Records matched to the searched keyword "STS-135"

Matched Space Investigations


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Study IDs Study Titles Investigation Categories Studied Biophysical Phenomena Associated Disease conditions Studied Biological Phenomena
SLID-041 Effects of spaceflight on the murine mandible: Possible factors mediating skeletal changes in non-weight bearing bones of the head Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Bone;
●n.a.
 ●Bone loss
 ●Musculoskeletal system - Bone properties ---> Skull remodeling
●Musculoskeletal system - Bone properties ---> Bone volume
●Musculoskeletal system - Bone properties ---> Mineral density
●Musculoskeletal system - Bone properties ---> Mineral content
SLID-046 Responses to spaceflight of mouse mandibular bone and teeth Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6J;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Bone; Teeth;
●n.a.
 ●Bone loss
●Development impairment
 ●Musculoskeletal system - Teeth properties ---> Teeth proteins
●Musculoskeletal system - Teeth properties ---> Teeth development retardation
●Musculoskeletal system - Teeth properties ---> Teeth mineralization
●Musculoskeletal system - Bone properties ---> Bone structure
SLID-048 Multiscale effects of spaceflight on murine tendon and bone Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6J;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Tendon; Bone;
●n.a.
 ●Bone loss
●Tendon decline
 ●Musculoskeletal system - Bone properties ---> Bone composition
●Musculoskeletal system - Bone properties ---> Bone structure
●Musculoskeletal system - Bone properties ---> Bone mechanics
●Musculoskeletal system - Tendon properties ---> Fibril diameter
SLID-080 Effects of spaceflight on the mouse submandibular gland Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6J;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Submandibular gland; Saliva;
●n.a.
 ●n.a.
 ●Nervous and regulatory systems - Endocrine function ---> Secretory protein expression
SLID-093 Effects of spaceflight and ground recovery on mesenteric artery and vein constrictor properties in mice Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Vessel;
●Fluid dynamics - Hemodynamics
 ●Unstable blood pressure
 ●Cardiovascular and Immune System - Cardiovascular properties ---> Blood pressure
●Cardiovascular and Immune System - Cardiovascular properties ---> Vessel morphology
●Cardiovascular and Immune System - Cardiovascular properties ---> Mesenteric artery
●Cardiovascular and Immune System - Cardiovascular properties ---> Vein constrictor properties
●Cardiovascular and Immune System - Cardiovascular properties ---> Vasoconstrictor responses
●Cardiovascular and Immune System - Cardiovascular properties ---> Orthostatic stress
●Other profiles - Medication use ---> Norepinephrine
●Other profiles - Medication use ---> Potassium chloride
●Other profiles - Medication use ---> Caffeine
SLID-318 Spaceflight promotes biofilm formation by Pseudomonas aeruginosa Investigated Organism: Pseudomonas aeruginosa;
Studied Organism Strains: PA14;
Organism Common Name: n.a.;
Organism Class:
Organism Category: Bacteria;
Microbe Type: Human opportunistic pathogen;
Microbe Form: Active organism;
●Polymer network-Biofilm ---> Biofilm formation
 ●n.a.
 ●Cell behavior - Survival and growth ---> Viable cell number
●Morphology - Biofilm
●Cell behavior - Motility
SLID-419 Biological and metabolic response in STS-135 space-flown mouse skin Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Skin;
●Oxidative damage
SLID-423 Effects of spaceflight on the muscles of the murine shoulder Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Muscle;
●n.a.
 ●Muscle atrophy
 ●Musculoskeletal system - Muscle properties ---> Muscle structure
●Musculoskeletal system - Muscle properties ---> Muscle proteins
●Omics - Proteome ---> Muscle
SLID-429 Is spaceflight-induced immune dysfunction linked to systemic changes in metabolism? Investigated Organism: Mus musculus;
Studied Organism Strains: C57BL/6;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Spleen; Liver; Spleen; Adrenal gland;
●n.a.
 ●Immune system dysregulation
●Oxidative damage
 ●Cardiovascular and Immune System - Immune function ---> Blood cell population
●Cardiovascular and Immune System - Immune function ---> Splenocyte viability
●Omics - Metabolome ---> Liver
●Omics - Transcriptome ---> Liver
●Nervous and regulatory systems - Endocrine function ---> Adrenal hormones
SLID-435 Response of the mouse sublingual gland to spaceflight Investigated Organism:
Studied Organism Strains: C57BL/6;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Sublingual salivary gland;
●n.a.
 ●n.a.
 ●Nervous and regulatory systems - Endocrine function ---> Sublingual salivary glands morphology
●Nervous and regulatory systems - Endocrine function ---> Sublingual salivary glands protein expression
SLID-436 Retinal non-visual photoreception in space Investigated Organism: Mus musculus;
Studied Organism Strains: BALB/cJ,C57BL;
Organism Common Name: Mice;
Organism Class: Mammalia;
Studied Organ/Tissue/Part: Eye;
●n.a.
 ●n.a.
 ●Nervous and regulatory systems - Eye properties ---> Retina cell survival
●Nervous and regulatory systems - Eye properties ---> Retina gene expression