Plant ingredients against the target with activities between 10uM and 50uM
| Ingredient ID | Target (Gene Symbol) | No. of Activity Values | Activity Value (nM) | Activity Type | Activity Reference |
|---|---|---|---|---|---|
| NPC133671 | P4HB | 1 | 19020 | AC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | MAPT | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC176740 | EPHX2 | 1 | 24300 | IC50 |
PMID: 24679441 |
| NPC176740 | KDM4E | 1 | 14125.4 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | EPHX2 | 1 | 28430 | IC50 |
PMID: 24679441 |
| NPC179950 | XDH | 1 | 26310 | IC50 |
PMID: 12444671 |
| NPC179950 | MAPT | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC181465 | XDH | 1 | 14800 | IC50 |
PMID: 9461655 |
| NPC294409 | AKR1B10 | 1 | 36100 | IC50 |
PMID: 26529431 |
| NPC294409 | HPGD | 1 | 35481.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | KDM4E | 2 |
Median: 33552.05 Range: 31622.8 to 35481.3 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CYP2D6 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | HSD17B10 | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | LMNA | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CYP3A4 | 2 |
Median: 19952.6 Range: 19952.6 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | SMN1;SMN2 | 2 |
Median: 18867.7 Range: 17782.8 to 19952.6 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | MAPK1 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | ALOX12 | 1 | 15848.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SYK | 1 | 39000 | IC50 |
PMID: 19254842 |
| NPC39426 | ALDH1A1 | 2 |
Median: 37646 Range: 35481.3 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | NR1H3 | 1 | 31000 | IC50 |
PMID: 18343126 |
| NPC39426 | DNMT1 | 1 | 30000 | IC50 |
PMID: 25406944 |
| NPC39426 | ODC1 | 1 | 26000 | IC50 |
PMID: 10075742 |
| NPC39426 | PKM | 2 |
Median: 25118.9 Range: 25118.9 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SMN1;SMN2 | 3 |
Median: 25118.9 Range: 22387.2 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | NR1H2 | 1 | 22000 | IC50 |
PMID: 18343126 |
| NPC39426 | AKR1B1 | 1 | 20000 | IC50 |
PMID: 22261024 |
| NPC39426 | ALOX15 | 2 |
Median: 25787.7 Range: 19952.6 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | ADORA1 | 1 | 19904 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | ADORA2A | 1 | 17442 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | PMP22 | 1 | 16944.1 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | SLC6A3 | 1 | 16918 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC39426 | HSD17B2 | 1 | 16500 | IC50 |
PMID: 18533708 |
| NPC39426 | LMNA | 2 |
Median: 15848.9 Range: 15848.9 to 15848.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HTR2C | 1 | 14910 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC48342 | CACNA1C | 1 | 50000 | IC50 |
PMID: 22761000 |
| NPC48342 | NR3C1 | 1 | 41422 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC48342 | TSHR | 2 |
Median: 39810.7 Range: 39810.7 to 39810.7 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | GPBAR1 | 1 | 38400 | EC50 |
PMID: 18307294 |
| NPC48342 | ALDH1A1 | 1 | 37650.5 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | RECQL | 1 | 31622.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | HSD17B10 | 2 |
Median: 22535.75 Range: 19952.6 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC48342 | SLC6A3 | 1 | 14911 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC64359 | LMNA | 1 | 35481.3 | Potency |
PMID: 18278869 |
| NPC64359 | ABCG2 | 2 |
Median: 30985 Range: 30950 to 31020 |
IC50 |
PMID: 12444673 PMID: 18054490 |
| NPC64359 | MAPT | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC64359 | ATM | 1 | 19952.6 | Potency |
PMID: 23290052 |
| NPC94045 | ALDH1A1 | 1 | 39810.7 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | CYP3A4 | 2 |
Median: 31622.8 Range: 31622.8 to 31622.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | HPGD | 1 | 28183.8 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | SMN1;SMN2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | USP2 | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | KDM4E | 1 | 25118.9 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | HSD17B10 | 1 | 19952.6 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | MAPT | 2 |
Median: 24068.2 Range: 19952.6 to 28183.8 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC94045 | TRPV1 | 3 |
Median: 23700 Range: 15000 to 30000 |
IC50 |
PMID: 26750258 PMID: 26750258 PMID: 26750258 |
| NPC179950 | ALPL | 1 | 14000 | IC50 |
PubChem BioAssay data set CHEMBL1201862 |
| NPC179950 | KDM4E | 1 | 12589.3 | Potency |
PubChem BioAssay data set CHEMBL1201862 |
| NPC294409 | CBR1 | 1 | 12710 | IC50 |
PMID: 19097799 |
| NPC39426 | HPGD | 4 |
Median: 19952.6 Range: 11220.2 to 25118.9 |
Potency |
PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 PubChem BioAssay data set CHEMBL1201862 |
| NPC39426 | HTR2A | 1 | 10469 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC48342 | SLC6A4 | 1 | 10755 | IC50 |
DrugMatrix in vitro pharmacology data CHEMBL1909046 |
| NPC64359 | L3MBTL1 | 1 | 12589.3 | Potency |
PMID: 24456556 |