Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC119133 CYP3A4 2 Median: 25118.9
Range: 25118.9 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC126029 TSHR 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC126681 SLC6A9 1 31600 IC50 PMID: 24461352
NPC156654 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203468 TSHR 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203468 MAPT 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203468 LMNA 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC203468 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219143 CYP1A2 1 39810.72 AC50 PubChem BioAssay data set
CHEMBL1201862
NPC219143 KDM4E 2 Median: 39810.7
Range: 39810.7 to 39810.7
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 HSD17B10 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 PTGS1 2 Median: 58350
Range: 36700 to 80000
IC50 PMID: 11858749
PMID: 16038536
NPC219876 SMN1;SMN2 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 NPSR1 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 BLM 2 Median: 28183.8
Range: 28183.8 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 ALDH1A1 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 RECQL 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC219876 MAPT 2 Median: 19952.6
Range: 19952.6 to 19952.6
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 APEX1 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC256849 ADORA1 5 Median: 44900
Range: 44000 to 44900
Ki PMID: 21664729
PMID: 23602401
PMID: 24139167
PMID: 24139167
PMID: 24164628
NPC256849 ADORA2A 1 20472 IC50 DrugMatrix in vitro pharmacology data
CHEMBL1909046
NPC279406 MMP2 1 31400 IC50 PMID: 20053563
NPC33338 CYP2C9 1 15848.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC46335 MMP2 1 43200 IC50 PMID: 20053563
NPC46335 MMP9 1 39200 IC50 PMID: 20053563
NPC51146 KDM4E 1 31622.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC51146 CYP3A4 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51146 HSD17B10 2 Median: 31622.8
Range: 31622.8 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC51146 MAOA 1 21300 IC50 PMID: 23517722
NPC126029 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC126029 KDM4E 2 Median: 16803.7
Range: 11220.2 to 22387.2
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC203468 HIF1A 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 KDM4E 2 Median: 19622.15
Range: 14125.4 to 25118.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC219876 POLB 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC256849 ADORA3 3 Median: 13300
Range: 13300 to 13300
Ki PMID: 12139454
PMID: 24139167
PMID: 24139167
NPC256849 ADORA2B 10 Median: 27150
Range: 10400 to 33800
Ki PMID: 12014951
PMID: 19569717
PMID: 19569717
PMID: 20188574
PMID: 20537438
PMID: 21664729
PMID: 24139167
PMID: 24139167
PMID: 24164628
PMID: 26824742
NPC256849 GDA 1 10200 Ki PMID: 20716488
NPC277510 HDAC11 1 12900 IC50 PMID: 24328302
NPC33338 TSHR 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC33338 KDM4E 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862