Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC234536 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC234536 POLB 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243509 BACE1 2 Median: 61150
Range: 30500 to 91800
IC50 PMID: 19939683
PMID: 22222157
NPC243509 GAA 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC243509 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243509 ABCB1 1 28000 IC50 DOI: 10.1039/C4MD00196F
NPC257188 MAPT 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC257188 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 CA12 1 25700 Ki PMID: 22892213
NPC257188 CA1 1 21500 Ki PMID: 22892213
NPC257188 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC33320 TSHR 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 GLA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 GAA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 RECQL 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA13 1 17800 Ki PMID: 22892213
NPC33320 CYP3A4 4 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA1 1 10560 Ki PMID: 22892213