Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC204932 CA14 2 Median: 48900
Range: 48900 to 48900
Ki PMID: 18579385
PMID: 20185318
NPC204932 BLM 2 Median: 44668.4
Range: 44668.4 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 POLB 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 APEX1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 EGFR 1 26043 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC204932 MMP9 1 23367 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC204932 TDP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 L3MBTL1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 FYN 1 17431 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC204932 RECQL 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 ALOX15 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC286006 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 GLA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 GAA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 RECQL 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA13 1 17800 Ki PMID: 22892213
NPC87125 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC87125 TDP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 KDM4E 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 ALDH1A1 2 Median: 15954.1
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 CA3 2 Median: 13000
Range: 13000 to 13000
Ki PMID: 18579385
PMID: 20185318
NPC204932 SMN1;SMN2 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 LMNA 2 Median: 23350.75
Range: 11220.2 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 HPGD 2 Median: 14501.5
Range: 11220.2 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC204932 GMNN 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC204932 CA4 3 Median: 10900
Range: 10900 to 10900
Ki PMID: 18579385
PMID: 20185318
PMID: 22245047
NPC294852 CYP1A1 1 10973 IC50 PMID: 20696580
NPC76336 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA1 1 10560 Ki PMID: 22892213
NPC87125 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862