Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT2 | Others | Unspecified | IC50 | > | 50000 | nM | 17190457 | |
NPT2 | Others | Unspecified | IC50 | > | 50000 | nM | 20151678 | |
NPT91 | Cell Line | KB | Homo sapiens | IC50 | > | 50000 | nM | 20516287 |
NPT2 | Others | Unspecified | IC50 | = | 6320 | nM | 18693761 | |
NPT2 | Others | Unspecified | IC50 | = | 5.6 | nM | 9703468 | |
NPT2 | Others | Unspecified | IC50 | > | 50000 | nM | 23025331 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC470839 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.9474 | High Similarity | NPC470834 |
0.9091 | High Similarity | NPC470840 |
0.8725 | High Similarity | NPC470838 |
0.8431 | Intermediate Similarity | NPC237190 |
0.8208 | Intermediate Similarity | NPC44063 |
0.82 | Intermediate Similarity | NPC293086 |
0.8155 | Intermediate Similarity | NPC144956 |
0.8137 | Intermediate Similarity | NPC18509 |
0.8056 | Intermediate Similarity | NPC2766 |
0.802 | Intermediate Similarity | NPC212812 |
0.8019 | Intermediate Similarity | NPC137657 |
0.7981 | Intermediate Similarity | NPC112167 |
0.7921 | Intermediate Similarity | NPC109414 |
0.7864 | Intermediate Similarity | NPC192428 |
0.7822 | Intermediate Similarity | NPC168027 |
0.7822 | Intermediate Similarity | NPC185936 |
0.7822 | Intermediate Similarity | NPC248913 |
0.7798 | Intermediate Similarity | NPC177064 |
0.7767 | Intermediate Similarity | NPC470978 |
0.7767 | Intermediate Similarity | NPC279313 |
0.7767 | Intermediate Similarity | NPC470974 |
0.7757 | Intermediate Similarity | NPC194323 |
0.7755 | Intermediate Similarity | NPC36350 |
0.7723 | Intermediate Similarity | NPC191684 |
0.7723 | Intermediate Similarity | NPC183283 |
0.7714 | Intermediate Similarity | NPC222011 |
0.7685 | Intermediate Similarity | NPC40170 |
0.7685 | Intermediate Similarity | NPC235889 |
0.7679 | Intermediate Similarity | NPC71348 |
0.767 | Intermediate Similarity | NPC111015 |
0.7664 | Intermediate Similarity | NPC22388 |
0.7664 | Intermediate Similarity | NPC473424 |
0.7647 | Intermediate Similarity | NPC99380 |
0.7642 | Intermediate Similarity | NPC474720 |
0.7642 | Intermediate Similarity | NPC476274 |
0.7642 | Intermediate Similarity | NPC15390 |
0.7632 | Intermediate Similarity | NPC270958 |
0.7624 | Intermediate Similarity | NPC275740 |
0.7624 | Intermediate Similarity | NPC86319 |
0.7624 | Intermediate Similarity | NPC474679 |
0.7619 | Intermediate Similarity | NPC69385 |
0.7619 | Intermediate Similarity | NPC87090 |
0.7615 | Intermediate Similarity | NPC181265 |
0.7615 | Intermediate Similarity | NPC470267 |
0.7611 | Intermediate Similarity | NPC202889 |
0.7593 | Intermediate Similarity | NPC311612 |
0.7589 | Intermediate Similarity | NPC174471 |
0.7589 | Intermediate Similarity | NPC475937 |
0.7589 | Intermediate Similarity | NPC474871 |
0.7589 | Intermediate Similarity | NPC96739 |
0.7589 | Intermediate Similarity | NPC260786 |
0.7589 | Intermediate Similarity | NPC43775 |
0.7589 | Intermediate Similarity | NPC158523 |
0.757 | Intermediate Similarity | NPC476223 |
0.757 | Intermediate Similarity | NPC477356 |
0.757 | Intermediate Similarity | NPC224720 |
0.757 | Intermediate Similarity | NPC476240 |
0.7568 | Intermediate Similarity | NPC475941 |
0.7568 | Intermediate Similarity | NPC214644 |
0.7568 | Intermediate Similarity | NPC474901 |
0.7549 | Intermediate Similarity | NPC477711 |
0.7549 | Intermediate Similarity | NPC470832 |
0.7547 | Intermediate Similarity | NPC147954 |
0.7547 | Intermediate Similarity | NPC477355 |
0.7545 | Intermediate Similarity | NPC185 |
0.7544 | Intermediate Similarity | NPC136922 |
0.7525 | Intermediate Similarity | NPC477710 |
0.7525 | Intermediate Similarity | NPC475001 |
0.7525 | Intermediate Similarity | NPC328539 |
0.7525 | Intermediate Similarity | NPC471941 |
0.7525 | Intermediate Similarity | NPC185059 |
0.7525 | Intermediate Similarity | NPC131470 |
0.7525 | Intermediate Similarity | NPC143767 |
0.7524 | Intermediate Similarity | NPC471039 |
0.7524 | Intermediate Similarity | NPC328162 |
0.7524 | Intermediate Similarity | NPC49371 |
0.7524 | Intermediate Similarity | NPC249954 |
0.7524 | Intermediate Similarity | NPC305483 |
0.7524 | Intermediate Similarity | NPC96859 |
0.7523 | Intermediate Similarity | NPC29705 |
0.7522 | Intermediate Similarity | NPC170212 |
0.7522 | Intermediate Similarity | NPC265499 |
0.7522 | Intermediate Similarity | NPC17138 |
0.7522 | Intermediate Similarity | NPC475391 |
0.7522 | Intermediate Similarity | NPC221511 |
0.7522 | Intermediate Similarity | NPC151216 |
0.7522 | Intermediate Similarity | NPC215643 |
0.7522 | Intermediate Similarity | NPC89227 |
0.7522 | Intermediate Similarity | NPC101825 |
0.75 | Intermediate Similarity | NPC87351 |
0.75 | Intermediate Similarity | NPC261125 |
0.75 | Intermediate Similarity | NPC477439 |
0.75 | Intermediate Similarity | NPC235077 |
0.75 | Intermediate Similarity | NPC181195 |
0.75 | Intermediate Similarity | NPC245972 |
0.75 | Intermediate Similarity | NPC197428 |
0.75 | Intermediate Similarity | NPC308351 |
0.75 | Intermediate Similarity | NPC196485 |
0.75 | Intermediate Similarity | NPC308726 |
0.75 | Intermediate Similarity | NPC271266 |
0.75 | Intermediate Similarity | NPC118405 |
0.75 | Intermediate Similarity | NPC477915 |
0.75 | Intermediate Similarity | NPC153036 |
0.75 | Intermediate Similarity | NPC103527 |
0.75 | Intermediate Similarity | NPC471040 |
0.75 | Intermediate Similarity | NPC118638 |
0.75 | Intermediate Similarity | NPC119601 |
0.7478 | Intermediate Similarity | NPC298278 |
0.7477 | Intermediate Similarity | NPC35751 |
0.7477 | Intermediate Similarity | NPC217201 |
0.7477 | Intermediate Similarity | NPC46761 |
0.7477 | Intermediate Similarity | NPC94529 |
0.7477 | Intermediate Similarity | NPC83709 |
0.7477 | Intermediate Similarity | NPC154072 |
0.7475 | Intermediate Similarity | NPC251170 |
0.7456 | Intermediate Similarity | NPC108721 |
0.7456 | Intermediate Similarity | NPC474937 |
0.7456 | Intermediate Similarity | NPC71889 |
0.7456 | Intermediate Similarity | NPC194100 |
0.7456 | Intermediate Similarity | NPC73300 |
0.7455 | Intermediate Similarity | NPC60681 |
0.7455 | Intermediate Similarity | NPC97202 |
0.7455 | Intermediate Similarity | NPC150531 |
0.7455 | Intermediate Similarity | NPC49958 |
0.7455 | Intermediate Similarity | NPC260268 |
0.7455 | Intermediate Similarity | NPC476027 |
0.7455 | Intermediate Similarity | NPC214264 |
0.7455 | Intermediate Similarity | NPC319077 |
0.7455 | Intermediate Similarity | NPC50692 |
0.7455 | Intermediate Similarity | NPC48733 |
0.7455 | Intermediate Similarity | NPC296945 |
0.7455 | Intermediate Similarity | NPC302607 |
0.7455 | Intermediate Similarity | NPC85829 |
0.7455 | Intermediate Similarity | NPC171137 |
0.7455 | Intermediate Similarity | NPC152695 |
0.7455 | Intermediate Similarity | NPC202167 |
0.7453 | Intermediate Similarity | NPC190554 |
0.7451 | Intermediate Similarity | NPC326627 |
0.7451 | Intermediate Similarity | NPC477943 |
0.7451 | Intermediate Similarity | NPC474245 |
0.7451 | Intermediate Similarity | NPC310010 |
0.7451 | Intermediate Similarity | NPC76879 |
0.7451 | Intermediate Similarity | NPC472983 |
0.7434 | Intermediate Similarity | NPC231589 |
0.7434 | Intermediate Similarity | NPC118860 |
0.7434 | Intermediate Similarity | NPC207689 |
0.7434 | Intermediate Similarity | NPC214797 |
0.7431 | Intermediate Similarity | NPC111323 |
0.7431 | Intermediate Similarity | NPC191892 |
0.7429 | Intermediate Similarity | NPC259286 |
0.7429 | Intermediate Similarity | NPC477438 |
0.7429 | Intermediate Similarity | NPC477437 |
0.7429 | Intermediate Similarity | NPC470016 |
0.7429 | Intermediate Similarity | NPC317586 |
0.7414 | Intermediate Similarity | NPC471854 |
0.7411 | Intermediate Similarity | NPC163004 |
0.7411 | Intermediate Similarity | NPC304495 |
0.7411 | Intermediate Similarity | NPC258543 |
0.7411 | Intermediate Similarity | NPC11710 |
0.7411 | Intermediate Similarity | NPC470257 |
0.7411 | Intermediate Similarity | NPC241927 |
0.7407 | Intermediate Similarity | NPC163372 |
0.7407 | Intermediate Similarity | NPC302537 |
0.7404 | Intermediate Similarity | NPC202824 |
0.7404 | Intermediate Similarity | NPC125180 |
0.7404 | Intermediate Similarity | NPC477435 |
0.7404 | Intermediate Similarity | NPC477361 |
0.7404 | Intermediate Similarity | NPC250575 |
0.7404 | Intermediate Similarity | NPC477436 |
0.7404 | Intermediate Similarity | NPC475255 |
0.7404 | Intermediate Similarity | NPC12722 |
0.7404 | Intermediate Similarity | NPC69454 |
0.74 | Intermediate Similarity | NPC470574 |
0.7391 | Intermediate Similarity | NPC474872 |
0.7391 | Intermediate Similarity | NPC238667 |
0.7387 | Intermediate Similarity | NPC43285 |
0.7387 | Intermediate Similarity | NPC83744 |
0.7387 | Intermediate Similarity | NPC58370 |
0.7387 | Intermediate Similarity | NPC475060 |
0.7387 | Intermediate Similarity | NPC475294 |
0.7387 | Intermediate Similarity | NPC220974 |
0.7387 | Intermediate Similarity | NPC220229 |
0.7379 | Intermediate Similarity | NPC2946 |
0.7379 | Intermediate Similarity | NPC126993 |
0.7368 | Intermediate Similarity | NPC100267 |
0.7368 | Intermediate Similarity | NPC147180 |
0.7368 | Intermediate Similarity | NPC215481 |
0.7368 | Intermediate Similarity | NPC475970 |
0.7368 | Intermediate Similarity | NPC475524 |
0.7368 | Intermediate Similarity | NPC264634 |
0.7368 | Intermediate Similarity | NPC207251 |
0.7368 | Intermediate Similarity | NPC170487 |
0.7364 | Intermediate Similarity | NPC75531 |
0.7364 | Intermediate Similarity | NPC13385 |
0.7364 | Intermediate Similarity | NPC149124 |
0.7364 | Intermediate Similarity | NPC209502 |
0.7364 | Intermediate Similarity | NPC204833 |
0.7358 | Intermediate Similarity | NPC477354 |
0.7353 | Intermediate Similarity | NPC471722 |
0.735 | Intermediate Similarity | NPC171905 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC470839 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.8302 | Intermediate Similarity | NPD6899 | Approved |
0.8302 | Intermediate Similarity | NPD6881 | Approved |
0.8286 | Intermediate Similarity | NPD6402 | Approved |
0.8286 | Intermediate Similarity | NPD5739 | Approved |
0.8286 | Intermediate Similarity | NPD6675 | Approved |
0.8286 | Intermediate Similarity | NPD7128 | Approved |
0.8208 | Intermediate Similarity | NPD5697 | Approved |
0.8155 | Intermediate Similarity | NPD4696 | Approved |
0.8155 | Intermediate Similarity | NPD5286 | Approved |
0.8155 | Intermediate Similarity | NPD5285 | Approved |
0.8148 | Intermediate Similarity | NPD6883 | Approved |
0.8148 | Intermediate Similarity | NPD7102 | Approved |
0.8148 | Intermediate Similarity | NPD7290 | Approved |
0.8137 | Intermediate Similarity | NPD4755 | Approved |
0.8131 | Intermediate Similarity | NPD7320 | Approved |
0.8131 | Intermediate Similarity | NPD6011 | Approved |
0.8077 | Intermediate Similarity | NPD5223 | Approved |
0.8073 | Intermediate Similarity | NPD8130 | Phase 1 |
0.8073 | Intermediate Similarity | NPD6869 | Approved |
0.8073 | Intermediate Similarity | NPD6847 | Approved |
0.8073 | Intermediate Similarity | NPD6650 | Approved |
0.8073 | Intermediate Similarity | NPD6649 | Approved |
0.8073 | Intermediate Similarity | NPD6617 | Approved |
0.8056 | Intermediate Similarity | NPD6012 | Approved |
0.8056 | Intermediate Similarity | NPD6373 | Approved |
0.8056 | Intermediate Similarity | NPD6372 | Approved |
0.8056 | Intermediate Similarity | NPD6014 | Approved |
0.8056 | Intermediate Similarity | NPD6013 | Approved |
0.8037 | Intermediate Similarity | NPD5701 | Approved |
0.8 | Intermediate Similarity | NPD5226 | Approved |
0.8 | Intermediate Similarity | NPD8297 | Approved |
0.8 | Intermediate Similarity | NPD5211 | Phase 2 |
0.8 | Intermediate Similarity | NPD6882 | Approved |
0.8 | Intermediate Similarity | NPD4633 | Approved |
0.8 | Intermediate Similarity | NPD5225 | Approved |
0.8 | Intermediate Similarity | NPD5224 | Approved |
0.7981 | Intermediate Similarity | NPD4700 | Approved |
0.7925 | Intermediate Similarity | NPD5175 | Approved |
0.7925 | Intermediate Similarity | NPD5174 | Approved |
0.7909 | Intermediate Similarity | NPD6401 | Clinical (unspecified phase) |
0.7864 | Intermediate Similarity | NPD4697 | Phase 3 |
0.785 | Intermediate Similarity | NPD5141 | Approved |
0.7757 | Intermediate Similarity | NPD4754 | Approved |
0.7692 | Intermediate Similarity | NPD5220 | Clinical (unspecified phase) |
0.7692 | Intermediate Similarity | NPD5222 | Approved |
0.7692 | Intermediate Similarity | NPD5221 | Approved |
0.7652 | Intermediate Similarity | NPD6335 | Approved |
0.7647 | Intermediate Similarity | NPD6079 | Approved |
0.7636 | Intermediate Similarity | NPD4729 | Approved |
0.7636 | Intermediate Similarity | NPD4730 | Approved |
0.7636 | Intermediate Similarity | NPD5128 | Approved |
0.7632 | Intermediate Similarity | NPD6274 | Approved |
0.7624 | Intermediate Similarity | NPD5328 | Approved |
0.7619 | Intermediate Similarity | NPD6083 | Phase 2 |
0.7619 | Intermediate Similarity | NPD6084 | Phase 2 |
0.7619 | Intermediate Similarity | NPD5173 | Approved |
0.7615 | Intermediate Similarity | NPD4767 | Approved |
0.7615 | Intermediate Similarity | NPD4768 | Approved |
0.7596 | Intermediate Similarity | NPD5695 | Phase 3 |
0.7586 | Intermediate Similarity | NPD7101 | Approved |
0.7586 | Intermediate Similarity | NPD7100 | Approved |
0.7573 | Intermediate Similarity | NPD4202 | Approved |
0.7565 | Intermediate Similarity | NPD6317 | Approved |
0.7521 | Intermediate Similarity | NPD6054 | Approved |
0.75 | Intermediate Similarity | NPD5135 | Approved |
0.75 | Intermediate Similarity | NPD5134 | Clinical (unspecified phase) |
0.75 | Intermediate Similarity | NPD6313 | Approved |
0.75 | Intermediate Similarity | NPD5250 | Approved |
0.75 | Intermediate Similarity | NPD5251 | Approved |
0.75 | Intermediate Similarity | NPD5169 | Approved |
0.75 | Intermediate Similarity | NPD5249 | Phase 3 |
0.75 | Intermediate Similarity | NPD6314 | Approved |
0.75 | Intermediate Similarity | NPD5248 | Approved |
0.75 | Intermediate Similarity | NPD5247 | Approved |
0.75 | Intermediate Similarity | NPD4634 | Approved |
0.7456 | Intermediate Similarity | NPD4632 | Approved |
0.7451 | Intermediate Similarity | NPD4753 | Phase 2 |
0.7434 | Intermediate Similarity | NPD5215 | Approved |
0.7434 | Intermediate Similarity | NPD5127 | Approved |
0.7434 | Intermediate Similarity | NPD5216 | Approved |
0.7434 | Intermediate Similarity | NPD5217 | Approved |
0.7414 | Intermediate Similarity | NPD6009 | Approved |
0.74 | Intermediate Similarity | NPD5329 | Approved |
0.7395 | Intermediate Similarity | NPD6370 | Approved |
0.7383 | Intermediate Similarity | NPD5696 | Approved |
0.7373 | Intermediate Similarity | NPD6319 | Approved |
0.7373 | Intermediate Similarity | NPD6059 | Approved |
0.7333 | Intermediate Similarity | NPD7604 | Phase 2 |
0.7327 | Intermediate Similarity | NPD5690 | Phase 2 |
0.7311 | Intermediate Similarity | NPD5983 | Phase 2 |
0.7311 | Intermediate Similarity | NPD6909 | Approved |
0.7311 | Intermediate Similarity | NPD6015 | Approved |
0.7311 | Intermediate Similarity | NPD6908 | Approved |
0.7311 | Intermediate Similarity | NPD6016 | Approved |
0.73 | Intermediate Similarity | NPD4197 | Approved |
0.7282 | Intermediate Similarity | NPD6080 | Approved |
0.7282 | Intermediate Similarity | NPD6673 | Approved |
0.7282 | Intermediate Similarity | NPD6904 | Approved |
0.7273 | Intermediate Similarity | NPD7492 | Approved |
0.7264 | Intermediate Similarity | NPD5210 | Approved |
0.7264 | Intermediate Similarity | NPD4629 | Approved |
0.725 | Intermediate Similarity | NPD5988 | Approved |
0.7241 | Intermediate Similarity | NPD5167 | Approved |
0.7213 | Intermediate Similarity | NPD6336 | Discontinued |
0.7213 | Intermediate Similarity | NPD6616 | Approved |
0.7184 | Intermediate Similarity | NPD6672 | Approved |
0.7184 | Intermediate Similarity | NPD5737 | Approved |
0.7179 | Intermediate Similarity | NPD6868 | Approved |
0.7167 | Intermediate Similarity | NPD6291 | Clinical (unspecified phase) |
0.7157 | Intermediate Similarity | NPD4694 | Approved |
0.7157 | Intermediate Similarity | NPD5280 | Approved |
0.7157 | Intermediate Similarity | NPD5279 | Phase 3 |
0.7157 | Intermediate Similarity | NPD3618 | Phase 1 |
0.7154 | Intermediate Similarity | NPD7078 | Approved |
0.7143 | Intermediate Similarity | NPD6050 | Approved |
0.7143 | Intermediate Similarity | NPD6008 | Approved |
0.7129 | Intermediate Similarity | NPD3665 | Phase 1 |
0.7129 | Intermediate Similarity | NPD3666 | Approved |
0.7129 | Intermediate Similarity | NPD3133 | Approved |
0.71 | Intermediate Similarity | NPD4221 | Approved |
0.71 | Intermediate Similarity | NPD4223 | Phase 3 |
0.7097 | Intermediate Similarity | NPD7736 | Approved |
0.7075 | Intermediate Similarity | NPD6399 | Phase 3 |
0.7048 | Intermediate Similarity | NPD5692 | Phase 3 |
0.7018 | Intermediate Similarity | NPD5168 | Approved |
0.7016 | Intermediate Similarity | NPD8293 | Discontinued |
0.699 | Remote Similarity | NPD5330 | Approved |
0.699 | Remote Similarity | NPD7334 | Approved |
0.699 | Remote Similarity | NPD6684 | Approved |
0.699 | Remote Similarity | NPD6409 | Approved |
0.699 | Remote Similarity | NPD6098 | Approved |
0.699 | Remote Similarity | NPD7146 | Approved |
0.699 | Remote Similarity | NPD7521 | Approved |
0.699 | Remote Similarity | NPD3574 | Clinical (unspecified phase) |
0.6981 | Remote Similarity | NPD5693 | Phase 1 |
0.6981 | Remote Similarity | NPD5694 | Approved |
0.6961 | Remote Similarity | NPD4786 | Approved |
0.696 | Remote Similarity | NPD6033 | Approved |
0.6944 | Remote Similarity | NPD6356 | Clinical (unspecified phase) |
0.6863 | Remote Similarity | NPD4788 | Approved |
0.6857 | Remote Similarity | NPD7513 | Clinical (unspecified phase) |
0.6857 | Remote Similarity | NPD6903 | Approved |
0.6852 | Remote Similarity | NPD7748 | Approved |
0.6827 | Remote Similarity | NPD4138 | Approved |
0.6827 | Remote Similarity | NPD4689 | Approved |
0.6827 | Remote Similarity | NPD4690 | Approved |
0.6827 | Remote Similarity | NPD4693 | Phase 3 |
0.6827 | Remote Similarity | NPD5205 | Approved |
0.6827 | Remote Similarity | NPD4688 | Approved |
0.6822 | Remote Similarity | NPD5281 | Approved |
0.6822 | Remote Similarity | NPD5284 | Approved |
0.6818 | Remote Similarity | NPD7902 | Approved |
0.68 | Remote Similarity | NPD7507 | Approved |
0.6765 | Remote Similarity | NPD3667 | Approved |
0.6765 | Remote Similarity | NPD6435 | Approved |
0.6757 | Remote Similarity | NPD7638 | Approved |
0.6733 | Remote Similarity | NPD4695 | Discontinued |
0.6733 | Remote Similarity | NPD7525 | Registered |
0.6696 | Remote Similarity | NPD7640 | Approved |
0.6696 | Remote Similarity | NPD7639 | Approved |
0.6667 | Remote Similarity | NPD8034 | Phase 2 |
0.6667 | Remote Similarity | NPD8035 | Phase 2 |
0.6667 | Remote Similarity | NPD7515 | Phase 2 |
0.6641 | Remote Similarity | NPD7319 | Approved |
0.6639 | Remote Similarity | NPD6053 | Discontinued |
0.6638 | Remote Similarity | NPD6412 | Phase 2 |
0.6636 | Remote Similarity | NPD5654 | Approved |
0.6634 | Remote Similarity | NPD4195 | Approved |
0.6606 | Remote Similarity | NPD5133 | Approved |
0.6604 | Remote Similarity | NPD3573 | Approved |
0.6579 | Remote Similarity | NPD5091 | Approved |
0.6574 | Remote Similarity | NPD4096 | Approved |
0.6569 | Remote Similarity | NPD5368 | Approved |
0.6557 | Remote Similarity | NPD7115 | Discovery |
0.6545 | Remote Similarity | NPD5282 | Discontinued |
0.6545 | Remote Similarity | NPD7900 | Approved |
0.6545 | Remote Similarity | NPD6001 | Approved |
0.6545 | Remote Similarity | NPD7901 | Clinical (unspecified phase) |
0.6542 | Remote Similarity | NPD5208 | Approved |
0.6535 | Remote Similarity | NPD3617 | Approved |
0.6518 | Remote Similarity | NPD5959 | Approved |
0.6496 | Remote Similarity | NPD6614 | Approved |
0.6476 | Remote Similarity | NPD3668 | Phase 3 |
0.6471 | Remote Similarity | NPD6371 | Approved |
0.6422 | Remote Similarity | NPD5207 | Approved |
0.6422 | Remote Similarity | NPD5785 | Approved |
0.6415 | Remote Similarity | NPD7520 | Clinical (unspecified phase) |
0.6389 | Remote Similarity | NPD4518 | Approved |
0.637 | Remote Similarity | NPD6334 | Approved |
0.637 | Remote Similarity | NPD6333 | Approved |
0.6346 | Remote Similarity | NPD4692 | Approved |
0.6346 | Remote Similarity | NPD4139 | Approved |
0.6346 | Remote Similarity | NPD5369 | Approved |
0.6339 | Remote Similarity | NPD1698 | Clinical (unspecified phase) |
0.632 | Remote Similarity | NPD4522 | Approved |
0.6286 | Remote Similarity | NPD4752 | Clinical (unspecified phase) |
0.6262 | Remote Similarity | NPD1696 | Phase 3 |
0.6262 | Remote Similarity | NPD5363 | Approved |
0.625 | Remote Similarity | NPD8259 | Clinical (unspecified phase) |
0.625 | Remote Similarity | NPD8328 | Phase 3 |
PubChem CID   | 16736857 |
ChEMBL   | CHEMBL226247 |
ZINC   |
Molecular Weight:   | 488.35 |
ALogP:   | 1.4246 |
MLogP:   | 4.21 |
XLogP:   | 4.65 |
# Rotatable Bonds:   | 13 |
Polar Surface Area:   | 83.83 |
# H-Bond Aceptor:   | 5 |
# H-Bond Donor:   | 2 |
# Rings:   | 4 |
# Heavy Atoms:   | 35 |