CMAUP Plant Collective Molecular Activities

Collective Molecular Activities of the Plant: Scopolia Carniolica

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PLANiTS DNA barcode

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Taxonomic Information

Plant ID: NPO10384
Plant Latin Name: Scopolia Carniolica
Taxonomy Genus: Scopolia
Taxonomy Family: Solanaceae

Plant External Links:

NCBI TaxonomyDB: 258457
Plant-of-the-World-Online: n.a.

Used in Medicines

Country/Region:

China; South Korea; Croatia; Romania

Traditional Medicine System:

TCM

Medicinal Functions:

Antispasmodic; Hypnotic; Mydriatic; Narcotic

Geographical Distribution

Croatia; Romania; China; South Korea

Geographical Distribution

See the Plant Occurrence Worldwide with Latitude and Longitude Available

Compounds Summary

Overview of Ingredients

29 All known Ingredients in Total

Unique ingredients have been isolated from this plant.
Plant-Ingredients Associations were manually curated from publications or collected from other databases.

25 Ingredients with Acceptable Bioavailablity

Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:

SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
  ☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
  ☑ SIZE: 150g/mol < MW < 500g/mol
  ☑ POLAR(Polarity): 20Å² < TPSA < 130Å²
  ☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
  ☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
  ☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9

If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)