Access Plants by Target KEGG Pathway (Enriched by target genes of the plant)

Pathway Category Top Level Pathway Category Second Level KEGG Pathway Name No. of Plants No. of Medicinal Plants No. of Food Plants No. of Human Edible Plants No. of Agricultural Plants No. of Garden Plants No. of Drug-producing Plants
Organismal Systems Endocrine system PPAR signaling pathway 513 293 126 162 1 17 128
Metabolism Lipid metabolism Arachidonic acid metabolism 930 449 165 285 1 28 226
Organismal Systems Endocrine system Ovarian steroidogenesis 2298 924 193 639 2 59 571
Organismal Systems Endocrine system Regulation of lipolysis in adipocytes 485 273 59 172 0 16 125
Organismal Systems Nervous system Serotonergic synapse 1058 525 189 318 0 29 249
Metabolism Amino acid metabolism Tryptophan metabolism 1951 806 174 559 1 47 477
Human Diseases Cancer: overview Central carbon metabolism in cancer 1862 785 181 528 1 49 431
Human Diseases Cancer: overview Proteoglycans in cancer 1805 780 179 507 0 48 433
Metabolism Xenobiotics biodegradation and metabolism Drug metabolism 1101 509 169 311 2 22 258
Environmental Information Processing Signal transduction MAPK signaling pathway 2012 830 186 569 1 50 473
Metabolism Lipid metabolism Steroid hormone biosynthesis 2089 855 199 599 2 51 504
Cellular Processes Cellular community - eukaryotes Adherens junction 1558 649 158 447 0 41 374
Human Diseases Cancer: specific types Melanoma 1514 647 157 432 0 39 358
Human Diseases Cancer: overview Pathways in cancer 1943 836 199 546 1 55 460
Metabolism Xenobiotics biodegradation and metabolism Metabolism of xenobiotics by cytochrome P450 2017 847 204 573 1 48 485
Human Diseases Cancer: overview Transcriptional misregulation in cancer 1668 706 164 477 1 44 409
Environmental Information Processing Signal transduction PI3K-Akt signaling pathway 1665 704 163 480 1 43 398
Metabolism Amino acid metabolism Phenylalanine metabolism 225 95 8 67 0 4 58
Metabolism Amino acid metabolism Histidine metabolism 182 78 6 53 0 4 51
Environmental Information Processing Signal transduction Ras signaling pathway 1688 709 168 492 0 43 404
Human Diseases Cancer: overview Chemical carcinogenesis 2362 981 225 676 3 57 574
Metabolism Lipid metabolism Linoleic acid metabolism 1052 469 168 302 1 24 247
Organismal Systems Endocrine system Thyroid hormone signaling pathway 470 254 87 145 1 18 114
Genetic Information Processing Replication and repair Base excision repair 647 276 82 192 0 16 146
Metabolism Amino acid metabolism Tyrosine metabolism 400 168 62 105 1 11 93
Cellular Processes Cell growth and death Apoptosis 963 481 177 288 1 31 235
Human Diseases Cancer: overview MicroRNAs in cancer 1649 713 178 467 1 49 394
Metabolism Amino acid metabolism Glycine, serine and threonine metabolism 130 55 4 41 0 3 36
Human Diseases Cancer: specific types Hepatocellular carcinoma 979 463 146 280 0 27 240
Human Diseases Substance dependence Cocaine addiction 822 388 112 234 0 16 211
Metabolism Amino acid metabolism Arginine and proline metabolism 132 55 4 41 0 4 34
Cellular Processes Cellular community - eukaryotes Focal adhesion 1495 618 134 426 0 37 356
Human Diseases Cancer: overview Viral carcinogenesis 1114 537 159 330 0 26 281
Environmental Information Processing Signal transduction Rap1 signaling pathway 1465 613 135 420 0 35 348
Human Diseases Cancer: specific types Acute myeloid leukemia 1669 715 184 471 1 44 381
Human Diseases Cardiovascular disease Lipid and atherosclerosis 1249 593 183 365 2 34 299
Cellular Processes Transport and catabolism Mitophagy 797 324 52 243 1 18 215
Metabolism Metabolism of cofactors and vitamins Retinol metabolism 1696 700 183 468 2 42 402
Human Diseases Substance dependence Amphetamine addiction 216 126 60 65 0 6 60
Human Diseases Cancer: specific types Renal cell carcinoma 609 307 110 173 0 11 155
Human Diseases Cancer: specific types Non-small cell lung cancer 670 336 117 190 0 14 163
Cellular Processes Cell growth and death p53 signaling pathway 122 67 14 41 0 5 33
Human Diseases Cancer: specific types Glioma 675 338 114 192 0 16 166
Human Diseases Neurodegenerative disease Parkinson disease 219 139 47 72 0 7 55
Metabolism Biosynthesis of other secondary metabolites Caffeine metabolism 1440 537 85 386 1 29 370
Human Diseases Cancer: specific types Prostate cancer 1326 627 199 381 1 33 320
Human Diseases Endocrine and metabolic disease AGE-RAGE signaling pathway in diabetic complications 1931 819 201 546 1 53 459
Organismal Systems Endocrine system Progesterone-mediated oocyte maturation 1063 480 132 290 0 31 240
Organismal Systems Aging Longevity regulating pathway 857 384 76 249 1 16 219
Environmental Information Processing Signal transduction HIF-1 signaling pathway 1749 733 190 490 1 37 432
Environmental Information Processing Signal transduction Sphingolipid signaling pathway 718 365 102 223 1 18 171
Cellular Processes Cell growth and death Cell cycle 130 62 9 44 0 4 30
Cellular Processes Cell growth and death Oocyte meiosis 622 281 89 166 0 17 145
Environmental Information Processing Signaling molecules and interaction Neuroactive ligand-receptor interaction 487 317 156 152 0 18 115
Organismal Systems Nervous system Dopaminergic synapse 222 113 40 71 0 7 57
Cellular Processes Transport and catabolism Autophagy 338 181 55 105 0 8 87
Metabolism Energy metabolism Nitrogen metabolism 2357 962 180 686 3 63 565
Organismal Systems Endocrine system Insulin signaling pathway 413 200 54 130 1 9 94
Human Diseases Substance dependence Alcoholism 148 93 32 48 0 2 38
Organismal Systems Excretory system Proximal tubule bicarbonate reclamation 931 394 92 280 1 22 233
Organismal Systems Endocrine system Relaxin signaling pathway 1005 503 157 311 1 27 235
Human Diseases Cancer: specific types Bladder cancer 825 427 141 258 0 28 215
Human Diseases Cancer: overview PD-L1 expression and PD-1 checkpoint pathway in cancer 1318 584 167 376 1 27 327
Organismal Systems Immune system IL-17 signaling pathway 614 351 139 187 0 22 156
Organismal Systems Immune system Th17 cell differentiation 1036 455 151 293 1 27 252
Environmental Information Processing Signal transduction cAMP signaling pathway 834 480 187 259 0 18 196
Organismal Systems Endocrine system Prolactin signaling pathway 1072 506 178 302 1 23 246
Human Diseases Cardiovascular disease Fluid shear stress and atherosclerosis 1136 534 171 323 1 28 284
Human Diseases Neurodegenerative disease Alzheimer disease 1131 559 185 337 0 29 267
Organismal Systems Immune system T cell receptor signaling pathway 611 273 82 165 0 12 137
Environmental Information Processing Signal transduction TNF signaling pathway 664 354 139 185 0 16 148
Human Diseases Cardiovascular disease Diabetic cardiomyopathy 689 350 100 218 0 19 174
Human Diseases Neurodegenerative disease Pathways of neurodegeneration 844 440 190 238 0 25 205
Human Diseases Infectious disease: viral Coronavirus disease 346 202 72 106 0 8 76
Organismal Systems Endocrine system Estrogen signaling pathway 994 494 172 274 1 29 229
Human Diseases Immune disease Inflammatory bowel disease 628 236 37 186 0 15 149
Organismal Systems Endocrine system Adipocytokine signaling pathway 345 172 58 105 1 7 70
Human Diseases Infectious disease: viral Hepatitis C 624 323 130 182 1 18 144
Human Diseases Infectious disease: viral Hepatitis B 817 411 135 238 1 28 194
Human Diseases Cancer: specific types Chronic myeloid leukemia 763 362 126 217 1 19 187
Human Diseases Cancer: specific types Pancreatic cancer 929 450 146 270 1 22 223
Human Diseases Infectious disease: bacterial Pertussis 332 181 81 98 0 6 84
Human Diseases Infectious disease: parasitic Leishmaniasis 353 190 82 103 0 8 82
Organismal Systems Immune system B cell receptor signaling pathway 472 229 83 131 0 7 105
Organismal Systems Digestive system Bile secretion 734 340 142 203 0 20 148
Organismal Systems Immune system Th1 and Th2 cell differentiation 282 144 56 77 0 6 63
Human Diseases Infectious disease: viral Kaposi sarcoma-associated herpesvirus infection 616 319 105 165 1 16 151
Human Diseases Infectious disease: bacterial Pathogenic Escherichia coli infection 203 99 30 55 0 6 51
Human Diseases Infectious disease: parasitic Chagas disease 434 220 84 119 0 7 91
Organismal Systems Immune system Toll-like receptor signaling pathway 465 231 86 129 0 8 99
Organismal Systems Immune system C-type lectin receptor signaling pathway 522 249 80 143 0 9 122
Environmental Information Processing Signal transduction NF-kappa B signaling pathway 505 202 37 148 0 11 134
Human Diseases Endocrine and metabolic disease Insulin resistance 500 221 48 148 1 10 113
Human Diseases Infectious disease: viral Human T-cell leukemia virus 1 infection 711 348 125 199 0 12 175
Human Diseases Infectious disease: parasitic Toxoplasmosis 434 210 74 125 0 9 104
Organismal Systems Nervous system Neurotrophin signaling pathway 556 277 88 162 1 13 123
Organismal Systems Development and regeneration Osteoclast differentiation 411 192 57 119 0 4 83
Human Diseases Infectious disease: bacterial Salmonella infection 361 165 45 104 0 9 84
Human Diseases Infectious disease: bacterial Yersinia infection 450 222 80 131 0 7 92
Human Diseases Endocrine and metabolic disease Type II diabetes mellitus 235 118 32 71 0 4 49
Human Diseases Infectious disease: viral Measles 766 319 60 221 1 14 188
Human Diseases Endocrine and metabolic disease Non-alcoholic fatty liver disease 318 147 28 100 1 4 74
Cellular Processes Cell growth and death Cellular senescence 791 374 126 224 1 20 194
Human Diseases Infectious disease: bacterial Legionellosis 342 145 35 109 0 7 89
Human Diseases Infectious disease: viral Influenza A 327 151 35 98 0 6 81
Organismal Systems Immune system Cytosolic DNA-sensing pathway 170 84 20 49 0 3 35
Organismal Systems Endocrine system GnRH secretion 265 153 63 86 0 5 55
Human Diseases Infectious disease: bacterial Tuberculosis 203 102 35 58 0 4 46
Organismal Systems Immune system NOD-like receptor signaling pathway 194 95 30 55 0 4 48
Human Diseases Infectious disease: viral Human papillomavirus infection 259 138 33 82 0 5 51
Human Diseases Infectious disease: bacterial Epithelial cell signaling in Helicobacter pylori infection 956 431 115 289 1 21 226
Organismal Systems Immune system RIG-I-like receptor signaling pathway 175 85 15 56 0 3 37
Organismal Systems Immune system Neutrophil extracellular trap formation 275 139 34 83 0 6 60
Organismal Systems Immune system Chemokine signaling pathway 253 121 28 75 0 4 63
Organismal Systems Endocrine system Thyroid hormone synthesis 67 46 6 31 0 3 29
Cellular Processes Transport and catabolism Endocytosis 320 120 18 96 0 5 84
Environmental Information Processing Signal transduction FoxO signaling pathway 593 274 115 161 0 11 131
Human Diseases Cancer: specific types Gastric cancer 634 295 77 193 0 16 144
Genetic Information Processing Replication and repair Fanconi anemia pathway 288 108 17 88 0 5 68
Environmental Information Processing Signal transduction VEGF signaling pathway 611 290 95 179 0 11 146
Environmental Information Processing Signal transduction Calcium signaling pathway 613 308 92 180 0 14 149
Human Diseases Infectious disease: bacterial Bacterial invasion of epithelial cells 336 128 13 86 0 3 87
Environmental Information Processing Signal transduction ErbB signaling pathway 455 222 60 123 1 10 92
Human Diseases Cancer: specific types Colorectal cancer 433 218 65 121 0 10 89
Cellular Processes Cellular community - eukaryotes Gap junction 725 377 157 216 0 20 173
Organismal Systems Endocrine system GnRH signaling pathway 381 207 80 108 1 11 82
Environmental Information Processing Signal transduction AMPK signaling pathway 241 100 6 64 0 1 56
Cellular Processes Cellular community - eukaryotes Signaling pathways regulating pluripotency of stem cells 285 134 32 71 0 3 65
Human Diseases Cancer: specific types Breast cancer 723 377 131 202 1 20 155
Environmental Information Processing Signal transduction Phospholipase D signaling pathway 314 178 115 76 0 8 56
Environmental Information Processing Signal transduction mTOR signaling pathway 248 111 16 62 0 3 65
Organismal Systems Endocrine system Oxytocin signaling pathway 138 61 10 35 0 3 46
Organismal Systems Immune system Hematopoietic cell lineage 248 83 7 62 0 7 65
Organismal Systems Immune system Leukocyte transendothelial migration 303 145 20 85 0 9 77
Organismal Systems Immune system Fc epsilon RI signaling pathway 216 111 27 59 0 3 34
Human Diseases Cancer: specific types Small cell lung cancer 534 238 49 143 1 14 123
Organismal Systems Sensory system Inflammatory mediator regulation of TRP channels 246 134 36 65 0 9 50
Organismal Systems Excretory system Aldosterone-regulated sodium reabsorption 220 107 23 61 0 3 47
Organismal Systems Digestive system Carbohydrate digestion and absorption 139 59 2 38 0 0 28
Human Diseases Infectious disease: viral Human cytomegalovirus infection 547 264 73 159 0 12 137
Human Diseases Cancer: specific types Endometrial cancer 251 154 63 75 0 5 45
Metabolism Carbohydrate metabolism Inositol phosphate metabolism 96 39 0 24 0 0 18
Organismal Systems Immune system Fc gamma R-mediated phagocytosis 199 87 11 61 0 4 43
Environmental Information Processing Signal transduction Phosphatidylinositol signaling system 95 40 0 26 0 1 20
Human Diseases Cancer: overview Choline metabolism in cancer 233 129 41 65 0 7 43
Human Diseases Infectious disease: parasitic Amoebiasis 320 140 9 89 0 5 79
Organismal Systems Nervous system Cholinergic synapse 343 163 38 99 0 8 68
Organismal Systems Endocrine system Growth hormone synthesis, secretion and action 167 75 9 45 0 3 37
Organismal Systems Immune system Platelet activation 195 83 13 46 0 2 48
Organismal Systems Immune system Natural killer cell mediated cytotoxicity 91 48 3 26 0 1 16
Human Diseases Neurodegenerative disease Spinocerebellar ataxia 172 67 1 45 0 2 37
Environmental Information Processing Signal transduction JAK-STAT signaling pathway 361 157 36 95 1 7 72
Organismal Systems Development and regeneration Axon guidance 173 77 5 45 0 1 40
Human Diseases Infectious disease: viral Epstein-Barr virus infection 284 122 12 77 0 3 58
Human Diseases Infectious disease: viral Human immunodeficiency virus 1 infection 486 230 62 144 0 10 108
Cellular Processes Cell motility Regulation of actin cytoskeleton 120 62 10 30 0 2 35
Organismal Systems Nervous system Long-term depression 268 180 131 75 0 10 67
Organismal Systems Nervous system Long-term potentiation 82 61 58 24 0 2 14
Human Diseases Endocrine and metabolic disease Cushing syndrome 44 33 16 16 0 1 4
Organismal Systems Endocrine system Melanogenesis 39 29 9 22 0 3 8
Human Diseases Infectious disease: bacterial Shigellosis 428 208 70 113 0 9 107
Human Diseases Cancer: specific types Thyroid cancer 136 95 42 41 0 4 40
Organismal Systems Circulatory system Vascular smooth muscle contraction 43 24 3 15 0 4 15
Human Diseases Neurodegenerative disease Prion disease 78 39 6 24 0 0 13
Cellular Processes Cell growth and death Ferroptosis 90 68 28 37 1 4 34
Genetic Information Processing Translation RNA transport 46 18 0 8 0 1 20
Metabolism Metabolism of cofactors and vitamins Folate biosynthesis 502 211 55 154 0 11 142
Organismal Systems Digestive system Gastric acid secretion 46 19 1 14 0 1 15
Metabolism Carbohydrate metabolism Galactose metabolism 165 71 11 59 0 4 58
Metabolism Carbohydrate metabolism Fructose and mannose metabolism 161 68 10 57 0 4 58
Metabolism Carbohydrate metabolism Pentose and glucuronate interconversions 165 71 11 59 0 4 58
Metabolism Lipid metabolism Glycerolipid metabolism 149 60 6 51 0 4 49
Human Diseases Immune disease Rheumatoid arthritis 4 4 1 2 0 0 1
Environmental Information Processing Signal transduction cGMP-PKG signaling pathway 154 95 38 49 0 6 38
Organismal Systems Nervous system Synaptic vesicle cycle 63 53 60 5 0 4 16
Metabolism Amino acid metabolism Valine, leucine and isoleucine degradation 106 72 41 28 0 3 16
Organismal Systems Sensory system Taste transduction 66 46 22 13 0 5 12
Organismal Systems Digestive system Salivary secretion 39 22 5 14 0 3 13
Organismal Systems Circulatory system Adrenergic signaling in cardiomyocytes 52 25 7 12 0 4 10
Organismal Systems Endocrine system Renin secretion 23 9 2 5 0 2 5
Human Diseases Substance dependence Morphine addiction 64 37 3 28 0 3 24
Metabolism Metabolism of cofactors and vitamins Thiamine metabolism 140 43 1 36 0 2 47
Organismal Systems Excretory system Collecting duct acid secretion 136 39 1 30 1 2 43
Organismal Systems Immune system Complement and coagulation cascades 90 32 2 31 0 3 21
Genetic Information Processing Replication and repair Homologous recombination 43 20 2 21 0 1 10
Human Diseases Neurodegenerative disease Huntington disease 11 7 4 2 0 0 3
Human Diseases Neurodegenerative disease Amyotrophic lateral sclerosis 49 17 2 12 0 1 13
Metabolism Metabolism of cofactors and vitamins Vitamin B6 metabolism 152 84 47 38 1 3 22
Human Diseases Infectious disease: parasitic Malaria 27 16 3 13 0 1 12
Genetic Information Processing Folding, sorting and degradation Protein processing in endoplasmic reticulum 32 5 0 3 0 0 15
Cellular Processes Cell growth and death Necroptosis 36 10 1 6 0 0 10
Organismal Systems Nervous system Glutamatergic synapse 151 119 127 31 0 9 25
Organismal Systems Nervous system Retrograde endocannabinoid signaling 121 89 86 25 0 4 15
Organismal Systems Digestive system Cholesterol metabolism 5 5 1 3 0 0 2
Metabolism Metabolism of other amino acids Glutathione metabolism 7 6 7 4 0 1 0
Organismal Systems Endocrine system Parathyroid hormone synthesis, secretion and action 42 30 12 20 0 1 4
Human Diseases Infectious disease: viral Herpes simplex virus 1 infection 44 18 0 15 0 1 11
Organismal Systems Endocrine system Insulin secretion 11 10 2 7 0 1 7
Brite Hierarchies Protein families: genetic information processing Proteasome 49 18 2 15 0 1 11
Organismal Systems Environmental adaptation Circadian rhythm 69 25 0 20 0 1 21
Human Diseases Immune disease Primary immunodeficiency 60 21 0 15 0 0 14
Organismal Systems Environmental adaptation Circadian entrainment 50 38 29 14 0 3 7
Metabolism Amino acid metabolism Arginine biosynthesis 6 4 1 3 0 1 1
Environmental Information Processing Signal transduction Apelin signaling pathway 10 6 1 5 0 2 2
Environmental Information Processing Signal transduction Wnt signaling pathway 41 18 2 12 0 1 13
Environmental Information Processing Signal transduction Hedgehog signaling pathway 9 2 0 2 0 0 1
Organismal Systems Endocrine system Aldosterone synthesis and secretion 14 7 0 8 0 1 6
Environmental Information Processing Membrane transport ABC transporters 13 2 0 6 0 0 4
Human Diseases Cancer: specific types Basal cell carcinoma 6 4 1 3 0 0 1
Metabolism Nucleotide metabolism Pyrimidine metabolism 12 8 3 6 0 1 1
Human Diseases Infectious disease: parasitic African trypanosomiasis 8 7 1 6 0 1 3
Metabolism Nucleotide metabolism Purine metabolism 9 7 1 5 0 0 3
Environmental Information Processing Signal transduction TGF-beta signaling pathway 6 6 3 5 0 0 0
Organismal Systems Excretory system Endocrine and other factor-regulated calcium reabsorption 9 7 0 6 0 1 4
Organismal Systems Nervous system GABAergic synapse 9 6 1 6 0 1 5
Organismal Systems Digestive system Pancreatic secretion 9 8 0 6 0 1 5
Organismal Systems Endocrine system Renin-angiotensin system 2 2 0 1 0 0 0
Human Diseases Cardiovascular disease Hypertrophic cardiomyopathy 4 4 0 3 0 0 0
Human Diseases Cardiovascular disease Dilated cardiomyopathy 4 4 0 3 0 0 0
Metabolism Metabolism of cofactors and vitamins Nicotinate and nicotinamide metabolism 1 0 0 0 0 0 0
Human Diseases Cardiovascular disease Arrhythmogenic right ventricular cardiomyopathy 2 2 0 2 0 0 0
Human Diseases Substance dependence Nicotine addiction 6 5 1 2 0 0 1
Cellular Processes Transport and catabolism Lysosome 3 2 1 1 0 0 0
Organismal Systems Immune system Antigen processing and presentation 1 1 0 1 0 0 0
Human Diseases Infectious disease: bacterial Vibrio cholerae infection 2 2 0 2 0 0 1
Organismal Systems Endocrine system Glucagon signaling pathway 4 0 0 3 0 0 1
Environmental Information Processing Signal transduction Notch signaling pathway 1 0 0 0 0 0 0
Metabolism Carbohydrate metabolism Pyruvate metabolism 5 4 1 2 0 1 0
Cellular Processes Cellular community - eukaryotes Tight junction 1 0 0 0 0 0 0
Metabolism Carbohydrate metabolism Starch and sucrose metabolism 4 3 1 2 0 0 0
Genetic Information Processing Transcription Basal transcription factors 1 0 0 0 0 0 0
Genetic Information Processing Replication and repair Nucleotide excision repair 1 0 0 0 0 0 0
Metabolism Metabolism of cofactors and vitamins One carbon pool by folate 1 0 0 0 0 0 0
Organismal Systems Endocrine system Cortisol synthesis and secretion 1 1 0 1 0 0 0
Organismal Systems Environmental adaptation Thermogenesis 2 1 0 2 0 0 0
Metabolism Metabolism of cofactors and vitamins Ubiquinone and other terpenoid-quinone biosynthesis 1 1 0 0 0 0 0
Metabolism Carbohydrate metabolism Ascorbate and aldarate metabolism 1 1 1 0 0 0 0
Metabolism Carbohydrate metabolism Glycolysis / Gluconeogenesis 1 1 0 0 0 0 0