Target ID | Target Type | Target Name | Target Organism | Activity Type | Activity Relation | Value | Unit | Reference |
---|---|---|---|---|---|---|---|---|
NPT153 | Individual Protein | Androgen Receptor | Homo sapiens | Potency | 432.8 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 54482.7 | nM | PubChem BioAssay data set | ||
NPT152 | Individual Protein | Nuclear factor erythroid 2-related factor 2 | Homo sapiens | Potency | 43277.1 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 61644.8 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 27306 | nM | PubChem BioAssay data set | ||
NPT162 | Individual Protein | Heat shock protein beta-1 | Homo sapiens | Potency | 61644.8 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 48966.2 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 48557.7 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 61130.6 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 54941 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 43641.2 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 24336.5 | nM | PubChem BioAssay data set | ||
NPT74 | Individual Protein | Proto-oncogene c-JUN | Homo sapiens | Potency | 61644.8 | nM | PubChem BioAssay data set | |
NPT2 | Others | Unspecified | Potency | 19493.8 | nM | PubChem BioAssay data set | ||
NPT2 | Others | Unspecified | Potency | 68589.6 | nM | PubChem BioAssay data set |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules. Tc lies between [0, 1] where '1' indicates the highest similarity. What is Tanimoto coefficient
●  The left chart: Distribution of similarity level between NPC234597 and all remaining natural products in the NPASS database.
●  The right table: Most similar natural products (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Natural Product ID |
---|---|---|
0.8958 | High Similarity | NPC289388 |
0.8776 | High Similarity | NPC244452 |
0.86 | High Similarity | NPC170167 |
0.8235 | Intermediate Similarity | NPC216407 |
0.7755 | Intermediate Similarity | NPC210560 |
0.7755 | Intermediate Similarity | NPC24824 |
0.7755 | Intermediate Similarity | NPC165651 |
0.7647 | Intermediate Similarity | NPC91765 |
0.7551 | Intermediate Similarity | NPC12907 |
0.75 | Intermediate Similarity | NPC142103 |
0.7321 | Intermediate Similarity | NPC252860 |
0.7321 | Intermediate Similarity | NPC141699 |
0.7255 | Intermediate Similarity | NPC276009 |
0.7255 | Intermediate Similarity | NPC22098 |
0.7255 | Intermediate Similarity | NPC195246 |
0.7193 | Intermediate Similarity | NPC165808 |
0.7119 | Intermediate Similarity | NPC19241 |
0.7018 | Intermediate Similarity | NPC96663 |
0.7 | Intermediate Similarity | NPC106819 |
0.6981 | Remote Similarity | NPC207815 |
0.6842 | Remote Similarity | NPC223604 |
0.6774 | Remote Similarity | NPC34883 |
0.6774 | Remote Similarity | NPC469723 |
0.6731 | Remote Similarity | NPC47946 |
0.6731 | Remote Similarity | NPC26600 |
0.6727 | Remote Similarity | NPC148056 |
0.6727 | Remote Similarity | NPC48162 |
0.6719 | Remote Similarity | NPC472266 |
0.6667 | Remote Similarity | NPC62755 |
0.6667 | Remote Similarity | NPC15912 |
0.6667 | Remote Similarity | NPC163345 |
0.6667 | Remote Similarity | NPC135698 |
0.6667 | Remote Similarity | NPC98284 |
0.6613 | Remote Similarity | NPC217940 |
0.6607 | Remote Similarity | NPC151919 |
0.6607 | Remote Similarity | NPC294358 |
0.6607 | Remote Similarity | NPC40417 |
0.6604 | Remote Similarity | NPC197467 |
0.66 | Remote Similarity | NPC188596 |
0.6552 | Remote Similarity | NPC67367 |
0.6552 | Remote Similarity | NPC477984 |
0.6552 | Remote Similarity | NPC148163 |
0.6552 | Remote Similarity | NPC130209 |
0.6552 | Remote Similarity | NPC148216 |
0.6545 | Remote Similarity | NPC27264 |
0.6545 | Remote Similarity | NPC329773 |
0.6515 | Remote Similarity | NPC144511 |
0.6515 | Remote Similarity | NPC22301 |
0.6515 | Remote Similarity | NPC329656 |
0.6515 | Remote Similarity | NPC269841 |
0.6515 | Remote Similarity | NPC296522 |
0.6515 | Remote Similarity | NPC101622 |
0.65 | Remote Similarity | NPC155025 |
0.65 | Remote Similarity | NPC226848 |
0.65 | Remote Similarity | NPC240206 |
0.6491 | Remote Similarity | NPC165755 |
0.6471 | Remote Similarity | NPC187922 |
0.6429 | Remote Similarity | NPC214584 |
0.6429 | Remote Similarity | NPC26906 |
0.6418 | Remote Similarity | NPC472017 |
0.6418 | Remote Similarity | NPC4299 |
0.6418 | Remote Similarity | NPC475310 |
0.6418 | Remote Similarity | NPC472955 |
0.6415 | Remote Similarity | NPC87439 |
0.6415 | Remote Similarity | NPC270706 |
0.6406 | Remote Similarity | NPC220766 |
0.64 | Remote Similarity | NPC12319 |
0.64 | Remote Similarity | NPC18205 |
0.6393 | Remote Similarity | NPC83838 |
0.6393 | Remote Similarity | NPC143810 |
0.6393 | Remote Similarity | NPC122239 |
0.6393 | Remote Similarity | NPC475931 |
0.6379 | Remote Similarity | NPC95581 |
0.6379 | Remote Similarity | NPC137538 |
0.6364 | Remote Similarity | NPC470040 |
0.6364 | Remote Similarity | NPC276290 |
0.6349 | Remote Similarity | NPC155849 |
0.6349 | Remote Similarity | NPC474658 |
0.6346 | Remote Similarity | NPC269862 |
0.6327 | Remote Similarity | NPC316546 |
0.6324 | Remote Similarity | NPC477087 |
0.6324 | Remote Similarity | NPC163003 |
0.6324 | Remote Similarity | NPC477084 |
0.6324 | Remote Similarity | NPC477086 |
0.6324 | Remote Similarity | NPC472254 |
0.6324 | Remote Similarity | NPC129665 |
0.6316 | Remote Similarity | NPC306195 |
0.6316 | Remote Similarity | NPC157781 |
0.6316 | Remote Similarity | NPC179169 |
0.6316 | Remote Similarity | NPC181255 |
0.6316 | Remote Similarity | NPC35519 |
0.6308 | Remote Similarity | NPC126899 |
0.6308 | Remote Similarity | NPC477982 |
0.6308 | Remote Similarity | NPC304665 |
0.6308 | Remote Similarity | NPC154728 |
0.6308 | Remote Similarity | NPC191233 |
0.6296 | Remote Similarity | NPC128280 |
0.6296 | Remote Similarity | NPC262558 |
0.6296 | Remote Similarity | NPC8610 |
0.629 | Remote Similarity | NPC99487 |
0.629 | Remote Similarity | NPC66020 |
0.629 | Remote Similarity | NPC240506 |
0.629 | Remote Similarity | NPC127824 |
0.6271 | Remote Similarity | NPC232247 |
0.6271 | Remote Similarity | NPC10316 |
0.6271 | Remote Similarity | NPC28779 |
0.6271 | Remote Similarity | NPC281590 |
0.6271 | Remote Similarity | NPC227135 |
0.6271 | Remote Similarity | NPC251666 |
0.6271 | Remote Similarity | NPC200845 |
0.6271 | Remote Similarity | NPC46151 |
0.6271 | Remote Similarity | NPC223677 |
0.6271 | Remote Similarity | NPC128061 |
0.6271 | Remote Similarity | NPC52264 |
0.6269 | Remote Similarity | NPC199557 |
0.6269 | Remote Similarity | NPC232812 |
0.6269 | Remote Similarity | NPC107130 |
0.6269 | Remote Similarity | NPC261398 |
0.625 | Remote Similarity | NPC282119 |
0.625 | Remote Similarity | NPC26960 |
0.625 | Remote Similarity | NPC236338 |
0.625 | Remote Similarity | NPC182102 |
0.625 | Remote Similarity | NPC92224 |
0.625 | Remote Similarity | NPC329698 |
0.625 | Remote Similarity | NPC234767 |
0.6232 | Remote Similarity | NPC470237 |
0.6232 | Remote Similarity | NPC472018 |
0.6232 | Remote Similarity | NPC58956 |
0.6232 | Remote Similarity | NPC135703 |
0.6232 | Remote Similarity | NPC269206 |
0.6232 | Remote Similarity | NPC295633 |
0.6232 | Remote Similarity | NPC477085 |
0.6232 | Remote Similarity | NPC474543 |
0.6232 | Remote Similarity | NPC238425 |
0.623 | Remote Similarity | NPC329819 |
0.6226 | Remote Similarity | NPC114841 |
0.6212 | Remote Similarity | NPC473357 |
0.6212 | Remote Similarity | NPC472875 |
0.6212 | Remote Similarity | NPC193029 |
0.6212 | Remote Similarity | NPC194871 |
0.6207 | Remote Similarity | NPC39633 |
0.6207 | Remote Similarity | NPC139545 |
0.6207 | Remote Similarity | NPC71761 |
0.6207 | Remote Similarity | NPC309606 |
0.6197 | Remote Similarity | NPC472959 |
0.619 | Remote Similarity | NPC294304 |
0.619 | Remote Similarity | NPC64971 |
0.619 | Remote Similarity | NPC228574 |
0.619 | Remote Similarity | NPC207007 |
0.619 | Remote Similarity | NPC149682 |
0.619 | Remote Similarity | NPC68679 |
0.619 | Remote Similarity | NPC321867 |
0.6176 | Remote Similarity | NPC469660 |
0.6176 | Remote Similarity | NPC37929 |
0.6176 | Remote Similarity | NPC318766 |
0.6176 | Remote Similarity | NPC64234 |
0.6176 | Remote Similarity | NPC69462 |
0.6167 | Remote Similarity | NPC473936 |
0.6167 | Remote Similarity | NPC48891 |
0.6154 | Remote Similarity | NPC470688 |
0.6143 | Remote Similarity | NPC472966 |
0.6143 | Remote Similarity | NPC474551 |
0.6143 | Remote Similarity | NPC117746 |
0.6143 | Remote Similarity | NPC15499 |
0.6143 | Remote Similarity | NPC474758 |
0.6143 | Remote Similarity | NPC259599 |
0.6143 | Remote Similarity | NPC476355 |
0.6143 | Remote Similarity | NPC140287 |
0.6143 | Remote Similarity | NPC294434 |
0.614 | Remote Similarity | NPC244038 |
0.614 | Remote Similarity | NPC251335 |
0.6129 | Remote Similarity | NPC278202 |
0.6122 | Remote Similarity | NPC190810 |
0.6122 | Remote Similarity | NPC34764 |
0.6122 | Remote Similarity | NPC76145 |
0.6119 | Remote Similarity | NPC310210 |
0.6119 | Remote Similarity | NPC470256 |
0.6111 | Remote Similarity | NPC140501 |
0.6102 | Remote Similarity | NPC100809 |
0.6102 | Remote Similarity | NPC209431 |
0.6094 | Remote Similarity | NPC211291 |
0.6094 | Remote Similarity | NPC473508 |
0.6094 | Remote Similarity | NPC322457 |
0.6094 | Remote Similarity | NPC133368 |
0.6087 | Remote Similarity | NPC206088 |
0.6087 | Remote Similarity | NPC126061 |
0.6078 | Remote Similarity | NPC123357 |
0.6071 | Remote Similarity | NPC149821 |
0.6071 | Remote Similarity | NPC5413 |
0.6066 | Remote Similarity | NPC52012 |
0.6061 | Remote Similarity | NPC315115 |
0.6056 | Remote Similarity | NPC475861 |
0.6056 | Remote Similarity | NPC226669 |
0.6056 | Remote Similarity | NPC155587 |
0.6056 | Remote Similarity | NPC324762 |
0.6056 | Remote Similarity | NPC329852 |
0.6056 | Remote Similarity | NPC113639 |
0.6056 | Remote Similarity | NPC138408 |
0.6056 | Remote Similarity | NPC255060 |
0.6056 | Remote Similarity | NPC193351 |
Similarity level is defined by Tanimoto coefficient (Tc) between two molecules.
●  The left chart: Distribution of similarity level between NPC234597 and all drugs/candidates.
●  The right table: Most similar clinical/approved drugs (Tc>=0.56 or Top200).
Similarity Score | Similarity Level | Drug ID | Developmental Stage |
---|---|---|---|
0.6667 | Remote Similarity | NPD2685 | Clinical (unspecified phase) |
0.6552 | Remote Similarity | NPD342 | Phase 1 |
0.6481 | Remote Similarity | NPD5343 | Approved |
0.6429 | Remote Similarity | NPD6927 | Phase 3 |
0.6415 | Remote Similarity | NPD3174 | Discontinued |
0.6226 | Remote Similarity | NPD6097 | Approved |
0.6226 | Remote Similarity | NPD6096 | Approved |
0.619 | Remote Similarity | NPD368 | Approved |
0.6122 | Remote Similarity | NPD319 | Phase 1 |
0.6111 | Remote Similarity | NPD4265 | Approved |
0.6071 | Remote Similarity | NPD3173 | Approved |
0.6 | Remote Similarity | NPD5325 | Clinical (unspecified phase) |
0.5862 | Remote Similarity | NPD28 | Approved |
0.5862 | Remote Similarity | NPD29 | Approved |
0.5833 | Remote Similarity | NPD8039 | Approved |
0.5818 | Remote Similarity | NPD39 | Approved |
0.5818 | Remote Similarity | NPD4222 | Approved |
0.5789 | Remote Similarity | NPD9410 | Clinical (unspecified phase) |
0.5781 | Remote Similarity | NPD1145 | Discontinued |
0.5667 | Remote Similarity | NPD3172 | Approved |
PubChem CID   | 7778 |
ChEMBL   | CHEMBL3184928 |
ZINC   |
Molecular Weight:   | 184.15 |
ALogP:   | 1.7644 |
MLogP:   | 2.45 |
XLogP:   | 3.79 |
# Rotatable Bonds:   | 10 |
Polar Surface Area:   | 26.3 |
# H-Bond Aceptor:   | 2 |
# H-Bond Donor:   | 0 |
# Rings:   | 0 |
# Heavy Atoms:   | 13 |