Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC181465 XDH 1 14800 IC50 PMID: 9461655
NPC243728 POLB 1 26500 IC50 PMID: 15165161
NPC262359 MAPK1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC262359 ALDH1A1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC262359 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC262359 HPGD 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC262359 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC262359 ALOX15 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC262359 TP53 2 Median: 25787.7
Range: 19952.6 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294409 AKR1B10 1 36100 IC50 PMID: 26529431
NPC294409 HPGD 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294409 KDM4E 2 Median: 33552.05
Range: 31622.8 to 35481.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294409 CYP2D6 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294409 HSD17B10 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294409 LMNA 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294409 CYP3A4 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294409 SMN1;SMN2 2 Median: 18867.7
Range: 17782.8 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294409 MAPK1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC294409 ALOX12 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC80710 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC80710 MAPT 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC80710 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC192638 TOP2A 1 10400 IC50 PMID: 11754608
NPC262359 ABCG2 2 Median: 22685
Range: 12050 to 33320
IC50 PMID: 22112540
PMID: 22112540
NPC262359 MAPT 2 Median: 13534.55
Range: 11220.2 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC294409 CBR1 1 12710 IC50 PMID: 19097799