Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC203719 HPGD 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203719 ABAT 1 17100 IC50 PMID: 16290145
NPC203719 ALDH5A1 1 15600 IC50 PMID: 16290145
NPC203719 ALDH1A1 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219913 ALDH5A1 1 24700 IC50 PMID: 16290145
NPC219913 ABAT 1 16500 IC50 PMID: 16290145
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC257188 MAPT 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 KDM4E 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC257188 HPGD 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC257188 CA12 1 25700 Ki PMID: 22892213
NPC257188 CA1 1 21500 Ki PMID: 22892213
NPC257188 SMN1;SMN2 1 14125.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51146 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51146 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51146 HSD17B10 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51146 MAOA 1 21300 IC50 PMID: 23517722
NPC81010 ESR1 1 16120 EC50 PMID: 23608764
NPC81010 HCAR2 1 14000 Ki PMID: 21167710