Prescription Description
| Prescription ID | TCMFx1204 |
| Pinyin Name | Dai Ge San |
| Chinese Name | 黛蛤散 |
| English Name | Daige Powder, Isatis Venerupis Powder |
| Function Description | 眩晕, 耳鸣, 咳嗽, 肺痿, 肺痈 |
| Indications | Lung withering disorder, Tinnitus disorder, Vertigo disorder, Upper respiratory infection(uri) |
| Disease ICD-11 Category |
SA85 [Lung withering disorder (TM1), 肺痿 (TM1)
]; SC75 [Tinnitus disorder (TM1), 耳鸣 (TM1) ]; SD22 [Vertigo disorder (TM1), 眩晕 (TM1) ]; CA0Z [Upper respiratory tract disorders, unspecified, 上呼吸道疾患，未特指的 ]; |
| Human Tissues Associated with Indication | Brain, Lung |
| Reference | Chinese pharmacopoeia (2015) |
| Reference Book/link | ISBN 978-7-5067-7337-9 |
Targeted Human Proteins by the Ingredients of Prescription
| Target ID | Gene Symbol | Target Name | Target Class | Uniprot ID |
|---|---|---|---|---|
| TCMT130 | ALOX5 | Arachidonate 5-lipoxygenase | Oxidoreductase | P09917 |
| TCMT30 | PTGS2 | Cyclooxygenase-2 | Oxidoreductase | P35354 |
| TCMT336 | IDO1 | Indoleamine 2,3-dioxygenase | Oxidoreductase | P14902 |
| TCMT689 | TGM2 | Protein-glutamine gamma-glutamyltransferase | Transferase | P21980 |
| TCMT907 | FDPS | Farnesyl diphosphate synthase | Lyase | P14324 |
Targeted Pathogenic Microbes by the Ingredients of Prescription
| Target ID | Target Name |
|---|---|
| TCMT1218 | Staphylococcus aureus |
| TCMT1226 | Klebsiella pneumoniae |
| TCMT1246 | Escherichia coli |
| TCMT1251 | Candida albicans |
| TCMT1353 | Plasmodium yoelii |
| TCMT1438 | Plasmodium falciparum |
| TCMT1439 | Mycobacterium smegmatis |
| TCMT1442 | Leishmania donovani |
| TCMT1455 | Mycobacterium tuberculosis H37Rv |
| TCMT1458 | Filobasidiella neoformans |
| TCMT1463 | Mycobacterium tuberculosis |
| TCMT1465 | Entamoeba histolytica |
Gene Ontology Associated to Targeted Human Proteins
| GO Term | GO Name | Enriched Genes | Log10 Adjusted P-value |
|---|
KEGG Pathways Associated to Targeted Human Proteins
| KEGG Pathway ID | Enriched Genes | Log10 Adjusted P-value |
|---|
Target Exprsssion in Healthy Human Tissues (protein & mRNA level)
Protein expression data was from the "Human Proteome Map" datasetmRNA expression data was from the "GTEx" dataset
Average Target Expression (Fold Change) in Multiple Disease Conditions
Fold Change with Corresponding Normal SamplesClick each cell within the heatmap to access gene expression of individual patient samples