Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC107135 ALDH1A1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC107135 TSHR 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC125732 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 CYP2C19 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC125732 HTR3A 1 26000 EC50 PMID: 18033297
NPC1591 SMN1;SMN2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC1591 CHRNA3 4 Median: 81976.31
Range: 19000 to 144543.98
EC50 PMID: 18989912
PMID: 18989912
PMID: 19027295
PMID: 19027295
NPC209296 KMT2A 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC209296 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC224651 EGLN1 2 Median: 119500
Range: 19000 to 220000
IC50 PMID: 18942826
PMID: 23234607
NPC74881 CD38 1 37900 IC50 PMID: 21641214
NPC79056 POLB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC79056 CTDSP1 1 20733 IC50 PubChem BioAssay data set
CHEMBL1201862
NPC125732 L3MBTL1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862