Collective Molecular Activities of the Plant: Nerium Oleander
Country/Region:
Thailand; Philippines; Indonesia; India; ChinaTraditional Medicine System:
Sowa-Rigpa; Indian Folk; Unani; Siddha; Ayurveda; TCM; HomeopathyMedicinal Functions:
Cancer; Cardiotonic; Diaphoretic; Diuretic; Emetic; Expectorant; Parasiticide; Resolvent; Skin; Sternutatory
Brazil; Afghanistan; Madagascar; Italy; Bangladesh; Nepal; Costa Rica; France; Ethiopia; Trinidad and Tobago; Cameroon; Australia; Iran; Algeria; El Salvador; Turkey; United States; Guatemala; Zimbabwe; China; Oman; Thailand; Belize; Spain; Eritrea; Libya; Iraq; Philippines; Indonesia; Portugal; Morocco; Kenya; New Zealand; Pakistan; Albania; Honduras; Myanmar; Chad; Mexico; Tunisia; Nicaragua; South Africa; India; Senegal; Greece; Japan; Niger; Cyprus
See the Plant Occurrence Worldwide with Latitude and Longitude Available
Overview of Ingredients
243 All known Ingredients in Total
Unique ingredients have been isolated from this plant.Plant-Ingredients Associations were manually curated from publications or collected from other databases.
110 Ingredients with Acceptable Bioavailablity
Unique ingredients exhibit acceptable human oral bioavailablity, according to the criteria of SwissADME [PMID: 28256516] and HobPre [PMID: 34991690]. The criteria details:SwissADME: six descriptors are used by SwissADME to evaluate the oral bioavailability of a natural product:
☑ LIPO(Lipophility): -0.7 < XLOGP3 < +5.0
☑ SIZE: 150g/mol < MW < 500g/mol
☑ POLAR(Polarity): 20Ų < TPSA < 130Ų
☑ INSOLU(Insolubility): -6 < Log S (ESOL) < 0
☑ INSATU(Insaturation): 0.25 < Fraction Csp3 < 1
☑ FLEX(Flexibility): 0 < Num. rotatable bonds < 9
If 6 descriptors of a natural plant satisfy the above rules, it will be labeled high HOB.
HobPre: A natural plant ingredient with HobPre score >0.5 is labeled high human oral availability (HOB)
87 Ingredients with experimental-derived Activity
Unique ingredients have activity data available.Ingredient Structrual Cards
Ingredient ID: NPC99080
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