Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC103540 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 TDP1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264166 CYP2C9 1 32000 Ki PMID: 14761192
NPC264166 TSHR 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC264166 SLC22A1 2 Median: 68600
Range: 23400 to 113800
IC50 PMID: 10027858
PMID: 18788725
NPC264166 CACNA1C 1 19820 IC50 PMID: 22761000
NPC264166 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC47059 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC47059 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC47059 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC47059 KDM4E 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC103540 HTT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC149618 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC264166 ALDH1A1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC264166 SLC47A1 1 11200 IC50 PMID: 23241029