Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC127447 TSHR 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC236769 ABCC1 1 50000 IC50 PMID: 21354800
NPC236769 ABCB1 1 16000 IC50 PMID: 21354800
NPC242895 THRB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC242895 SLC16A3 1 41000 IC50 PMID: 11101640
NPC242895 SLC28A3 1 32280 Ki PMID: 19097778
NPC242895 TP53 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC242895 MAPK1 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC242895 GAA 1 31381.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC242895 KDM4E 3 Median: 31622.8
Range: 28183.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 ALDH1A1 2 Median: 33997.25
Range: 28183.8 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 ATM 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC242895 HPGD 3 Median: 31622.8
Range: 25118.9 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 CYP2D6 2 Median: 32464.8
Range: 25118.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 TDP1 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC242895 SLC2A1 1 21400 IC50 PMID: 24200808
NPC242895 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC263670 DPP4 1 33110 IC50 DOI: 10.1039/C0MD00245C
NPC278556 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC278556 KDM4E 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC310259 KDM4E 2 Median: 33552.05
Range: 31622.8 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC310259 ABCC1 1 26350 IC50 PMID: 23851114
NPC310259 ABCB1 1 23400 IC50 PMID: 23851114
NPC310259 ALDH1A1 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87231 MAPT 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 HSD17B10 2 Median: 18854.1
Range: 12589.3 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 MAPT 4 Median: 14219.1
Range: 12589.3 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC242895 RECQL 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC87231 NPSR1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 TP53 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC99240 HPGD 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862