Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC176740 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC176740 EPHX2 1 24300 IC50 PMID: 24679441
NPC176740 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC247553 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 GAA 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 AKR1B1 1 22900 IC50 PMID: 20805028
NPC247553 CASP1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 CASP7 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC247553 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 GLA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 MAPT 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 LMNA 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC281131 EPHX2 1 21760 IC50 PMID: 24679441
NPC51700 PPARA 1 41310 EC50 PMID: 21855333
NPC51700 AKR1B1 1 41000 IC50 PMID: 21561086
NPC51700 CYP19A1 1 32000 IC50 PMID: 18192087
NPC51700 PTPN6 1 25780 IC50 PMID: 18707891
NPC51700 POLB 1 18600 IC50 PMID: 15165161
NPC51700 CTSD 1 18200 IC50 DOI: 10.1007/s00044-012-0397-z
NPC51700 SLCO1B1 1 15848.93 IC50 PMID: 23571415
NPC51700 SLCO1B3 1 11481.54 IC50 PMID: 23571415