Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC277382 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
1.0 | High Similarity | NPC171978 |
0.9474 | High Similarity | NPC469713 |
0.8919 | High Similarity | NPC195109 |
0.7317 | Intermediate Similarity | NPC34873 |
0.7317 | Intermediate Similarity | NPC40434 |
0.6744 | Remote Similarity | NPC15934 |
0.6585 | Remote Similarity | NPC58957 |
0.6522 | Remote Similarity | NPC252978 |
0.65 | Remote Similarity | NPC197356 |
0.65 | Remote Similarity | NPC63121 |
0.6383 | Remote Similarity | NPC108195 |
0.6364 | Remote Similarity | NPC182840 |
0.6364 | Remote Similarity | NPC103213 |
0.6364 | Remote Similarity | NPC255042 |
0.6364 | Remote Similarity | NPC29091 |
0.6341 | Remote Similarity | NPC250734 |
0.6304 | Remote Similarity | NPC206906 |
0.6304 | Remote Similarity | NPC304151 |
0.625 | Remote Similarity | NPC160628 |
0.625 | Remote Similarity | NPC140501 |
0.625 | Remote Similarity | NPC329424 |
0.625 | Remote Similarity | NPC221379 |
0.625 | Remote Similarity | NPC276825 |
0.625 | Remote Similarity | NPC76976 |
0.6222 | Remote Similarity | NPC103236 |
0.6222 | Remote Similarity | NPC27444 |
0.6222 | Remote Similarity | NPC123357 |
0.6222 | Remote Similarity | NPC329762 |
0.62 | Remote Similarity | NPC302310 |
0.617 | Remote Similarity | NPC116934 |
0.617 | Remote Similarity | NPC270796 |
0.6136 | Remote Similarity | NPC226511 |
0.6087 | Remote Similarity | NPC33489 |
0.6087 | Remote Similarity | NPC269823 |
0.6078 | Remote Similarity | NPC291437 |
0.6078 | Remote Similarity | NPC328784 |
0.6078 | Remote Similarity | NPC474460 |
0.6047 | Remote Similarity | NPC75204 |
0.6042 | Remote Similarity | NPC138935 |
0.6 | Remote Similarity | NPC33761 |
0.6 | Remote Similarity | NPC318549 |
0.5962 | Remote Similarity | NPC71053 |
0.5962 | Remote Similarity | NPC151782 |
0.5962 | Remote Similarity | NPC59408 |
0.5957 | Remote Similarity | NPC187922 |
0.5957 | Remote Similarity | NPC68889 |
0.5957 | Remote Similarity | NPC67761 |
0.5957 | Remote Similarity | NPC180871 |
0.5957 | Remote Similarity | NPC88079 |
0.5957 | Remote Similarity | NPC287397 |
0.5957 | Remote Similarity | NPC298710 |
0.5957 | Remote Similarity | NPC256766 |
0.5957 | Remote Similarity | NPC67920 |
0.5957 | Remote Similarity | NPC149668 |
0.5957 | Remote Similarity | NPC108494 |
0.5957 | Remote Similarity | NPC213538 |
0.5957 | Remote Similarity | NPC194586 |
0.5957 | Remote Similarity | NPC51758 |
0.5957 | Remote Similarity | NPC209279 |
0.5957 | Remote Similarity | NPC57923 |
0.5957 | Remote Similarity | NPC208936 |
0.5918 | Remote Similarity | NPC24824 |
0.5918 | Remote Similarity | NPC165651 |
0.5918 | Remote Similarity | NPC210560 |
0.5918 | Remote Similarity | NPC269074 |
0.5918 | Remote Similarity | NPC117572 |
0.5909 | Remote Similarity | NPC279300 |
0.5897 | Remote Similarity | NPC138325 |
0.5882 | Remote Similarity | NPC98284 |
0.5882 | Remote Similarity | NPC31194 |
0.5882 | Remote Similarity | NPC85079 |
0.5882 | Remote Similarity | NPC153538 |
0.5882 | Remote Similarity | NPC207815 |
0.5882 | Remote Similarity | NPC248884 |
0.587 | Remote Similarity | NPC323278 |
0.587 | Remote Similarity | NPC12319 |
0.587 | Remote Similarity | NPC56917 |
0.587 | Remote Similarity | NPC18205 |
0.5849 | Remote Similarity | NPC35756 |
0.5814 | Remote Similarity | NPC72258 |
0.58 | Remote Similarity | NPC19834 |
0.58 | Remote Similarity | NPC124183 |
0.58 | Remote Similarity | NPC157096 |
0.58 | Remote Similarity | NPC55063 |
0.58 | Remote Similarity | NPC35141 |
0.58 | Remote Similarity | NPC180575 |
0.5778 | Remote Similarity | NPC155880 |
0.5778 | Remote Similarity | NPC92863 |
0.5769 | Remote Similarity | NPC225974 |
0.5769 | Remote Similarity | NPC288381 |
0.5769 | Remote Similarity | NPC20934 |
0.5769 | Remote Similarity | NPC72699 |
0.575 | Remote Similarity | NPC34671 |
0.575 | Remote Similarity | NPC138113 |
0.5745 | Remote Similarity | NPC188596 |
0.5741 | Remote Similarity | NPC284224 |
0.5741 | Remote Similarity | NPC475723 |
0.5714 | Remote Similarity | NPC101616 |
0.5714 | Remote Similarity | NPC12907 |
0.5686 | Remote Similarity | NPC91495 |
0.5682 | Remote Similarity | NPC277288 |
0.5682 | Remote Similarity | NPC79544 |
0.5682 | Remote Similarity | NPC213767 |
0.566 | Remote Similarity | NPC129263 |
0.566 | Remote Similarity | NPC55383 |
0.566 | Remote Similarity | NPC474495 |
0.566 | Remote Similarity | NPC93639 |
0.566 | Remote Similarity | NPC473672 |
0.566 | Remote Similarity | NPC29234 |
0.5652 | Remote Similarity | NPC217923 |
0.5652 | Remote Similarity | NPC57011 |
0.5636 | Remote Similarity | NPC49059 |
0.5636 | Remote Similarity | NPC110732 |
0.5636 | Remote Similarity | NPC300121 |
0.5636 | Remote Similarity | NPC256209 |
0.5636 | Remote Similarity | NPC137538 |
0.5625 | Remote Similarity | NPC46248 |
0.5625 | Remote Similarity | NPC249801 |
0.5614 | Remote Similarity | NPC323436 |
0.561 | Remote Similarity | NPC60288 |
0.56 | Remote Similarity | NPC47946 |
0.56 | Remote Similarity | NPC474362 |
0.56 | Remote Similarity | NPC474202 |
0.56 | Remote Similarity | NPC26600 |
0.56 | Remote Similarity | NPC239754 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC277382 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.6383 | Remote Similarity | NPD6096 | Approved |
0.6383 | Remote Similarity | NPD6097 | Approved |
0.625 | Remote Similarity | NPD4265 | Approved |
0.617 | Remote Similarity | NPD5326 | Phase 3 |
0.6 | Remote Similarity | NPD5343 | Approved |
0.5918 | Remote Similarity | NPD39 | Approved |
0.5918 | Remote Similarity | NPD4222 | Approved |
0.5769 | Remote Similarity | NPD2268 | Discontinued |
0.56 | Remote Similarity | NPD3174 | Discontinued |
PubChem CID   | 10354007 |
ChEMBL   | CHEMBL460230 |
ZINC   |
Molecular Weight:   | 234.09 |
ALogP:   | 0.2314 |
MLogP:   | 2.01 |
XLogP:   | 2.125 |
# Rotatable Bonds:   | 10 |
Polar Surface Area:   | 71.98 |
# H-Bond Aceptor:   | 4 |
# H-Bond Donor:   | 1 |
# Rings:   | 0 |
# Heavy Atoms:   | 15 |