Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC120840 PTPN1 1 21500 IC50 PMID: 25264584
NPC142415 ACP1 4 Median: 22050
Range: 21200 to 22900
IC50 PMID: 21453996
PMID: 21453996
PMID: 25264584
PMID: 25264584
NPC142415 PTPN6 2 Median: 22760
Range: 14190 to 31330
IC50 PMID: 18707891
PMID: 27123900
NPC148757 ABCG2 1 22600 IC50 PMID: 21275386
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC264317 POLB 2 Median: 44925
Range: 43600 to 46250
IC50 PMID: 14640519
PMID: 18343122
NPC264317 GLI1 2 Median: 32000
Range: 32000 to 32000
IC50 PMID: 18842418
PMID: 19309080
NPC37496 CYP2D6 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC142415 PTPRF 2 Median: 17055
Range: 11800 to 22310
IC50 PMID: 21453996
PMID: 27123900
NPC142415 PTPN11 1 11620 IC50 PMID: 27123900
NPC192638 TOP2A 1 10400 IC50 PMID: 11754608
NPC264317 AKR1B1 1 11000 IC50 PMID: 21561086
NPC37496 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862