TCM-ID Component

Description of the Component

Component ID	TCMH2745
Latin Name	Stephania hernandifolia
English Name	NA
Chinese Pinyin Name	Zuan Di Feng
中文名	钻地风
TCM Properties
TCM Meridians
Therapeutic Class English
Therapeutic Class Chinese
Functions
Toxicity	NA
Geo-authentic habitats (道地产区)	NA
Reference	Chinese Pharmacopoeia (2015)
Barcode ID
Barcode Source

TCM Prescriptions with the Component

Prescription ID	Prescription English Name	Prescription Chinese Name
TCMFx2937	A Wei She Xiang Hua Ji Ointment	阿魏麝香化积膏
TCMFx819	Heng Gu Gu Shang Yu Recipe	恒古骨伤愈合剂
TCMFx5029	Qian Zi Hong Capsules	千紫红胶囊
TCMFx5038	Qian Zi Hong Granules	千紫红颗粒
TCMFx5293	Wai Yong Wu Di Ointment	外用无敌膏
TCMF5586	Wei Chang Ling Capsules	胃肠灵胶囊
TCMF6677	Zhi Xie Li Granules	止泻利颗粒

Targeted Human Proteins by the Ingredient of Component

Target ID	Gene Symbol	Target Name	Target Class	Uniprot ID
TCMT113	OPRD1	Delta opioid receptor	GPCR	P41143
TCMT133	CA1	Carbonic anhydrase I	Lyase	P00915
TCMT134	CA2	Carbonic anhydrase II	Lyase	P00918
TCMT135	CA14	Carbonic anhydrase XIV	Lyase	Q9ULX7
TCMT136	CA12	Carbonic anhydrase XII	Lyase	O43570
TCMT137	CA9	Carbonic anhydrase IX	Lyase	Q16790
TCMT138	CA7	Carbonic anhydrase VII	Lyase	P43166
TCMT139	CA6	Carbonic anhydrase VI	Lyase	P23280
TCMT140	CA5B	Carbonic anhydrase VB	Lyase	Q9Y2D0
TCMT141	CA5A	Carbonic anhydrase VA	Lyase	P35218
TCMT142	CA4	Carbonic anhydrase IV	Lyase	P22748
TCMT143	CA3	Carbonic anhydrase III	Lyase	P07451
TCMT159	TYR	Tyrosinase	Oxidoreductase	P14679
TCMT207	BACE1	Beta-secretase 1	Protease	P56817
TCMT223	AKR1B1	Aldose reductase	Oxidoreductase	P15121
TCMT337	XPO1	Exportin-1	Unclassified	O14980
TCMT599	UBE2N	Ubiquitin-conjugating enzyme E2 N	Transferase	P61088
TCMT8	KDM4E	Lysine-specific demethylase 4D-like	Oxidoreductase	B2RXH2

Targeted Pathogenic Microbes by the Ingredient of Component

Target ID	Target Name
TCMT1438	Plasmodium falciparum
TCMT1465	Entamoeba histolytica

Ingredient Structrues

Ingredient ID: TCMC717
Formula: C12H16O7

Common Name	Arbutin
IUPAC Name	(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
Canonical SMILES	OC[C@H]1O[C@@H](Oc2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O
Standard InCHI	InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12-/m1/s1
Standard InCHIKey	BJRNKVDFDLYUGJ-RMPHRYRLSA-N
External Identifiers	ChEMBL [CHEMBL232202]; PubChem [440936];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1186	Lycium chinense	Gou Qi Zi	枸杞子
TCMH1601	Nelumbo nucifera	Ou Pian	藕片
TCMH1197	Selaginella tamariscina	Juan Bai	卷柏
TCMH1889	Lycopodium japonicum	Shen Jin Cao	伸筋草
TCMH2285	Asparagus officinalis	Xiao Bai Bu	小百部
TCMH1383	Onobrychis viciifolia	Lv Dou	绿豆
TCMH2745	Stephania hernandifolia	Zuan Di Feng	钻地风
TCMH1437	Rhododendron dauricum	Man Shan Hong	满山红
TCMH1185	Lycium chinense	Gou Qi	枸杞
TCMH814	Nelumbo nucifera	He Geng	荷梗
TCMH825	Nelumbo nucifera	He Ye	荷叶
TCMH1275	Nelumbo nucifera	Lian Zi	莲子
TCMH1276	Nelumbo nucifera	Lian Zi Xin	莲子心
TCMH1598	Nelumbo nucifera	Ou	藕
TCMH1599	Nelumbo nucifera	Ou Fen	藕粉
TCMH1928	Asparagus officinalis	Shi Diao Bai	石刁柏

Ingredient ID: TCMC644
Formula: C20H25NO5

Common Name	Aknadinine
IUPAC Name	n.a.
Canonical SMILES	COC1=C(OC)[C@@]23[C@](CC1=O)(CCN3C)c1c(CC2)ccc(c1O)OC
Standard InCHI	InChI=1S/C20H25NO5/c1-21-10-9-19-11-13(22)17(25-3)18(26-4)20(19,21)8-7-12-5-6-14(24-2)16(23)15(12)19/h5-6,23H,7-11H2,1-4H3/t19-,20+/m0/s1
Standard InCHIKey	XLWYWPDYNLZUJS-VQTJNVASSA-N
External Identifiers	ChEMBL [CHEMBL1098359]; PubChem [159966];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2745	Stephania hernandifolia	Zuan Di Feng	钻地风

Ingredient ID: TCMC2373
Formula: C36H38N2O6

Common Name	Isochondodendrine
IUPAC Name	n.a.
Canonical SMILES	COc1cc2CCN([C@H]3c2c(c1O)Oc1ccc(cc1)C[C@H]1N(C)CCc2c1c(Oc1ccc(C3)cc1)c(O)c(c2)OC)C
Standard InCHI	InChI=1S/C36H38N2O6/c1-37-15-13-23-19-29(41-3)33(39)35-31(23)27(37)17-21-5-9-26(10-6-21)44-36-32-24(20-30(42-4)34(36)40)14-16-38(2)28(32)18-22-7-11-25(43-35)12-8-22/h5-12,19-20,27-28,39-40H,13-18H2,1-4H3/t27-,28-/m1/s1
Standard InCHIKey	XIOGHHPVBVXQIV-VSGBNLITSA-N
External Identifiers	ChEMBL [CHEMBL1169628]; PubChem [197726];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2745	Stephania hernandifolia	Zuan Di Feng	钻地风

Ingredient ID: TCMC1669
Formula: C36H36N2O5

Common Name	n.a.
IUPAC Name	n.a.
Canonical SMILES	COc1ccc2cc1Oc1ccc(cc1)C[C@@H]1N(C)CCc3c1c1Oc4c5[C@H](C2)N(C)CCc5ccc4Oc1c(c3)OC
Standard InCHI	InChI=1S/C36H36N2O5/c1-37-15-13-23-8-12-29-34-32(23)27(37)18-22-7-11-28(39-3)30(19-22)41-25-9-5-21(6-10-25)17-26-33-24(14-16-38(26)2)20-31(40-4)35(42-29)36(33)43-34/h5-12,19-20,26-27H,13-18H2,1-4H3/t26-,27-/m0/s1
Standard InCHIKey	IGGMWDYWFSLMOW-SVBPBHIXSA-N
External Identifiers	ChEMBL [CHEMBL503363]; PubChem [44143978];
Reference of Component-Ingredient Pair	N/A

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH1516	Cocculus trilobus	Mu Fang Ji	木防己
TCMH2745	Stephania hernandifolia	Zuan Di Feng	钻地风
TCMH2135	Glycyrrhiza uralensis	Tu Gan Cao	土甘草
TCMH628	Glycyrrhiza uralensis	Gan Cao	甘草
TCMH629	Glycyrrhiza uralensis	Gan Cao Fen	甘草粉
TCMH630	Glycyrrhiza uralensis	Gan Cao Gan Gao	甘草干膏
TCMH631	Glycyrrhiza uralensis	Gan Cao Gan Gao Fen	甘草干膏粉
TCMH632	Glycyrrhiza uralensis	Gan Cao Gan Jin Gao	甘草干浸膏
TCMH633	Glycyrrhiza uralensis	Gan Cao Gao	甘草膏
TCMH634	Glycyrrhiza uralensis	Gan Cao Jie	甘草节
TCMH635	Glycyrrhiza uralensis	Gan Cao Jin Gao	甘草浸膏
TCMH636	Glycyrrhiza uralensis	Gan Cao Liu Jin Gao	甘草流浸膏
TCMH1475	Glycyrrhiza uralensis	Mi Gan Cao	蜜甘草
TCMH1899	Glycyrrhiza uralensis	Sheng Gan Cao	生甘草

Ingredient ID: TCMC1319
Formula: C10H8O3

Common Name	Herniarin
IUPAC Name	7-methoxychromen-2-one
Canonical SMILES	COc1ccc2c(c1)oc(=O)cc2
Standard InCHI	InChI=1S/C10H8O3/c1-12-8-4-2-7-3-5-10(11)13-9(7)6-8/h2-6H,1H3
Standard InCHIKey	LIIALPBMIOVAHH-UHFFFAOYSA-N
External Identifiers	ChEMBL [CHEMBL49732]; PubChem [10748];
Reference of Component-Ingredient Pair	22860452

Occurrence of the ingredient across TCM components

Component ID	Latin Name	Pinyin Name	Chinese Name
TCMH2495	Artemisia capillaris	Yin Chen Hao Gan Jin Gao	茵陈蒿干浸膏
TCMH2562	Ruta graveolens	Yun Xiang Jin Gao	芸香浸膏
TCMH2362	Artemisia lactiflora	Ya Jiao Ai	鸭脚艾
TCMH2745	Stephania hernandifolia	Zuan Di Feng	钻地风
TCMH2035	Pinus massoniana	Song Zhi	松脂
TCMH1846	Artemisia capillaris	Shan Yin Chen	山茵陈
TCMH2154	Artemisia capillaris	Tu Yin Chen Hao	土茵陈蒿
TCMH2494	Artemisia capillaris	Yin Chen Hao	茵陈蒿
TCMH1417	Pinus massoniana	Ma Wei Song Gen	马尾松根
TCMH1418	Pinus massoniana	Ma Wei Song Shu Gen	马尾松树根
TCMH2033	Pinus massoniana	Song Xiang	松香
TCMH1782	Ruta graveolens	San Ya Ku	三桠苦
TCMH2017	Artemisia lactiflora	Si Ji Cai	四季菜

Properties

Ingredient ID	Formulae	Name	MW	AlogP	MlogP	XlogP	# HBA	# HBD	PSA	# Rotatable Bond	# Ring	# Heacy Atom	Lipinski RO5 Violation
TCMC644	C20H25NO5	Aknadinine	359.17	-1.2245	3	1.284	4	1	68.23	8	4	26	0
TCMC717	C12H16O7	Arbutin	272.09	-2.6675	2.01	-0.238	5	5	119.61	8	2	19	0
TCMC1319	C10H8O3	Herniarin	176.05	0.2182	2.23	2.051	1	0	35.53	2	2	13	0
TCMC1669	C36H36N2O5		576.26	0.2235	4.65	6.078	2	0	52.63	6	7	43	1
TCMC2373	C36H38N2O6	Isochondodendrine	594.27	-0.543	4.54	5.06	2	2	83.86	8	6	44	1

Download Data

All data can be downloaded by:

→ Selecting data type in the below download table
→ Then click the download button.

Data Section	Select to Download
1. General Information of the Component
2. TCM Prescriptions with the Component
3. Putative Targets
4. Activity & References for Filtering Putative Targets
5. Ingredient Data & Chemical Structure Information (Properties, InChI, InChIkey, SMILES, etc.)

Component: Stephania hernandifolia 钻地风

Description of the Component

Component ID

Latin Name

English Name

Chinese Pinyin Name

中文名

TCM Properties

TCM Meridians

Therapeutic Class English

Therapeutic Class Chinese

Functions

Toxicity

Geo-authentic habitats (道地产区)

Reference

Barcode ID

Barcode Source

TCM Prescriptions with the Component

Targeted Human Proteins by the Ingredient of Component

Targeted Pathogenic Microbes by the Ingredient of Component

Ingredient Structrues

Ingredient ID: TCMC717

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC644

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC2373

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1669

Occurrence of the ingredient across TCM components

Ingredient ID: TCMC1319

Occurrence of the ingredient across TCM components

Properties

Download Data