Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC200740 DPP4 1 41690 IC50 DOI: 10.1039/C0MD00245C
NPC225710 SELL 1 27600 IC50 PMID: 17302397
NPC225710 GAPDH 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 MAPK1 2 Median: 23753.05
Range: 22387.2 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC225710 SELP 1 19100 IC50 PMID: 17302397
NPC225710 SMN1;SMN2 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC274721 MAPT 2 Median: 37646
Range: 35481.3 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC274721 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC274721 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC274721 THRB 2 Median: 26651.35
Range: 25118.9 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC274721 MAPK1 2 Median: 17039
Range: 14125.4 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC87125 CYP3A4 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC87125 TDP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 KDM4E 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC225710 FUT4 1 14000 IC50 DOI: 10.1039/C4MD00086B
NPC274721 KDM4E 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC274721 HSD17B10 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87125 LMNA 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862