Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC107482 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC113733 POLB 2 Median: 51840
Range: 43400 to 60280
IC50 PMID: 14640519
PMID: 18343122
NPC13768 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13768 CYP2D6 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC13768 MAPT 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC144682 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 ABAT 1 17100 IC50 PMID: 16290145
NPC203719 ALDH5A1 1 15600 IC50 PMID: 16290145
NPC203719 ALDH1A1 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC294941 ALOX15 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 KDM4E 3 Median: 35481.3
Range: 28183.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294941 MAPK1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 ALDH1A1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294941 HPGD 2 Median: 21169.9
Range: 19952.6 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC13768 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC13768 CYP2C9 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862