Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC136330 | CTSD | 1 | 42300 | IC50 |
DOI: 10.1007/s00044-012-0397-z |
| NPC136330 | MAPK1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC136330 | HSD17B10 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC136330 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC136330 | KDM4E | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC136330 | HPGD | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC136330 | ABCB1 | 2 |
Median: 44800 Range: 15500 to 74100 |
IC50 |
PMID: 12130727 PMID: 12130727 |
| NPC136330 | SMN1;SMN2 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | ALOX15 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | PPARG | 1 | 30000 | IC50 |
DOI: 10.1007/s00044-012-0285-6 |
| NPC209970 | TDP1 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC209970 | HSD17B10 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC230301 | DPP4 | 1 | 28840 | IC50 |
DOI: 10.1039/C0MD00245C |
| NPC230301 | POLB | 1 | 26300 | IC50 |
PMID: 14640519 |
| NPC257124 | AR | 2 |
Median: 19027.305 Range: 19000 to 19054.61 |
IC50 |
PMID: 20226658 PMID: 20226658 |
| NPC292792 | PPARA | 1 | 46500 | EC50 |
PMID: 22381047 |
| NPC292792 | PPARG | 1 | 40000 | EC50 |
PMID: 22381047 |
| NPC292792 | ALDH1A1 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC136330 | CYP3A4 | 2 |
Median: 12589.3 Range: 12589.3 to 12589.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | ALDH1A1 | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC257124 | PTGS1 | 1 | 11000 | IC50 |
PMID: 16038536 |