Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT153 | Individual Protein | Androgen Receptor | Homo sapiens | Potency | 9770 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 61644.8 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 68589.6 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 48966.2 | nM | PubChem BioAssay data set |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC48930 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.881 | High Similarity | NPC239754 |
0.8605 | High Similarity | NPC110234 |
0.8605 | High Similarity | NPC163751 |
0.8605 | High Similarity | NPC44363 |
0.75 | Intermediate Similarity | NPC234829 |
0.7368 | Intermediate Similarity | NPC179831 |
0.7368 | Intermediate Similarity | NPC254713 |
0.7368 | Intermediate Similarity | NPC261991 |
0.7368 | Intermediate Similarity | NPC49151 |
0.7368 | Intermediate Similarity | NPC262505 |
0.7273 | Intermediate Similarity | NPC67920 |
0.7273 | Intermediate Similarity | NPC287397 |
0.7273 | Intermediate Similarity | NPC298710 |
0.7234 | Intermediate Similarity | NPC324812 |
0.7234 | Intermediate Similarity | NPC216130 |
0.7045 | Intermediate Similarity | NPC33489 |
0.7021 | Intermediate Similarity | NPC195246 |
0.7021 | Intermediate Similarity | NPC22098 |
0.7021 | Intermediate Similarity | NPC276009 |
0.7 | Intermediate Similarity | NPC49615 |
0.6905 | Remote Similarity | NPC220061 |
0.6875 | Remote Similarity | NPC180534 |
0.6863 | Remote Similarity | NPC71761 |
0.6744 | Remote Similarity | NPC92863 |
0.6744 | Remote Similarity | NPC155880 |
0.6739 | Remote Similarity | NPC106819 |
0.6667 | Remote Similarity | NPC301919 |
0.6667 | Remote Similarity | NPC161366 |
0.6604 | Remote Similarity | NPC28779 |
0.6604 | Remote Similarity | NPC128061 |
0.6604 | Remote Similarity | NPC10316 |
0.6604 | Remote Similarity | NPC200845 |
0.6604 | Remote Similarity | NPC223677 |
0.6604 | Remote Similarity | NPC188789 |
0.66 | Remote Similarity | NPC224227 |
0.6596 | Remote Similarity | NPC114841 |
0.6591 | Remote Similarity | NPC33761 |
0.6579 | Remote Similarity | NPC32279 |
0.6538 | Remote Similarity | NPC139545 |
0.6538 | Remote Similarity | NPC309606 |
0.6538 | Remote Similarity | NPC39633 |
0.6522 | Remote Similarity | NPC208936 |
0.6512 | Remote Similarity | NPC216416 |
0.6512 | Remote Similarity | NPC69245 |
0.6471 | Remote Similarity | NPC262968 |
0.6471 | Remote Similarity | NPC477458 |
0.6415 | Remote Similarity | NPC209431 |
0.6415 | Remote Similarity | NPC100809 |
0.64 | Remote Similarity | NPC145311 |
0.6346 | Remote Similarity | NPC22182 |
0.6346 | Remote Similarity | NPC281245 |
0.6346 | Remote Similarity | NPC18357 |
0.6327 | Remote Similarity | NPC100380 |
0.6296 | Remote Similarity | NPC228473 |
0.6279 | Remote Similarity | NPC213767 |
0.6275 | Remote Similarity | NPC474391 |
0.6226 | Remote Similarity | NPC139029 |
0.6226 | Remote Similarity | NPC294548 |
0.6226 | Remote Similarity | NPC36061 |
0.6226 | Remote Similarity | NPC1813 |
0.6216 | Remote Similarity | NPC38513 |
0.6167 | Remote Similarity | NPC268039 |
0.6154 | Remote Similarity | NPC198118 |
0.6154 | Remote Similarity | NPC38859 |
0.614 | Remote Similarity | NPC473652 |
0.6136 | Remote Similarity | NPC279300 |
0.6111 | Remote Similarity | NPC424 |
0.6111 | Remote Similarity | NPC290563 |
0.6111 | Remote Similarity | NPC95581 |
0.6111 | Remote Similarity | NPC25417 |
0.6111 | Remote Similarity | NPC261831 |
0.6111 | Remote Similarity | NPC87564 |
0.6111 | Remote Similarity | NPC32467 |
0.6111 | Remote Similarity | NPC88966 |
0.6111 | Remote Similarity | NPC281972 |
0.6111 | Remote Similarity | NPC6095 |
0.6111 | Remote Similarity | NPC250539 |
0.6111 | Remote Similarity | NPC154245 |
0.6111 | Remote Similarity | NPC85813 |
0.6087 | Remote Similarity | NPC323278 |
0.6087 | Remote Similarity | NPC18205 |
0.6087 | Remote Similarity | NPC12319 |
0.6087 | Remote Similarity | NPC101147 |
0.6078 | Remote Similarity | NPC163345 |
0.6078 | Remote Similarity | NPC250919 |
0.6053 | Remote Similarity | NPC59581 |
0.6053 | Remote Similarity | NPC266144 |
0.6053 | Remote Similarity | NPC31891 |
0.6053 | Remote Similarity | NPC266539 |
0.6053 | Remote Similarity | NPC287191 |
0.6047 | Remote Similarity | NPC218357 |
0.6038 | Remote Similarity | NPC310746 |
0.6038 | Remote Similarity | NPC473705 |
0.6038 | Remote Similarity | NPC92114 |
0.6034 | Remote Similarity | NPC143857 |
0.6034 | Remote Similarity | NPC243532 |
0.6034 | Remote Similarity | NPC229252 |
0.6034 | Remote Similarity | NPC45097 |
0.6 | Remote Similarity | NPC79887 |
0.6 | Remote Similarity | NPC200258 |
0.6 | Remote Similarity | NPC4962 |
0.6 | Remote Similarity | NPC222997 |
0.6 | Remote Similarity | NPC196434 |
0.6 | Remote Similarity | NPC42403 |
0.6 | Remote Similarity | NPC153439 |
0.6 | Remote Similarity | NPC29561 |
0.6 | Remote Similarity | NPC54766 |
0.6 | Remote Similarity | NPC221192 |
0.5962 | Remote Similarity | NPC473487 |
0.5962 | Remote Similarity | NPC59051 |
0.5932 | Remote Similarity | NPC201939 |
0.5926 | Remote Similarity | NPC321062 |
0.5926 | Remote Similarity | NPC70387 |
0.5918 | Remote Similarity | NPC25771 |
0.5909 | Remote Similarity | NPC75204 |
0.5893 | Remote Similarity | NPC477201 |
0.5893 | Remote Similarity | NPC187777 |
0.5893 | Remote Similarity | NPC18951 |
0.5893 | Remote Similarity | NPC179764 |
0.5882 | Remote Similarity | NPC207292 |
0.587 | Remote Similarity | NPC217923 |
0.5854 | Remote Similarity | NPC168982 |
0.5849 | Remote Similarity | NPC236623 |
0.5849 | Remote Similarity | NPC27438 |
0.5849 | Remote Similarity | NPC470410 |
0.5849 | Remote Similarity | NPC470412 |
0.5849 | Remote Similarity | NPC30433 |
0.5833 | Remote Similarity | NPC473674 |
0.5833 | Remote Similarity | NPC54925 |
0.5833 | Remote Similarity | NPC149668 |
0.5818 | Remote Similarity | NPC202850 |
0.5818 | Remote Similarity | NPC137538 |
0.5818 | Remote Similarity | NPC63396 |
0.58 | Remote Similarity | NPC172042 |
0.5789 | Remote Similarity | NPC88325 |
0.5789 | Remote Similarity | NPC225929 |
0.5778 | Remote Similarity | NPC185839 |
0.5769 | Remote Similarity | NPC149821 |
0.5769 | Remote Similarity | NPC207815 |
0.5769 | Remote Similarity | NPC5413 |
0.5769 | Remote Similarity | NPC473551 |
0.575 | Remote Similarity | NPC179103 |
0.575 | Remote Similarity | NPC295442 |
0.575 | Remote Similarity | NPC76765 |
0.5745 | Remote Similarity | NPC113082 |
0.5738 | Remote Similarity | NPC328089 |
0.5738 | Remote Similarity | NPC68343 |
0.5738 | Remote Similarity | NPC470320 |
0.5714 | Remote Similarity | NPC474672 |
0.5714 | Remote Similarity | NPC225318 |
0.5714 | Remote Similarity | NPC52264 |
0.5714 | Remote Similarity | NPC301972 |
0.5714 | Remote Similarity | NPC292463 |
0.5714 | Remote Similarity | NPC274290 |
0.5714 | Remote Similarity | NPC76608 |
0.5714 | Remote Similarity | NPC290350 |
0.5714 | Remote Similarity | NPC4370 |
0.5714 | Remote Similarity | NPC193770 |
0.5714 | Remote Similarity | NPC275472 |
0.5714 | Remote Similarity | NPC473863 |
0.5714 | Remote Similarity | NPC16578 |
0.5714 | Remote Similarity | NPC252978 |
0.5714 | Remote Similarity | NPC268596 |
0.5714 | Remote Similarity | NPC149101 |
0.569 | Remote Similarity | NPC34416 |
0.5686 | Remote Similarity | NPC474204 |
0.5682 | Remote Similarity | NPC72258 |
0.5667 | Remote Similarity | NPC168407 |
0.566 | Remote Similarity | NPC301482 |
0.566 | Remote Similarity | NPC32351 |
0.5652 | Remote Similarity | NPC180840 |
0.5645 | Remote Similarity | NPC245947 |
0.5645 | Remote Similarity | NPC136164 |
0.5645 | Remote Similarity | NPC326268 |
0.5645 | Remote Similarity | NPC255863 |
0.5645 | Remote Similarity | NPC318420 |
0.5645 | Remote Similarity | NPC296436 |
0.5645 | Remote Similarity | NPC133904 |
0.5645 | Remote Similarity | NPC176215 |
0.5636 | Remote Similarity | NPC61177 |
0.5636 | Remote Similarity | NPC284224 |
0.5636 | Remote Similarity | NPC474141 |
0.5625 | Remote Similarity | NPC155198 |
0.561 | Remote Similarity | NPC158107 |
0.56 | Remote Similarity | NPC108195 |
0.56 | Remote Similarity | NPC145755 |
0.56 | Remote Similarity | NPC267514 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC48930 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.6875 | Remote Similarity | NPD622 | Approved |
0.6471 | Remote Similarity | NPD29 | Approved |
0.6471 | Remote Similarity | NPD28 | Approved |
0.6226 | Remote Similarity | NPD3172 | Approved |
0.6122 | Remote Similarity | NPD3174 | Discontinued |
0.6111 | Remote Similarity | NPD3195 | Phase 2 |
0.6111 | Remote Similarity | NPD3194 | Approved |
0.6111 | Remote Similarity | NPD3196 | Approved |
0.6111 | Remote Similarity | NPD4266 | Approved |
0.5882 | Remote Similarity | NPD5343 | Approved |
0.5769 | Remote Similarity | NPD3173 | Approved |
0.5738 | Remote Similarity | NPD3197 | Phase 1 |
0.56 | Remote Similarity | NPD6096 | Approved |
0.56 | Remote Similarity | NPD6097 | Approved |
PubChem CID   | 8187 |
ChEMBL   | CHEMBL3185269 |
ZINC   |
Molecular Weight:   | 168.15 |
ALogP:   | -0.9225 |
MLogP:   | 2.56 |
XLogP:   | 4.773 |
# Rotatable Bonds:   | 9 |
Polar Surface Area:   | 17.07 |
# H-Bond Aceptor:   | 1 |
# H-Bond Donor:   | 0 |
# Rings:   | 0 |
# Heavy Atoms:   | 12 |