TCM Prescription: Ma Ying Long She Xiang Zhi Chuang Ointment



Prescription Description
Prescription IDTCMFx298
Pinyin NameMa Ying Long She Xiang Zhi Chuang Gao 
Chinese Name马应龙麝香痔疮膏
English NameMa Ying Long She Xiang Zhi Chuang Ointment
Function Description痔疮, 肛裂
IndicationsFissured anus disorder, Hemorrhoids
Disease ICD-11 Category SB7C [Fissured anus disorder (TM1), 肛裂 (TM1) ];
DB60 [Haemorrhoids, 痔 ];
Human Tissues Associated with IndicationLarge Intestine
ReferenceChinese pharmacopoeia (2015)
Reference Book/linkISBN 978-7-5067-7337-9
Prescription Components
Component ID Latin Name Chinese Name Component Quantity Barcode
TCMH1717 Moschus moschiferus 人工麝香 TCMH1717 GBMA2112-09
TCMH1716 Calculus bovis artificiosus 人工牛黄 TCMH1716
TCMH2605 Margarita 珍珠 TCMH2605
TCMH1338 NA 炉甘石粉 TCMH1338
TCMH1613 Sal sedatirum 硼砂 TCMH1613
TCMH183 Dryobalanops aromatica 冰片 TCMH183 GBVK4926-11
TCMH916 Succinus 琥珀 TCMH916
Reference: Chinese pharmacopoeia (2015)

Targeted Human Proteins by the Ingredients of Prescription

Target ID Gene Symbol Target Name Target Class Uniprot ID
TCMT156 CYP19A1 Cytochrome P450 19A1 Oxidoreductase P11511
TCMT187 AR Androgen Receptor Nuclear receptor P10275
TCMT203 G6PD Glucose-6-phosphate 1-dehydrogenase Oxidoreductase P11413
TCMT230 HSD17B3 Estradiol 17-beta-dehydrogenase 3 Oxidoreductase P37058
TCMT236 ESR2 Estrogen receptor beta Nuclear receptor Q92731
TCMT261 DAPK1 Death-associated protein kinase 1 Kinase P53355
TCMT344 AOX1 Aldehyde oxidase Oxidoreductase Q06278
TCMT591 ESRRA Estrogen-related receptor alpha Nuclear receptor P11474
TCMT807 SLC22A12 Solute carrier family 22 member 12 Transporter Q96S37
TCMT82 ESR1 Estrogen receptor alpha Nuclear receptor P03372
TCMT907 FDPS Farnesyl diphosphate synthase Lyase P14324
TCMT910 ESRRB Estrogen-related receptor beta Nuclear receptor O95718
TCMT974 GPER1 G-protein coupled estrogen receptor 1 GPCR Q99527
TCMT99 SHBG Testis-specific androgen-binding protein Unclassified P04278


Targeted Pathogenic Microbes by the Ingredients of Prescription

Target ID Target Name
TCMT1181 Mycobacterium tuberculosis H37Ra
TCMT1229 Enterococcus faecalis
TCMT1232 Pseudomonas aeruginosa
TCMT1246 Escherichia coli
TCMT1251 Candida albicans
TCMT1255 Human immunodeficiency virus 1
TCMT1438 Plasmodium falciparum
TCMT1442 Leishmania donovani
TCMT1455 Mycobacterium tuberculosis H37Rv
TCMT1463 Mycobacterium tuberculosis
TCMT1465 Entamoeba histolytica

Gene Ontology Associated to Targeted Human Proteins

GO Term GO Name Enriched Genes Log10 Adjusted P-value


KEGG Pathways Associated to Targeted Human Proteins

KEGG Pathway ID Enriched Genes Log10 Adjusted P-value


Target Exprsssion in Healthy Human Tissues (protein & mRNA level)

Protein expression data was from the "Human Proteome Map" dataset
mRNA expression data was from the "GTEx" dataset



Average Target Expression (Fold Change) in Multiple Disease Conditions

Fold Change with Corresponding Normal Samples
Click each cell within the heatmap to access gene expression of individual patient samples
Data Section
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1. General Information of Prescription  
2. Putative Targets  
3. Activity & References for Filtering Putative Targets  
4. GO & Pathway