Natural Product: NPC332382

Natural Product ID:  NPC332382
Common Name:   Metronidazole
IUPAC Name:   2-(2-methyl-5-nitroimidazol-1-yl)ethanol
Synonyms:   Acea; Anabact; BAY-5360; BAYER-5360; Drazifon; Elyzol; Flagyl; Flagyl 375; Flagyl Compak; Flagyl Er; Flagyl I.V. Rtu In Plastic Container; Flagyl-400; Flagyl-S; Metric 21; Metro Iv; Metrocream; Metrogel; Metrogel-Vaginal; Metrolotion; Metrolyl; Metromidol; Metronidazole; Metrosa; Metrotop; Neutratop; Noritate; Norzol; Protostat; Rosiced; Rozex; RP-8823; Satric; Vaginyl; Vandazole; Zadstat; Zidoval; Zyomet
Molecular Formula:   C6H9N3O3
Standard InCHIKey:  VAOCPAMSLUNLGC-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C6H9N3O3/c1-5-7-4-6(9(11)12)8(5)2-3-10/h4,10H,2-3H2,1H3
Canonical SMILES:  OCCn1c(C)ncc1N(=O)=O
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO13391 Streptomyces hygroscopicus Species Streptomycetaceae Bacteria PMID[24224794]

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT4993 Organism Prevotella disiens Prevotella disiens MIC90 = 2 ug/ml 18811205
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC <= 0.06 ug/ml 17883259
NPT4429 Organism Prevotella loescheii Prevotella loescheii MIC90 = 2 ug/ml 15387639
NPT2 Others Unspecified Potency = 14.1 nM 15387639
NPT19 Organism Escherichia coli Escherichia coli MIC > 500000 nM PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 600000 nM PubChem BioAssay data set
NPT19 Organism Escherichia coli Escherichia coli MIC = 100000 nM PubChem BioAssay data set
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 2746 nM PubChem BioAssay data set
NPT992 Organism Entamoeba histolytica Entamoeba histolytica EC50 = 2000 nM 20329738
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC90 = 0.5 ug/ml 20329738
NPT2 Others Unspecified MBC = 6.25 ug/ml 12662103
NPT2 Others Unspecified MIC90 = 1 ug/ml 15043423
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC90 > 16 ug/ml 25913865
NPT4824 Organism Prevotella bivia Prevotella bivia MIC90 = 8 ug/ml 23145884
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC50 = 0.5 ug/ml 23734701
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC50 = 0.25 ug/ml 23734701
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity = 0 % 23734701
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 0.04 ug/ml 23713692
NPT4820 Organism Peptostreptococcus micros Parvimonas micra Activity = 88 % 9834146
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 5.4 ug/ml 12398531
NPT4429 Organism Prevotella loescheii Prevotella loescheii MIC = 0.062 ug/ml 1791472
NPT4993 Organism Prevotella disiens Prevotella disiens MIC = 1 ug/ml PubChem BioAssay data set
NPT4993 Organism Prevotella disiens Prevotella disiens MIC50 = 0.5 ug/ml 26341134
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 26343828
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 18.4 mm 22749392
NPT2 Others Unspecified IC50 = 770 nM 23547843
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC50 = 8 ug/ml 12880316
NPT2 Others Unspecified Activity = 46 % 12880316
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 6 mm 23215246
NPT2 Others Unspecified Activity = 46 % 12762798
NPT2 Others Unspecified MIC50 = 1 ug/ml 16441079
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC50 = 1 ug/ml 19646881
NPT2 Others Unspecified MIC90 = 4 ug/ml 17346076
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Ratio = 15 23006147
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 2 ug/ml 23282042
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 292800 nM 17877337
NPT4803 Organism Dialister propionicifaciens Dialister propionicifaciens Activity <= 8 ug/ml 15911254
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 0.04 ug/ml 10869203
NPT4823 Organism Prevotella buccae Prevotella buccae MIC50 = 0.5 ug/ml 24328283
NPT4824 Organism Prevotella bivia Prevotella bivia MIC50 = 0.5 ug/ml 24328283
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 11421731
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 11421731
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum Activity = 0 % 11421731
NPT2 Others Unspecified MIC = 4 ug/ml 25798528
NPT2 Others Unspecified MIC = 1 ug/ml 25798528
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 25798528
NPT2 Others Unspecified MIC = 4 ug/ml 25782063
NPT2 Others Unspecified MIC = 2 ug/ml 25782063
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 25782063
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 4 ug/ml 25798528
NPT2 Others Unspecified AC50 7943.3 nM 11754615
NPT282 Individual Protein MAP kinase ERK2 Homo sapiens Potency = 15848.9 nM 2089123
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 0.5 ug/ml 11809056
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC <= 0.125 ug/ml 24467317
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC = 0.25 ug/ml DrugMatrix in vitro pharmacology data
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Inhibition = 100 % DrugMatrix in vitro pharmacology data
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC90 = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.5 ug/ml DrugMatrix in vivo data: Biochemistry
NPT2 Others Unspecified MIC50 = 0.5 ug/ml DrugMatrix in vivo data: Biochemistry
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC90 = 2 ug/ml DrugMatrix in vivo data: Hematology
NPT2 Others Unspecified MIC50 = 1 ug/ml 27015610
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 720 nM 19105653
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 2 ug/ml 10869195
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 4 ug/ml 10869195
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml 10869195
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 4 ug/ml 20462233
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 2 ug/ml 20462233
NPT1359 Organism Clostridium perfringens Clostridium perfringens Activity = 0 % 23131412
NPT6492 Organism Clostridium aminovalericum Clostridium aminovalericum Activity = 0 % 11325233
NPT4817 Organism Finegoldia magna Finegoldia magna MIC = 0.5 ug/ml 19743809
NPT4824 Organism Prevotella bivia Prevotella bivia MIC50 = 1 ug/ml 19743809
NPT4552 Organism Bacteroides sp. Bacteroides sp. MIC90 = 2 ug/ml 17269824
NPT4552 Organism Bacteroides sp. Bacteroides sp. MIC50 = 0.5 ug/ml 17269824
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC <= 0.125 ug/ml 19743809
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 0.33 ug/ml 26483137
NPT2 Others Unspecified MIC90 = 1 ug/ml 26483137
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 1 ug/ml 15679321
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 26186257
NPT2 Others Unspecified Activity = 46 % 18341287
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC = 0.5 ug/ml 10579872
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv Activity = 36 % 17190448
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC > 16 ug/ml 20058933
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis Activity = 100 % 18419154
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 1 ug/ml 3210015
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.25 ug/ml 3210015
NPT2 Others Unspecified MIC = 0.5 ug/ml 9307570
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 1 ug/ml 23558238
NPT2 Others Unspecified MIC = 1 ug/ml 23558238
NPT2 Others Unspecified MIC90 > 64 ug/ml 26562066
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC90 <= 0.12 ug/ml 25978520
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 1 ug/ml 8573592
NPT4592 Cell Line CHO-AA8 Cricetulus griseus IC50 = 23000000 nM 12444709
NPT2 Others Unspecified MIC = 0.12 ug/ml 25600409
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.5 ug/ml 24972328
NPT2 Others Unspecified Potency 6113.1 nM 23869482
NPT2 Others Unspecified MIC50 = 2 ug/ml 11374943
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC = 0.12 ug/ml 20958014
NPT2 Others Unspecified MIC90 = 1 ug/ml 21115251
NPT4987 Organism Clostridium butyricum Clostridium butyricum MIC90 = 1 ug/ml 21115251
NPT2 Others Unspecified IC50 = 720 nM 20932762
NPT4824 Organism Prevotella bivia Prevotella bivia MIC50 = 2 ug/ml 8201311
NPT2 Others Unspecified MIC > 4 ug/ml 11520225
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC = 1 ug/ml 10514320
NPT4987 Organism Clostridium butyricum Clostridium butyricum MIC <= 0.125 ug/ml 15730262
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC90 = 0.5 ug/ml 8699186
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC90 = 0.5 ug/ml 25927480
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 22691179
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii MIC90 > 128 ug/ml 19161316
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC50 = 0.5 ug/ml 19943620
NPT2 Others Unspecified MIC90 = 1 ug/ml 11277744
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 2 ug/ml 23190013
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml 23190013
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 4 ug/ml 23190013
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 32 ug/ml 23190013
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 2 ug/ml PubChem BioAssay data set
NPT4992 Organism Prevotella corporis Prevotella corporis MIC90 = 0.25 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC90 = 0.5 ug/ml PubChem BioAssay data set
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC90 = 0.5 ug/ml PubChem BioAssay data set
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii Activity = 46 % 22472691
NPT4804 Organism Dialister invisus Dialister invisus Activity <= 8 ug/ml 16562839
NPT6240 Organism Clostridium sphenoides Clostridium sphenoides MIC50 = 0.125 ug/ml 12762799
NPT6491 Organism Clostridium malenominatum Clostridium malenominatum MIC90 = 0.25 ug/ml 22409377
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC <= 0.125 ug/ml 24479418
NPT2 Others Unspecified Ratio IC50 > 55.55 PubChem BioAssay data set
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum Activity = 5.6 % 18298075
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC90 = 1 ug/ml 9599272
NPT65 Cell Line HepG2 Homo sapiens Activity > 200 ug/ml 1360492
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Inhibition = 100 % 18053715
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC50 <= 0.12 ug/ml 17887724
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 17475486
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. Activity = 34.1 % 25066952
NPT2 Others Unspecified MIC = 0.12 ug/ml 25008455
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 0.5 ug/ml 20949916
NPT4982 Organism Collinsella aerofaciens Collinsella aerofaciens MIC50 = 0.5 ug/ml 17696332
NPT167 Organism Propionibacterium acnes Propionibacterium acnes Activity = 100 % 10.1007/s00044-013-0466-y
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC = 0.5 ug/ml PubChem BioAssay data set
NPT4835 Organism Clostridium tertium Clostridium tertium MIC50 = 0.25 ug/ml 15711537
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 100000 nM 18313304
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 5000 nM 17850214
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 0.5 ug/ml 17850214
NPT4836 Organism Eggerthella lenta Eggerthella lenta Activity = 46 % 17850214
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis ED50 = 11.5 mg/kg PubChem BioAssay data set
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 5 ug/ml PubChem BioAssay data set
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 21345685
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 4 ug/ml PubChem BioAssay data set
NPT4817 Organism Finegoldia magna Finegoldia magna MIC = 0.25 ug/ml PubChem BioAssay data set
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC = 0.13 ug/ml PubChem BioAssay data set
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 1 ug/ml PubChem BioAssay data set
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC = 0.25 ug/ml 23398362
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1460 nM 23398362
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1800 nM 23398362
NPT2 Others Unspecified MIC90 = 1 ug/ml 23398362
NPT4982 Organism Collinsella aerofaciens Collinsella aerofaciens MIC90 = 1 ug/ml 23398362
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.5 ug/ml 23398362
NPT2 Others Unspecified MIC = 1460 nM 23398362
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 1 ug/ml 23398362
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 0.5 ug/ml 23398362
NPT451 Organism Helicobacter pylori Helicobacter pylori Inhibition = 81.9 % 23398362
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC90 = 1 ug/ml 23398362
NPT83 Cell Line MCF7 Homo sapiens IC50 > 250000 nM PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 16 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 9 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 20 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 13 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 14 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 10 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 15 nmol/min PubChem BioAssay data set
NPT4824 Organism Prevotella bivia Prevotella bivia MIC90 = 4 ug/ml PubChem BioAssay data set
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1800 nM PubChem BioAssay data set
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1840 nM 16499327
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC90 = 0.5 ug/ml 26090896
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 32 ug/ml 26090896
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 8 ug/ml 26090896
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 16 ug/ml 26090896
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 16 ug/ml 12608862
NPT586 Organism Giardia Giardia Potency 4599.7 nM 25781655
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC90 = 2 ug/ml 24095094
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 2 ug/ml 12444688
NPT4801 Organism Dialister micraerophilus Dialister micraerophilus MIC50 = 2 ug/ml 24332631
NPT17 Organism Staphylococcus epidermidis Staphylococcus epidermidis MIC > 100 ug/ml 22691179
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 8 ug/ml 18053716
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml 10075772
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 1 ug/ml 10924177
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 2 ug/ml 19928902
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC > 0.03 ug/ml 24893224
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1500 nM 15332861
NPT1216 Cell Line FaDu Homo sapiens Activity > 200 ug/ml 24033131
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC90 = 0.5 ug/ml 22197393
NPT2 Others Unspecified MIC50 = 1 ug/ml 22197393
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC90 = 2 ug/ml 22197393
NPT4993 Organism Prevotella disiens Prevotella disiens MIC90 = 2 ug/ml 22197393
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC50 = 1 ug/ml 15217273
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC = 0.03 ug/ml 16038562
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 230 nM 20420415
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1220 nM 20420415
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC = 0.016 ug/ml 20550123
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC50 = 0.5 ug/ml 25871540
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 6000 nM 25871540
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 13000 nM 7931367
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 2 ug/ml 7931367
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC90 = 2 ug/ml 10217724
NPT2 Others Unspecified MIC = 0.016 ug/ml 24582402
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 4400 nM 24467317
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 22276775
NPT4983 Organism Eubacterium limosum Eubacterium limosum MIC90 = 0.5 ug/ml 18258441
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC90 = 0.5 ug/ml 12502331
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 9599261
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC90 = 16 ug/ml 17253840
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 1 ug/ml 20598551
NPT2 Others Unspecified MIC = 0.12 ug/ml 12036352
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC > 100 ug/ml 22329646
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC < 0.8 ug/ml 22329646
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC = 1.5 ug/ml 9461661
NPT2 Others Unspecified MIC = 1 ug/ml 16562846
NPT2 Others Unspecified GI = 100 % 10425118
NPT4801 Organism Dialister micraerophilus Dialister micraerophilus MIC = 1 ug/ml 17125224
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC > 0.5 ug/ml 17125222
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 24128115
NPT6240 Organism Clostridium sphenoides Clostridium sphenoides MIC90 = 4 ug/ml 23376010
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC90 = 4 ug/ml 23376010
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 1 ug/ml 23376010
NPT2645 Organism Giardia intestinalis Giardia intestinalis EC50 = 44668.36 nM 1431934
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus Activity = 100 % 20961068
NPT2 Others Unspecified MIC = 0.12 ug/ml 19344127
NPT2 Others Unspecified AC50 316.2 nM 22283451
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 236 nM 23368966
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1226 nM 17190450
NPT4830 Organism Actinomyces israelii Actinomyces israelii MIC90 > 32 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC90 > 32 ug/ml PubChem BioAssay data set
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC50 = 1 ug/ml PubChem BioAssay data set
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC50 = 1 ug/ml PubChem BioAssay data set
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC50 <= 0.125 ug/ml 19845338
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 1 ug/ml 20163893
NPT2 Others Unspecified MIC = 0.25 ug/ml 20163893
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 62480 nM 20521771
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC50 = 0.125 ug/ml 25659770
NPT10 Individual Protein Geminin Homo sapiens Potency 631 nM 25659770
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 4 ug/ml 19368377
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 12502308
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC50 = 0.5 ug/ml 24195447
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 24195447
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC90 = 1 ug/ml 22583079
NPT4993 Organism Prevotella disiens Prevotella disiens MIC = 0.25 ug/ml 17542572
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC = 0.25 ug/ml 17542572
NPT2 Others Unspecified MIC50 = 0.5 ug/ml PubChem BioAssay data set
NPT4983 Organism Eubacterium limosum Eubacterium limosum MIC50 = 0.5 ug/ml PubChem BioAssay data set
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 32 ug/ml PubChem BioAssay data set
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC <= 0.016 ug/ml 24195447
NPT2 Others Unspecified MIC <= 0.016 ug/ml 24295087
NPT6283 Organism Porphyromonas levii Porphyromonas levii MIC <= 0.016 ug/ml 24359303
NPT5913 Organism Prevotella denticola Prevotella denticola MIC <= 0.125 ug/ml 15332848
NPT20 Organism Candida albicans Candida albicans MIC > 32 ug/ml 26305406
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.5 ug/ml 26317881
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC50 = 2 ug/ml 26317881
NPT198 Individual Protein Vitamin D receptor Homo sapiens Potency 63095.7 nM 26317881
NPT6491 Organism Clostridium malenominatum Clostridium malenominatum MIC50 = 0.125 ug/ml 10924170
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.5 ug/ml 8277312
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC = 0.25 ug/ml 20815366
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 11600 nM 10650083
NPT2 Others Unspecified EC50 > 1000 ug/ml 20413315
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 2 ug/ml 24099304
NPT2 Others Unspecified MIC = 0.12 ug/ml 15217273
NPT2 Others Unspecified Potency 4727.7 nM 22071302
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 6800 nM 16933872
NPT4835 Organism Clostridium tertium Clostridium tertium MIC90 = 4 ug/ml 20491501
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC <= 0.125 ug/ml 20491501
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium Activity = 8.36 26123643
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 14 mm 17323995
NPT4835 Organism Clostridium tertium Clostridium tertium Activity = 64 % 19056281
NPT2 Others Unspecified MIC50 = 16 ug/ml 16408090
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity = 0 % 16408090
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 1920 nM 16408090
NPT2 Others Unspecified AC50 39810.7 nM 18494522
NPT2 Others Unspecified MIC90 = 4 ug/ml 22705001
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 580 nM 11325246
NPT4077 Organism Escherichia coli DH5[alpha] Escherichia coli DH5[alpha] GI = 6.64 % 22085418
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC <= 0.78 ug/ml 15043423
NPT2 Others Unspecified MIC = 0.13 ug/ml 21146414
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC90 = 1 ug/ml 21044847
NPT2645 Organism Giardia intestinalis Giardia intestinalis EC50 = 25703.96 nM 23815260
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC50 > 16 ug/ml 23964704
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.125 ug/ml 19691309
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.5 ug/ml 23067550
NPT4993 Organism Prevotella disiens Prevotella disiens MIC90 = 1 ug/ml 14611838
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 0.5 ug/ml 10891117
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 16 ug/ml 15780634
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii MIC90 = 128 ug/ml 16303302
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 32 nmol/min 17851083
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.2 ug/ml 18078756
NPT2 Others Unspecified IC50 > 1000 ug/ml 20038128
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.5 ug/ml 20138519
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.5 ug/ml 19879757
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 1 ug/ml 20718497
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 0.5 ug/ml 20718497
NPT4992 Organism Prevotella corporis Prevotella corporis MIC90 = 2 ug/ml 18505852
NPT5913 Organism Prevotella denticola Prevotella denticola MIC90 = 2 ug/ml 18505852
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.25 ug/ml 18378710
NPT165 Cell Line HeLa Homo sapiens EC50 > 1000 ug/ml 21044844
NPT4817 Organism Finegoldia magna Finegoldia magna MIC = 0.5 ug/ml 20937542
NPT2 Others Unspecified MIC = 0.12 ug/ml 19581465
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC50 = 1 ug/ml 16472241
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC90 = 1 ug/ml 16472241
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 11700 nM DrugMatrix in vitro pharmacology data
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 292000 nM DrugMatrix in vitro pharmacology data
NPT19 Organism Escherichia coli Escherichia coli MIC > 600000 nM DrugMatrix in vitro pharmacology data
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC <= 0.125 ug/ml DrugMatrix in vitro pharmacology data
NPT4817 Organism Finegoldia magna Finegoldia magna MIC = 0.25 ug/ml DrugMatrix in vitro pharmacology data
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Ratio = 8 22194678
NPT4992 Organism Prevotella corporis Prevotella corporis MIC90 = 1 ug/ml 21978838
NPT2 Others Unspecified MIC90 = 1 ug/ml 22197387
NPT1970 Cell Line THP-1 Homo sapiens IC50 > 500000 nM 22197389
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC90 = 8 ug/ml 22931300
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC50 = 0.125 ug/ml 23000294
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC50 <= 0.03 ug/ml 23062712
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris Activity = 0 % 22541068
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus Activity = 0 % 21920636
NPT4993 Organism Prevotella disiens Prevotella disiens MIC50 = 1 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC = 0.5 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.5 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 50 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 1 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.5 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT4834 Organism Clostridium septicum Clostridium septicum MIC50 = 8 ug/ml Open TG-GATES in vivo data: Hematology
NPT2 Others Unspecified MIC = 0.5 ug/ml Open TG-GATES in vivo data: Hematology
NPT65 Cell Line HepG2 Homo sapiens IC50 > 100000 nM Open TG-GATES in vivo data: Hematology
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC = 0.5 ug/ml Open TG-GATES in vivo data: Hematology
NPT451 Organism Helicobacter pylori Helicobacter pylori Inhibition = 20 % Open TG-GATES in vivo data: Hematology
NPT32 Organism Mus musculus Mus musculus LD50 = 3800 mg/kg Open TG-GATES in vivo data: Hematology
NPT2 Others Unspecified MIC = 2 ug/ml Open TG-GATES in vivo data: Hematology
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum Activity = 64 % Open TG-GATES in vivo data: Hematology
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC = 0.12 ug/ml Open TG-GATES in vivo data: Pathology
NPT29 Organism Rattus norvegicus Rattus norvegicus Inhibition = 66.3 % Open TG-GATES in vivo data: Hematology
NPT20 Organism Candida albicans Candida albicans IZ = 15 mm Open TG-GATES in vivo data: Organ Weight
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum Activity = 0 % DrugMatrix in vivo data: Biochemistry
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis MIC50 = 0.06 ug/ml DrugMatrix in vivo data: Biochemistry
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC50 = 0.06 ug/ml DrugMatrix in vivo data: Biochemistry
NPT6417 Organism Anaerococcus vaginalis Anaerococcus vaginalis MIC90 = 4 ug/ml DrugMatrix in vivo data: Hematology
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC90 = 128 ug/ml 10.1039/C3MD00251A
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 1 ug/ml 15646539
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 10 ug/ml 24972340
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.25 ug/ml 24878195
NPT5913 Organism Prevotella denticola Prevotella denticola MIC50 = 0.5 ug/ml 24967731
NPT4992 Organism Prevotella corporis Prevotella corporis MIC50 = 0.5 ug/ml 24967731
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity = 100 % 25050172
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 5360 nM 24953953
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 25238443
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 25221657
NPT4986 Organism Clostridium bifermentans Clostridium bifermentans MIC50 = 0.25 ug/ml 25264074
NPT2 Others Unspecified MIC = 2 ug/ml 25818768
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC = 1 ug/ml 4851320
NPT2 Others Unspecified IZ = 11 mm 4851320
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 1 ug/ml 4851320
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.5 ug/ml 4851320
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.25 ug/ml 12502337
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC = 0.25 ug/ml 12502337
NPT4835 Organism Clostridium tertium Clostridium tertium Activity = 5.6 % 2607357
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 27 mm 24597894
NPT35 Others n.a. Activity = -516 mV PubChem BioAssay data set
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 1 ug/ml 17107790
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 5820 nM 17588744
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC50 = 0.5 ug/ml 18370373
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC50 = 0.5 ug/ml 18370373
NPT189 Cell Line Vero Chlorocebus aethiops Activity = 0 % 18381238
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity = 0 % 20218673
NPT4429 Organism Prevotella loescheii Prevotella loescheii MIC50 = 0.5 ug/ml 20218673
NPT4993 Organism Prevotella disiens Prevotella disiens MIC50 = 0.5 ug/ml 20218673
NPT5913 Organism Prevotella denticola Prevotella denticola MIC50 = 0.5 ug/ml 20392638
NPT4552 Organism Bacteroides sp. Bacteroides sp. MIC = 0.125 ug/ml 20403695
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC = 1 ug/ml 20451378
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC = 0.25 ug/ml 20451378
NPT2 Others Unspecified Ratio IC50 > 55.55 19223622
NPT65 Cell Line HepG2 Homo sapiens IC50 > 100000 nM 19223622
NPT2 Others Unspecified MIC = 0.25 ug/ml 21080629
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 1 ug/ml 21080629
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 1 ug/ml 21417297
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 1 ug/ml 21476600
NPT4830 Organism Actinomyces israelii Actinomyces israelii MIC50 = 16 ug/ml 21080647
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC = 0.5 ug/ml 21634430
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC = 0.5 ug/ml 21978679
NPT2 Others Unspecified Activity = 0 % 21548582
NPT2 Others Unspecified MIC = 0.12 ug/ml 22439863
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1286 nM 23252603
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC = 0.25 ug/ml 23252603
NPT2 Others Unspecified MIC = 32 ug/ml 23252603
NPT1359 Organism Clostridium perfringens Clostridium perfringens Activity = 100 % 23252603
NPT4990 Organism Fusobacterium sp. Fusobacterium sp. Activity = 100 % 23252603
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 1 ug/ml 23252603
NPT2 Others Unspecified Activity = 0 % 23252603
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC90 = 1 ug/ml 23547652
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC90 = 4 ug/ml 23547652
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC90 = 0.25 ug/ml 23547652
NPT4823 Organism Prevotella buccae Prevotella buccae MIC50 = 4 ug/ml PubChem BioAssay data set
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 1 ug/ml 10.6019/CHEMBL1201861
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium Activity = 48.85 10.6019/CHEMBL1201861
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.25 ug/ml 10.6019/CHEMBL1201861
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 5 ug/ml 10.6019/CHEMBL1201861
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis ED50 = 5.77 mg/kg 10.6019/CHEMBL1201861
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 16.3 mm 10.6019/CHEMBL1201861
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.06 ug/ml 10.6019/CHEMBL1201861
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.25 ug/ml 10.6019/CHEMBL1201861
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.12 ug/ml 10.6019/CHEMBL1201861
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT4986 Organism Clostridium bifermentans Clostridium bifermentans MIC90 = 1 ug/ml 10.6019/CHEMBL1201861
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1810 nM 10.6019/CHEMBL1201861
NPT2 Others Unspecified IC50 > 175280 nM 10.6019/CHEMBL1201861
NPT844 Organism Trypanosoma brucei rhodesiense Trypanosoma brucei rhodesiense IC50 = 337700 nM 10.6019/CHEMBL1201861
NPT633 Organism Leishmania donovani Leishmania donovani IC50 > 175280 nM 10.6019/CHEMBL1201861
NPT6 Organism Plasmodium falciparum Plasmodium falciparum IC50 = 276940 nM 10.6019/CHEMBL1201861
NPT580 Organism Trypanosoma cruzi Trypanosoma cruzi IC50 = 278690 nM 10.6019/CHEMBL1201861
NPT633 Organism Leishmania donovani Leishmania donovani IC50 = 491360 nM 10.6019/CHEMBL1201861
NPT2 Others Unspecified IC50 = 338870 nM 10.6019/CHEMBL1201861
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC50 = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC50 = 1 ug/ml 23622981
NPT4815 Organism Neisseria meningitidis Neisseria meningitidis MIC > 100 ug/ml 24074025
NPT1522 Organism Neisseria gonorrhoeae Neisseria gonorrhoeae MIC > 100 ug/ml 24074025
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.59 ug/ml 24095016
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC <= 0.125 ug/ml 24525003
NPT4803 Organism Dialister propionicifaciens Dialister propionicifaciens MIC = 1 ug/ml 24613456
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis MIC90 = 0.25 ug/ml 24766560
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 24766560
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1640 nM 24766560
NPT2 Others Unspecified MIC90 > 128 ug/ml 24904967
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml 25380299
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 0.5 ug/ml 25233084
NPT2 Others Unspecified MIC90 = 1 ug/ml 25734520
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 4500 nM 25734520
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 2 ug/ml PubChem BioAssay data set
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 2 ug/ml PubChem BioAssay data set
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC90 = 2 ug/ml PubChem BioAssay data set
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 2 ug/ml PubChem BioAssay data set
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 0.25 ug/ml 25974739
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC = 0.12 ug/ml 25974739
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 1 ug/ml 10.1039/C4MD00252K
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.5 ug/ml 10.1039/C4MD00252K
NPT2 Others Unspecified MIC90 = 0.5 ug/ml 26376355
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii Activity = 34.1 % 26331334
NPT4802 Organism Dialister pneumosintes Dialister pneumosintes MIC90 = 8 ug/ml 26005563
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC = 0.03 ug/ml 26890114
NPT6240 Organism Clostridium sphenoides Clostridium sphenoides MIC90 = 0.25 ug/ml 26890116
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC50 > 32 ug/ml 26890116
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC90 = 0.5 ug/ml 23855338
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC90 = 2 ug/ml 23855338
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC <= 0.125 ug/ml 23914900
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 210 nM 20337496
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 1.56 ug/ml 20337496
NPT878 Organism Streptococcus mutans Streptococcus mutans MIC > 50 ug/ml 23701598
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 23558238
NPT2 Others Unspecified MIC90 = 1 ug/ml 22360639
NPT1824 Organism Clostridium sporogenes Clostridium sporogenes MIC90 = 1 ug/ml 22360639
NPT4991 Organism Porphyromonas somerae Porphyromonas somerae Activity = 0 % 11277757
NPT4824 Organism Prevotella bivia Prevotella bivia Activity = 0 % 26476665
NPT4803 Organism Dialister propionicifaciens Dialister propionicifaciens Activity <= 2 ug/ml 16180824
NPT2 Others Unspecified MIC90 = 4 ug/ml 12350153
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 350 nM 16499318
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC = 16 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC = 0.12 ug/ml PubChem BioAssay data set
NPT2900 Organism Bifidobacterium longum Bifidobacterium longum MIC = 0.12 ug/ml 22705020
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 1 ug/ml 16872140
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC50 = 0.5 ug/ml 23313635
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii Activity = 0 % 18327911
NPT2 Others Unspecified MIC50 = 1 ug/ml 21856049
NPT2 Others Unspecified MIC50 = 2 ug/ml 20346682
NPT4995 Organism Clostridium innocuum Clostridium innocuum Activity = 5.6 % 20159656
NPT4836 Organism Eggerthella lenta Eggerthella lenta Activity = 46 % 23634786
NPT19 Organism Escherichia coli Escherichia coli MIC > 300 ug/ml 23002924
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 0.5 ug/ml 12350140
NPT4429 Organism Prevotella loescheii Prevotella loescheii MIC90 = 1 ug/ml 23465614
NPT2 Others Unspecified MIC = 3.13 ug/ml 18280170
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC = 0.13 ug/ml 18280170
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC = 0.25 ug/ml 22409377
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC = 0.25 ug/ml 22409377
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium Activity = 469.79 PubChem BioAssay data set
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 5370.32 nM 18489164
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis Activity = 0 % 24617951
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC50 = 0.5 ug/ml 22831798
NPT6417 Organism Anaerococcus vaginalis Anaerococcus vaginalis MIC50 = 1 ug/ml 26042639
NPT2 Others Unspecified MIC90 = 128 ug/ml 19555084
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.5 ug/ml 16372404
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 2 ug/ml 16933872
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 2 ug/ml 17190448
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 387000 nM 11678659
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC50 = 0.25 ug/ml 15652581
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 15652581
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1810 nM 18715034
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 18 nmol/min 15104505
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 3740 nM 11975502
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 32 ug/ml 16038554
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC50 > 64 ug/ml 15497950
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC90 > 64 ug/ml 12350153
NPT4429 Organism Prevotella loescheii Prevotella loescheii MIC50 = 0.5 ug/ml 12502340
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC50 = 0.5 ug/ml 12502340
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum Activity = 100 % 24992702
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 21353775
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 18303850
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 8 ug/ml 23501116
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 32 ug/ml 23501116
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 32 ug/ml 21381696
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 16 ug/ml 21381696
NPT2 Others Unspecified MIC90 = 0.047 ug/ml 21381696
NPT2 Others Unspecified MIC50 < 0.016 ug/ml 21381696
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 2 ug/ml 18959441
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 0.5 ug 25537529
NPT2 Others Unspecified MIC50 > 64 ug/ml 25537529
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 2 ug/ml 25537529
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 0.5 ug/ml 16499320
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC50 = 1 ug/ml 12773056
NPT2 Others Unspecified Activity = 5.6 % 24797798
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 2 ug/ml 19459643
NPT2 Others Unspecified MIC50 = 0.06 ug/ml 10924170
NPT2 Others Unspecified MIC50 = 0.06 ug/ml 17190456
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 50 ug/ml 24094434
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 236 nM 20363142
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium Activity = -1.61 22119124
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC <= 0.125 ug/ml 24697496
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC50 = 0.25 ug/ml 24697496
NPT2900 Organism Bifidobacterium longum Bifidobacterium longum MIC50 = 1 ug/ml 19013823
NPT2 Others Unspecified MIC50 = 1 ug/ml 19013823
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC = 0.03 ug/ml 25554367
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC = 40000 nM 9358645
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 0.5 ug/ml 11720542
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity = 9 % 10869210
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC50 = 0.5 ug/ml 18841906
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 1517737
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC > 0.5 ug/ml 24328283
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 367000 nM 4020828
NPT2 Others Unspecified MIC = 1 ug/ml 4020828
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC50 = 0.5 ug/ml 12699389
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC90 = 1 ug/ml 12699389
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 2 ug/ml 18182300
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 6.2 ug/ml 16180824
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 1.5 ug/ml 16180824
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC < 0.8 ug/ml 16180824
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC < 0.8 ug/ml 7264682
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC < 0.8 ug/ml 15043437
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC < 0.8 ug/ml 15043437
NPT4817 Organism Finegoldia magna Finegoldia magna MIC < 0.8 ug/ml 15043437
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC > 0.12 ug/ml 18212104
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 720 nM 15920768
NPT4834 Organism Clostridium septicum Clostridium septicum MIC > 0.5 ug/ml 21144756
NPT4986 Organism Clostridium bifermentans Clostridium bifermentans MIC90 = 4 ug/ml 21142180
NPT4987 Organism Clostridium butyricum Clostridium butyricum MIC90 = 4 ug/ml 21142180
NPT4824 Organism Prevotella bivia Prevotella bivia MIC50 = 2 ug/ml 21324686
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC50 = 2 ug/ml 21356592
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 0.06 ug/ml 21663319
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 2630000 nM DrugMatrix in vitro pharmacology data
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis Activity = 0 % DrugMatrix in vitro pharmacology data
NPT160 Individual Protein TAR DNA-binding protein 43 Homo sapiens Potency 7943.3 nM DrugMatrix in vitro pharmacology data
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius MIC90 > 128 ug/ml DrugMatrix in vitro pharmacology data
NPT327 Organism Microsporum gypseum Microsporum gypseum IZ = 17 mm 22530779
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 10220855
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 12724138
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC90 = 0.25 ug/ml 12699389
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 1 ug/ml 22924480
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.12 ug/ml 21353728
NPT2 Others Unspecified MIC90 = 4 ug/ml 23252481
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 1 ug/ml 23547728
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml 23368996
NPT165 Cell Line HeLa Homo sapiens IC50 > 1000 ug/ml 10.6019/CHEMBL1201861
NPT210 Individual Protein Thyroid stimulating hormone receptor Homo sapiens Potency = 15848.9 nM 10.6019/CHEMBL1201861
NPT4835 Organism Clostridium tertium Clostridium tertium MIC50 = 1 ug/ml 10.6019/CHEMBL1201861
NPT4835 Organism Clostridium tertium Clostridium tertium MIC = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT4802 Organism Dialister pneumosintes Dialister pneumosintes Activity <= 2 ug/ml 10.6019/CHEMBL1201861
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 80 % 10.6019/CHEMBL1201861
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 73000 nM 10.6019/CHEMBL1201861
NPT312 Organism Saccharomyces cerevisiae Saccharomyces cerevisiae MIC > 32 ug/ml 10.6019/CHEMBL1201861
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC50 = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 10.6019/CHEMBL1201861
NPT4992 Organism Prevotella corporis Prevotella corporis MIC <= 0.125 ug/ml 23927763
NPT4992 Organism Prevotella corporis Prevotella corporis MIC50 = 0.5 ug/ml 24223237
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 0.25 ug/ml DrugMatrix in vivo data: Pathology
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC = 0.12 ug/ml DrugMatrix in vivo data: Pathology
NPT2 Others Unspecified Potency 749.3 nM DrugMatrix in vivo data: Pathology
NPT4820 Organism Peptostreptococcus micros Parvimonas micra Activity = 34.1 % 25536852
NPT4801 Organism Dialister micraerophilus Dialister micraerophilus Activity <= 8 ug/ml 24583355
NPT4993 Organism Prevotella disiens Prevotella disiens MIC <= 0.016 ug/ml 25804719
NPT5913 Organism Prevotella denticola Prevotella denticola MIC = 0.062 ug/ml 25804719
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC <= 0.016 ug/ml 25804719
NPT2 Others Unspecified MIC <= 0.016 ug/ml 25804719
NPT2 Others Unspecified MIC = 0.031 ug/ml 25618019
NPT2 Others Unspecified MIC <= 0.016 ug/ml 25618019
NPT4992 Organism Prevotella corporis Prevotella corporis MIC <= 0.016 ug/ml 25618019
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 0.5 ug/ml 25618019
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC <= 0.016 ug/ml 25618019
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC50 = 1 ug/ml 24087924
NPT4817 Organism Finegoldia magna Finegoldia magna MIC > 0.03 ug/ml 19691309
NPT2 Others Unspecified Potency 23.7 nM 25621853
NPT4988 Organism Clostridium cadaveris Clostridium cadaveris MIC90 = 0.25 ug/ml 23634786
NPT4822 Organism Prevotella oralis Prevotella oralis MIC90 = 8 ug/ml 19226154
NPT4824 Organism Prevotella bivia Prevotella bivia Activity = 94 % 23227781
NPT580 Organism Trypanosoma cruzi Trypanosoma cruzi IC50 > 50000 nM 22212722
NPT2 Others Unspecified MIC90 = 4 ug/ml 22506638
NPT2 Others Unspecified MIC90 = 4 ug/ml 23030826
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC = 0.5 ug/ml 23030826
NPT2 Others Unspecified Potency 76958.8 nM 26358281
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity = 0 % 15165134
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis Activity = 0 % 15165134
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii MIC = 0.12 ug/ml 17685651
NPT2 Others Unspecified MIC = 0.12 ug/ml 16562847
NPT4824 Organism Prevotella bivia Prevotella bivia Activity = 0 % 19762244
NPT4834 Organism Clostridium septicum Clostridium septicum Activity = 64 % 17088484
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC = 2 ug/ml 25237727
NPT4820 Organism Peptostreptococcus micros Parvimonas micra Activity = 0 % 22705001
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 2100 nM 22705001
NPT6417 Organism Anaerococcus vaginalis Anaerococcus vaginalis MIC50 = 0.5 ug/ml 22705001
NPT2 Others Unspecified MIC = 4 ug/ml 22705001
NPT4824 Organism Prevotella bivia Prevotella bivia Activity = 100 % 12570374
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 100 ug/ml 17854154
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC = 2 ug/ml 9784152
NPT4824 Organism Prevotella bivia Prevotella bivia MIC50 = 1 ug/ml 23268606
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.5 ug/ml 14738379
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC = 0.25 ug/ml 20815366
NPT2 Others Unspecified MIC = 0.12 ug/ml 20815366
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 GI = -14.29 % PubChem BioAssay data set
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 4 ug/ml 20058933
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 = 0.5 ug/ml 12027747
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC50 = 1 ug/ml 7528785
NPT4835 Organism Clostridium tertium Clostridium tertium MIC90 = 16 ug/ml 23964704
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 25 nM 8667357
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC90 = 4 ug/ml 1791472
NPT4992 Organism Prevotella corporis Prevotella corporis MIC90 = 1 ug/ml 18346822
NPT5913 Organism Prevotella denticola Prevotella denticola MIC90 = 1 ug/ml 19220033
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 22487595
NPT2 Others Unspecified MIC90 <= 0.12 ug/ml 11678661
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 1 ug/ml 19093843
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1800 nM 23079524
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC90 = 1 ug/ml 23316950
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.5 ug/ml 20058934
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 720 nM 17524651
NPT2 Others Unspecified MIC50 = 128 ug/ml 25856683
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 25856683
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.25 ug/ml 25856683
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv GI = 99 % 25856683
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC90 = 0.25 ug/ml 9703468
NPT4991 Organism Porphyromonas somerae Porphyromonas somerae MIC90 = 0.5 ug/ml 9703468
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC90 = 0.125 ug/ml 9703468
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC <= 0.06 ug/ml 23145909
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 2 ug/ml 23145909
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity = 100 % 23145909
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1800 nM 19653666
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml 17497807
NPT2 Others Unspecified MIC = 0.12 ug/ml 11520220
NPT2 Others Unspecified MIC = 0.12 ug/ml 17567069
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 128 ug/ml 20014752
NPT2 Others Unspecified MIC = 256 ug/ml 16472241
NPT4824 Organism Prevotella bivia Prevotella bivia MIC > 256 ug/ml 16472241
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 64 ug/ml 16472241
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 = 1 ug/ml 16472241
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 <= 0.06 ug/ml 16472241
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 > 32 ug/ml PubChem BioAssay data set
NPT65 Cell Line HepG2 Homo sapiens Activity = 92.5 % 15646539
NPT4817 Organism Finegoldia magna Finegoldia magna Activity = 9 % 24927053
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC <= 0.125 ug/ml 1453184
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC50 <= 0.125 ug/ml 21899267
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC90 = 0.5 ug/ml 21899267
NPT4823 Organism Prevotella buccae Prevotella buccae MIC90 = 1 ug/ml 25238443
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 0.037 ug/ml 10785422
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 0.23 ug/ml 11678669
NPT5068 Cell Line Spermatozoa Activity = 100 % 15217273
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 50 ug/ml 22309250
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 100 ug/ml 11754610
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 50 ug/ml 22230050
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 128000 nM 24844534
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC90 = 8 ug/ml 22624550
NPT4824 Organism Prevotella bivia Prevotella bivia MIC90 = 4 ug/ml 15217287
NPT4824 Organism Prevotella bivia Prevotella bivia MIC50 = 4 ug/ml 23876104
NPT4809 Organism Bacteroides caccae Bacteroides caccae Activity = 0 % 10.1016/S0960-894X(97)00439-3
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis Activity = 0 % 7130988
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity = 88 % 12036352
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 62.5 ug/ml 24411199
NPT2 Others Unspecified MIC90 = 1 ug/ml 19097799
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 0.12 ug/ml PubChem BioAssay data set
NPT4822 Organism Prevotella oralis Prevotella oralis MIC <= 0.125 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC = 0.5 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC50 = 16 ug/ml PubChem BioAssay data set
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1228 nM PubChem BioAssay data set
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 1 ug/ml 27311894
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.25 ug/ml 14664515
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC = 0.5 ug/ml 14664515
NPT4835 Organism Clostridium tertium Clostridium tertium Activity = 11 % 16274989
NPT2645 Organism Giardia intestinalis Giardia intestinalis Ratio EC50 = 30.2 11325240
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 1 ug/ml 10395498
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 8 ug/ml 19338315
NPT2 Others Unspecified Activity = 46 % 21705224
NPT2 Others Unspecified Activity = 46 % 24467317
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 100 ug/ml 12930149
NPT451 Organism Helicobacter pylori Helicobacter pylori Inhibition = 20 % 18271552
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Ratio ED50 = 1 24507920
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 2 ug/ml 18616221
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1810 nM 16441083
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC90 = 128 ug/ml 24702233
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC90 = 11 ug/ml 10924166
NPT29 Organism Rattus norvegicus Rattus norvegicus Inhibition = 66.3 % 23301897
NPT20 Organism Candida albicans Candida albicans IZ = 19.5 mm 20035557
NPT4991 Organism Porphyromonas somerae Porphyromonas somerae MIC90 = 0.25 ug/ml 15568791
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC = 0.12 ug/ml 26226070
NPT2 Others Unspecified MIC50 = 0.06 ug/ml 18341287
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC50 <= 0.015 ug/ml 15165148
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC50 = 74 ug/ml 8277312
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis Activity = 98 % 15270577
NPT1635 Cell Line H9c2 Rattus norvegicus Activity = 100 % 16038546
NPT1635 Cell Line H9c2 Rattus norvegicus IC50 > 200000 nM 19159272
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1450 nM 19159272
NPT2 Others Unspecified MIC90 = 128 ug/ml 10395501
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 19710 nM 25136754
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 0.21 ug/ml 25136754
NPT2 Others Unspecified MIC = 10 ug/ml 24215398
NPT2 Others Unspecified Ratio IC50 > 55.56 16309317
NPT4993 Organism Prevotella disiens Prevotella disiens MIC50 = 0.5 ug/ml 20056545
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity = 0 % 12502327
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 290 nM 18479163
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 770 nM 18479163
NPT4987 Organism Clostridium butyricum Clostridium butyricum MIC50 = 0.25 ug/ml 21314138
NPT2 Others Unspecified MIC90 = 128 ug/ml 24856903
NPT2 Others Unspecified MIC90 = 16 ug/ml 20961068
NPT5913 Organism Prevotella denticola Prevotella denticola MIC50 = 0.5 ug/ml 20961068
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC50 = 0.5 ug/ml 20961068
NPT2 Others Unspecified MIC50 > 32 ug/ml 18491867
NPT6621 Organism Entamoeba invadens Entamoeba invadens IC50 = 3000 nM 17236778
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 2500 nM 17236778
NPT5141 Organism Tritrichomonas foetus Tritrichomonas suis ED50 = 0.4 ug/ml 24900465
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 0.5 ug/ml PubChem BioAssay data set
NPT4993 Organism Prevotella disiens Prevotella disiens MIC = 0.5 ug/ml PubChem BioAssay data set
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC <= 0.125 ug/ml 22934671
NPT4835 Organism Clostridium tertium Clostridium tertium MIC = 0.12 ug/ml 25338180
NPT2 Others Unspecified MIC = 0.12 ug/ml 25338277
NPT4986 Organism Clostridium bifermentans Clostridium bifermentans MIC = 0.12 ug/ml 18364258
NPT2 Others Unspecified MIC = 0.12 ug/ml 18364258
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 23 mm 7853009
NPT1359 Organism Clostridium perfringens Clostridium perfringens Activity = 0 % 20430633
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 0.098 ug/ml 25517209
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris Activity = 0 % 15050624
NPT6240 Organism Clostridium sphenoides Clostridium sphenoides MIC50 = 0.5 ug/ml 23964644
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 0.25 ug/ml 24697496
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 1 ug/ml 8326318
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 0.25 ug/ml 8326318
NPT19 Organism Escherichia coli Escherichia coli EC50 = 8 ug/ml 8350086
NPT19 Organism Escherichia coli Escherichia coli Ratio EC50 = 3 8350086
NPT19 Organism Escherichia coli Escherichia coli EC50 = 25 ug/ml 8350086
NPT19 Organism Escherichia coli Escherichia coli EC50 = 7 ug/ml 8350086
NPT5909 Organism Propionibacterium Propionibacterium MIC = 8 ug/ml 19348465
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC90 <= 0.125 ug/ml PubChem BioAssay data set
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 1 ug/ml PubChem BioAssay data set
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC50 = 0.5 ug/ml 10579872
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 1 ug/ml 10579872
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity = 100 % 19604701
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 19604701
NPT4992 Organism Prevotella corporis Prevotella corporis MIC50 = 0.5 ug/ml 19604701
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC <= 0.125 ug/ml 23234407
NPT2 Others Unspecified MIC = 0.244 ug/ml 17346076
NPT2 Others Unspecified Activity = 0 % 20363142
NPT65 Cell Line HepG2 Homo sapiens Activity = 98 % 10075761
NPT65 Cell Line HepG2 Homo sapiens Activity >= 88 % 9868159
NPT65 Cell Line HepG2 Homo sapiens Activity >= 68 % 9868159
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 1 ug/ml 9868159
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 1 ug/ml 9868159
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC90 > 128 ug/ml 25729554
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC50 > 128 ug/ml 26273902
NPT2 Others Unspecified MIC50 = 16 ug/ml 26287401
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.5 ug/ml 22196120
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity = 0 % PubChem BioAssay data set
NPT2 Others Unspecified Potency 0.6 nM 24645629
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus MIC = 32 ug/ml 24725159
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 12713401
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 2 ug/ml 12713401
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC50 > 16 ug/ml 12713401
NPT2 Others Unspecified MIC90 = 1 ug/ml 23675610
NPT4823 Organism Prevotella buccae Prevotella buccae MIC50 = 1 ug/ml 8277312
NPT4824 Organism Prevotella bivia Prevotella bivia MIC50 = 4 ug/ml 8277312
NPT2 Others Unspecified MIC = 0.12 ug/ml 8277312
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 2030 nM 9435889
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius MIC = 32 ug/ml 9435889
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 1 ug/ml 15050613
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC50 = 0.5 ug/ml 12361403
NPT2 Others Unspecified MIC > 1 ug/ml 12109907
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 350 nM 18605717
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1226 nM 18644719
NPT6491 Organism Clostridium malenominatum Clostridium malenominatum Activity = 0 % 23062825
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC = 0.12 ug/ml 19716307
NPT2217 Individual Protein Cytochrome P450 51 Homo sapiens IC50 > 200000 nM PubChem BioAssay data set
NPT2 Others Unspecified MIC90 = 1 ug/ml 23069682
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC = 0.12 ug/ml 17708655
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC = 0.5 ug/ml PubChem BioAssay data set
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC90 = 4 ug/ml 17067151
NPT2 Others Unspecified Potency 68589.6 nM 22552195
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC > 16 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC90 > 16 ug/ml 23062825
NPT2 Others Unspecified MIC = 0.25 ug/ml 16989532
NPT2 Others Unspecified MIC90 = 1 ug/ml 10650082
NPT2 Others Unspecified MIC90 > 128 ug/ml 23634786
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC90 = 1 ug/ml 21090801
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 1 ug/ml 21090801
NPT586 Organism Giardia Giardia Potency 4099.5 nM 20825224
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 600000 nM 20825224
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 22148475
NPT189 Cell Line Vero Chlorocebus aethiops IC50 > 100000 nM 19904995
NPT4824 Organism Prevotella bivia Prevotella bivia MIC90 = 8 ug/ml 22377672
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC90 = 2 ug/ml 23013356
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 2 ug/ml 23013356
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 0.5 ug/ml 23013356
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 1 ug/ml 16499326
NPT210 Individual Protein Thyroid stimulating hormone receptor Homo sapiens Potency = 15848.9 nM 11000030
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC = 0.25 ug/ml 10924177
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis ED50 = 12.3 mg/kg 16643031
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. MIC = 0.5 ug/ml 3430167
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 12 mm 1710654
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii MIC = 0.5 ug/ml 10869203
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 8 ug/ml 11325227
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 16 ug/ml 15711537
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC = 0.03 ug/ml 15711537
NPT2 Others Unspecified MIC50 > 32 ug/ml 17923491
NPT4823 Organism Prevotella buccae Prevotella buccae Activity = 0 % 17923491
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC <= 0.125 ug/ml 17850214
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC50 = 0.25 ug/ml 18183025
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 1 ug/ml 18183025
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC = 0.5 ug/ml 18183025
NPT6283 Organism Porphyromonas levii Porphyromonas levii MIC <= 0.125 ug/ml 18183025
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC90 > 10 ug/ml 18183025
NPT185 Organism Aspergillus flavus Aspergillus flavus IZ = 17.5 mm 18183025
NPT2 Others Unspecified MIC90 = 1 ug/ml 18183025
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC50 = 2 ug/ml 10998351
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 GI = -9.9 % 10998351
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica Activity = 0 % 19734910
NPT4820 Organism Peptostreptococcus micros Parvimonas micra Activity = 9 % PubChem BioAssay data set
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC50 = 1 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified Ratio CC50/IC50 > 100 PubChem BioAssay data set
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Inhibition = 100 % 23398362
NPT2 Others Unspecified MIC > 50 ug/ml 23398362
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC90 = 1 ug/ml 23398362
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 0.5 ug/ml 23398362
NPT2 Others Unspecified MIC > 128 ug/ml 23398362
NPT2 Others Unspecified MIC = 0.5 ug/ml 23398362
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 2 ug/ml 23398362
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.5 ug/ml 23398362
NPT4835 Organism Clostridium tertium Clostridium tertium MIC50 = 2 ug/ml 12723956
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 16.3 mm 10.1016/0960-894X(95)00257-T
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 6 mm 7506311
NPT2 Others Unspecified Ratio IC50 > 55.55 7506311
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.5 ug/ml 13678412
NPT4822 Organism Prevotella oralis Prevotella oralis Activity = 0 % 15270558
NPT5906 Organism Ruminococcus sp. Ruminococcus sp. MIC = 0.25 ug/ml 15270558
NPT2 Others Unspecified MIC = 0.12 ug/ml 15270558
NPT1970 Cell Line THP-1 Homo sapiens IC50 > 1460000 nM 25819096
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 5.4 ug/ml 22989532
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 22989532
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC = 0.125 ug/ml 10650093
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1810 nM 26042639
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 8.25 log10CFU/ml 17336532
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC50 = 0.5 ug/ml 21417387
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 0.5 ug/ml 21417387
NPT2645 Organism Giardia intestinalis Giardia intestinalis EC50 = 1479.11 nM PubChem BioAssay data set
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 8 ug/ml 22738638
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 1 ug/ml 19615900
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 1 ug/ml 19615900
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 18989978
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 747700 nM 12617583
NPT2 Others Unspecified MIC90 = 128 ug/ml 12617583
NPT2900 Organism Bifidobacterium longum Bifidobacterium longum MIC90 = 128 ug/ml 12617583
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 2 ug/ml 22276679
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 99.5 % 22276679
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 100 % 22276679
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis Activity = 100 % 15332840
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 0.04 ug/ml 25237727
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 16 ug/ml 25237727
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC50 = 0.5 ug/ml 25763602
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 8158155
NPT2 Others Unspecified Ratio = 5 22583079
NPT83 Cell Line MCF7 Homo sapiens IC50 > 100000 nM 18507472
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 16 ug/ml 16919944
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 4 ug/ml 18211005
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 18211005
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 16 ug/ml 11087586
NPT2 Others Unspecified MIC = 2 ug/ml 11087586
NPT2 Others Unspecified MIC = 1 ug/ml 11087586
NPT2 Others Unspecified MIC = 4 ug/ml 11087586
NPT4809 Organism Bacteroides caccae Bacteroides caccae Activity = 0 % 21872367
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1800 nM 21872367
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 18 mm 12713412
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 5360 nM 1431942
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 2 ug/ml 15568762
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 25397992
NPT32 Organism Mus musculus Mus musculus Activity = 29.2 % 25397992
NPT32 Organism Mus musculus Mus musculus Activity = 55.9 % 25397992
NPT4802 Organism Dialister pneumosintes Dialister pneumosintes MIC = 1 ug/ml 12880316
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC90 = 1 ug/ml 8864235
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis MIC <= 0.125 ug/ml 25935644
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1220 nM 25625705
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 350 nM 25625705
NPT4835 Organism Clostridium tertium Clostridium tertium MIC = 0.5 ug/ml 12617583
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC <= 0.125 ug/ml 15620238
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC > 0.03 ug/ml 19489596
NPT451 Organism Helicobacter pylori Helicobacter pylori Inhibition = 20 % 15620248
NPT2 Others Unspecified MIC50 = 0.06 ug/ml 26854381
NPT4822 Organism Prevotella oralis Prevotella oralis MIC = 0.25 ug/ml PubChem BioAssay data set
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC50 = 0.25 ug/ml 23738539
NPT4982 Organism Collinsella aerofaciens Collinsella aerofaciens MIC50 = 1 ug/ml 9677265
NPT2 Others Unspecified MIC50 = 1 ug/ml 17536856
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 10 nmol/min 19689125
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 15 nmol/min 19689125
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 13 nmol/min 25337628
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 1 ug/ml 25333996
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 0.5 ug/ml 25333996
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.02 ug/ml 22686608
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC50 = 1 ug/ml 15974618
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 1 ug/ml 15974618
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC50 = 1 ug/ml 1431940
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC = 0.125 ug/ml 23030848
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC50 = 1 ug/ml 24460410
NPT452 Organism Helicobacter pylori SS1 Helicobacter pylori SS1 MIC = 0.5 ug/ml 8691203
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 14 mm 8691203
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 8691203
NPT2 Others Unspecified MIC50 = 0.125 ug/ml 8691203
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 8691203
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 128 ug/ml 22348826
NPT2 Others Unspecified MIC = 0.25 ug/ml 21053938
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC50 = 0.5 ug/ml 9514015
NPT1018 Organism Trypanosoma brucei Trypanosoma brucei EC50 > 500000 nM PubChem BioAssay data set
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC90 = 1 ug/ml PubChem BioAssay data set
NPT1017 Organism Cricetinae gen. sp. Cricetinae gen. sp. Activity = 15 25237727
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 1 ug/ml 12662101
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 1 ug/ml 12662101
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 1 ug/ml 21493075
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC50 <= 0.015 ug/ml 23046382
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 16 ug/ml 11000037
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC = 0.125 ug/ml 19348465
NPT4983 Organism Eubacterium limosum Eubacterium limosum MIC = 0.125 ug/ml 19778089
NPT2 Others Unspecified MIC = 2 ug/ml 19778089
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC = 0.125 ug/ml 20092288
NPT5408 Organism Capnocytophaga ochracea Capnocytophaga ochracea MIC = 1 ug/ml 20092288
NPT4832 Organism Veillonella parvula Veillonella parvula MIC = 2 ug/ml 22834941
NPT2 Others Unspecified MIC = 0.06 ug/ml 22834941
NPT2 Others Unspecified MIC = 0.25 ug/ml 22834941
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC = 0.125 ug/ml 22834941
NPT2 Others Unspecified MIC90 = 4 ug/ml 11325233
NPT4988 Organism Clostridium cadaveris Clostridium cadaveris MIC90 = 4 ug/ml 12027739
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 4 ug/ml 16038563
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 1 ug/ml 16038563
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC = 0.5 ug/ml 18952424
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 0.03 ug/ml 20196571
NPT2645 Organism Giardia intestinalis Giardia intestinalis EC50 = 3981.07 nM 1336040
NPT4823 Organism Prevotella buccae Prevotella buccae Activity = 100 % 20022253
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus Activity = 100 % 10924160
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC = 0.12 ug/ml PubChem BioAssay data set
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC90 = 0.25 ug/ml 13678412
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 13678412
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis Activity = 100 % 13678412
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 1 ug/ml 13678412
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC = 0.12 ug/ml 21561780
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 25760525
NPT83 Cell Line MCF7 Homo sapiens IC50 > 100000 nM 19904995
NPT2 Others Unspecified MIC50 > 16 ug/ml 25136754
NPT2645 Organism Giardia intestinalis Giardia intestinalis MIC = 14610 nM 24279769
NPT2 Others Unspecified IC50 = 177900 nM 22264170
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 1 ug/ml 22264170
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 99.1 % 12141859
NPT2 Others Unspecified MIC90 > 128 ug/ml 19917748
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 19813743
NPT5913 Organism Prevotella denticola Prevotella denticola MIC90 = 1 ug/ml 17722904
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 0.25 ug/ml 1965200
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 15 mm2 19344127
NPT175 Organism Enterococcus faecalis Enterococcus faecalis MIC > 100 ug/ml 12762790
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 100 ug/ml 12762790
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 16 ug/ml 12762790
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 32 ug/ml 12762790
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 128 ug/ml 12762790
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 32 ug/ml PubChem BioAssay data set
NPT65 Cell Line HepG2 Homo sapiens Activity = 95 % PubChem BioAssay data set
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 23489626
NPT6283 Organism Porphyromonas levii Porphyromonas levii MIC50 = 0.062 ug/ml 16038541
NPT2 Others Unspecified MIC50 = 0.125 ug/ml 16038541
NPT4822 Organism Prevotella oralis Prevotella oralis MIC = 0.031 ug/ml 16038541
NPT2 Others Unspecified MIC = 0.125 ug/ml 16038541
NPT2 Others Unspecified MIC = 0.25 ug/ml 16038541
NPT2 Others Unspecified MIC <= 0.016 ug/ml 16038541
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC50 = 0.031 ug/ml 16038541
NPT2 Others Unspecified MIC50 = 0.062 ug/ml 16038541
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC = 0.5 ug/ml 25710081
NPT4983 Organism Eubacterium limosum Eubacterium limosum MIC50 = 0.5 ug/ml 25856683
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC50 = 0.5 ug/ml 25856683
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 1 ug/ml 17618015
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.5 ug/ml 17618015
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 7.5 mm 14643329
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC50 = 0.5 ug/ml 15165148
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC90 = 0.25 ug/ml 6167716
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC = 0.25 ug/ml 20185316
NPT4992 Organism Prevotella corporis Prevotella corporis MIC = 0.25 ug/ml PubChem BioAssay data set
NPT1128 Organism Prevotella intermedia Prevotella intermedia Activity = 94 % DrugMatrix in vitro pharmacology data
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC = 0.5 ug/ml PubChem BioAssay data set
NPT4988 Organism Clostridium cadaveris Clostridium cadaveris MIC = 0.25 ug/ml PubChem BioAssay data set
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 100000 nM 11929285
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis Activity = 0 % 11929285
NPT2 Others Unspecified MIC = 0.12 ug/ml 11929285
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica Activity = 0 % 3598594
NPT6417 Organism Anaerococcus vaginalis Anaerococcus vaginalis MIC90 = 1 % 24128115
NPT6417 Organism Anaerococcus vaginalis Anaerococcus vaginalis Activity = 0 % 19813743
NPT4824 Organism Prevotella bivia Prevotella bivia Activity = 0 % 23501116
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 8 ug/ml 9249973
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. MIC90 = 1 ug/ml 19995673
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 32 ug/ml 20558071
NPT4834 Organism Clostridium septicum Clostridium septicum MIC90 = 16 ug/ml 20145081
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC = 0.13 ug/ml 20439614
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1810 nM 19114678
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 800 nM 19114678
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 400 nM 19114678
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC50 = 1 ug/ml 19114678
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC90 = 1 ug/ml 19114678
NPT2 Others Unspecified MIC90 = 128 ug/ml 19332671
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus MIC50 = 128 ug/ml 19258276
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius MIC50 = 128 ug/ml 19273669
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 11 nmol/min 19721064
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC90 = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC90 = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT4824 Organism Prevotella bivia Prevotella bivia MIC > 256 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC = 128 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC = 64 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC = 256 ug/ml DrugMatrix in vitro pharmacology data
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 256 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC = 16 ug/ml DrugMatrix in vitro pharmacology data
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1220 nM DrugMatrix in vitro pharmacology data
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 230 nM DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 23352753
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 1 ug/ml 15646539
NPT32 Organism Mus musculus Mus musculus LD50 = 3800 mg/kg 26264847
NPT4801 Organism Dialister micraerophilus Dialister micraerophilus MIC90 = 8 ug/ml 26344590
NPT2 Others Unspecified MIC90 = 2 ug/ml 14971898
NPT2 Others Unspecified Ratio IC50 > 55.55 10.1016/S0960-894X(97)00178-9
NPT2 Others Unspecified Potency 9441.1 nM 9301659
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 1 ug/ml 17696514
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 > 32 ug/ml 17488817
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.5 ug/ml 17488817
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 2 ug/ml 17664328
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC <= 0.125 ug/ml 20439609
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii MIC50 = 1 ug/ml 19307360
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC90 = 1 ug/ml 19223644
NPT29 Organism Rattus norvegicus Rattus norvegicus FC = 99.2 19596885
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.5 ug/ml 16472241
NPT4991 Organism Porphyromonas somerae Porphyromonas somerae MIC50 = 0.05 ug/ml DrugMatrix in vitro pharmacology data
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC > 0.03 ug/ml DrugMatrix in vitro pharmacology data
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC > 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 286 nM 22533850
NPT83 Cell Line MCF7 Homo sapiens Activity > 70 % 22533850
NPT46 Individual Protein Thyroid hormone receptor beta-1 Homo sapiens Potency = 7079.5 nM 15646539
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC50 = 16 ug/ml 25461891
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 16.3 mm 25626145
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC50 <= 0.125 ug/ml 25847765
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC = 0.5 ug/ml 25946116
NPT2 Others Unspecified MIC > 128 ug/ml 17064068
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii Activity = 46 % 19128055
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 19128055
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 4 ug/ml 19128055
NPT29 Organism Rattus norvegicus Rattus norvegicus Inhibition = 60.8 % 18183025
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 0.12 ug/ml 19665384
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 5.91 log10CFU/ml 15958589
NPT105 Individual Protein Muscleblind-like protein 1 Homo sapiens Potency 79432.8 nM 15958589
NPT4831 Organism Actinomyces meyeri Actinomyces meyeri MIC = 0.5 ug/ml 15958589
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC50 <= 0.015 ug/ml PubChem BioAssay data set
NPT4982 Organism Collinsella aerofaciens Collinsella aerofaciens MIC90 = 128 ug/ml 23252711
NPT2 Others Unspecified MIC90 = 128 ug/ml 23218601
NPT2 Others Unspecified MIC = 0.12 ug/ml 23218601
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 = 0.5 ug/ml 10.6019/CHEMBL1201861
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 32 ug/ml 10.6019/CHEMBL1201861
NPT842 Organism Leishmania mexicana Leishmania mexicana IC50 > 50000 nM 10.6019/CHEMBL1201861
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 10.6019/CHEMBL1201861
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC90 = 1 ug/ml 10.6019/CHEMBL1201861
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 5.4 ug/ml 23927974
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC = 0.25 ug/ml 18077363
NPT4831 Organism Actinomyces meyeri Actinomyces meyeri MIC50 > 32 ug/ml 16472241
NPT4830 Organism Actinomyces israelii Actinomyces israelii MIC50 > 32 ug/ml 16472241
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.25 ug/ml DrugMatrix in vitro pharmacology data
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC50 > 16 ug/ml DrugMatrix in vitro pharmacology data
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 11 mm DrugMatrix in vitro pharmacology data
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 18 mm DrugMatrix in vitro pharmacology data
NPT1824 Organism Clostridium sporogenes Clostridium sporogenes MIC = 0.12 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC = 0.12 ug/ml DrugMatrix in vitro pharmacology data
NPT4835 Organism Clostridium tertium Clostridium tertium MIC90 = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 11 mm DrugMatrix in vitro pharmacology data
NPT4817 Organism Finegoldia magna Finegoldia magna Activity = 88 % DrugMatrix in vitro pharmacology data
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity = 100 % DrugMatrix in vivo data: Hematology
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC = 0.125 ug/ml 24183741
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 3000 nM 18052326
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Inhibition = 82.69 % 23855338
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 1 ug/ml 26331426
NPT167 Organism Propionibacterium acnes Propionibacterium acnes Activity = 94.4 % 26331426
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 0.5 ug/ml 10425118
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 0.5 ug/ml 16180826
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis Activity = 2.19 % 25372480
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis Activity = 2.17 % 25372480
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis Activity = 1.63 % 25372480
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis Activity = 27.4 % 15974608
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis Activity = 23.7 % 11809064
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis Activity = 102 % 11809064
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 19105653
NPT4991 Organism Porphyromonas somerae Porphyromonas somerae MIC50 = 0.5 ug/ml 19105653
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 20.7 mm 19105653
NPT2 Others Unspecified MIC = 0.25 ug/ml 15730242
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.5 ug/ml 15730242
NPT4552 Organism Bacteroides sp. Bacteroides sp. Activity = 0 % 19548690
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 1 ug/ml 9322362
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.25 ug/ml 21868240
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 2 ug/ml 17531487
NPT91 Cell Line KB Homo sapiens IC50 > 100000 nM 19818612
NPT4834 Organism Clostridium septicum Clostridium septicum Activity = 11 % 24456578
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 0.12 ug/ml 11429990
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 0.5 ug/ml 24960143
NPT4809 Organism Bacteroides caccae Bacteroides caccae Activity = 100 % 18163584
NPT1018 Organism Trypanosoma brucei Trypanosoma brucei EC50 > 500000 nM 20634081
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC50 <= 0.015 ug/ml 9599250
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC90 = 2 ug/ml 15270566
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 17125239
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 4 ug/ml 11141097
NPT4990 Organism Fusobacterium sp. Fusobacterium sp. MIC90 = 1 ug/ml 11141097
NPT4835 Organism Clostridium tertium Clostridium tertium MIC50 = 8 ug/ml 22272829
NPT2 Others Unspecified MIC90 = 1 ug/ml 1517739
NPT4129 Organism Lactobacillus casei Lactobacillus casei MIC90 > 64 ug/ml 1517739
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC90 = 2 ug/ml 1517739
NPT4817 Organism Finegoldia magna Finegoldia magna MIC = 1 ug/ml 1517739
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml 23501116
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml 15026054
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC90 = 64 ug/ml 15026054
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 0.5 ug/ml 12542345
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 8786369
NPT634 Organism Leishmania amazonensis Leishmania amazonensis IC50 > 50000 nM 20405844
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 19 nmol/min 17685651
NPT2 Others Unspecified MIC90 = 4 ug/ml 7359534
NPT2 Others Unspecified MIC90 = 4 ug/ml 10966750
NPT19 Organism Escherichia coli Escherichia coli MIC > 50 ug/ml 10.1016/S0960-894X(00)80045-1
NPT4804 Organism Dialister invisus Dialister invisus MIC = 2 ug/ml 11206455
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC90 > 128 ug/ml 6834379
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 2 ug/ml 6834379
NPT65 Cell Line HepG2 Homo sapiens IC50 > 100000 nM 1875335
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 0.5 ug/ml 17403999
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC50 = 0.5 ug/ml 18192086
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC50 = 0.06 ug/ml 17923492
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC = 0.5 ug/ml 19445515
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC90 = 1 ug/ml 17938185
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC90 = 1 ug/ml 17938185
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 0.25 ug/ml 17938185
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. MIC50 = 1 ug/ml 19805556
NPT4831 Organism Actinomyces meyeri Actinomyces meyeri Activity = 46 % 20038616
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 290 nM 20100877
NPT2 Others Unspecified Activity = 0.489 V 20100877
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC50 = 0.5 ug/ml 20100877
NPT4129 Organism Lactobacillus casei Lactobacillus casei MIC50 > 64 ug/ml 20100877
NPT4835 Organism Clostridium tertium Clostridium tertium MIC50 = 0.5 ug/ml 20100877
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 2 ug/ml 20100877
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 300000 nM 18955522
NPT4990 Organism Fusobacterium sp. Fusobacterium sp. MIC <= 0.12 ug/ml 18955522
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 2 ug/ml 18955522
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC <= 0.125 ug/ml 18955522
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC90 = 1 ug/ml 18426954
NPT4823 Organism Prevotella buccae Prevotella buccae Activity = 94 % 19223615
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis Activity = 0 % 19223619
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae Activity = 0 % 19223619
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 0.21 ug/ml 19506065
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC <= 0.125 ug/ml 19581457
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae Activity = 0 % 19581457
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 0.25 ug/ml 20585132
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum Activity = 100 % 18625771
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 1 ug/ml 20585132
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 1 ug/ml 16472241
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC90 = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT29 Organism Rattus norvegicus Rattus norvegicus TD50 = 356.99 umol/kg DrugMatrix in vitro pharmacology data
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 8 ug/ml DrugMatrix in vitro pharmacology data
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 32 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC50 = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT2 Others Unspecified MIC90 = 0.25 ug/ml DrugMatrix in vitro pharmacology data
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 0.5 ug/ml DrugMatrix in vitro pharmacology data
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC = 0.5 ug/ml 22607678
NPT4399 Organism Actinomyces naeslundii Actinomyces naeslundii MIC50 = 16 ug/ml 22846917
NPT4822 Organism Prevotella oralis Prevotella oralis Activity = 100 % 10.1007/s00044-012-0429-8
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC = 0.25 ug/ml 23644202
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium Activity = 84.34 24775303
NPT1101 Organism Staphylococcus aureus subsp. aureus RN4220 Staphylococcus aureus subsp. aureus RN4220 GI = 16.43 % 18973387
NPT4830 Organism Actinomyces israelii Actinomyces israelii MIC = 0.5 ug/ml 26105195
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC50 = 0.5 ug/ml 18494522
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC50 = 0.5 ug/ml 18494522
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius Activity = 0 % 10560729
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 23317013
NPT1824 Organism Clostridium sporogenes Clostridium sporogenes MIC50 = 0.25 ug/ml 23317013
NPT2 Others Unspecified MIC90 = 128 ug/ml 21708464
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 2920 nM 17822299
NPT4429 Organism Prevotella loescheii Prevotella loescheii MIC = 0.25 ug/ml 19653666
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC = 0.25 ug/ml 19653666
NPT4822 Organism Prevotella oralis Prevotella oralis MIC50 = 0.5 ug/ml 26200396
NPT73 Individual Protein Solute carrier organic anion transporter family member 1B1 Homo sapiens Inhibition = 102.59 % 11412982
NPT2 Others Unspecified Potency 89.8 nM 8277313
NPT4826 Organism Fusobacterium varium Fusobacterium varium Activity = 0 % 8277313
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 16.3 mm 8277313
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 4 ug/ml 24957203
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 24957203
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 8 ug/ml 24957203
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 16 ug/ml 24957203
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 24960143
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 0.5 ug/ml 24960143
NPT65 Cell Line HepG2 Homo sapiens IC50 > 100000 nM 8350092
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC <= 0.125 ug/ml 17253856
NPT2 Others Unspecified IZ = 14 mm 17503850
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1230 nM 10924166
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.12 ug/ml 9392875
NPT2 Others Unspecified MIC = 0.12 ug/ml 9392875
NPT2 Others Unspecified MIC90 = 2 ug/ml 25443644
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC90 = 2 ug/ml 12542345
NPT4823 Organism Prevotella buccae Prevotella buccae MIC90 = 8 ug/ml 10096862
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.5 ug/ml 15921404
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 50 ug/ml 15497961
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 25 ug/ml 15497961
NPT4987 Organism Clostridium butyricum Clostridium butyricum MIC50 = 0.5 ug/ml 16499337
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 16499337
NPT4986 Organism Clostridium bifermentans Clostridium bifermentans MIC50 = 0.5 ug/ml 12350149
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC <= 0.125 ug/ml 18826276
NPT5909 Organism Propionibacterium Propionibacterium Activity = 92.3 % 18507474
NPT2 Others Unspecified MIC50 = 1 ug/ml 23347584
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 1 ug/ml 20045651
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 29 nmol/min 19845338
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 15 nmol/min 20028029
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 20 nmol/min 20028029
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 18 nmol/min 17125238
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 31 nmol/min 19159277
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 18 nmol/min 14640513
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 13 nmol/min 16643040
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 9 nmol/min 16643040
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 25 nmol/min 16643040
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 22 nmol/min 8786363
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC50 = 1 ug/ml 21214226
NPT4817 Organism Finegoldia magna Finegoldia magna Activity = 0 % 1431942
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 1800632
NPT2 Others Unspecified MIC90 = 2 ug/ml 1800632
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 1 ug/ml 17618015
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 24645629
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC = 0.5 ug/ml 23978065
NPT83 Cell Line MCF7 Homo sapiens IC50 > 250000 nM 17315965
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC = 0.25 ug/ml 22168134
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC = 0.12 ug/ml 12662097
NPT2 Others Unspecified MIC90 = 4 ug/ml 18088097
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. Activity = 98.1 % 10579870
NPT2 Others Unspecified Activity = 100 % 10579870
NPT2 Others Unspecified MIC < 0.016 ug/ml 20521771
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 11858756
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 18303850
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC = 1 ug/ml 18278869
NPT2 Others Unspecified MIC = 0.06 ug/ml 18278869
NPT5913 Organism Prevotella denticola Prevotella denticola MIC = 0.25 ug/ml 18278869
NPT2 Others Unspecified MIC = 0.25 ug/ml 11277742
NPT2 Others Unspecified MIC = 0.125 ug/ml 11277742
NPT2 Others Unspecified MIC = 0.03 ug/ml 11520216
NPT2 Others Unspecified MIC = 0.25 ug/ml 1431932
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC = 0.25 ug/ml 1431932
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC <= 0.015 ug/ml 1431932
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 11520220
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 7964787
NPT2 Others Unspecified MIC = 0.5 ug/ml 19555124
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 2 ug/ml 18154270
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus Activity = 0 % 18491867
NPT72 Individual Protein Solute carrier organic anion transporter family member 1B3 Homo sapiens Inhibition = 98.27 % 19245261
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 771 nM 24479418
NPT2 Others Unspecified MIC = 0.12 ug/ml 24412339
NPT2 Others Unspecified MIC90 = 1 ug/ml 22934537
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 1 ug/ml 22934537
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC = 1 ug/ml 18977148
NPT2 Others Unspecified MIC50 = 1 ug/ml 18977148
NPT2 Others Unspecified MIC50 = 1 ug/ml 18220356
NPT2 Others Unspecified MIC50 = 1 ug/ml 11678652
NPT83 Cell Line MCF7 Homo sapiens Activity = 100 % 23265253
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 5.4 ug/ml 12662097
NPT2910 Organism Campylobacter jejuni Campylobacter jejuni MIC = 30 ug/ml 12662097
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 1.75 ug/ml 19226152
NPT2 Others Unspecified MIC > 16 ug/ml 22938151
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC = 1 ug/ml 17125218
NPT4986 Organism Clostridium bifermentans Clostridium bifermentans MIC = 0.25 ug/ml 20815366
NPT4988 Organism Clostridium cadaveris Clostridium cadaveris MIC <= 0.125 ug/ml 20815366
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1800 nM 11720532
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC90 = 2 ug/ml 22901896
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC90 = 0.25 ug/ml 22901896
NPT4830 Organism Actinomyces israelii Actinomyces israelii MIC90 > 128 ug/ml 9599260
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus Activity = 0 % 18278868
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 2 ug/ml 10869203
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus MIC90 > 128 ug/ml 20163893
NPT2 Others Unspecified MIC90 > 128 ug/ml 20163893
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 15787431
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml 15568791
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 = 0.5 ug/ml 12502331
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC <= 0.125 ug/ml 10.1016/S0960-894X(97)00391-0
NPT2 Others Unspecified MIC = 0.12 ug/ml 11374948
NPT19 Organism Escherichia coli Escherichia coli MIC > 100 ug/ml 17190454
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 100 ug/ml 17190454
NPT3495 Organism Morganella morganii Morganella morganii MIC > 100 ug/ml 17190454
NPT2 Others Unspecified MIC50 > 32 ug/ml 17950603
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC50 > 32 ug/ml 17950603
NPT4822 Organism Prevotella oralis Prevotella oralis MIC50 = 0.25 ug/ml 21288727
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC50 = 0.125 ug/ml 8984155
NPT5913 Organism Prevotella denticola Prevotella denticola MIC50 = 0.125 ug/ml 8984155
NPT4992 Organism Prevotella corporis Prevotella corporis MIC50 = 0.062 ug/ml 8984155
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 8984155
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 <= 0.016 ug/ml 26218649
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 26218649
NPT4993 Organism Prevotella disiens Prevotella disiens MIC50 = 0.062 ug/ml 26218649
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC50 = 1 ug/ml 24601675
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 2 ug/ml 12141856
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 1 ug/ml 16441074
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 1 ug/ml 11908979
NPT2 Others Unspecified MIC = 0.12 ug/ml 11908979
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 1 ug/ml 11908979
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC50 = 1 ug/ml 11908979
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC50 = 1 ug/ml 11908979
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 8.75 mm 11908979
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC90 > 32 ug/ml 26287548
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 0.22 ug/ml 20050684
NPT1127 Organism Porphyromonas gingivalis Porphyromonas gingivalis MIC <= 0.125 ug/ml 11374948
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC = 0.25 ug/ml 16989518
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC = 0.25 ug/ml 23701598
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 1 ug/ml 15497936
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC = 0.25 ug/ml 15497936
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC <= 0.125 ug/ml 15497936
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 2700 nM 19962903
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 5780 nM 10650082
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.2 ug/ml 24645629
NPT2910 Organism Campylobacter jejuni Campylobacter jejuni MIC = 30 ug/ml 24645629
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.59 ug/ml 24645629
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 1.75 ug/ml 24645629
NPT4815 Organism Neisseria meningitidis Neisseria meningitidis MIC > 100 ug/ml 24645629
NPT1522 Organism Neisseria gonorrhoeae Neisseria gonorrhoeae MIC > 100 ug/ml 24645629
NPT1635 Cell Line H9c2 Rattus norvegicus IC50 > 116000 nM 24645629
NPT31 Individual Protein Cyclooxygenase-2 Homo sapiens Inhibition = 17 % 22136523
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC90 = 2 ug/ml 23249297
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 1 ug/ml 23249297
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC50 = 0.25 ug/ml 22742761
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. MIC90 = 32 ug/ml 20361780
NPT94 Individual Protein Aldehyde dehydrogenase 1A1 Homo sapiens Potency = 7943.3 nM 12027740
NPT1128 Organism Prevotella intermedia Prevotella intermedia Activity = 0 % PubChem BioAssay data set
NPT4077 Organism Escherichia coli DH5[alpha] Escherichia coli DH5[alpha] GI = 8.2 % PubChem BioAssay data set
NPT1359 Organism Clostridium perfringens Clostridium perfringens Activity = 64 % PubChem BioAssay data set
NPT4995 Organism Clostridium innocuum Clostridium innocuum Activity = 0 % 23964644
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme Activity = 0 % 18440233
NPT1128 Organism Prevotella intermedia Prevotella intermedia Activity = 100 % 24144848
NPT83 Cell Line MCF7 Homo sapiens IC50 > 250000 nM 20515062
NPT83 Cell Line MCF7 Homo sapiens IC50 > 100000 nM 8792624
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 26358281
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC90 = 1 ug/ml 17689080
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC = 1 ug/ml 23465614
NPT2 Others Unspecified MIC = 16 ug/ml 17988095
NPT2 Others Unspecified MIC = 64 ug/ml 17988095
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC <= 0.015 ug/ml 17988095
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.5 ug/ml 21082802
NPT2 Others Unspecified MIC = 1 ug/ml 21082802
NPT4834 Organism Clostridium septicum Clostridium septicum MIC = 1 ug/ml 21082802
NPT2 Others Unspecified MIC = 16 ug/ml 20158243
NPT2 Others Unspecified MIC = 1.56 ug/ml 22182501
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 0.1 ug/ml 12828469
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 0.25 ug/ml 22742761
NPT2 Others Unspecified Ratio IC50 > 64.44 PubChem BioAssay data set
NPT4804 Organism Dialister invisus Dialister invisus Activity <= 2 ug/ml 16872130
NPT2 Others Unspecified Potency 68589.6 nM 18763827
NPT2 Others Unspecified MIC = 0.5 ug/ml 16872131
NPT91 Cell Line KB Homo sapiens IC50 > 100000 nM 22608855
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 0.5 ug/ml 12361396
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC = 0.5 ug/ml 10377223
NPT2 Others Unspecified MIC <= 0.78 ug/ml 10377223
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC90 = 1 ug/ml 9873604
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 14 nmol/min 15711537
NPT2 Others Unspecified Ratio IC50 > 55.55 15711537
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 55850 nM 18183025
NPT4826 Organism Fusobacterium varium Fusobacterium varium Activity = 100 % 18183025
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 5360 nM 18183025
NPT2 Others Unspecified MIC = 256 ug/ml 17850214
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 128 ug/ml 17850214
NPT4824 Organism Prevotella bivia Prevotella bivia MIC > 256 ug/ml 17850214
NPT2 Others Unspecified MIC = 128 ug/ml 18183025
NPT2 Others Unspecified MIC = 256 ug/ml 18183025
NPT2 Others Unspecified MIC = 64 ug/ml 18183025
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1220 nM 18183025
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 20932756
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2050000 nM PubChem BioAssay data set
NPT1824 Organism Clostridium sporogenes Clostridium sporogenes MIC = 45600 nM PubChem BioAssay data set
NPT1140 Organism Escherichia coli ATCC 8739 Escherichia coli ATCC 8739 MIC = 5480000 nM PubChem BioAssay data set
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 7.59 mm2 PubChem BioAssay data set
NPT1228 Organism Streptococcus pyogenes Streptococcus pyogenes MIC > 300 ug/ml PubChem BioAssay data set
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 300 ug/ml PubChem BioAssay data set
NPT4851 Organism Mycoplasma gallisepticum Mycoplasma gallisepticum MIC > 300 ug/ml 22037378
NPT4802 Organism Dialister pneumosintes Dialister pneumosintes Activity <= 8 ug/ml 22037378
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC90 = 0.5 ug/ml 22037378
NPT2 Others Unspecified MIC90 = 8 ug/ml 22037378
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC90 = 2 ug/ml 22037378
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 11700 nM 22037378
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 1 ug/ml 22037378
NPT2 Others Unspecified MIC <= 0.125 ug/ml 22037378
NPT4823 Organism Prevotella buccae Prevotella buccae MIC50 = 1 ug/ml 22037378
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 1 ug/ml 22037378
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 1 ug/ml 22037378
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 1 ug/ml 22037378
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity = 88 % 22037378
NPT1359 Organism Clostridium perfringens Clostridium perfringens Activity = 100 % 22037378
NPT2 Others Unspecified Ratio IC50 > 55.55 22037378
NPT2 Others Unspecified IC50 = 5400 nM DrugMatrix in vitro pharmacology data
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC <= 0.125 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC50 = 1 ug/ml PubChem BioAssay data set
NPT5913 Organism Prevotella denticola Prevotella denticola MIC90 = 1 ug/ml PubChem BioAssay data set
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC90 = 1 ug/ml PubChem BioAssay data set
NPT1017 Organism Cricetinae gen. sp. Cricetinae gen. sp. Activity = 15 PubChem BioAssay data set
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC90 = 0.25 ug/ml 23398362
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 0.54 ug/ml 23398362
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 0.5 ug/ml 23398362
NPT2 Others Unspecified MIC = 0.016 ug/ml 23398362
NPT5906 Organism Ruminococcus sp. Ruminococcus sp. MIC < 0.125 ug/ml 23398362
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC50 = 1 ug/ml 23398362
NPT2 Others Unspecified Ratio IC50 > 137.9 23398362
NPT83 Cell Line MCF7 Homo sapiens IC50 > 250000 nM 23398362
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 100 % 23398362
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 23398362
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 1 ug/ml 23398362
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.25 ug/ml 23398362
NPT4992 Organism Prevotella corporis Prevotella corporis MIC50 = 0.5 ug/ml 18077363
NPT2645 Organism Giardia intestinalis Giardia intestinalis FC = 1000 22624550
NPT2645 Organism Giardia intestinalis Giardia intestinalis Ratio EC50 = 6.46 22624550
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 1 ug/ml 22703163
NPT566 Organism Salmonella typhimurium Salmonella enterica subsp. enterica serovar Typhimurium Ratio = 10.1 15974609
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 16 ug/ml 14695801
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC = 0.12 ug/ml 10869195
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC > 0.5 ug/ml 10869195
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 9917283
NPT4835 Organism Clostridium tertium Clostridium tertium MIC > 0.5 ug/ml 19231864
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 2 ug/ml 16506833
NPT2 Others Unspecified MIC > 128 ug/ml 16506833
NPT4128 Organism Lactobacillus fermentum Lactobacillus fermentum MIC > 128 ug/ml 16506833
NPT1825 Organism Lactobacillus plantarum Lactobacillus plantarum MIC > 128 ug/ml 16506833
NPT4129 Organism Lactobacillus casei Lactobacillus casei MIC > 128 ug/ml 16506833
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC50 = 2 ug/ml 24697496
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 580 nM 24900585
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC <= 0.125 ug/ml 25203782
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 1 ug/ml 25203782
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC50 = 0.5 ug/ml 26054247
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1.22 ug/ml 22194678
NPT5913 Organism Prevotella denticola Prevotella denticola MIC <= 0.125 ug/ml 15646539
NPT4830 Organism Actinomyces israelii Actinomyces israelii Activity = 46 % 19133758
NPT4990 Organism Fusobacterium sp. Fusobacterium sp. MIC50 <= 0.015 ug/ml 19691309
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC90 = 1 ug/ml 20092288
NPT2 Others Unspecified MIC90 > 31 ug/ml 19754128
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC90 > 32 ug/ml 19761234
NPT5906 Organism Ruminococcus sp. Ruminococcus sp. MIC50 = 0.5 ug/ml 8254344
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.5 ug/ml 19702283
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC90 = 0.5 ug/ml 18723353
NPT2 Others Unspecified MIC90 = 128 ug/ml 25729554
NPT2 Others Unspecified MIC = 1 ug/ml 15043442
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 0.12 ug/ml 12444685
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC = 0.12 ug/ml 23905700
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 1 ug/ml 18694644
NPT474 Organism Plasmodium berghei Plasmodium berghei IC50 > 50000 nM 21377877
NPT580 Organism Trypanosoma cruzi Trypanosoma cruzi IC50 > 50000 nM 12444693
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC50 <= 0.12 ug/ml PubChem BioAssay data set
NPT4823 Organism Prevotella buccae Prevotella buccae MIC90 = 2 ug/ml 22500574
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC <= 0.125 ug/ml 22500574
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 290 nM 22500574
NPT2 Others Unspecified MIC = 0.5 ug/ml 12105963
NPT2 Others Unspecified MIC90 = 2 ug/ml 12105963
NPT2 Others Unspecified MIC50 = 1 ug/ml 12105963
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 1 ug/ml 11929285
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 1 ug/ml 11929285
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 16 ug/ml 11929285
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 8 ug/ml 11929285
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC50 = 0.25 ug/ml 11929285
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC90 = 8 ug/ml 11929285
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 0.031 ug/ml 11929285
NPT105 Individual Protein Muscleblind-like protein 1 Homo sapiens Potency 25118.9 nM 12105963
NPT4817 Organism Finegoldia magna Finegoldia magna MIC = 0.25 ug/ml 12105963
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml 12105963
NPT2 Others Unspecified MIC = 0.12 ug/ml 12105963
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC > 100 ug/ml 1602301
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 4160 nM 15921413
NPT2 Others Unspecified MIC = 0.12 ug/ml 19902967
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC90 = 1 ug/ml 25419616
NPT2 Others Unspecified Potency 61130.6 nM 14640526
NPT4820 Organism Peptostreptococcus micros Parvimonas micra Activity = 0 % PubChem BioAssay data set
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 1 ug/ml 22280363
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 2 ug/ml 22280363
NPT2 Others Unspecified MIC50 = 1 ug/ml 19715320
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 350 nM 19715320
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 216 nM 19715320
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 2 ug/ml 23391590
NPT6492 Organism Clostridium aminovalericum Clostridium aminovalericum MIC90 = 0.25 ug/ml 25618017
NPT4988 Organism Clostridium cadaveris Clostridium cadaveris MIC50 = 0.125 ug/ml 26711891
NPT2 Others Unspecified MIC > 128 ug/ml 18824363
NPT2 Others Unspecified MIC = 8 ug/ml 9051909
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 25554367
NPT2 Others Unspecified MIC = 0.5 ug/ml 19702283
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC = 0.5 ug/ml 8254346
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.25 ug/ml 8254346
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus Activity = 0 % 19376614
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis Activity = 0 % 18720971
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus Activity = 0 % 20384293
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC90 = 2 ug/ml 25763602
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 2 ug/ml 25763602
NPT4823 Organism Prevotella buccae Prevotella buccae Activity = 0 % 25763602
NPT2 Others Unspecified Activity = 46 % 10346943
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum Activity = 11 % 23376010
NPT4831 Organism Actinomyces meyeri Actinomyces meyeri MIC50 = 16 ug/ml 23734721
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1226 nM 12444692
NPT4822 Organism Prevotella oralis Prevotella oralis MIC = 0.5 ug/ml 17512741
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis Activity = 0 % 18771242
NPT2 Others Unspecified MIC = 0.12 ug/ml 19105653
NPT2 Others Unspecified MIC > 128 ug/ml 2681536
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC > 128 ug/ml 16441066
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC = 0.5 ug/ml 16441066
NPT4990 Organism Fusobacterium sp. Fusobacterium sp. MIC50 = 0.25 ug/ml 24063567
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 2 ug/ml 24063567
NPT4987 Organism Clostridium butyricum Clostridium butyricum MIC = 0.12 ug/ml 17988094
NPT4822 Organism Prevotella oralis Prevotella oralis MIC50 = 4 ug/ml 11262075
NPT29 Organism Rattus norvegicus Rattus norvegicus Inhibition = 58.9 % 18163582
NPT1522 Organism Neisseria gonorrhoeae Neisseria gonorrhoeae MIC > 100 ug/ml 9514015
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis Activity = 0 % PubChem BioAssay data set
NPT4824 Organism Prevotella bivia Prevotella bivia MIC90 = 1 ug/ml 18288804
NPT4823 Organism Prevotella buccae Prevotella buccae MIC90 = 1 ug/ml 17665952
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC90 = 4 ug/ml 18177012
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 1 ug/ml 18177012
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius Activity = 9 % 25710081
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC = 0.5 ug/ml 15332848
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC90 = 1 ug/ml 11720540
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 1 ug/ml 22831798
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC90 = 2 ug/ml 22831798
NPT2 Others Unspecified MIC90 > 128 ug/ml 10869229
NPT2 Others Unspecified MIC90 = 1 ug/ml 10691710
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC90 = 1 ug/ml 10691710
NPT2 Others Unspecified Ratio IC50 > 22.22 17536859
NPT4824 Organism Prevotella bivia Prevotella bivia MIC90 = 2 ug/ml 15620242
NPT4823 Organism Prevotella buccae Prevotella buccae MIC90 = 1 ug/ml 23092389
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC = 0.5 ug/ml 23489626
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC90 = 4 ug/ml 23395661
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 0.5 ug/ml 24913558
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 2 ug/ml 24913558
NPT189 Cell Line Vero Chlorocebus aethiops Activity = 903 nM 24842703
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 2 ug/ml 18314958
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 5800 nM 19739600
NPT5909 Organism Propionibacterium Propionibacterium MIC90 = 32 ug/ml 23149227
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 770 nM 15104488
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC50 = 0.06 ug/ml 17125236
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC90 = 2 ug/ml 16792412
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 2 ug/ml 16792412
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 1 ug/ml 16792412
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 1 ug/ml 16792412
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. MIC <= 0.03 ug/ml 19453174
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC = 0.125 ug/ml 19453174
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC90 <= 0.125 ug/ml 23031087
NPT2 Others Unspecified MBC = 12.5 ug/ml PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori MBC = 50 ug/ml PubChem BioAssay data set
NPT2 Others Unspecified MIC90 = 1 ug/ml 26854381
NPT4981 Organism Clostridium sordellii Clostridium sordellii MIC90 = 1 ug/ml 20627740
NPT2 Others Unspecified MIC90 = 4 ug/ml PubChem BioAssay data set
NPT4823 Organism Prevotella buccae Prevotella buccae MIC90 = 8 ug/ml 24251417
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 128 ug/ml 17190442
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii Activity = 0 % 17190444
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis Activity = 0 % 17190444
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus Activity = 0 % 17190444
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 16 ug/ml 22168134
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 8.14 log10CFU/ml 2553871
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 8.3 log10CFU/ml 1919590
NPT5914 Organism Prevotella nigrescens Prevotella nigrescens MIC50 = 0.5 ug/ml 22612410
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 = 0.5 ug/ml 26048785
NPT2 Others Unspecified MIC > 50 ug/ml 22676269
NPT4830 Organism Actinomyces israelii Actinomyces israelii Activity = 46 % 19921834
NPT2 Others Unspecified Potency 3349.1 nM 19921834
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1820 nM 19835393
NPT2 Others Unspecified Ratio IC50 > 55.24 9677282
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml 9677282
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.25 ug/ml 22444684
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.25 ug/ml 22444684
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 0.5 ug/ml 22444684
NPT2 Others Unspecified MIC = 0.5 ug/ml 7264681
NPT4831 Organism Actinomyces meyeri Actinomyces meyeri MIC90 > 32 ug/ml 9514009
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 25856683
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC50 = 0.25 ug/ml 25856683
NPT2940 Organism Clostridium difficile Clostridium difficile MIC >= 8 ug/ml 11374943
NPT2 Others Unspecified Activity = 46 % 11374943
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 23145909
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 = 0.5 ug/ml 23145909
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 15270556
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 2920 nM 11551768
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 5.4 ug/ml 6481359
NPT6492 Organism Clostridium aminovalericum Clostridium aminovalericum MIC50 = 0.125 ug/ml 20236738
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 1 ug/ml PubChem BioAssay data set
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum Activity = 0 % PubChem BioAssay data set
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 11858752
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 1 ug/ml 15787444
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 2 ug/ml 15787444
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 4 ug/ml 15787444
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 290 nM 10924160
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 10924160
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 1 ug/ml 10924160
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 8 ug/ml 10924160
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 5360 nM 20462230
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 290 nM 20521771
NPT616 Cell Line MDCK Canis lupus familiaris CC50 = 68000 nM 20521771
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 770 nM 20521771
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 14 mm 23805995
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.25 ug/ml 8759172
NPT2 Others Unspecified Ratio LD50/ED50 = 658 26546220
NPT4802 Organism Dialister pneumosintes Dialister pneumosintes MIC50 = 4 ug/ml 20674349
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 1 ug/ml 20542692
NPT4984 Organism Anaerococcus tetradius Anaerococcus tetradius MIC = 0.5 ug/ml 20542692
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC <= 0.125 ug/ml 19215141
NPT4994 Organism Clostridium clostridioforme Clostridium clostridioforme MIC <= 0.12 ug/ml 15043411
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 0.21 ug/ml 19115839
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 0.04 ug/ml 19115839
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 16 ug/ml 19762244
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.5 ug/ml 22546674
NPT483 Individual Protein Prelamin-A/C Homo sapiens Potency = 2511.9 nM 18808182
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1560 nM 20038128
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 20402524
NPT4988 Organism Clostridium cadaveris Clostridium cadaveris MIC50 = 0.5 ug/ml 20402524
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Inhibition = 93.96 % 20430633
NPT2 Others Unspecified Ratio CC50/IC50 > 10 23772699
NPT2 Others Unspecified MIC50 = 1 ug/ml 9182126
NPT4836 Organism Eggerthella lenta Eggerthella lenta MIC50 = 1 ug/ml 9182126
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 32 ug/ml 23891163
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 32 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 36 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 19 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 27 nmol/min PubChem BioAssay data set
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 33 nmol/min PubChem BioAssay data set
NPT4988 Organism Clostridium cadaveris Clostridium cadaveris Activity = 0 % PubChem BioAssay data set
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC50 = 0.25 ug/ml 16792409
NPT4823 Organism Prevotella buccae Prevotella buccae MIC50 = 0.5 ug/ml 9307570
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC50 = 0.5 ug/ml 23558238
NPT4817 Organism Finegoldia magna Finegoldia magna Activity = 100 % 23558238
NPT2 Others Unspecified MIC = 0.125 ug/ml 8229009
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 2 ug/ml 18831569
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC = 0.25 ug/ml 18831569
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml 25856683
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 1 ug/ml 26200131
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 1 ug/ml 26200131
NPT2 Others Unspecified AC50 2000 nM 21489793
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis Activity = 100 % 16643042
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.5 ug/ml 16499316
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 1 ug/ml 10479314
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 32 ug/ml 21332115
NPT2 Others Unspecified MIC = 2 ug/ml 18803421
NPT2 Others Unspecified MIC = 2 ug/ml 24063582
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 2 ug/ml 19601607
NPT167 Organism Propionibacterium acnes Propionibacterium acnes Activity = 0 % 19601607
NPT2 Others Unspecified MIC <= 0.06 ug/ml 20624681
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC <= 0.06 ug/ml 20624681
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.125 ug/ml 20232858
NPT4833 Organism Clostridium paraputrificum Clostridium paraputrificum MIC90 = 16 ug/ml 19072548
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC50 = 0.5 ug/ml 20155932
NPT2 Others Unspecified MIC = 2 ug/ml 18177014
NPT2 Others Unspecified MIC = 0.5 ug/ml 18177014
NPT2 Others Unspecified MIC = 1 ug/ml 18177014
NPT2 Others Unspecified MIC = 2 ug/ml 26035018
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 1 ug/ml 26035018
NPT2 Others Unspecified MIC = 0.5 ug/ml 26035018
NPT4992 Organism Prevotella corporis Prevotella corporis MIC = 0.125 ug/ml 26035018
NPT2 Others Unspecified MIC90 = 4 ug/ml 24601675
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 24601675
NPT2 Others Unspecified Activity = 46 % 24601675
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC90 = 2 ug/ml 24601675
NPT2 Others Unspecified Ratio IC50/EC50 = 2291 23571415
NPT165 Cell Line HeLa Homo sapiens IC50 = 6025595.86 nM 25330401
NPT2645 Organism Giardia intestinalis Giardia intestinalis EC50 = 2630.27 nM 12217376
NPT2645 Organism Giardia intestinalis Giardia intestinalis EC50 = 2630 nM 12217376
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 0.5 ug/ml 17958396
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC90 > 16 ug/ml 17958396
NPT4982 Organism Collinsella aerofaciens Collinsella aerofaciens MIC = 0.12 ug/ml 17958396
NPT2 Others Unspecified MIC = 0.12 ug/ml 17958396
NPT1018 Organism Trypanosoma brucei Trypanosoma brucei EC50 > 500000 nM 23944963
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC90 = 1 ug/ml 18630962
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC50 = 1 ug/ml 18630962
NPT2 Others Unspecified MIC90 = 1 ug/ml 22506638
NPT4077 Organism Escherichia coli DH5[alpha] Escherichia coli DH5[alpha] GI = 14.96 % 8133298
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis Activity = 8.5 log CFU 23265253
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis Activity = 6.9 log CFU 23043462
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC50 = 0.5 ug/ml PubChem BioAssay data set
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 0.5 ug/ml 26327273
NPT2940 Organism Clostridium difficile Clostridium difficile MIC = 0.06 ug/ml 26327273
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.12 ug/ml 23488669
NPT2 Others Unspecified MIC50 > 16 ug/ml 25710081
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC = 1 ug/ml 12880316
NPT4801 Organism Dialister micraerophilus Dialister micraerophilus Activity <= 2 ug/ml 9358640
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 0.19 ug/ml 17125236
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.094 ug/ml 17125236
NPT2 Others Unspecified MIC90 = 2 ug/ml 12502326
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC90 = 0.5 ug/ml 12502326
NPT4831 Organism Actinomyces meyeri Actinomyces meyeri MIC90 > 128 ug/ml 17035027
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 1 ug/ml 17035027
NPT4817 Organism Finegoldia magna Finegoldia magna Activity = 0 % PubChem BioAssay data set
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 2 ug/ml 17346076
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 12193011
NPT2 Others Unspecified MIC90 = 0.5 ug/ml 23691978
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 23691978
NPT6283 Organism Porphyromonas levii Porphyromonas levii MIC90 = 0.125 ug/ml 23691978
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC90 = 0.125 ug/ml 23691978
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 23691978
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 23691978
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 200 ug/ml 20028134
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC90 = 32 ug/ml 20028134
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC <= 0.125 ug/ml 2016726
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC50 = 2 ug/ml 14611845
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC90 = 1 ug/ml 15177454
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC90 = 1 ug/ml 16949283
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 6 mm 17088489
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC50 = 0.5 ug/ml 17261619
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC90 = 1 ug/ml 17261619
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 3200 nM 17261619
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.5 ug/ml 17261619
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 1 ug/ml 17261619
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC90 = 2 ug/ml 18004816
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC = 0.25 ug/ml 17353251
NPT165 Cell Line HeLa Homo sapiens IC50 > 1000 ug/ml 19058973
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 12.5 ug/ml 19058973
NPT4835 Organism Clostridium tertium Clostridium tertium MIC90 = 1 ug/ml 17638702
NPT2 Others Unspecified MIC = 0.5 ug/ml 17923494
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 64 ug/ml 18070962
NPT189 Cell Line Vero Chlorocebus aethiops CC50 > 600000 nM 20070106
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 316.23 nM 20000576
NPT2 Others Unspecified MIC50 = 0.5 ug/ml 20038618
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 20038618
NPT1171 Cell Line HEp-2 Homo sapiens Activity = 869.33 nM 18172002
NPT4826 Organism Fusobacterium varium Fusobacterium varium MIC50 <= 0.12 ug/ml 20194693
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC50 <= 0.125 ug/ml 20194693
NPT4832 Organism Veillonella parvula Veillonella parvula MIC = 1 ug/ml 20368405
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC > 300 ug/ml 18644958
NPT6240 Organism Clostridium sphenoides Clostridium sphenoides Activity = 0 % 18809939
NPT1128 Organism Prevotella intermedia Prevotella intermedia Activity = 0 % 18809939
NPT3173 Organism Arthroderma benhamiae Arthroderma benhamiae MIC > 32 ug/ml 18809945
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv MIC90 > 32 ug/ml 18809945
NPT328 Organism Epidermophyton floccosum Epidermophyton floccosum MIC > 32 ug/ml 18809945
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC = 0.5 ug/ml 20350950
NPT2 Others Unspecified MIC50 = 4 ug/ml 18710917
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1800 nM 18710917
NPT2 Others Unspecified AC50 5011.9 nM 18710917
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1460 nM 18710917
NPT2 Others Unspecified AC50 7079.5 nM 20801553
NPT2 Others Unspecified MIC > 128 ug/ml 18285482
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC = 0.125 ug/ml 18285482
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC = 1 ug/ml 18285482
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC = 1 ug/ml 18285482
NPT2 Others Unspecified MIC = 1 ug/ml 18285482
NPT2 Others Unspecified MIC = 0.5 ug/ml 18285482
NPT5315 Organism Streptococcus intermedius Streptococcus intermedius MIC > 128 ug/ml 18285485
NPT5314 Organism Streptococcus constellatus Streptococcus constellatus MIC > 128 ug/ml 18285485
NPT4831 Organism Actinomyces meyeri Actinomyces meyeri Activity = 46 % 18378706
NPT2 Others Unspecified MIC = 0.12 ug/ml 18519713
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 8.01 log10CFU/ml 19029325
NPT16 Organism Staphylococcus aureus Staphylococcus aureus Activity = 6.45 log10CFU/ml 19029325
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii MIC = 0.25 ug/ml 19029328
NPT2 Others Unspecified Ratio IC50 > 531 19001116
NPT4807 Organism Bacteroides uniformis Bacteroides uniformis MIC = 0.125 ug/ml 19124664
NPT327 Organism Microsporum gypseum Microsporum gypseum IZ = 14 mm 19188377
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml 19258280
NPT2 Others Unspecified MIC90 > 32 ug/ml 19414568
NPT2 Others Unspecified MIC90 = 1 ug/ml 19651906
NPT4983 Organism Eubacterium limosum Eubacterium limosum MIC90 = 1 ug/ml 19651906
NPT2940 Organism Clostridium difficile Clostridium difficile Activity = 0 % 19651906
NPT2940 Organism Clostridium difficile Clostridium difficile Activity = 100 % 19651906
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 128000 nM 19651906
NPT2 Others Unspecified Ratio IC50 > 55.24 19651906
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 2 ug/ml 19738026
NPT2 Others Unspecified MIC90 = 1 ug/ml 19487444
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 1 ug/ml 18591275
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 98 % 20231393
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 100 % 20231393
NPT4823 Organism Prevotella buccae Prevotella buccae MIC50 = 1 ug/ml 19451299
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 0.6 ug/ml 18625769
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis EC50 = 1200 nM 18625769
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum Activity = 100 % 20921306
NPT2 Others Unspecified MIC90 > 128 ug/ml 19188393
NPT2 Others Unspecified MIC90 = 0.25 ug/ml 19188393
NPT4990 Organism Fusobacterium sp. Fusobacterium sp. MIC90 = 0.5 ug/ml 20696876
NPT2 Others Unspecified MIC = 32 ug/ml 20696876
NPT2 Others Unspecified MIC = 16 ug/ml 20696876
NPT2 Others Unspecified MIC = 8 ug/ml 20696876
NPT4823 Organism Prevotella buccae Prevotella buccae MIC = 0.5 ug/ml 20696876
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC = 0.5 ug/ml 20713672
NPT2 Others Unspecified MIC = 16 ug/ml 20713672
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC90 <= 0.125 ug/ml 20805391
NPT282 Individual Protein MAP kinase ERK2 Homo sapiens Potency = 8912.5 nM 20805391
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 1450 nM 20805391
NPT2 Others Unspecified Potency 61130.6 nM 19427200
NPT5068 Cell Line Spermatozoa Activity < 100 % 21126060
NPT5906 Organism Ruminococcus sp. Ruminococcus sp. MIC90 = 2 ug/ml DrugMatrix in vitro pharmacology data
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 2.88 ug/ml DrugMatrix in vitro pharmacology data
NPT1092 Organism Bacteroides fragilis Bacteroides fragilis MIC50 = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT4825 Organism Fusobacterium mortiferum Fusobacterium mortiferum MIC90 = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC90 = 0.25 ug/ml DrugMatrix in vitro pharmacology data
NPT4822 Organism Prevotella oralis Prevotella oralis MIC90 = 1 ug/ml DrugMatrix in vitro pharmacology data
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 2 ug/ml 10.1007/s00044-011-9696-z
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 8 ug/ml 10.1007/s00044-010-9338-x
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 5360 nM 10.1007/s00044-012-0011-4
NPT2940 Organism Clostridium difficile Clostridium difficile MIC90 = 0.5 ug/ml Open TG-GATES in vivo data: Hematology
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC50 = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT4429 Organism Prevotella loescheii Prevotella loescheii MIC = 0.5 ug/ml Open TG-GATES in vivo data: Hematology
NPT2 Others Unspecified MIC50 = 1 ug/ml Open TG-GATES in vivo data: Hematology
NPT4824 Organism Prevotella bivia Prevotella bivia MIC90 = 2 ug/ml Open TG-GATES in vivo data: Hematology
NPT2 Others Unspecified IZ = 7 mm Open TG-GATES in vivo data: Hematology
NPT88 Organism Mycobacterium tuberculosis Mycobacterium tuberculosis MIC > 128000 nM Open TG-GATES in vivo data: Hematology
NPT2645 Organism Giardia intestinalis Giardia intestinalis MIC = 1170 nM Open TG-GATES in vivo data: Biochemistry
NPT4812 Organism Parabacteroides merdae Parabacteroides merdae MIC90 = 1 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT4827 Organism Porphyromonas asaccharolytica Porphyromonas asaccharolytica MIC50 = 0.05 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT4813 Organism Bacteroides stercoris Bacteroides stercoris MIC50 = 0.5 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT2 Others Unspecified MIC = 0.032 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT2 Others Unspecified MIC = 0.064 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 5170 nM Open TG-GATES in vivo data: Biochemistry
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC > 128 ug/ml Open TG-GATES in vivo data: Biochemistry
NPT5913 Organism Prevotella denticola Prevotella denticola MIC50 = 0.5 ug/ml Open TG-GATES in vivo data: Organ Weight
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica MIC50 = 0.5 ug/ml Open TG-GATES in vivo data: Organ Weight
NPT4819 Organism Anaerococcus prevotii Anaerococcus prevotii Activity = 100 % Open TG-GATES in vivo data: Organ Weight
NPT2 Others Unspecified IC50 = 720 nM DrugMatrix in vivo data: Hematology
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC <= 0.06 ug/ml DrugMatrix in vivo data: Hematology
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC > 1 ug/ml DrugMatrix in vivo data: Hematology
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1800 nM 24126094
NPT2 Others Unspecified MIC90 = 4 ug/ml 24583356
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 0.5 ug/ml 15646539
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC50 = 1 ug/ml 15646539
NPT1359 Organism Clostridium perfringens Clostridium perfringens Activity = 7.8 % 24704617
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron MIC50 = 2 ug/ml 25280369
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC50 = 0.25 ug/ml 25682561
NPT451 Organism Helicobacter pylori Helicobacter pylori IZ = 7 mm 23691978
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC = 2 ug/ml 25735399
NPT2 Others Unspecified MIC50 <= 0.12 ug/ml 22449016
NPT2 Others Unspecified MIC90 > 32 ug/ml 9214736
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Inhibition = 99.37 % 23806110
NPT2 Others Unspecified MIC50 = 1 ug/ml 11720850
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC = 128 ug/ml 11374968
NPT2 Others Unspecified MIC = 1 ug/ml 24063567
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 0 % 24128115
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus MIC50 = 1 ug/ml 18271551
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity = 34.1 % 16989528
NPT189 Cell Line Vero Chlorocebus aethiops CC50 = 387000 nM 8864236
NPT2940 Organism Clostridium difficile Clostridium difficile MIC50 = 0.5 ug/ml 20624681
NPT2 Others Unspecified MIC50 = 0.25 ug/ml 20624681
NPT185 Organism Aspergillus flavus Aspergillus flavus IZ = 13.5 mm 14738381
NPT4992 Organism Prevotella corporis Prevotella corporis MIC = 0.25 ug/ml 21615147
NPT5913 Organism Prevotella denticola Prevotella denticola MIC = 0.25 ug/ml 21615147
NPT790 Organism Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis H37Rv GI = 99 % 22998443
NPT451 Organism Helicobacter pylori Helicobacter pylori MIC50 = 2 ug/ml 23394318
NPT2 Others Unspecified MIC50 = 1 ug/ml 24963714
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Activity = 100 % 23002419
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 0.5 ug/ml 1517737
NPT4817 Organism Finegoldia magna Finegoldia magna MIC90 = 1 ug/ml 16989519
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC50 = 1 ug/ml 26126961
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 0.21 ug/ml 10395505
NPT451 Organism Helicobacter pylori Helicobacter pylori Activity = 14 mm 10.1016/j.indcrop.2012.05.026
NPT4986 Organism Clostridium bifermentans Clostridium bifermentans MIC = 0.25 ug/ml 20545334
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC50 = 0.125 ug/ml 9804688
NPT4995 Organism Clostridium innocuum Clostridium innocuum MIC90 = 0.25 ug/ml 9804688
NPT4820 Organism Peptostreptococcus micros Parvimonas micra Activity = 0 % 17698848
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis MIC = 292000 nM 25978960
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis Inhibition = 95.98 % 25856683
NPT19 Organism Escherichia coli Escherichia coli Ratio EC50 = 20 25856683
NPT19 Organism Escherichia coli Escherichia coli Ratio EC50 = 30 25856683
NPT19 Organism Escherichia coli Escherichia coli EC50 = 500 ug/ml 25734623
NPT19 Organism Escherichia coli Escherichia coli EC50 = 750 ug/ml 25734623
NPT19 Organism Escherichia coli Escherichia coli Ratio EC50 = 3 25734623
NPT5909 Organism Propionibacterium Propionibacterium MIC50 = 32 ug/ml 19842682
NPT2 Others Unspecified MIC = 128 ug/ml 22209731
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 1430 nM 17910513
NPT4809 Organism Bacteroides caccae Bacteroides caccae Activity = 0 % 15387655
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus Activity = 0 % 10346946
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC90 = 1 ug/ml 2292689
NPT1359 Organism Clostridium perfringens Clostridium perfringens MIC90 = 1 ug/ml 12932125
NPT2 Others Unspecified MIC = 0.12 ug/ml 24900483
NPT4989 Organism Clostridium ramosum Clostridium ramosum MIC = 0.5 ug/ml 10617079
NPT4809 Organism Bacteroides caccae Bacteroides caccae Activity = 0 % 12353636
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC50 = 32 ug/ml 10.1016/j.cropro.2005.01.009
NPT4829 Organism Prevotella melaninogenica Prevotella melaninogenica Activity = 94 % 12822931
NPT1359 Organism Clostridium perfringens Clostridium perfringens Activity = 11 % 19969457
NPT2 Others Unspecified MIC50 = 16 ug/ml 10.1016/j.jssas.2011.10.002
NPT4808 Organism Bacteroides vulgatus Bacteroides vulgatus Activity = 100 % 10.1016/j.jssas.2011.10.002
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus Activity = 0 % 10.1016/j.jssas.2011.10.002
NPT4817 Organism Finegoldia magna Finegoldia magna Activity = 0 % 10.1016/j.jssas.2011.10.002
NPT4809 Organism Bacteroides caccae Bacteroides caccae MIC90 = 1 ug/ml 10.1016/j.cropro.2012.12.021
NPT1128 Organism Prevotella intermedia Prevotella intermedia MIC = 0.5 ug/ml 10.1016/j.cropro.2012.12.021
NPT3572 Organism Bacteroides thetaiotaomicron Bacteroides thetaiotaomicron Activity = 100 % 15104485
NPT1019 Organism Trichomonas vaginalis Trichomonas vaginalis IC50 = 236 nM 20553004
NPT167 Organism Propionibacterium acnes Propionibacterium acnes MIC90 = 32 ug/ml 24582402
NPT83 Cell Line MCF7 Homo sapiens IC50 > 250000 nM 7853002
NPT5908 Organism Peptostreptococcus sp. Peptostreptococcus sp. MIC50 = 0.5 ug/ml 7853002
NPT1484 Organism Fusobacterium nucleatum Fusobacterium nucleatum MIC = 0.13 ug/ml 11312925
NPT2645 Organism Giardia intestinalis Giardia intestinalis IC50 = 1160 nM 22220635
NPT4828 Organism Fusobacterium necrophorum Fusobacterium necrophorum MIC50 = 0.5 ug/ml 22409377
NPT2645 Organism Giardia intestinalis Giardia intestinalis LD50 = 1.63 ug/ml 541686
NPT3535 Organism Entamoeba histolytica HM-1:IMSS Entamoeba histolytica HM-1:IMSS IC50 = 379.8 nM 24016057
NPT29 Organism Rattus norvegicus Rattus norvegicus Inhibition = 0 % 17190444
NPT4824 Organism Prevotella bivia Prevotella bivia MIC = 0.5 ug/ml 17512094
NPT2 Others Unspecified MIC50 = 0.125 ug/ml 3572419
NPT4817 Organism Finegoldia magna Finegoldia magna MIC50 = 0.5 ug/ml 22260294
NPT2900 Organism Bifidobacterium longum Bifidobacterium longum MIC <= 0.78 ug/ml 19835393
NPT4809 Organism Bacteroides caccae Bacteroides caccae Activity = 100 % 22677314
NPT2 Others Unspecified MIC90 = 0.5 ug/ml 21640594
NPT2 Others Unspecified MIC90 = 128 ug/ml 17844994
NPT4810 Organism Bacteroides distasonis Parabacteroides distasonis MIC50 = 1 ug/ml 17844994
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 1 ug/ml 15497945
NPT4820 Organism Peptostreptococcus micros Parvimonas micra MIC90 = 0.25 ug/ml 18412396
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC90 = 1 ug/ml 23354072
NPT4811 Organism Bacteroides ovatus Bacteroides ovatus MIC90 = 2 ug/ml 12828469
NPT992 Organism Entamoeba histolytica Entamoeba histolytica IC50 = 1690 nM 17958396
NPT4821 Organism Peptostreptococcus anaerobius Peptostreptococcus anaerobius MIC50 = 0.25 ug/ml 22071302
NPT4818 Organism Peptoniphilus asaccharolyticus Peptoniphilus asaccharolyticus MIC90 = 2 ug/ml 12036352

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC332382 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.6863 Remote Similarity NPC190949
0.6176 Remote Similarity NPC237936
0.6034 Remote Similarity NPC273327
0.5812 Remote Similarity NPC326248
0.5812 Remote Similarity NPC187191
0.576 Remote Similarity NPC63433
0.568 Remote Similarity NPC313547
0.5652 Remote Similarity NPC9639
0.5649 Remote Similarity NPC109322
0.562 Remote Similarity NPC119133

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC332382 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
1.0 High Similarity NPD9134 Approved
1.0 High Similarity NPD9135 Approved
1.0 High Similarity NPD9255 Phase 2
0.9583 High Similarity NPD9195 Approved
0.8947 High Similarity NPD9190 Approved
0.8932 High Similarity NPD9182 Approved
0.87 High Similarity NPD9629 Approved
0.835 Intermediate Similarity NPD9196 Phase 2
0.8252 Intermediate Similarity NPD9502 Clinical (unspecified phase)
0.8 Intermediate Similarity NPD9345 Clinical (unspecified phase)
0.7944 Intermediate Similarity NPD613 Phase 2
0.7885 Intermediate Similarity NPD9197 Discontinued
0.783 Intermediate Similarity NPD9414 Approved
0.7822 Intermediate Similarity NPD9189 Discontinued
0.7798 Intermediate Similarity NPD9412 Discontinued
0.7664 Intermediate Similarity NPD9371 Clinical (unspecified phase)
0.7664 Intermediate Similarity NPD9415 Clinical (unspecified phase)
0.7525 Intermediate Similarity NPD8786 Approved
0.7426 Intermediate Similarity NPD8787 Clinical (unspecified phase)
0.7217 Intermediate Similarity NPD163 Approved
0.6768 Remote Similarity NPD8584 Approved
0.6308 Remote Similarity NPD9650 Phase 3
0.6281 Remote Similarity NPD757 Phase 3
0.6176 Remote Similarity NPD8186 Phase 1
0.6176 Remote Similarity NPD8185 Discontinued
0.5966 Remote Similarity NPD1816 Clinical (unspecified phase)
0.5902 Remote Similarity NPD9375 Discontinued
0.5893 Remote Similarity NPD9210 Phase 2
0.5887 Remote Similarity NPD9584 Phase 2
0.5816 Remote Similarity NPD724 Approved
0.5798 Remote Similarity NPD9626 Clinical (unspecified phase)
0.5726 Remote Similarity NPD9373 Approved
0.5703 Remote Similarity NPD307 Approved
0.5669 Remote Similarity NPD1368 Approved
0.5635 Remote Similarity NPD9374 Approved
0.562 Remote Similarity NPD9291 Approved

Structure

External Identifiers

PubChem CID   4173
ChEMBL   CHEMBL137
ZINC  

Physicochemical Properties

Molecular Weight:  171.06
ALogP:  0.2875
MLogP:  1.46
XLogP:  0.017
# Rotatable Bonds:  6
Polar Surface Area:  81.19
# H-Bond Aceptor:  3
# H-Bond Donor:  1
# Rings:  1
# Heavy Atoms:  12

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