Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC100079 RAB9A 1 46109.1 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP2C9 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 MAPK1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 HIF1A 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 USP2 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 TSHR 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 CYP2D6 1 25118.86 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC100079 HPGD 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 HSD17B10 2 Median: 22535.75
Range: 19952.6 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 ALDH1A1 2 Median: 19118.05
Range: 15848.9 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100079 MAPT 4 Median: 15848.9
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100551 CA14 1 49800 Ki PMID: 18579385
NPC100551 ALDH1A1 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100551 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 KDM4E 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100551 HPGD 2 Median: 29903.3
Range: 28183.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC17810 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC17810 ALDH1A1 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC229147 CYP19A1 1 30000 IC50 PMID: 11678652
NPC230301 DPP4 1 28840 IC50 DOI: 10.1039/C0MD00245C
NPC230301 POLB 1 26300 IC50 PMID: 14640519
NPC234952 ESR2 1 41700 IC50 PMID: 20493686
NPC8283 ESR1 1 26200 IC50 PMID: 20493686
NPC8283 ESR2 1 14700 IC50 PMID: 20493686
NPC100079 ALOX12 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC100079 NFKB1 2 Median: 11220.2
Range: 11220.2 to 11220.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC100551 CA6 2 Median: 1165950
Range: 11900 to 2320000
Ki PMID: 18579385
PMID: 21669522
NPC100551 CA4 1 11100 Ki PMID: 18579385