Prescription Description
| Prescription ID | TCMFx6499 |
| Pinyin Name | Yu Feng Ning Xin Pian |
| Chinese Name | 愈风宁心片 |
| English Name | Yu Feng Ning Xin Tablets |
| Function Description | 眩晕, 头痛, 项痹, 胸痹, 耳聋 |
| Indications | Vertigo disorder, Hypertension, Headache, Coronary heart disease, Angina pectoris, Deafness |
| Disease ICD-11 Category |
SD22 [Vertigo disorder (TM1), 眩晕 (TM1)
]; BA2Z [Hypotension, unspecified, 低血压，未特指的 ]; MB6Y [Other specified symptoms or signs involving the nervous system, 其他特指的累及神经系统的症状或体征 ]; BA80.Z [Coronary atherosclerosis, unspecified site, 冠状动脉粥样硬化,未特指部位 ]; BA40 [Angina pectoris, 心绞痛 ]; AB52 [Deafness not otherwise specified, 聋，其他方面未特指 ]; |
| Human Tissues Associated with Indication | Heart, Lung, Brain |
| Reference | CFDA |
| Reference Book/link | http://samr.cfda.gov.cn/WS01/CL0001/ |
Prescription Components
| Component ID | Latin Name | Chinese Name | Component Quantity | Barcode |
|---|---|---|---|---|
| TCMH677 | Pueraria lobata | 葛根 | TCMH677 | ITSAJ4206-14 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT136 | CA12 | Carbonic anhydrase XII | Lyase | O43570 |
| TCMT138 | CA7 | Carbonic anhydrase VII | Lyase | P43166 |
| TCMT142 | CA4 | Carbonic anhydrase IV | Lyase | P22748 |
| TCMT162 | UGT1A1 | UDP-glucuronosyltransferase 1-1 | Transferase | P22309 |
| TCMT236 | ESR2 | Estrogen receptor beta | Nuclear receptor | Q92731 |
| TCMT344 | AOX1 | Aldehyde oxidase | Oxidoreductase | Q06278 |
| TCMT591 | ESRRA | Estrogen-related receptor alpha | Nuclear receptor | P11474 |
| TCMT82 | ESR1 | Estrogen receptor alpha | Nuclear receptor | P03372 |
| TCMT910 | ESRRB | Estrogen-related receptor beta | Nuclear receptor | O95718 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1227 | Streptococcus |
| TCMT1246 | Escherichia coli |
| TCMT1284 | Penicillium expansum |
| TCMT1438 | Plasmodium falciparum |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples