<%@LANGUAGE="VBSCRIPT"%> <%Option Explicit%> TTD: Therapeutic Target Database
Therapeutic Targets Database
BIDD Pharmainformatics Databases

Therapeutic Target Database

Therapeutic Target Database (TTD) is a database to provide information about the known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs directed at each of these targets. Also included in this database are links to relevant databases containing information about target function, sequence, 3D structure, ligand binding properties, enzyme nomenclature and drug structure, therapeutic class, clinical development status. All information provided are fully referenced.


TTD Version 4.3.02 release on Aug 25th 2011. New version of TTD provides Quantitative Structure-Activity Relationship (QSAR) models and Target Validation Information for TTD drug target. Moreover, Multi Target Agents Data with structure and potency information, Drug Combinations and Nature-derived Drugs together with drug species origin data are also included.

Statistics of this database

This database currently contains 2,025 targets, including 364 successful, 286 clinical trial, 44 discontinued and 1,331 research targets, 17,816 drugs, including 1,540 approved, 1,423 clinical trial, 14,853 experimental drugs and 3,681 multi-target agents (14,170 small molecules and 652 antisense drugs with available strucuture or oligonucleotide sequence). Targets and drugs in this database cover 61 protein biochemical class and 140 drug therapeutic classes respectively.

How to cite our database

Zhu F, Han BC, Pankaj Kumar, Liu XH, Ma XH, Wei XN, Huang L, Guo YF, Han LY, Zheng CJ, Chen YZ. Update of TTD: Therapeutic Target Database. Nucleic Acids Res. 38(suppl 1):D787-91, 2010. PubMed

Chen X, Ji ZL, Chen YZ. TTD: Therapeutic Target Database. Nucleic Acids Res. 30(1):412-415, 2002. PubMed

Last update by

Aug 25th, 2011


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Professor in Department of Pharmacy
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