Putative targets based on weak experimental activity

Plant ingredients against the target with activities between 10uM and 50uM


Ingredient ID Target (Gene Symbol) No. of Activity Values Activity Value (nM) Activity Type Activity Reference
NPC156654 L3MBTL1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC156654 POLB 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC238861 BLM 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC238861 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC238861 HSD17B10 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC238861 CASP7 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC238861 HPGD 2 Median: 24068.2
Range: 19952.6 to 28183.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC238861 CYP3A4 2 Median: 15848.9
Range: 15848.9 to 15848.9
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC289432 THRB 1 44668.4 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 RECQL 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 TDP1 1 39810.7 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 KDM4E 1 35481.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 BLM 1 28183.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 LMNA 1 22387.2 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 HSD17B10 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 TP53 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 ALDH1A1 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 HPGD 1 17782.8 Potency PubChem BioAssay data set
CHEMBL1201862
NPC289432 MAPK1 2 Median: 23735.85
Range: 15848.9 to 31622.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC71074 PTPN6 1 24560 IC50 PMID: 18707891
NPC71074 PYGM 1 20000 IC50 PMID: 16169219
NPC93241 CES1 1 26250 Ki PMID: 23286284
NPC93241 BLM 1 25118.9 Potency PubChem BioAssay data set
CHEMBL1201862
NPC93241 POLB 1 19952.6 Potency PubChem BioAssay data set
CHEMBL1201862
NPC238861 TDP1 2 Median: 15954.1
Range: 14125.4 to 17782.8
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC238861 RECQL 2 Median: 56294.65
Range: 12589.3 to 100000
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC289432 CYP3A4 2 Median: 12589.3
Range: 12589.3 to 12589.3
Potency PubChem BioAssay data set
CHEMBL1201862
PubChem BioAssay data set
CHEMBL1201862
NPC71074 POLB 1 12600 IC50 PMID: 15165161
NPC71074 HTT 1 12589.3 Potency PubChem BioAssay data set
CHEMBL1201862
NPC71074 PTPN2 1 11310 IC50 PMID: 18707891
NPC93241 TDP1 1 11220.2 Potency PubChem BioAssay data set
CHEMBL1201862