Natural Product: NPC316292

Natural Product ID:  NPC316292
Common Name:   Citreamicin Delta
IUPAC Name:  
Synonyms:   Citreamicin Delta
Molecular Formula:   C30H21NO11
Standard InCHIKey:  YDSUTHJTPFUHBP-UHFFFAOYSA-N
Standard InCHI:  InChI=1S/C30H21NO11/c1-29(10-32)28(39)42-30(2)9-12-8-11-4-5-13-18(16(11)23(35)17(12)27(38)31(29)30)24(36)20-25(37)19-14(41-26(20)21(13)33)6-7-15(40-3)22(19)34/h4-8,32,34-35H,9-10H2,1-3H3
Canonical SMILES:  COc1ccc2c(c1O)c(=O)c1c(o2)C(=O)c2c(C1=O)c1c(cc2)cc2c(c1O)C(=O)N1C(C2)(C)OC(=O)C1(C)CO
First Find Year:  
Max Developmental Stage:  
Synthetic Gene Cluster:   ;

  Species Source

Organism ID Organism Name Taxonomy Level Family SuperKingdom Isolation Part Collection Location Collection Time Reference
NPO19824 Streptomyces vinaceus Species Streptomycetaceae Bacteria PMID[19053507]
NPO19824 Streptomyces vinaceus Species Streptomycetaceae Bacteria StreptomeDB*

  Biological Activity

Target ID Target Type Target Name Target Organism Activity Type Activity Relation Value Unit Reference
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 0.5 ug/ml 19053507
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC <= 0.5 ug/ml 19053507
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 1 ug/ml 19053507
NPT16 Organism Staphylococcus aureus Staphylococcus aureus MIC = 2 ug/ml 19053507
NPT1531 Organism Enterococcus faecium Enterococcus faecium MIC <= 0.25 ug/ml 19053507
NPT1118 Organism Streptococcus pneumoniae Streptococcus pneumoniae MIC <= 0.06 ug/ml 19053507
NPT1122 Organism Haemophilus influenzae Haemophilus influenzae MIC = 1 ug/ml 19053507
NPT3189 Organism Haemophilus parainfluenzae Haemophilus parainfluenzae MIC = 1 ug/ml 19053507
NPT19 Organism Escherichia coli Escherichia coli MIC > 128 ug/ml 19053507
NPT19 Organism Escherichia coli Escherichia coli MIC > 64 ug/ml 19053507
NPT173 Organism Klebsiella pneumoniae Klebsiella pneumoniae MIC > 64 ug/ml 19053507
NPT1121 Organism Moraxella catarrhalis Moraxella catarrhalis MIC = 4 ug/ml 19053507
NPT1248 Organism Serratia marcescens Serratia marcescens MIC > 64 ug/ml 19053507
NPT18 Organism Pseudomonas aeruginosa Pseudomonas aeruginosa MIC > 64 ug/ml 19053507
NPT2 Others Unspecified CC90 = 2.4 ug/ml 19053507
NPT3190 Cell Line NHDF Homo sapiens CC90 = 0.3 ug/ml 19053507

  Similar Natural Products in NPASS

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient

●  The left chart: Distribution of similarity level between NPC316292 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).

Similarity Score Similarity Level Natural Product ID
0.9429 High Similarity NPC315914
0.8311 Intermediate Similarity NPC185031
0.8142 Intermediate Similarity NPC211215
0.8063 Intermediate Similarity NPC170101
0.8045 Intermediate Similarity NPC478048
0.8009 Intermediate Similarity NPC478047
0.8009 Intermediate Similarity NPC180210
0.8009 Intermediate Similarity NPC321226
0.8009 Intermediate Similarity NPC314914
0.8009 Intermediate Similarity NPC478046
0.8009 Intermediate Similarity NPC328856
0.7973 Intermediate Similarity NPC284236
0.7973 Intermediate Similarity NPC316368
0.7892 Intermediate Similarity NPC82056
0.783 Intermediate Similarity NPC295436
0.782 Intermediate Similarity NPC174486
0.7804 Intermediate Similarity NPC314020
0.7804 Intermediate Similarity NPC83019
0.7757 Intermediate Similarity NPC204580
0.7723 Intermediate Similarity NPC38964
0.7717 Intermediate Similarity NPC314946
0.7709 Intermediate Similarity NPC44040
0.7661 Intermediate Similarity NPC286135
0.7619 Intermediate Similarity NPC207467
0.7556 Intermediate Similarity NPC315253
0.7547 Intermediate Similarity NPC47883
0.7535 Intermediate Similarity NPC205721
0.7534 Intermediate Similarity NPC316164
0.7524 Intermediate Similarity NPC245975
0.7512 Intermediate Similarity NPC158226
0.75 Intermediate Similarity NPC313582
0.75 Intermediate Similarity NPC119818
0.75 Intermediate Similarity NPC328700
0.75 Intermediate Similarity NPC244903
0.75 Intermediate Similarity NPC2173
0.75 Intermediate Similarity NPC473785
0.75 Intermediate Similarity NPC202771
0.7488 Intermediate Similarity NPC105591
0.7488 Intermediate Similarity NPC49667
0.7488 Intermediate Similarity NPC8127
0.7477 Intermediate Similarity NPC80472
0.7465 Intermediate Similarity NPC265795
0.7465 Intermediate Similarity NPC475996
0.7464 Intermediate Similarity NPC72696
0.7453 Intermediate Similarity NPC98546
0.7453 Intermediate Similarity NPC297807
0.7442 Intermediate Similarity NPC226725
0.7441 Intermediate Similarity NPC287243
0.743 Intermediate Similarity NPC228209
0.743 Intermediate Similarity NPC36138
0.7429 Intermediate Similarity NPC81332
0.7429 Intermediate Similarity NPC262580
0.7429 Intermediate Similarity NPC289396
0.7429 Intermediate Similarity NPC212038
0.7429 Intermediate Similarity NPC271848
0.7419 Intermediate Similarity NPC314672
0.7416 Intermediate Similarity NPC99613
0.7416 Intermediate Similarity NPC280493
0.7416 Intermediate Similarity NPC165979
0.7416 Intermediate Similarity NPC49487
0.7416 Intermediate Similarity NPC188079
0.7416 Intermediate Similarity NPC163130
0.7411 Intermediate Similarity NPC257728
0.7407 Intermediate Similarity NPC248315
0.7406 Intermediate Similarity NPC164384
0.7395 Intermediate Similarity NPC470416
0.7395 Intermediate Similarity NPC154527
0.7395 Intermediate Similarity NPC469437
0.7393 Intermediate Similarity NPC310794
0.7393 Intermediate Similarity NPC476640
0.7393 Intermediate Similarity NPC82217
0.7393 Intermediate Similarity NPC216842
0.7393 Intermediate Similarity NPC261471
0.7393 Intermediate Similarity NPC65885
0.7383 Intermediate Similarity NPC208069
0.7381 Intermediate Similarity NPC109827
0.7381 Intermediate Similarity NPC124470
0.7381 Intermediate Similarity NPC102277
0.7381 Intermediate Similarity NPC279209
0.738 Intermediate Similarity NPC475180
0.7378 Intermediate Similarity NPC46990
0.7378 Intermediate Similarity NPC153365
0.7376 Intermediate Similarity NPC151470
0.7376 Intermediate Similarity NPC201055
0.7376 Intermediate Similarity NPC254045
0.7376 Intermediate Similarity NPC64576
0.7371 Intermediate Similarity NPC477683
0.7371 Intermediate Similarity NPC246877
0.7371 Intermediate Similarity NPC477682
0.7368 Intermediate Similarity NPC243877
0.7368 Intermediate Similarity NPC295082
0.7368 Intermediate Similarity NPC473746
0.7368 Intermediate Similarity NPC260266
0.7368 Intermediate Similarity NPC234331
0.7368 Intermediate Similarity NPC469521
0.7366 Intermediate Similarity NPC314596
0.7366 Intermediate Similarity NPC257266
0.7356 Intermediate Similarity NPC26386
0.7349 Intermediate Similarity NPC162694
0.7349 Intermediate Similarity NPC8927
0.7349 Intermediate Similarity NPC182693
0.7347 Intermediate Similarity NPC131258
0.7346 Intermediate Similarity NPC121333
0.7346 Intermediate Similarity NPC54098
0.7346 Intermediate Similarity NPC230619
0.7336 Intermediate Similarity NPC183843
0.7336 Intermediate Similarity NPC324742
0.7336 Intermediate Similarity NPC212290
0.7333 Intermediate Similarity NPC473095
0.7333 Intermediate Similarity NPC473096
0.7333 Intermediate Similarity NPC315889
0.7327 Intermediate Similarity NPC240808
0.7327 Intermediate Similarity NPC269625
0.7324 Intermediate Similarity NPC216307
0.7321 Intermediate Similarity NPC29160
0.7321 Intermediate Similarity NPC37870
0.7318 Intermediate Similarity NPC215098
0.7318 Intermediate Similarity NPC73020
0.7318 Intermediate Similarity NPC14622
0.7318 Intermediate Similarity NPC124302
0.7318 Intermediate Similarity NPC70290
0.7318 Intermediate Similarity NPC46744
0.7315 Intermediate Similarity NPC208890
0.7311 Intermediate Similarity NPC37606
0.7311 Intermediate Similarity NPC327005
0.7311 Intermediate Similarity NPC154986
0.7308 Intermediate Similarity NPC470459
0.7308 Intermediate Similarity NPC270837
0.7306 Intermediate Similarity NPC60848
0.7302 Intermediate Similarity NPC97523
0.7302 Intermediate Similarity NPC6709
0.7302 Intermediate Similarity NPC18306
0.7299 Intermediate Similarity NPC101107
0.7299 Intermediate Similarity NPC78830
0.7299 Intermediate Similarity NPC218533
0.7299 Intermediate Similarity NPC476641
0.7299 Intermediate Similarity NPC17219
0.7294 Intermediate Similarity NPC94499
0.729 Intermediate Similarity NPC77179
0.729 Intermediate Similarity NPC47191
0.729 Intermediate Similarity NPC217520
0.729 Intermediate Similarity NPC35167
0.729 Intermediate Similarity NPC23553
0.729 Intermediate Similarity NPC139571
0.729 Intermediate Similarity NPC168584
0.7286 Intermediate Similarity NPC150131
0.7286 Intermediate Similarity NPC247973
0.7286 Intermediate Similarity NPC473094
0.7286 Intermediate Similarity NPC283041
0.7286 Intermediate Similarity NPC14662
0.7285 Intermediate Similarity NPC207239
0.7285 Intermediate Similarity NPC42286
0.7277 Intermediate Similarity NPC99591
0.7277 Intermediate Similarity NPC186800
0.7277 Intermediate Similarity NPC470667
0.7277 Intermediate Similarity NPC314941
0.7277 Intermediate Similarity NPC227906
0.7273 Intermediate Similarity NPC239752
0.7273 Intermediate Similarity NPC275780
0.7273 Intermediate Similarity NPC471788
0.7273 Intermediate Similarity NPC326520
0.7273 Intermediate Similarity NPC24228
0.7273 Intermediate Similarity NPC470457
0.7273 Intermediate Similarity NPC472450
0.7269 Intermediate Similarity NPC475656
0.7269 Intermediate Similarity NPC150977
0.7269 Intermediate Similarity NPC475148
0.7264 Intermediate Similarity NPC473113
0.7264 Intermediate Similarity NPC260263
0.7264 Intermediate Similarity NPC4200
0.7264 Intermediate Similarity NPC247964
0.726 Intermediate Similarity NPC294965
0.7256 Intermediate Similarity NPC113446
0.7256 Intermediate Similarity NPC185275
0.7256 Intermediate Similarity NPC114257
0.7256 Intermediate Similarity NPC476273
0.7256 Intermediate Similarity NPC153578
0.7256 Intermediate Similarity NPC277710
0.7256 Intermediate Similarity NPC299149
0.7252 Intermediate Similarity NPC109403
0.7252 Intermediate Similarity NPC226652
0.7252 Intermediate Similarity NPC314738
0.7252 Intermediate Similarity NPC314100
0.7252 Intermediate Similarity NPC72788
0.7252 Intermediate Similarity NPC120671
0.7252 Intermediate Similarity NPC261012
0.7252 Intermediate Similarity NPC3474
0.7251 Intermediate Similarity NPC177480
0.7251 Intermediate Similarity NPC475805
0.7251 Intermediate Similarity NPC242395
0.7251 Intermediate Similarity NPC476637
0.7251 Intermediate Similarity NPC152477
0.7248 Intermediate Similarity NPC73929
0.7248 Intermediate Similarity NPC139683
0.7248 Intermediate Similarity NPC47905
0.7246 Intermediate Similarity NPC13249
0.7243 Intermediate Similarity NPC154741
0.7243 Intermediate Similarity NPC472992
0.7243 Intermediate Similarity NPC198324
0.7243 Intermediate Similarity NPC296018

  Similar Clinical/Approved Drugs

Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.

●  The left chart: Distribution of similarity level between NPC316292 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).

Similarity Score Similarity Level Drug ID Developmental Stage
0.7731 Intermediate Similarity NPD7501 Clinical (unspecified phase)
0.7709 Intermediate Similarity NPD8155 Clinical (unspecified phase)
0.766 Intermediate Similarity NPD7048 Phase 3
0.7632 Intermediate Similarity NPD7907 Approved
0.7568 Intermediate Similarity NPD7701 Phase 2
0.75 Intermediate Similarity NPD5005 Approved
0.75 Intermediate Similarity NPD5006 Approved
0.7467 Intermediate Similarity NPD4665 Approved
0.7467 Intermediate Similarity NPD4111 Phase 1
0.7443 Intermediate Similarity NPD8285 Discontinued
0.7414 Intermediate Similarity NPD5619 Clinical (unspecified phase)
0.7411 Intermediate Similarity NPD7585 Approved
0.7385 Intermediate Similarity NPD7667 Clinical (unspecified phase)
0.7376 Intermediate Similarity NPD2493 Approved
0.7376 Intermediate Similarity NPD2494 Approved
0.7376 Intermediate Similarity NPD3452 Approved
0.7376 Intermediate Similarity NPD3450 Approved
0.7371 Intermediate Similarity NPD6997 Phase 2
0.7366 Intermediate Similarity NPD7583 Approved
0.7366 Intermediate Similarity NPD7584 Approved
0.7347 Intermediate Similarity NPD8152 Approved
0.7347 Intermediate Similarity NPD8153 Approved
0.7333 Intermediate Similarity NPD5844 Phase 1
0.7318 Intermediate Similarity NPD4420 Approved
0.7277 Intermediate Similarity NPD4582 Approved
0.7277 Intermediate Similarity NPD4583 Approved
0.7277 Intermediate Similarity NPD8320 Phase 1
0.7277 Intermediate Similarity NPD8319 Approved
0.7269 Intermediate Similarity NPD7875 Clinical (unspecified phase)
0.7269 Intermediate Similarity NPD7874 Approved
0.726 Intermediate Similarity NPD6232 Discontinued
0.7252 Intermediate Similarity NPD6780 Approved
0.7252 Intermediate Similarity NPD6781 Approved
0.7252 Intermediate Similarity NPD6777 Approved
0.7252 Intermediate Similarity NPD6776 Approved
0.7252 Intermediate Similarity NPD6778 Approved
0.7252 Intermediate Similarity NPD6779 Approved
0.7252 Intermediate Similarity NPD6782 Approved
0.7238 Intermediate Similarity NPD7473 Discontinued
0.7232 Intermediate Similarity NPD4002 Approved
0.7232 Intermediate Similarity NPD4004 Approved
0.7229 Intermediate Similarity NPD8404 Phase 2
0.7212 Intermediate Similarity NPD6973 Clinical (unspecified phase)
0.72 Intermediate Similarity NPD7870 Phase 2
0.72 Intermediate Similarity NPD7871 Phase 2
0.7196 Intermediate Similarity NPD4338 Clinical (unspecified phase)
0.7196 Intermediate Similarity NPD4419 Clinical (unspecified phase)
0.7195 Intermediate Similarity NPD2974 Approved
0.7195 Intermediate Similarity NPD2975 Approved
0.7195 Intermediate Similarity NPD2973 Approved
0.719 Intermediate Similarity NPD6166 Phase 2
0.719 Intermediate Similarity NPD6167 Clinical (unspecified phase)
0.719 Intermediate Similarity NPD6168 Clinical (unspecified phase)
0.7169 Intermediate Similarity NPD7879 Clinical (unspecified phase)
0.7162 Intermediate Similarity NPD7782 Clinical (unspecified phase)
0.7162 Intermediate Similarity NPD5676 Approved
0.7162 Intermediate Similarity NPD7783 Phase 2
0.7156 Intermediate Similarity NPD7696 Phase 3
0.7156 Intermediate Similarity NPD7697 Approved
0.7156 Intermediate Similarity NPD7435 Discontinued
0.7156 Intermediate Similarity NPD7698 Approved
0.7149 Intermediate Similarity NPD8151 Discontinued
0.7143 Intermediate Similarity NPD5242 Approved
0.7136 Intermediate Similarity NPD6213 Phase 3
0.7136 Intermediate Similarity NPD6212 Phase 3
0.7136 Intermediate Similarity NPD6214 Clinical (unspecified phase)
0.7123 Intermediate Similarity NPD3808 Clinical (unspecified phase)
0.7123 Intermediate Similarity NPD7177 Discontinued
0.7111 Intermediate Similarity NPD3057 Approved
0.7101 Intermediate Similarity NPD8059 Phase 3
0.7101 Intermediate Similarity NPD8058 Clinical (unspecified phase)
0.7098 Intermediate Similarity NPD4580 Approved
0.7078 Intermediate Similarity NPD8397 Clinical (unspecified phase)
0.7064 Intermediate Similarity NPD8150 Discontinued
0.7045 Intermediate Similarity NPD2490 Approved
0.7045 Intermediate Similarity NPD2488 Approved
0.7035 Intermediate Similarity NPD2972 Approved
0.7035 Intermediate Similarity NPD3448 Approved
0.7035 Intermediate Similarity NPD2491 Approved
0.7035 Intermediate Similarity NPD3533 Approved
0.7027 Intermediate Similarity NPD6534 Approved
0.7027 Intermediate Similarity NPD6535 Approved
0.7022 Intermediate Similarity NPD4107 Approved
0.7021 Intermediate Similarity NPD2899 Discontinued
0.7019 Intermediate Similarity NPD3882 Suspended
0.7014 Intermediate Similarity NPD5710 Approved
0.7014 Intermediate Similarity NPD5711 Approved
0.7013 Intermediate Similarity NPD7801 Approved
0.7012 Intermediate Similarity NPD8067 Phase 3
0.6971 Remote Similarity NPD5402 Approved
0.6971 Remote Similarity NPD3817 Phase 2
0.6969 Remote Similarity NPD8461 Discontinued
0.6966 Remote Similarity NPD7047 Phase 3
0.6963 Remote Similarity NPD3818 Discontinued
0.6944 Remote Similarity NPD7993 Clinical (unspecified phase)
0.6944 Remote Similarity NPD6797 Phase 2
0.6943 Remote Similarity NPD7211 Clinical (unspecified phase)
0.6938 Remote Similarity NPD4868 Clinical (unspecified phase)
0.6933 Remote Similarity NPD7700 Phase 2
0.6933 Remote Similarity NPD7699 Phase 2
0.6929 Remote Similarity NPD7654 Discontinued
0.6927 Remote Similarity NPD3534 Clinical (unspecified phase)
0.6923 Remote Similarity NPD2801 Approved
0.6919 Remote Similarity NPD5494 Approved
0.6916 Remote Similarity NPD4482 Phase 3
0.6912 Remote Similarity NPD7251 Discontinued
0.6905 Remote Similarity NPD7075 Discontinued
0.6887 Remote Similarity NPD6959 Discontinued
0.6881 Remote Similarity NPD7808 Phase 3
0.6875 Remote Similarity NPD4413 Clinical (unspecified phase)
0.687 Remote Similarity NPD4846 Phase 2
0.6852 Remote Similarity NPD6020 Phase 2
0.6852 Remote Similarity NPD7054 Approved
0.6844 Remote Similarity NPD4361 Phase 2
0.6844 Remote Similarity NPD4362 Clinical (unspecified phase)
0.6842 Remote Similarity NPD2393 Clinical (unspecified phase)
0.6835 Remote Similarity NPD6559 Discontinued
0.6835 Remote Similarity NPD7038 Approved
0.6835 Remote Similarity NPD7039 Approved
0.6828 Remote Similarity NPD7237 Clinical (unspecified phase)
0.6828 Remote Similarity NPD7811 Phase 3
0.6828 Remote Similarity NPD7810 Phase 3
0.682 Remote Similarity NPD7074 Phase 3
0.682 Remote Similarity NPD7472 Approved
0.6818 Remote Similarity NPD8053 Approved
0.6818 Remote Similarity NPD8054 Approved
0.6812 Remote Similarity NPD6823 Phase 2
0.6806 Remote Similarity NPD3751 Discontinued
0.6804 Remote Similarity NPD7549 Discontinued
0.68 Remote Similarity NPD4360 Phase 2
0.68 Remote Similarity NPD4363 Phase 3
0.6798 Remote Similarity NPD5457 Discontinued
0.6794 Remote Similarity NPD6801 Discontinued
0.6794 Remote Similarity NPD1934 Approved
0.6783 Remote Similarity NPD7597 Clinical (unspecified phase)
0.6774 Remote Similarity NPD7804 Clinical (unspecified phase)
0.6773 Remote Similarity NPD8312 Approved
0.6773 Remote Similarity NPD2971 Approved
0.6773 Remote Similarity NPD2968 Approved
0.6773 Remote Similarity NPD8313 Approved
0.6762 Remote Similarity NPD7819 Suspended
0.6762 Remote Similarity NPD1465 Phase 2
0.6762 Remote Similarity NPD7096 Clinical (unspecified phase)
0.6753 Remote Similarity NPD4040 Phase 1
0.675 Remote Similarity NPD8366 Approved
0.6749 Remote Similarity NPD8469 Approved
0.6748 Remote Similarity NPD6625 Approved
0.6732 Remote Similarity NPD8367 Approved
0.6729 Remote Similarity NPD1247 Approved
0.6728 Remote Similarity NPD5940 Clinical (unspecified phase)
0.6726 Remote Similarity NPD7906 Approved
0.6714 Remote Similarity NPD919 Approved
0.6713 Remote Similarity NPD7852 Clinical (unspecified phase)
0.6712 Remote Similarity NPD8055 Clinical (unspecified phase)
0.6708 Remote Similarity NPD8491 Approved
0.6699 Remote Similarity NPD4380 Phase 2
0.6697 Remote Similarity NPD3050 Clinical (unspecified phase)
0.6693 Remote Similarity NPD8492 Approved
0.6682 Remote Similarity NPD3446 Phase 1
0.6682 Remote Similarity NPD3863 Clinical (unspecified phase)
0.6667 Remote Similarity NPD7090 Clinical (unspecified phase)
0.6667 Remote Similarity NPD7411 Suspended
0.6667 Remote Similarity NPD3749 Approved
0.6667 Remote Similarity NPD3926 Phase 2
0.6652 Remote Similarity NPD8161 Suspended
0.6651 Remote Similarity NPD3226 Approved
0.6651 Remote Similarity NPD7893 Clinical (unspecified phase)
0.6635 Remote Similarity NPD5403 Approved
0.6635 Remote Similarity NPD6844 Discontinued
0.6619 Remote Similarity NPD6599 Discontinued
0.6613 Remote Similarity NPD7942 Clinical (unspecified phase)
0.6608 Remote Similarity NPD6181 Discontinued
0.6607 Remote Similarity NPD4663 Approved
0.6607 Remote Similarity NPD5038 Approved
0.6607 Remote Similarity NPD8434 Phase 2
0.6607 Remote Similarity NPD5037 Approved
0.6594 Remote Similarity NPD8485 Approved
0.6593 Remote Similarity NPD5525 Clinical (unspecified phase)
0.6592 Remote Similarity NPD6851 Approved
0.6592 Remote Similarity NPD6853 Approved
0.6591 Remote Similarity NPD5441 Clinical (unspecified phase)
0.659 Remote Similarity NPD7184 Clinical (unspecified phase)
0.6589 Remote Similarity NPD4381 Clinical (unspecified phase)
0.6589 Remote Similarity NPD8005 Clinical (unspecified phase)
0.6588 Remote Similarity NPD5890 Approved
0.6588 Remote Similarity NPD5889 Approved
0.6587 Remote Similarity NPD1512 Approved
0.6583 Remote Similarity NPD5980 Discovery
0.6578 Remote Similarity NPD7291 Discontinued
0.6575 Remote Similarity NPD7228 Approved
0.6571 Remote Similarity NPD7224 Discontinued
0.6571 Remote Similarity NPD7223 Discontinued
0.6569 Remote Similarity NPD7930 Approved
0.6567 Remote Similarity NPD7497 Discontinued
0.6562 Remote Similarity NPD5036 Approved
0.6561 Remote Similarity NPD1483 Discontinued
0.656 Remote Similarity NPD3451 Clinical (unspecified phase)
0.656 Remote Similarity NPD7784 Clinical (unspecified phase)
0.656 Remote Similarity NPD4575 Clinical (unspecified phase)
0.6555 Remote Similarity NPD7827 Phase 1

Structure

External Identifiers

PubChem CID   25147605
ChEMBL   CHEMBL447712
ZINC  

Physicochemical Properties

Molecular Weight:  571.11
ALogP:  -2.9788
MLogP:  3.44
XLogP:  1.329
# Rotatable Bonds:  8
Polar Surface Area:  176.97
# H-Bond Aceptor:  8
# H-Bond Donor:  3
# Rings:  7
# Heavy Atoms:  42

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