TCM Putative Target References: TCMFx298


Targeted Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.
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Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC903
TCMT175 G-protein coupled bile acid receptor 1 Homo sapiens IC50: 6000 (nM), Ref: 20801037
TCMC1112
TCMT203 Glucose-6-phosphate 1-dehydrogenase Homo sapiens Ki: 3400 (nM), Ref: 19231202
Ki: 3000 (nM), Ref: 19231202
IC50: 9400 (nM), Ref: 22506561
TCMC1155
TCMT230 Estradiol 17-beta-dehydrogenase 3 Homo sapiens IC50: 330 (nM), Ref: 11086723
IC50: 330 (nM), Ref: 16078844
TCMC1597
TCMT807 Solute carrier family 22 member 12 Homo sapiens IC50: 2000 (nM), Ref: 17325024
Ki: 5740 (nM), Ref: 17325024
TCMC1597
TCMT236 Estrogen receptor beta Homo sapiens IC50: 2927.18 (nM), Ref:
TCMC1597
TCMT61 Induced myeloid leukemia cell differentiation protein Mcl-1 Homo sapiens IC50: 2988.26 (nM), Ref:
TCMC1597
TCMT739 G-protein coupled receptor 35 Homo sapiens IC50: 1600 (nM), Ref: 24900447
TCMC1597
TCMT261 Death-associated protein kinase 1 Homo sapiens IC50: 1600 (nM), Ref: 26322379
TCMC1597
TCMT283 Receptor-type tyrosine-protein phosphatase S Homo sapiens IC50: 4300 (nM), Ref: 26602279
TCMC1898
TCMT215 Cytochrome P450 1A1 Homo sapiens IC50: 7906 (nM), Ref: 20696580
TCMC1898
TCMT257 Cytochrome P450 1B1 Homo sapiens IC50: 1679 (nM), Ref: 20696580
TCMC1898
TCMT219 Cytochrome P450 1A2 Homo sapiens IC50: 1491 (nM), Ref: 20696580
TCMC1898
TCMT156 Cytochrome P450 19A1 Homo sapiens IC50: 900 (nM), Ref: 10.1039/C3MD00166K
TCMC732
TCMT280 Aldo-keto reductase family 1 member B10 Homo sapiens IC50: 5900 (nM), Ref: 21561086
TCMC2018
TCMT907 Farnesyl diphosphate synthase Homo sapiens IC50: 452.9 (nM), Ref: 18327899
Ki: 82.2 (nM), Ref: 18327899
IC50: 5.7 (nM), Ref: 18327899
Ki: 0.36 (nM), Ref: 18327899
IC50: 5.7 (nM), Ref: 18434151
IC50: 300 (nM), Ref: 20801032
IC50: 11 (nM), Ref: 22390415
IC50: 860 (nM), Ref: 22390415
IC50: 11 (nM), Ref: 22884353
IC50: 10 (nM), Ref: 21780776
IC50: 5.2 (nM), Ref: 23998921
IC50: 11 (nM), Ref: 23998921
IC50: 6 (nM), Ref: 24911527
IC50: 11 (nM), Ref: 25630225
IC50: 6 (nM), Ref: 25935643
IC50: 0.36 (nM), Ref: 25815158
IC50: 82 (nM), Ref: 25815158
TCMC1133
TCMT82 Estrogen receptor alpha Homo sapiens IC50: 1.3 (nM), Ref: 15203155
IC50: 3 (nM), Ref: 10673099
IC50: 1.3 (nM), Ref: 15203156
Ki: 100 (nM), Ref: 12954056
IC50: 2 (nM), Ref: 12749898
IC50: 5.9 (nM), Ref: 10447957
IC50: 1.3 (nM), Ref: 15745820
IC50: 1.3 (nM), Ref: 15664843
IC50: 1.3 (nM), Ref: 15582421
IC50: 1.3 (nM), Ref: 15225685
IC50: 1.3 (nM), Ref: 15225686
IC50: 3.2 (nM), Ref: 15341953
IC50: 3.2 (nM), Ref: 15456246
IC50: 3.2 (nM), Ref: 15876535
IC50: 3.2 (nM), Ref: 15943471
IC50: 28 (nM), Ref: 15658851
Ki: 1.995 (nM), Ref: 15771467
IC50: 3.2 (nM), Ref: 16098741
IC50: 0.75 (nM), Ref: 16219463
IC50: 1.4 (nM), Ref: 16309907
IC50: 1.35 (nM), Ref: 16412638
IC50: 10 (nM), Ref: 16610787
IC50: 1.3 (nM), Ref: 16632357
IC50: 1.3 (nM), Ref: 16730987
IC50: 46 (nM), Ref: 16942012
IC50: 1.6 (nM), Ref: 16942012
IC50: 1.3 (nM), Ref: 16777408
IC50: 1.2 (nM), Ref: 17149865
IC50: 4.7 (nM), Ref: 17696335
IC50: 3.6 (nM), Ref: 17049855
IC50: 3.2 (nM), Ref: 17188490
IC50: 1 (nM), Ref: 17289385
IC50: 1.4 (nM), Ref: 17448656
IC50: 1.4 (nM), Ref: 17890084
IC50: 4 (nM), Ref: 18760603
Ki: 2 (nM), Ref: 18722117
IC50: 12.5 (nM), Ref: 19836949
IC50: 3.2 (nM), Ref: 19705860
Ki: 0.16 (nM), Ref: 20621492
IC50: 21.04 (nM), Ref: 20812681
IC50: 46 (nM), Ref: 20875743
IC50: 1.3 (nM), Ref: 24315190
IC50: 5.7 (nM), Ref: 25369367
IC50: 0.9 (nM), Ref: 26183544
Ki: 0.21 (nM), Ref: Ki: 0.21 (nM), Ref: IC50: 1.7 (nM), Ref: 27407030
TCMC1133
TCMT236 Estrogen receptor beta Homo sapiens IC50: 1.1 (nM), Ref: 15203155
IC50: 4 (nM), Ref: 10673099
IC50: 1.1 (nM), Ref: 15203156
Ki: 100 (nM), Ref: 12954056
IC50: 2 (nM), Ref: 12749898
IC50: 1.1 (nM), Ref: 15745820
IC50: 1.1 (nM), Ref: 15664843
IC50: 1.1 (nM), Ref: 15993065
IC50: 1.1 (nM), Ref: 15582421
IC50: 1.1 (nM), Ref: 15225685
IC50: 1.1 (nM), Ref: 15225686
IC50: 3.6 (nM), Ref: 15341953
IC50: 3.6 (nM), Ref: 15456246
IC50: 3.6 (nM), Ref: 15876535
IC50: 3.6 (nM), Ref: 15943471
IC50: 24 (nM), Ref: 15658851
Ki: 3.162 (nM), Ref: 15771467
IC50: 3.6 (nM), Ref: 16098741
IC50: 1.18 (nM), Ref: 16219463
IC50: 1.2 (nM), Ref: 16309907
IC50: 1.2 (nM), Ref: 16412638
IC50: 11 (nM), Ref: 16610787
IC50: 1.2 (nM), Ref: 16632357
IC50: 1.2 (nM), Ref: 16730987
IC50: 1.4 (nM), Ref: 16942012
IC50: 1.1 (nM), Ref: 16777408
IC50: 1.4 (nM), Ref: 17149865
IC50: 16.7 (nM), Ref: 17696335
IC50: 3.2 (nM), Ref: 17049855
IC50: 3.6 (nM), Ref: 17188490
IC50: 1 (nM), Ref: 17289385
IC50: 1.2 (nM), Ref: 17448656
IC50: 1.2 (nM), Ref: 17890084
IC50: 4 (nM), Ref: 18760603
Ki: 2 (nM), Ref: 18722117
IC50: 2.9 (nM), Ref: 19705860
IC50: 10.74 (nM), Ref: 20812681
IC50: 0.046 (nM), Ref: 24315190
IC50: 5.6 (nM), Ref: 25369367
Ki: 0.015 (nM), Ref: Ki: 0.015 (nM), Ref: IC50: 3 (nM), Ref: 27407030
TCMC1133
TCMT187 Androgen Receptor Homo sapiens IC50: 19.1 (nM), Ref: 16309907
TCMC1133
TCMT99 Testis-specific androgen-binding protein Homo sapiens IC50: 50 (nM), Ref: 17149875
TCMC1133
TCMT591 Estrogen-related receptor alpha Homo sapiens IC50: 3.6 (nM), Ref: 17482813
IC50: 6 (nM), Ref: 23448346
TCMC1133
TCMT910 Estrogen-related receptor beta Homo sapiens IC50: 3.2 (nM), Ref: 17482813
IC50: 8.7 (nM), Ref: 23448346
TCMC1133
TCMT344 Aldehyde oxidase Homo sapiens IC50: 80 (nM), Ref: 20853847
Ki: 4400 (nM), Ref: 22996261
Ki: 870 (nM), Ref: 22996261
TCMC1133
TCMT974 G-protein coupled estrogen receptor 1 Homo sapiens Ki: 5.7 (nM), Ref: 23672690
Ki: 2.7 (nM), Ref: 10.1039/C5MD00455A

Targeted Pathogenic Microbes or non-Human Proteins by the Ingredients of Prescription

References are linked to referred publications via PubMed ID or DOI.
There may be multiple activity records for a specific ingredient-target pair.

Ingredient ID & Structure Target ID Target Name Target Organism Activity Records & Reference
TCMC2264
TCMT1136 Neuraminidase H1N1 swine influenza virus IC50: 13.01 (ug/ml), Ref: 22552195
IC50: 11.54 (ug/ml), Ref: 22552195
IC50: 22.45 (ug/ml), Ref: 22552195
IC50: 23.54 (ug/ml), Ref: 22552195
TCMC2264
TCMT1136 Neuraminidase Influenza A virus IC50: 13.01 (ug/ml), Ref: 22552195
IC50: 11.54 (ug/ml), Ref: 22552195
IC50: 22.45 (ug/ml), Ref: 22552195
IC50: 23.54 (ug/ml), Ref: 22552195
TCMC903
TCMT1251 Candida albicans Candida albicans MIC: 64 (ug/ml), Ref: 18805690
TCMC903
TCMT1246 Escherichia coli Escherichia coli MIC: 64 (ug/ml), Ref: 18805690
MIC: 7.81 (ug/ml), Ref: 20181416
MIC: 4 (ug/ml), Ref: 20038628
MIC: 8 (ug/ml), Ref: 20038628
MIC: 16 (ug/ml), Ref: 20038628
TCMC903
TCMT1232 Pseudomonas aeruginosa Pseudomonas aeruginosa MIC: 15.63 (ug/ml), Ref: 20181416
TCMC903
TCMT1229 Enterococcus faecalis Enterococcus faecalis MIC: 31.25 (ug/ml), Ref: 20181416
TCMC1898
TCMT1181 Mycobacterium tuberculosis H37Ra Mycobacterium tuberculosis H37Ra MIC: 12.5 (ug/ml), Ref: 22280816
TCMC1898
TCMT1465 Entamoeba histolytica Entamoeba histolytica IC50: 80.76 (ug/ml), Ref: 10.1007/s00044-011-9767-1
TCMC1898
TCMT1455 Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC: 73 (ug/ml), Ref: 10.1007/s00044-013-0485-8
MIC: 63.3 (ug/ml), Ref: 10.1007/s00044-013-0485-8
TCMC732
TCMT1255 Human immunodeficiency virus 1 Human immunodeficiency virus 1 IC50: 9 (ug/ml), Ref: 9748372
TCMC2822
TCMT1463 Mycobacterium tuberculosis Mycobacterium tuberculosis MIC: 6.25 (ug/ml), Ref: 17845001
TCMC2018
TCMT1155 Farnesyl pyrophosphate synthase Leishmania major Ki: 17 (nM), Ref: 15828834