingredient ID: NPC276202
Ingredient ID: NPC275048
Ingredient ID: NPC273789
Ingredient ID: NPC272844
Ingredient ID: NPC271482
Ingredient ID: NPC270797
Ingredient ID: NPC267627
Ingredient ID: NPC26703
Ingredient ID: NPC266580
Ingredient ID: NPC263583
Ingredient ID: NPC261623
Ingredient ID: NPC259866
Ingredient ID: NPC257546
Ingredient ID: NPC256766
Ingredient ID: NPC256392
Ingredient ID: NPC254168
Ingredient ID: NPC25389
Ingredient ID: NPC250436
Ingredient ID: NPC248995
Ingredient ID: NPC24627
Ingredient ID: NPC245827
Ingredient ID: NPC245240
Ingredient ID: NPC239943
Ingredient ID: NPC238400
Ingredient ID: NPC233210
Ingredient ID: NPC232622
Ingredient ID: NPC232364
Ingredient ID: NPC230818
Ingredient ID: NPC228715
Ingredient ID: NPC225710
Ingredient ID: NPC22451
Ingredient ID: NPC224281
Ingredient ID: NPC222930
Ingredient ID: NPC222183
Ingredient ID: NPC221870
Ingredient ID: NPC219876
Ingredient ID: NPC218736
Ingredient ID: NPC215875
Ingredient ID: NPC212031
Ingredient ID: NPC209434
Ingredient ID: NPC20791
Ingredient ID: NPC201814
Ingredient ID: NPC200119
Ingredient ID: NPC195380
Ingredient ID: NPC186628
Ingredient ID: NPC184318
Ingredient ID: NPC180474
Ingredient ID: NPC178134
Ingredient ID: NPC176740
Ingredient ID: NPC172419
Ingredient ID: NPC170034
Ingredient ID: NPC169749
Ingredient ID: NPC165382
Ingredient ID: NPC161066
Ingredient ID: NPC160512
Ingredient ID: NPC155525
Ingredient ID: NPC153031
Ingredient ID: NPC148358
Ingredient ID: NPC142393
Ingredient ID: NPC141361
Ingredient ID: NPC14030
Ingredient ID: NPC138118
Ingredient ID: NPC137698
Ingredient ID: NPC136859
Ingredient ID: NPC136464
Ingredient ID: NPC135222
Ingredient ID: NPC133821
Ingredient ID: NPC132250
Ingredient ID: NPC128792
Ingredient ID: NPC128484
Ingredient ID: NPC125062
Ingredient ID: NPC123316
Ingredient ID: NPC122818
Ingredient ID: NPC118502
Ingredient ID: NPC116850
Ingredient ID: NPC116775
Ingredient ID: NPC111490
Ingredient ID: NPC108776
Ingredient ID: NPC108455
Ingredient ID: NPC106574
Ingredient ID: NPC106071
Ingredient ID: NPC104222
Classification of Human Proteins Collectively Targeted by the Plant
Detailed Information of Target Proteins
| Target Type | Protein Class | Gene ID | Protein Name | Uniprot ID | Target ChEMBL ID |
|---|---|---|---|---|---|
| Drug Transporter | ATP-binding cassette | ABCB1 | P-glycoprotein 1 | P08183 | CHEMBL4302 |
| Therapeutic Target | Cysteine protease | CASP6 | Caspase-6 | P55212 | CHEMBL3308 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A1 | Cytochrome P450 1A1 | P04798 | CHEMBL2231 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1B1 | Cytochrome P450 1B1 | Q16678 | CHEMBL4878 |
| Cytochrome P450 | Cytochrome P450 family 1 | CYP1A2 | Cytochrome P450 1A2 | P05177 | CHEMBL3356 |
| Therapeutic Target | DNA methyltransferase | DNMT1 | DNA (cytosine-5)-methyltransferase 1 | P26358 | CHEMBL1993 |
| Therapeutic Target | Enzyme | RECQL | ATP-dependent DNA helicase Q1 | P46063 | CHEMBL1293236 |
| Therapeutic Target | Enzyme | ALOX12 | Arachidonate 12-lipoxygenase | P18054 | CHEMBL3687 |
| Therapeutic Target | Enzyme | POLB | DNA polymerase beta | P06746 | CHEMBL2392 |
| Therapeutic Target | Enzyme | NOX4 | NADPH oxidase 4 | Q9NPH5 | CHEMBL1250375 |
| Therapeutic Target | Enzyme | HPGD | 15-hydroxyprostaglandin dehydrogenase [NAD+] | P15428 | CHEMBL1293255 |
| Therapeutic Target | Enzyme | APEX1 | DNA-(apurinic or apyrimidinic site) lyase | P27695 | CHEMBL5619 |
| Therapeutic Target | Hydrolase | ACHE | Acetylcholinesterase | P22303 | CHEMBL220 |
| Therapeutic Target | Isomerase | TOP2A | DNA topoisomerase II alpha | P11388 | CHEMBL1806 |
| Therapeutic Target | Lyase | CA4 | Carbonic anhydrase IV | P22748 | CHEMBL3729 |
| Therapeutic Target | Lyase | CA2 | Carbonic anhydrase II | P00918 | CHEMBL205 |
| Therapeutic Target | Lyase | GLO1 | Glyoxalase I | Q04760 | CHEMBL2424 |
| Therapeutic Target | Lyase | CA12 | Carbonic anhydrase XII | O43570 | CHEMBL3242 |
| Therapeutic Target | Lyase | CA7 | Carbonic anhydrase VII | P43166 | CHEMBL2326 |
| Therapeutic Target | Lysine demethylase | KDM4E | Lysine-specific demethylase 4D-like | B2RXH2 | CHEMBL1293226 |
| Therapeutic Target | Methyl-lysine/arginine binding protein | L3MBTL1 | Lethal(3)malignant brain tumor-like protein 1 | Q9Y468 | CHEMBL1287622 |
| Therapeutic Target | Miscellaneous ion channel | BCL2 | Apoptosis regulator Bcl-2 | P10415 | CHEMBL4860 |
| Therapeutic Target | Other cytosolic protein | HSPA1A | Heat shock 70 kDa protein 1 | P0DMV8 | CHEMBL5460 |
| Therapeutic Target | Other nuclear protein | RAD52 | DNA repair protein RAD52 homolog | P43351 | CHEMBL2362978 |
| Therapeutic Target | Oxidoreductase | PGD | 6-phosphogluconate dehydrogenase | P52209 | CHEMBL3404 |
| Therapeutic Target | Oxidoreductase | HSD17B10 | Endoplasmic reticulum-associated amyloid beta-peptide-binding protein | Q99714 | CHEMBL4159 |
| Therapeutic Target | Oxidoreductase | AKR1B1 | Aldose reductase | P15121 | CHEMBL1900 |
| Therapeutic Target | Oxidoreductase | HSD17B2 | Estradiol 17-beta-dehydrogenase 2 | P37059 | CHEMBL2789 |
| Therapeutic Target | Peptide receptor (family A GPCR) | NPSR1 | Neuropeptide S receptor | Q6W5P4 | CHEMBL5162 |
| Therapeutic Target | Phosphodiesterase | TDP1 | Tyrosyl-DNA phosphodiesterase 1 | Q9NUW8 | CHEMBL1075138 |
| Therapeutic Target | Protein Kinase | CDK1 | Cyclin-dependent kinase 1 | P06493 | CHEMBL308 |
| Therapeutic Target | Protein Kinase | FLT3 | Tyrosine-protein kinase receptor FLT3 | P36888 | CHEMBL1974 |
| Therapeutic Target | Protein Kinase | TEK | Tyrosine-protein kinase TIE-2 | Q02763 | CHEMBL4128 |
| Therapeutic Target | Protein Kinase | NUAK1 | NUAK family SNF1-like kinase 1 | O60285 | CHEMBL5784 |
| Therapeutic Target | Protein Kinase | CSNK2A1 | Casein kinase II alpha | P68400 | CHEMBL3629 |
| Therapeutic Target | Protein Kinase | EGFR | Epidermal growth factor receptor erbB1 | P00533 | CHEMBL203 |
| Therapeutic Target | Protein Kinase | MET | Hepatocyte growth factor receptor | P08581 | CHEMBL3717 |
| Therapeutic Target | Protein Kinase | AXL | Tyrosine-protein kinase receptor UFO | P30530 | CHEMBL4895 |
| Therapeutic Target | Protein Kinase | PIM1 | Serine/threonine-protein kinase PIM1 | P11309 | CHEMBL2147 |
| Therapeutic Target | Protein Kinase | INSR | Insulin receptor | P06213 | CHEMBL1981 |
| Therapeutic Target | Protein Kinase | SRC | Tyrosine-protein kinase SRC | P12931 | CHEMBL267 |
| Therapeutic Target | Protein Kinase | YES1 | Tyrosine-protein kinase YES | P07947 | CHEMBL2073 |
| Therapeutic Target | Protein Kinase | IGF1R | Insulin-like growth factor I receptor | P08069 | CHEMBL1957 |
| Therapeutic Target | Protein Kinase | KDR | Vascular endothelial growth factor receptor 2 | P35968 | CHEMBL279 |
| Therapeutic Target | Protein Kinase | AURKB | Serine/threonine-protein kinase Aurora-B | Q96GD4 | CHEMBL2185 |
| Therapeutic Target | Protein Kinase | DYRK1A | Dual-specificity tyrosine-phosphorylation regulated kinase 1A | Q13627 | CHEMBL2292 |
| Therapeutic Target | Serine protease | F10 | Coagulation factor X | P00742 | CHEMBL244 |
| Therapeutic Target | Serine protease | F2 | Thrombin | P00734 | CHEMBL204 |
| Drug Transporter | SLC superfamily of solute carriers | SLC22A6 | Solute carrier family 22 member 6 | Q4U2R8 | CHEMBL1641347 |
| Therapeutic Target | Small molecule receptor (family A GPCR) | GPR35 | G-protein coupled receptor 35 | Q9HC97 | CHEMBL1293267 |
| Therapeutic Target | Structural protein | LMNA | Prelamin-A/C | P02545 | CHEMBL1293235 |
| Therapeutic Target | Threonine protease | PSMB5 | Proteasome Macropain subunit MB1 | P28074 | CHEMBL4662 |
| Therapeutic Target | Transcription factor | SMAD3 | Mothers against decapentaplegic homolog 3 | P84022 | CHEMBL1293258 |
| Therapeutic Target | Transcription factor | AHR | Aryl hydrocarbon receptor | P35869 | CHEMBL3201 |
| Therapeutic Target | Transferase | FUT7 | Alpha-(1,3)-fucosyltransferase 7 | Q11130 | CHEMBL3596077 |
| Therapeutic Target | Transferase | POLH | DNA polymerase eta | Q9Y253 | CHEMBL5542 |
| Therapeutic Target | Transferase | POLI | DNA polymerase iota | Q9UNA4 | CHEMBL5391 |
Clinical trials associated with plant from natural product (NP) & plant level:
| Clinical trials type | Number of clinical trials | |
|---|---|---|
 NP level | 101 | |
| NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
|---|---|---|---|---|
| NCT01394796 | Egcg, a dyrk1a Inhibitor as Therapeutic Tool for Reversing Cognitive Deficits in Down Syndrome Individuals. | Down syndrome | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02213094 | Phase I Study of Nicotinamide for Early Onset Preeclampsia | preeclampsia | Niacinamide (NPC306397) | NP level |
| NCT04011618 | Effect of Ellagic Ácid on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion | metabolic syndrome | Ellagic Acid (NPC178134) | NP level |
| NCT00088946 | Erlotinib and Green Tea Extract (Polyphenon® E) in Preventing Cancer Recurrence in Former Smokers Who Have Undergone Surgery for Bladder Cancer | urinary bladder cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00917735 | Green Tea and Reduction of Breast Cancer Risk | breast cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02226484 | Can Quercetin Increase Claudin-4 and Improve Esophageal Barrier Function in GERD? | gastroesophageal reflux disease | Quercetin (NPC20791) | NP level |
| NCT03268902 | Early Life Interventions for Childhood Growth and Development In Tanzania | malnutrition | Niacinamide (NPC306397) | NP level |
| NCT00625391 | Green Tea and Tai Chi for Bone Health | osteoporosis | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00707252 | Study of Polyphenon E in Addition to Erlotinib in Advanced Non Small Cell Lung Cancer | non-small cell lung carcinoma | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00449982 | Efficacy and Safety Study of Polyphenon E to Treat External Genital Warts | anogenital venereal wart | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02731495 | Effect of Epigallocatechin -3-gallate Supplementation in Traumatic Brain Injury Patients | brain injury | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02015312 | A Trial for the Treatment of Cardiac AL-Amyloidosis With the Green Tea Compound Epigallocatechin-3-gallate (TAME-AL) | AL amyloidosis | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00516243 | Defined Green Tea Catechin Extract in Treating Women With Hormone Receptor Negative Stage I-III Breast Cancer | breast cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00676780 | Green Tea Extract and Prostate Cancer | prostate cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01744587 | Epstein-Barr Virus Reactivation and the Effect of EGCG on Virus Reactivation in Remission Patients | nasopharyngeal neoplasm | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT05062486 | A Study to Evaluate the Safety and Efficacy of RQC for AMD | age-related macular degeneration | Quercetin (NPC20791) | NP level |
| NCT01720147 | Quercetin in Children With Fanconi Anemia; a Pilot Study | Fanconi anemia | Quercetin (NPC20791) | NP level |
| NCT01381354 | Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS) | multiple sclerosis | Niacinamide (NPC306397) | NP level |
| NCT01708278 | Beneficial Effects of Quercetin in Chronic Obstructive Pulmonary Disease (COPD) | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT02627898 | Effect of Green Tea Extract on Arterial Stiffness in Type 2 Diabetes Mellitus | type 2 diabetes mellitus | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01699711 | Normalization of dyrk1A and APP Function as an Approach to Improve Cognitive Performance and Decelerate AD Progression in DS Subjects: Epigallocatechin Gallate as Therapeutic Tool | Down syndrome | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01855971 | "Using Epigallocatechin Gallate (EGCG) and Cognitive Training to Modulate Cognitive Performance in Patients With Fragile X Syndrome" (TESFX) | fragile X syndrome | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00508885 | The Effect of Oral Niacinamide on Plasma Phosphorus Levels in Peritoneal Dialysis Patients | Hyperphosphatemia | Niacinamide (NPC306397) | NP level |
| NCT00799890 | Sunphenon in Progressive Forms of Multiple Sclerosis | multiple sclerosis | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00005828 | Green Tea Extract in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy | prostate cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00676793 | A Study of the Effect of Polyphenon E (Green Tea Extract) on Breast Cancer Progression | breast cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01340599 | Defined Green Tea Catechin Extract in Treating Patients With Localized Prostate Cancer Undergoing Surgery | prostate cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00233935 | Defined Green Tea Catechin Extract in Preventing Esophageal Cancer in Patients With Barrett's Esophagus | Barrett's esophagus | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT04055818 | A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease | sickle cell anemia | Niacinamide (NPC306397) | NP level |
| NCT00525668 | Sunphenon Epigallocatechin-gallate (EGCg) in Relapsing-remitting Multiple Sclerosis (SuniMS Study) | relapsing-remitting multiple sclerosis | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT03928847 | Fibroblast Specific Inhibition of LOXL2 and TGFbeta1 Signaling in Patients With Pulmonary Fibrosis. | idiopathic pulmonary fibrosis | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00316472 | The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients | Hyperphosphatemia | Niacinamide (NPC306397) | NP level |
| NCT01589809 | Effect of Nicotinamide in Friedreich's Ataxia | neurodegenerative disease | Niacinamide (NPC306397) | NP level |
| NCT00363805 | Green Tea or Polyphenon E in Preventing Lung Cancer in Former Smokers With Chronic Obstructive Pulmonary Disease | lung cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT04177693 | Pharmacokinetics and Hepatic Safety of EGCG | uterine fibroid | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01912820 | Effect of Quercetin on Green Tea Polyphenol Uptake in Prostate Tissue From Patients With Prostate Cancer Undergoing Surgery | prostate adenocarcinoma | Quercetin (NPC20791);Epigalocatechin Gallate (NPC250436) | NP level |
| NCT04898023 | Zinc and Green Tea Extract for Community Respiratory Viral Infections | viral disease | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00951834 | Sunphenon EGCg (Epigallocatechin-Gallate) in the Early Stage of Alzheimer´s Disease | Alzheimer disease | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00951964 | Treatment of Epidermolysis Bullosa Dystrophica by Polyphenon E (Epigallocatechin 3 Gallate) | Dystrophic epidermolysis bullosa | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02416739 | Anticancer Activity of Nicotinamide on Lung Cancer | non-small cell lung carcinoma | Niacinamide (NPC306397) | NP level |
| NCT02848131 | Senescence in Chronic Kidney Disease | chronic kidney disease | Quercetin (NPC20791) | NP level |
| NCT00003197 | Green Tea Extract in Treating Patients With Advanced Solid Tumors | neoplasm | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01375101 | Therapeutic Effect of Quercetin and the Current Treatment of Erosive and Atrophic Oral Lichen Planus | oral lichen planus | Quercetin (NPC20791) | NP level |
| NCT00596011 | Study of Polyphenon E in Men With High-grade Prostatic Intraepithelial Neoplasia | benign prostatic hyperplasia | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT03419364 | Study of Nicotinamide in Early Onset Preeclampsia | preeclampsia | Niacinamide (NPC306397) | NP level |
| NCT00461942 | Efficacy and Safety of Green Tea Polyphenol in De Novo Parkinson's Disease Patients | Parkinson disease | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01183767 | Sunphenon Epigallocatechin-Gallate (EGCg) in Duchenne Muscular Dystrophy | Duchenne muscular dystrophy | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01433289 | Study to Evaluate Safety and Toxicity of Polyphenon E (EGCG) in HIV-1-Infected Individuals | HIV infection | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT03989271 | Biological Effects of Quercetin in COPD | chronic obstructive pulmonary disease | Quercetin (NPC20791) | NP level |
| NCT02558595 | Pilot Study of Niacinamide in Polycystic Kidney Disease (NIAC-PKD2) | Polycystic Kidney Disease | Niacinamide (NPC306397) | NP level |
| NCT00836719 | Safety of Polyphenon E in Multiple Sclerosis Pilot Study | multiple sclerosis | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00091325 | Green Tea Extract (Polyphenon E) in Preventing Cancer in Healthy Participants | neoplasm | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT03943459 | Sirtuin-1 and Advanced Glycation End-products in Postmenopausal Women With Coronary Disease | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT01368887 | Study to Test the Effectiveness of a New Treatment for Scalp Psoriasis | psoriasis | Niacinamide (NPC306397) | NP level |
| NCT00262743 | Green Tea Extract in Treating Patients With Stage 0, Stage I, or Stage II Chronic Lymphocytic Leukemia | leukemia | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT05422885 | Safety and Feasibility of Dasatinib and Quercetin in Adults at Risk for Alzheimer's Disease | aging | Quercetin (NPC20791) | NP level |
| NCT04843553 | Nicotinamide for Prevention of Pre-malignant Actinic Keratosis in Kidney Transplant Recipients | actinic keratosis | Niacinamide (NPC306397) | NP level |
| NCT05276895 | Effect of Natural Senolytic Agents & NLRP3 Inhibitors on Osteoarthritis | osteoarthritis | Quercetin (NPC20791) | NP level |
| NCT01705652 | Study to Assess the Activity of Nexrutine® in Prostate Cancer Patients | prostate cancer | Rutin (NPC176740) | NP level |
| NCT00455416 | Dietary Intervention in Follicular Lymphoma | follicular lymphoma | Epigalocatechin Gallate (NPC250436);Quercetin (NPC20791);Ellagic Acid (NPC178134) | NP level |
| NCT03769285 | Skin Cancer Prevention With Nicotinamide in Transplant Recipients - Pilot Trial | basal cell carcinoma;squamous cell carcinoma | Niacinamide (NPC306397) | NP level |
| NCT04844528 | Effects of Nicotinamide in Patients With Chronic Lymphocytic Leukemia (CLL) With History of Non-melanoma Skin Cancers (NMSC) | chronic lymphocytic leukemia | Niacinamide (NPC306397) | NP level |
| NCT00691210 | Phase I Vorinostat in Combination With Niacinamide and Etoposide for Lymphoid Malignancies | Hodgkins lymphoma;non-Hodgkins lymphoma | Niacinamide (NPC306397) | NP level |
| NCT04553666 | Reducing Frailty for Older Cancer Survivors Using Supplements | inflammation | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT04649203 | Cytoflavin in the Treatment of Patients With Diabetic Polyneuropathy | diabetic neuropathy | Niacinamide (NPC306397) | NP level |
| NCT04670081 | Efficacy and Safety of Psilocybin in Treatment-Resistant Major Depression | depressive disorder | Niacinamide (NPC306397) | NP level |
| NCT00666562 | Green Tea Extract in Treating Patients With Nonmetastatic Bladder Cancer | urinary bladder cancer | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01348204 | Nasal Potential Studies Utilizing Cystic Fibrosis Transmembrane Regulator (CFTR) Modulators | cystic fibrosis | Quercetin (NPC20791) | NP level |
| NCT00942422 | Green Tea Extract in Treating Patients With Monoclonal Gammopathy of Undetermined Significance and/or Smoldering Multiple Myeloma | multiple myeloma | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02329600 | Evaluation of Green Tea as Antioxidant Agent in Management of Oral Lichen Planus | oral lichen planus | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT03418935 | Remaxol® in Mechanical Jaundice of Non-malignant Origin | obstructive jaundice | Niacinamide (NPC306397) | NP level |
| NCT03626298 | Efficacy and Tolerability of Nicotinamide Plus Cream for Moderate Acne Vulgaris in Indonesia | acne | Niacinamide (NPC306397) | NP level |
| NCT00033436 | Radiation Therapy With or Without Carbogen and Niacinamide in Treating Patients With Bladder Cancer | urinary bladder cancer | Niacinamide (NPC306397) | NP level |
| NCT04851821 | The Effectiveness of Phytotherapy in SARS-COV2(COVID-19) | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT01357681 | Effects of EGCG (Epigallocatechin Gallate) in Huntington's Disease (ETON-Study) | Huntington disease | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02008721 | Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-Approach | multiple system atrophy | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT00567905 | Effect of Green Tea Extract on Type 2 Diabetes | type 2 diabetes mellitus | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT05364008 | FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate | uterine fibroid | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT03761511 | Study of the Efficacy and Safety of Nicotinamide in Patients With Friedreich Ataxia | Friedreich ataxia | Niacinamide (NPC306397) | NP level |
| NCT00580931 | Safety Study of Nicotinamide to Treat Alzheimer's Disease | Alzheimer disease | Niacinamide (NPC306397) | NP level |
| NCT02891538 | Chemopreventive Effects of Epigallocatechin Gallate (EGCG) in Colorectal Cancer (CRC) Patients | malignant colon neoplasm | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02258074 | The COMBINE Study: The CKD Optimal Management With BInders and NicotinamidE | chronic kidney disease | Niacinamide (NPC306397) | NP level |
| NCT04853199 | Quercetin In The Treatment Of SARS-COV 2 | COVID-19 | Quercetin (NPC20791) | NP level |
| NCT04870866 | NAD Supplementation to Prevent Progressive Neurological Disease in Ataxia Telangiectasia | Ataxia-telangiectasia | Niacinamide (NPC306397) | NP level |
| NCT01060345 | A Pilot Study of Chemo-prevention of Green Tea in Women With Ductal Carcinoma in Situ | breast ductal carcinoma in situ | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT04733534 | An Open-Label Intervention Trial to Reduce Senescence and Improve Frailty in Adult Survivors of Childhood Cancer | childhood cancer | Quercetin (NPC20791) | NP level |
| NCT00459407 | Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate | prostate adenocarcinoma | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT02875691 | Effect of Green Tea on Treatment of Lupus | systemic lupus erythematosus | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT04907253 | Quercetin in Coronary Artery By-pass Surgery | coronary artery disease | Quercetin (NPC20791) | NP level |
| NCT05456022 | Therapeutic Efficacy of Quercetin Versus Its Encapsulated Nanoparticle on Tongue Squamous Cell Carcinoma Cell Line | mouth neoplasm | Quercetin (NPC20791) | NP level |
| NCT04946383 | Safety and Effectivness of Quercetin & Dasatinib on Epigenetic Aging | aging | Quercetin (NPC20791) | NP level |
| NCT02140814 | Uncontrolled, Open Label, Pilot and Feasibility Study of Niacinamide in Polycystic Kidney Disease | Polycystic Kidney Disease | Niacinamide (NPC306397) | NP level |
| NCT01451723 | Safety and Neuroprotective Effects of Polyphenon E in MS | multiple sclerosis | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT03260166 | Nicotinamide Treatment for Lupus-associated Skin Lesions in Lupus Erythematosus | cutaneous lupus erythematosus;systemic lupus erythematosus | Niacinamide (NPC306397) | NP level |
| NCT02701127 | Molecular Effects of Vitamin B3 (Niacinamide) in Acute Kidney Injury | Acute kidney injury | Niacinamide (NPC306397) | NP level |
| NCT01438320 | Q-Trial in Patients With Hepatitis C | chronic hepatitis C virus infection | Quercetin (NPC20791) | NP level |
| NCT03392623 | DNA Methylation in Malar Melasma and Its Change by Sunscreen, Retinoic Acid and Niacinamide. | freckles | Niacinamide (NPC306397) | NP level |
| NCT03278925 | Defined Green Tea Catechin Extract in Preventing Liver Cancer in Participants With Cirrhosis | cirrhosis of liver | Epigalocatechin Gallate (NPC250436) | NP level |
| NCT01011699 | Nicotinamide Versus Sevelamer Hydrochloride on Phosphatemia Control on Chronic Hemodialysed Patients | chronic kidney disease | Niacinamide (NPC306397) | NP level |
| NCT01839344 | Effects of Quercetin on Blood Sugar and Blood Vessel Function in Type 2 Diabetes. | type 2 diabetes mellitus | Quercetin (NPC20791) | NP level |
| NCT02832271 | Green Tea Extract for Endometriosis Treatment | endometriosis | Epigalocatechin Gallate (NPC250436) | NP level |
❱❱❱ Associated Human Diseases and Detailed Association Evidence
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
|---|---|
Malignant haematopoietic neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33 |
IL6,TP53,DPP4,TOP2A,AURKB,CDK1,SRC,FLT3,BCL2
|
Malignant neoplasms of oesophagusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TERT,HSPA1A,NPSR1,AURKB,NOX4,TOP2A,ACHE,CDK1,ALOX15
|
Myelodysplastic syndromeDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A37 |
KDR,TERT,AHR,AXL,TP53,EGFR,BCL2,DNMT1
|
Stomach cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72 |
TP53,TOP2A,BCL2,EGFR,KDR,HSPA1A,HSPA1B,MET
|
Colorectal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B91 |
KDR,TP53,FLT3,TOP2A,TERT,EGFR,IGF1R,MET
|
Pancreatic cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10 |
TP53,EGFR,BCL2,TOP2A,SRC,DNMT1,IGF1R,TERT
|
Ovarian cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73 |
BCL2,SRC,TERT,TP53,MET,TOP2A,KDR,FLT3
|
Urothelial carcinoma of bladderDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.2 |
TERT,AKR1B1,AURKB,TOP2A,CA2,CYP2C9,CYP1A2,CDK1
|
Malignant neoplasms of thyroid gland, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10.Z |
ALOX5,CYP1B1,NOX4,CA12,DPP4,MET,XDH,CA7
|
Renal cell carcinoma, chromophobe typeDisease Category: X.Extension CodesDisease ICD-11 Code: XH6153 |
CYP1A2,TERT,CA12,CA2,CYP1A1,AURKB,TOP2A,MET
|
PsoriasisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA90 |
DPP4,AHR,FLT3,ALOX5,TOP2A,BCL2
NCT01368887 |
Brain cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00 |
KDR,TERT,MET,TP53,TOP2A,SRC,EGFR
|
Liver cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12 |
IGF1R,KDR,MET,TOP2A,TERT,CSNK2A1,EGFR
|
Multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40 |
SRC,TOP2A,F2
NCT01451723,NCT01381354,NCT00799890,NCT00836719 |
Prostate cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82 |
TERT,AURKB,BCL2
NCT00676780,NCT00005828,NCT01340599,NCT01705652 |
Melanoma of skinDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
TERT,IGF1R,FUT7,ABCG2,NOX4,BCL2,APP
|
Invasive carcinoma of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C61 |
TERT,FUT7,AURKB,TOP2A,CA12,ELAVL3,CDK1
|
Carpal tunnel syndromeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C10.0 |
FUT7,CYP1B1,NOX4,ANTXR2,IL6,DPP4,SMAD3
|
GlaucomaDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C61 |
ACHE,MET,CA4,AKR1B1,TERT,CA2
|
Bacterial infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-1C4Z |
CA12,CA4,CA2,CYP2C9,TOP2A,ABCB1
|
Myeloproliferative neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A20 |
TERT,TEK,FLT3,DNMT1,SRC,BCL2
|
Type 2 diabetes mellitusDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A11 |
DPP4,F2,INSR
NCT00567905,NCT02627898,NCT01839344 |
MelanomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C30 |
TYR,MET,KDR,BCL2,TERT,EGFR
|
West Nile virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D46 |
CYP19A1,IL6,DPP4,ACHE,MET,AXL
|
Other specified malignant neoplasms ofcolonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90.Y |
NPSR1,NOX4,TYR,CYP1A1,F2,MET
|
Chikungunya virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D40 |
CYP19A1,XDH,EGFR,GPR35,LMNA,AXL
|
BCR-ABL1-negative chronic myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A41 |
SRC,BCL2,HSPA1B,HSPA1A,FLT3
|
Mature B-cell leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82 |
SRC,AXL,TP53,BCL2,EGFR
|
Mature B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A85 |
TEK,BCL2,CDK1,TOP2A,FLT3
|
Motor neuron diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B60 |
IGF1R,HSPA1B,SRC,HSPA1A,BCL2
|
Rheumatoid arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA20 |
ABCG2,AKR1B1,IL6,ALOX5,CA2
|
Acute diabete complicationDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A2Y |
INSR,AKR1B1,AURKB,KDR,DPP4
|
Head and neck cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D42 |
TERT,TP53,EGFR,KDR,MET
|
Non-small cell lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
KDR,MET,EGFR
NCT00707252,NCT02416739 |
Pain, unspecifiedDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG3Z |
IGF1R,AKR1B1,ALOX5,INSR,ACHE
|
Chronic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB61 |
XDH,IGF1R
NCT02258074,NCT01011699,NCT02848131 |
Adenocarcinoma of prostateDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C82.0 |
TERT,NOX4,ALOX15
NCT01912820,NCT00459407 |
Systemic lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40.0 |
CYP1A1,YES1,ACHE
NCT03260166,NCT02875691 |
LeishmaniasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F54 |
FUT7,AKR1B1,NOX4,DPP4,FLT3
|
Malignant neoplasm metastasis in lymph nodes of head, face or neckDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60.0 |
TERT,NPSR1,AURKB,NOX4,F2
|
Other specified malignant neoplasms of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.Y |
AURKB,TOP2A,CA12,CDK1,XDH
|
Human immunodeficiency virus disease without mention of tuberculosis or malariaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62 |
IL6,MET,FLT3,GPR35,AXL
|
ParkinsonismDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A00 |
SNCA,ACHE,SRC
NCT00461942 |
NeuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C0Z |
HSPA1A,HSPA1B,AKR1B1,CYP19A1
|
Malignant digestive organ neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C11 |
HSPA1A,SRC,HSPA1B,KDR
|
Peritoneal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C51 |
FLT3,SRC,KDR,TP53
|
Cardiovascular diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00-BE2Z |
MET,F2,SRC,KDR
|
RetinopathyDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B71 |
APEX1,TEK,APP,IGF1R
|
ThrombosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB61-GB90 |
AKR1B1,F10,F2,TOP2A
|
Diffuse large B-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
TOP2A,FLT3,BCL2,DNMT1
|
AsthmaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA23 |
CA4,TOP2A,F2,ALOX5
|
ThrombocytopeniaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B64 |
KDR,F2,AHR,ALOX5
|
Chronic arterial occlusive diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD4Z |
MET,TEK,TP53,DPP4
|
Zika virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D48 |
IL6,SMAD3,ACHE,AXL
|
Osteoarthritis, unspecifiedDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA0Z |
TOP2A,CA12,CDK1,HSD17B2
|
Ebola virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D60.01 |
HSD17B2,MET,ACHE,AXL
|
Mesothelioma of pleuraDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C26.0 |
KDR,FUT7,PGD,ALOX5,CSNK2A2,FLT3,CA7,ALOX15,TERT,BACE1,SNCA,PIM1,RECQL,CA12,DPP4,APEX1,EGFR,HPGD,SRC,POLH,TDP1,DNMT1,ABCB1,TYR,LMNA,AXL,HSD17B2,AHR,GALNT2,AURKB,TOP2A,MET,CDK1,XDH,CASP6
|
Diffuse large B-cell lymphomasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A81 |
HSD17B10,KDR,CSNK2A2,NOX4,BCL2,TEK,TERT,CSNK2A1,TP53,RECQL,IL6,CA12,GLO1,APEX1,EGFR,MAPKAPK5,CDK1,SRC,AKR1B1,POLH,CISD1,TDP1,DNMT1,LMNA,AXL,F10,AHR,AURKB,TOP2A,NUAK1,MET,ACHE,PSMB5,CASP6
|
Adenocarcinoma of pancreasDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C10.0 |
FUT7,PGD,CYP1B1,ALOX5,NPSR1,CYP2C9,ANTXR2,TEK,CA7,ALOX15,TERT,ABCG2,SNCA,XDH,PIM1,IL6,RECQL,DPP4,POLB,CA2,CISD1,ABCB1,LMNA,AXL,F10,HSD17B2,AURKB,F2,NUAK1,MET,ACHE,PGAM1,APP
|
Germ cell tumour of testisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80.2 |
KDR,FUT7,PGAM1,PGD,ALOX5,NPSR1,NOX4,CYP2C9,TEK,ABCG2,SNCA,XDH,IL6,CA12,ALOX12,DPP4,GLO1,CA4,HPGD,MAPKAPK5,AKR1B1,RAD52,HSD17B2,AHR,SMAD3,F2,NUAK1,MET,ACHE,CDK1,APP,SLC22A6,CASP6
|
Solid tumour/cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00-2F9Z |
SRC,BCL2,TEK,APEX1,AURKB,IGF1R,POLB,AHR,CDK1,MET,TP53,CA2,TOP2A,ALOX5,APP,YES1,DNMT1,HSPA1A,AXL,FLT3,KDR,CA12,TERT,PIM1,ABCB1,EGFR,CSNK2A1,CA4,HSPA1B,XDH
|
Renal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90 |
MET,EGFR,KDR
|
InfluenzaDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E30-1E32 |
ALOX5,XDH,GLO1
|
Seborrhoeic dermatitisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA81 |
CA12,CA4,CA2
|
Metastatic lymph node neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D60 |
EGFR,KDR,MET
|
Chronic painDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG30 |
FLT3,KDR,EGFR
|
Crohn diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD70 |
INSR,IL6
IL6 |
Follicular lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A80 |
TOP2A,BCL2
NCT00455416 |
Herpes simplex infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F00 |
SMAD3,HSPA1A,HSPA1B
|
Pituitary gland disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A60-5A61 |
IGF1R,PGD,ALOX5
|
Bladder cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94 |
TOP2A,TP53,DNMT1
|
Metastatic malignant neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D50-2E09 |
HSPA1A,HSPA1B,AXL
|
Nasopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
ALOX5,CDK1,EGFR
|
Pleomorphic sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B54 |
MET,SRC,KDR
|
NADisease Category: NADisease ICD-11 Code: NA |
NOX4,MET
NCT04553666 |
Diabetic foot ulcerDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD54 |
EGFR,HSPA1A,HSPA1B
|
Pre-eclampsiaDisease Category: 18.Pregnancy, childbirth or the puerperiumDisease ICD-11 Code: JA24 |
CA4
NCT03419364,NCT02213094 |
Malignant neoplasms of bladder, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C94.Z |
NCT00033436,NCT00666562,NCT00088946
|
Myotonic dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C71.0 |
CYP1A1,TOP2A,HPGD
|
Tetralogy of FallotDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LA88.2 |
ABCG2,F2,CA4
|
Polycystic ovary syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80.1 |
FUT7,POLH,HPGD
|
Gliomas of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.0 |
NOX4,ANTXR2,AHR
|
Serous cystadenoma,borderline malignancy of ovaryDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C73.4 |
FUT7,CSNK2A3,PGD,ALOX5,NOX4,CYP1A2,ALOX15,TERT,CSNK2A1,CA12,ALOX12,YES1,APEX1,GLO1,HPGD,POLH,CA2,CISD1,TDP1,DNMT1,HSD17B2,AHR,PSMB5,ELAVL3,MET,TP53,XDH,CASP6
|
Carcinosarcoma of uterusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.43 |
HSD17B10,FUT7,PGAM1,PGD,NPSR1,CA7,ALOX15,TERT,TP53,DPP4,YES1,GLO1,POLB,AKR1B1,CA2,CISD1,TDP1,HSD17B2,GALNT2,AURKB,CYP19A1,TOP2A,ELAVL3,MET,PSMB5,XDH,CASP6
|
Malignant neoplasms of biliary tract, distal bile ductDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C15 |
CSNK2A3,ALOX5,NOX4,BCL2,L3MBTL1,TERT,CSNK2A1,ALOX12,CA4,CDK1,SRC,AKR1B1,DNMT1,LMNA,IGF1R,SMAD3,AURKB,TOP2A,ELAVL3,NUAK1,TP53,GPR35
|
Thyroid cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D10 |
MET,KDR
|
Unspecific body region injuryDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: ND56 |
EGFR,MET
|
Coagulation defectDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B10 |
F2,F10
|
Atopic eczemaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA80 |
ALOX5,AHR
|
Diabetes mellitus, type unspecifiedDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A14 |
INSR,DPP4
|
Heart failureDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD10-BD1Z |
XDH,CA2
|
Chronic myelomonocytic leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A40 |
BCL2,FLT3
|
Metabolic disorderDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C50-5D2Z |
DPP4
NCT04011618 |
Idiopathic interstitial pneumonitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03 |
FLT3,ALOX5
|
Dystrophic epidermolysis bullosaDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EC32 |
APP
NCT00951964 |
Mature T-cell lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A90 |
EGFR,TOP2A
|
Cutaneous lupus erythematosusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EB50-EB5Z |
IL6
NCT03260166 |
Endometrial cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76 |
SRC,TP53
|
Postoperative inflammationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A00-CA43 |
ALOX5,SRC
|
Unspecified viral infection of unspecified siteDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D9Z |
FLT3
NCT04898023 |
Fallopian tube cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C74 |
TP53,SRC
|
IschemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B10-8B11 |
SRC,EGFR
|
Gastrointestinal stromal tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5B |
SRC,KDR
|
Coronary thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA43 |
F2,F10
|
EndometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10 |
CYP19A1
NCT02832271 |
Kaposi sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B57 |
TOP2A,DNMT1
|
Cervical cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C77 |
SRC,TP53
|
Angina pectorisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40 |
F2,EGFR
|
Myocardial infarctionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA41-BA43 |
DPP4,F2
|
Ovarian dysfunctionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A80 |
BCL2,TP53
|
Bleeding disorderDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA20-GA21 |
F10,F2
|
AmyloidosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5D00 |
APP
NCT02015312 |
Anogenital wartsDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A95 |
TOP2A
NCT00449982 |
Uterine fibroidDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E66 |
NCT05364008,NCT04177693
|
Autosomal dominant polycystic kidney diseaseDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB81 |
NCT02558595,NCT02140814
|
Lichen planusDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EA91 |
NCT01375101,NCT02329600
|
Chronic obstructive pulmonary diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA22 |
NCT03989271,NCT01708278
|
coronary artery diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA8Y-BA8Z |
NCT04907253,NCT03943459
|
COVID-19Disease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D6Y |
NCT04851821,NCT04853199
|
Complete trisomy 21Disease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD40.0 |
NCT01699711,NCT01394796
|
Disorders of calcium or phosphate excretionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB90.48 |
NCT00316472,NCT00508885
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT00003197,NCT00091325
|
Ageing associated decline in intrinsic capacityDisease Category: 21.Symptoms, signs or clinical findings, not elsewhere classifiedDisease ICD-11 Code: MG2A |
NCT04946383,NCT05422885
|
Coeliac diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA95 |
CDK1,CYP1A1
|
Myelodysplastic syndromes, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A3Z |
CYP2C9,PIM1
|
Inflammatory bowel diseases, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD7Z |
IL6,NOX4
|
Dengue fever, unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D2Z |
AURKB,ABCG2
|
Heart failure, unspecifiedDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD1Z |
CYP1B1,ABCG2
|
Hepatocellular carcinoma of liverDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.02 |
L3MBTL1,TERT,CYP19A1,AURKB,NOX4,TOP2A,CA12,DNMT1,CA4,CDK1,GPR35,SLC22A6,TERT,SRC,CYP19A1,AURKB,TOP2A,CA12,CDK1
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
SRC,CYP19A1,IGF1R,MET,BCL2,EGFR,TOP2A,AXL,CA4,CDK1,CA2,KDR,CA12,TEK,TERT
NCT00516243,NCT00917735,NCT00676793 |
Other specified malignant neoplasms of kidney, except renal pelvisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C90.Y |
ALOX5,CYP2C9,TERT,XDH,TYR,CYP19A1,AURKB,TOP2A,MET,ACHE,TERT,FUT7,ALOX5,AURKB,F2,TOP2A,GPR35
|
Malignant neoplasms of adrenal glandDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D11 |
FUT7,NOX4,CA7,TERT,SNCA,CA12,DPP4,GLO1,CA4,HPGD,HSD17B2,F10,AURKB,CYP19A1,TOP2A,MET,CDK1
|
Malignant neoplasms of thymusDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C27 |
HSD17B10,FUT7,CYP1B1,CYP2C9,FLT3,ALOX15,DPP4,APEX1,HPGD,AKR1B1,CISD1,DNMT1,HSD17B2,GALNT2,ACHE,PSMB5
|
Lung cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25 |
ALOX5,EGFR,TERT,AXL,MET,BCL2,KDR,DNMT1,CDK1,FLT3,TOP2A,ABCB1,IGF1R
NCT00363805 |
HepatoblastomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C12.01 |
NOX4,L3MBTL1,IL6,CA12,CA4,SRC,AKR1B1,GPR35,IGF1R,CYP19A1,AURKB,TOP2A,NUAK1,CDK1
|
Malignant neoplasms of corpus uteri, unspecifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C76.Z |
PGD,NPSR1,CYP2C9,ALOX15,TERT,XDH,CA2,HSD17B2,CYP1A1,AURKB,F2,TOP2A,CDK1,GPR35
|
PheochromocytomaDisease Category: X.Extension CodesDisease ICD-11 Code: XH3854 |
F10,FUT7,SNCA,NOX4,XDH,ELAVL3,BCL2,CA2,ACHE,CA4,MET,APP
|
Squamous cell carcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.2 |
PGD,NPSR1,CYP2C9,CA7,TERT,CA12,ALOX12,AURKB,F2,TOP2A,CDK1,XDH
|
Adenocarcinoma of bronchus or lungDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C25.0 |
NPSR1,CYP2C9,CA7,TERT,CA12,GPR35,AURKB,F2,TOP2A,ACHE,CDK1,XDH
|
Glioblastoma of brainDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A00.00 |
CSNK2A3,CYP1B1,ANTXR2,IL6,CA12,DPP4,POLH,CA2,LMNA,CYP19A1,MET,KDR
|
Alzheimer diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20 |
BACE1,FLT3,SNCA,APP,KDR,MET,TOP2A,ACHE,INSR
NCT00580931,NCT00951834 |
Multiple myelomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A83 |
BCL2,SRC,AXL,TERT,FLT3,AHR,IGF1R,INSR,KDR,IL6
NCT00942422 |
Acute myeloid leukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60 |
PIM1,FLT3,SRC,TERT,AXL,AURKB,TOP2A,BCL2,DNMT1,TP53
|
Adenocarcinoma of stomachDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B72.0 |
NPSR1,NOX4,ALOX15,TERT,CYP19A1,AURKB,F2,TOP2A,MET,CDK1
|
Superficial ovarian endometriosisDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA10.B4 |
F10,SRC,SNCA,DPP4,CA2,INSR,ACHE,CA4,PGAM1,LMNA
|
Cytomegaloviral diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D82 |
CYP1A1,KDM4E,CA2,ELAVL3,CYP2C9,ACHE,GPR35,ABCB1,HPGD,ALOX15
|
Irritable bowel syndromeDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD91 |
ABCG2
|
Respiratory system diseaseDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB40-CB7Z |
TOP2A
|
Venous thromboembolismDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD72 |
F10
|
Malignant mesenchymal neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5D-2B5Y |
EGFR
|
Blood-forming organ diseaseDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3C0Z |
F10
|
AnemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A00-3A9Z |
IL6
|
HIV-infected patients with tuberculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1B10-1B14 |
TOP2A
|
CataractDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B10 |
AKR1B1
|
Multiple structural anomalies syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2F |
IGF1R
|
Acquired hypermelanosisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED60 |
TYR
|
Psoriatic arthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA21 |
IL6
|
Metastatic biliary tract neoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C14-2C17 |
EGFR
|
Intracerebral haemorrhageDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B00 |
EGFR
|
Duodenal ulcerDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA63 |
CA2
|
ThrombocytosisDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B63 |
TERT
|
Myasthenia gravisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C6Y |
ACHE
|
OsteosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B51 |
SRC
|
Cerebral ischaemiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B1Z |
F10
|
Christmas diseaseDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3B11 |
F10
|
Inborn purine/pyrimidine/nucleotide metabolism errorDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C55 |
XDH
|
Cerebral ischaemic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B11 |
F2
|
EncephalopathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8E47 |
XDH
|
Substance abuseDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6C40 |
ACHE
|
OesophagitisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA24 |
CYP19A1
|
Digestive organ benign neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E92 |
KDR
|
Transplant rejectionDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE84 |
TP53
|
Urethral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C93 |
EGFR
|
Colon cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
EGFR
|
Metastatic liver/bile duct neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D80 |
TP53
|
Hepatitis virus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E50-1E51 |
EGFR
|
Deep vein thrombosisDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BD71 |
F10
|
Otitis mediaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA80-AB0Z |
TOP2A
|
Ocular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D00-2D07 |
APEX1
|
Biliary tract cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C17 |
MET
|
Gonococcal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A70-1A7Z |
TOP2A
|
Kidney failureDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60-GB6Z |
TP53
|
GoutDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA25 |
XDH
|
Bone/articular cartilage neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7B |
FLT3
|
Phakomatoses/hamartoneoplastic syndromeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD2D |
FLT3
|
Spinal cord/cranial nerve neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A02 |
EGFR
|
Lysosomal diseaseDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5C56 |
INSR
|
Synovial sarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B5A |
SRC
|
Liver diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB90-DB9Z |
MET
|
Autism spectrum disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A02 |
DPP4
|
Ischemic heart diseaseDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA40-BA6Z |
MET
|
Acquired hypomelanotic disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED63 |
TYR
|
Lip/oral cavity/pharynx neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6E |
TP53
|
FilariasisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F66 |
ALOX5
|
ThyrotoxicosisDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A02 |
IGF1R
|
PediculosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1G00 |
ACHE
|
Esophageal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B70 |
TP53
|
Urinary tract infectionDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GC08 |
TOP2A
|
MastocytosisDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A21 |
FLT3
|
Carcinoid syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B10 |
ALOX5
|
Human immunodeficiency virus diseaseDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C60-1C62 |
FLT3
|
ChemoprotectionDisease Category: NADisease ICD-11 Code: N.A. |
TOP2A
|
SyphilisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1A61-1A6Z |
TOP2A
|
Inflammatory arthropathyDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA2Z |
FLT3
|
LeiomyosarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B58 |
SRC
|
InsomniaDisease Category: 07.Sleep-wake disordersDisease ICD-11 Code: 7A00-7A0Z |
CA2
|
Transplanted organ/tissueDisease Category: 24.Factors influencing health status or contact with health servicesDisease ICD-11 Code: QB63 |
FLT3
|
Fungal infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F29-1F2F |
ALOX5
|
DementiaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D80-6D8Z |
ACHE
|
Oesophageal/gastroduodenal disorderDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DD90 |
ACHE
|
Attention deficit hyperactivity disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A05 |
F10
|
Coronavirus infectionDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1D92 |
CSNK2A1
|
Otitis externaDisease Category: 10.Diseases of the ear or mastoid processDisease ICD-11 Code: AA00-AA13 |
TOP2A
|
Common wartsDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E80 |
TOP2A
|
Hypopharyngeal cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6D |
EGFR
|
Extraocular muscle disorderDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9C82 |
IGF1R
|
Ischaemic/haemorrhagic strokeDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8B20 |
F2
|
Autonomic nervous system disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87 |
SNCA
|
Low bone mass disorderDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83 |
CA2
|
Essential hypertensionDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BA00 |
CA2
|
Unspecific substance harmful effectDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NE6Z |
ACHE
|
VasculitisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A44 |
IL6
|
LiposarcomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B59 |
TP53
|
Type-1/2 diabeteDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A10-5A11 |
INSR
|
SchizophreniaDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20 |
AKR1B1
|
Ureteral cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C92 |
AHR
|
Epidermal dysplasiasDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EK90 |
SRC
|
Lupus erythematosusDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A40 |
IL6
|
Supraventricular tachyarrhythmiaDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81 |
F10
|
Cushing syndromeDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5A70 |
CYP19A1
|
Nutritional deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B50-5B71 |
F2
|
Testicular cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C80 |
EGFR
|
Parasitic worm infestationDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1F90 |
ACHE
|
Mild neurocognitive disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6D71 |
ACHE
|
DepressionDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A70-6A7Z |
IL6
|
Mineral deficiencyDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B5K |
XDH
|
Skin postprocedural disorderDisease Category: 14.Diseases of the skinDisease ICD-11 Code: EL8Y |
EGFR
|
Metastatic digestive system neoplasmDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D8Y |
SRC
|
Desmoid tumourDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2F7C |
APP
|
Psychotic disorderDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A20-6A25 |
INSR
|
Diagnostic imagingDisease Category: NADisease ICD-11 Code: N.A. |
APP
|
Neurodegenerative disorderDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A20-8A23 |
NCT01589809
|
OsteoarthritisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FA00-FA05 |
NCT05276895
|
Idiopathic pulmonary fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CB03.4 |
NCT03928847
|
Acne vulgarisDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED80 |
NCT03626298
|
Huntington diseaseDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A01.10 |
NCT01357681
|
Duchenne muscular dystrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C70.1 |
NCT01183767
|
Chronic hepatitis CDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1E51.1 |
NCT01438320
|
Chronic lymphocytic leukaemia or small lymphocytic lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A82.0 |
NCT04844528
|
Congenital aplastic anaemiaDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A70.0 |
NCT01720147
|
Actinic keratosisDisease Category: X.Extension CodesDisease ICD-11 Code: XH36H6 |
NCT04843553
|
Acute kidney failure, stage unspecifiedDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GB60.Z |
NCT02701127
|
Macular degenerationDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9B75 |
NCT05062486
|
Sickle-cell disorderDisease Category: 03.Diseases of the blood or blood-forming organsDisease ICD-11 Code: 3A51 |
NCT04055818
|
Ductal carcinoma in situ of breastDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2E65.2 |
NCT01060345
|
Obstruction of bile ductDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DC10.02 |
NCT03418935
|
Hodgkin lymphomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B30 |
NCT00691210
|
Unspecified undernutritionDisease Category: 05.Endocrine, nutritional or metabolic diseasesDisease ICD-11 Code: 5B7Z |
NCT03268902
|
Basal cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C32 |
NCT03769285
|
Malignant lymphoma, not elsewhere classifiedDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B33.5 |
NCT00691210
|
Fragile X chromosomeDisease Category: 20.Developmental anomaliesDisease ICD-11 Code: LD55 |
NCT01855971
|
Depressive disorders, unspecifiedDisease Category: 06.Mental, behavioural or neurodevelopmental disordersDisease ICD-11 Code: 6A7Z |
NCT04670081
|
Malignant neoplasms of colonDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B90 |
NCT02891538
|
Hepatic fibrosis/cirrhosisDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DB93 |
NCT03278925
|
DNA repair defects other than combined T-cell or B-cell immunodeficienciesDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A01.31 |
NCT04870866
|
Unspecified malignant neoplasms of unspecified sitesDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2D4Z |
NCT04733534
|
Malignant neoplasms of other or unspecified parts of mouthDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B66 |
NCT05456022
|
Intracranial injury, unspecifiedDisease Category: 22.Injury, poisoning or certain other consequences of external causesDisease ICD-11 Code: NA07.Z |
NCT02731495
|
OsteoporosisDisease Category: 15.Diseases of the musculoskeletal system or connective tissueDisease ICD-11 Code: FB83.1 |
NCT00625391
|
LeukaemiaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2A60-2B33 |
NCT00262743
|
Squamous cell carcinomaDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B60-2D01 |
NCT03769285
|
Multiple system atrophyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8D87.0 |
NCT02008721
|
Human immunodeficiency virus disease without mention of associated disease or condition, clinical stage unspecifiedDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C62.Z |
NCT01433289
|
Malignant neoplasms of nasopharynxDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2B6B |
NCT01744587
|
Prostate hyperplasiaDisease Category: 16.Diseases of the genitourinary systemDisease ICD-11 Code: GA90 |
NCT00596011
|
Cystic fibrosisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA25 |
NCT01348204
|
Friedreich ataxiaDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A03.10 |
NCT03761511
|
Gastro-oesophageal reflux diseaseDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA22 |
NCT02226484
|
FrecklesDisease Category: 14.Diseases of the skinDisease ICD-11 Code: ED61.0 |
NCT03392623
|
Diabetic polyneuropathyDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8C03.0 |
NCT04649203
|
Relapsing-remitting multiple sclerosisDisease Category: 08.Diseases of the nervous systemDisease ICD-11 Code: 8A40.0 |
NCT00525668
|
Columnar metaplastic epithelium of the oesophagus, unspecifiedDisease Category: 13.Diseases of the digestive systemDisease ICD-11 Code: DA23.Z |
NCT00233935
|
Atrial fibrillationDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC81.3 |
CA7
|
KeratoconusDisease Category: 09.Diseases of the visual systemDisease ICD-11 Code: 9A78.50 |
CA4
|
Pneumonia due to PseudomonasaeruginosaDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA40.05 |
DPP4
|
Systemic sclerosisDisease Category: 04.Diseases of the immune systemDisease ICD-11 Code: 4A42 |
NOX4
|
Chronic rhinosinusitisDisease Category: 12.Diseases of the respiratory systemDisease ICD-11 Code: CA0A |
CYP1A1
|
Dilated cardiomyopathyDisease Category: 11.Diseases of the circulatory systemDisease ICD-11 Code: BC43.0 |
ABCG2
|
Lyme borreliosisDisease Category: 01.Certain infectious or parasitic diseasesDisease ICD-11 Code: 1C1G |
MET
|
❱❱❱ Network Visualization of Plant-Targeted Human Disease Associations
>> Targets derived from weak experimental activities
