Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC216630 PPARG 1 30000 IC50 DOI: 10.1007/s00044-012-0285-6
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC285829 KAT2B 1 50000 IC50 PMID: 26701186
NPC285829 TDP1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC285829 BLM 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC285829 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC285829 ERBB2 1 30800 IC50 PMID: 24355130
NPC285829 SMN1;SMN2 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC285829 RAF1 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC285829 HPGD 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC285829 RECQL 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC285829 CASP7 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC285829 ALDH1A1 2 Median: 27829.8
Range: 15848.9 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC289883 ELANE 1 39000 IC50 PMID: 1578486
NPC307174 PIM1 1 28000 IC50 PMID: 27173800
NPC44830 RXFP1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC44830 MAPT 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 GLA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 GAA 2 Median: 40074.85
Range: 35481.3 to 44668.4
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 RECQL 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA13 1 17800 Ki PMID: 22892213
NPC285829 HSD17B10 2 Median: 26200
Range: 12589.3 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC285829 CASP1 2 Median: 22106.05
Range: 12589.3 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC285829 MAP2K1 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC76336 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC76336 CA1 1 10560 Ki PMID: 22892213