Prescription Description
| Prescription ID | TCMFx3105 |
| Pinyin Name | Bai Bao Dan |
| Chinese Name | 百宝丹 |
| English Name | Bai Bao Dan |
| Function Description | 跌打损伤, 月经失调, 痛经, 闭经, 胃脘痛, 关节痛, 痹病 |
| Indications | Stomach ache disorder, Amenorrhea disorder, Dysmenorrhea disorder, Arthritis, Dysmenorrhea, Irregular menstruation |
| Disease ICD-11 Category |
SA51 [Stomach ache disorder (TM1), 胃脘痛 (TM1)
]; SB94 [Amenorrhea disorder (TM1), 闭经 (TM1) ]; SB96 [Dysmenorrhea disorder (TM1), 痛经 (TM1) ]; FA2Z [Inflammatory arthropathies, unspecified, 炎性关节病，未特指的 ]; GA34.3 [Dysmenorrhoea, 痛经 ]; GA20.3 [Abnormal regularity of uterine bleeding, 子宫出血周期异常 ]; |
| Human Tissues Associated with Indication | Uterus, SkeletalMuscle, Intestine, Stomach |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH1122 | Psammosilene tunicoides | 金铁锁 | TCMH1122 | ITSAQ267-14 |
| TCMH2646 | Rhizoma paridis | 重楼 | TCMH2646 | |
| TCMH222 | Aconitum carmichaelii | 草乌 | TCMH222 | ITSAH2410-14 |
| TCMH1768 | Panax notoginseng | 三七 | TCMH1768 | ITSAO2360-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT127 | PARP1 | Poly [ADP-ribose] polymerase-1 | Transferase | P09874 |
| TCMT128 | TNKS2 | Tankyrase-2 | Transferase | Q9H2K2 |
| TCMT129 | TNKS | Tankyrase-1 | Transferase | O95271 |
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT137 | CA9 | Carbonic anhydrase IX | Lyase | Q16790 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT156 | CYP19A1 | Cytochrome P450 19A1 | Oxidoreductase | P11511 |
| TCMT17 | POLB | DNA polymerase beta | Transferase | P06746 |
| TCMT289 | TBXAS1 | Thromboxane-A synthase | Isomerase | P24557 |
| TCMT614 | EGLN1 | Egl nine homolog 1 | Oxidoreductase | Q9GZT9 |
| TCMT636 | POLA1 | DNA polymerase alpha subunit | Transferase | P09884 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1170 | Enterobacter cloacae |
| TCMT1176 | Streptococcus pneumoniae |
| TCMT1218 | Staphylococcus aureus |
| TCMT1229 | Enterococcus faecalis |
| TCMT1232 | Pseudomonas aeruginosa |
| TCMT1243 | Aspergillus flavus |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1438 | Plasmodium falciparum |
| TCMT1454 | Bacillus subtilis |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples