Plant ID: NPO10214
Plant Latin Name: Epimedium Wanshanense
Taxonomy Genus: Epimedium
Taxonomy Family: Berberidaceae
NCBI TaxonomyDB:
n.a.
Plant-of-the-World-Online:
n.a.
Ingredient ID: NPC77284
Ingredient ID: NPC280403
Ingredient ID: NPC273538
Ingredient ID: NPC23827
Ingredient ID: NPC191568
Ingredient ID: NPC145957
Clinical trials associated with plant from natural product (NP) & plant level:
Clinical trials type | Number of clinical trials | |
---|---|---|
NP level | 4 | |
NCT ID | Title | Condition | Form in clinical use | Associated by plant or compound |
---|---|---|---|---|
NCT03236649 | The Phase III Study of Icaritin Versus Sorafenib in PD-L1 Positive Advanced Hepatocellular Carcinoma Subjects | hepatocellular carcinoma | Icaritin (NPC273538) | NP level |
NCT02496949 | A Phase Ib Study to Assess Safety and Efficacy of Oral Icaritin in Advanced Solid Tumors | neoplasm | Icaritin (NPC273538) | NP level |
NCT01278810 | Phase I Study of Novel Estrogen Receptor(ER) a36 Modifier Icaritin in Advanced Breast Cancer Patients | breast cancer | Icaritin (NPC273538) | NP level |
NCT01972672 | The Phase II Study of Icaritin in Patients With Advanced Hepatocellular Carcinoma | hepatocellular carcinoma | Icaritin (NPC273538) | NP level |
How do we define the Plant-Targeted Human Disease Association?
Associated human diseases of an individual plant are summurized based on FOUR types of association evidence, these include:
❶ Association by Therapeutic Target: Bioactive protein targets of the plant were defined in "Molecular Targets" section, target-disease associations collected from TTD database were subsequently used to build the associations between the plant and its targeted human diseases.
❷ Association by Disease Gene Reversion: Plant and a specific disease will be associated when >= 1 plant target gene overlaped with disease's DEGs.
❸ Association by Clinical Trials of Plant: Plant and a specific disease will be associated when >= 1 clinical trial (the plant is the intervetion) can be matched in ClinicalTrials.gov database.
❹ Association by Clinical Trials of Plant Ingredients: Plant and a specific disease will be associated when >= 1 clinical trial (the plant ingredient is the intervetion) can be matched in ClinicalTrials.gov database.
Associated Disease of the Plant |
Association Type & Detailed Evidence |
---|---|
Hepatocellular carcinoma, NOSDisease Category: X.Extension CodesDisease ICD-11 Code: XH4W48 |
NCT01972672,NCT03236649
|
Breast cancerDisease Category: 02.NeoplasmsDisease ICD-11 Code: 2C60-2C6Y |
NCT01278810
|
NeoplasmsDisease Category: 02.NeoplasmsDisease ICD-11 Code: 02 |
NCT02496949
|